Abstract：
:Human rabies cases have been on the rise during the past few years in China and a total of 2651 cases were reported in 2004. To better understand the current rabies epidemics in China, we isolated rabies viruses from dogs and humans from five provinces and characterized these isolates genetically by sequencing the entire nucleoprotein (N) gene. Comparison of the N genes among these isolates revealed 86.6-99.9% homology and these viruses can be grouped into three lineages. Phylogenetic analysis indicates that all the Chinese isolates have a close relationship with viruses circulating in Asian canine population. When compared with rabies viruses isolated previously, the three lineages were similar to three of the four groups. Thus, our data suggest that rabies viruses currently circulating in China were similar, if not identical, to those reported in the previous epidemics.
journal_name
Virus Resjournal_title
Virus researchauthors
Zhang YZ,Xiong CL,Zou Y,Wang DM,Jiang RJ,Xiao QY,Hao ZY,Zhang LZ,Yu YX,Fu ZFdoi
10.1016/j.virusres.2006.05.010subject
Has Abstractpub_date
2006-11-01 00:00:00pages
179-88issue
2eissn
0168-1702issn
1872-7492pii
S0168-1702(06)00185-7journal_volume
121pub_type
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