Induction of virus-specific neutralizing immune response against West Nile and Japanese encephalitis viruses by chimeric peptides representing T-helper and B-cell epitopes.

abstract：:The complete cDNA sequence corresponding to the genomic RNA of a South American strain of potato virus X (PVXc) is reported. The sequence (6432 nucleotides) contains five open reading frames coding for polypeptides with molecular weights of 165.3, 24.3, 12.3, 7.6 and 25.0 and displays an overall homology of 77.4% with...

journal_title：Virus research

authors： Orman BE,Celnik RM,Mandel AM,Torres HN,Mentaberry AN

更新日期：1990-07-01 00:00:00

abstract：:Mimivirus' genome includes parts of 5S, 16S and 23S ribosomal RNAs encoded by Acanthamoeba's mitogenome, the giant virus' host. Two non-exclusive hypotheses for rRNA remnants in giant viruses are examined: 1. mitogenomes invade viral genomes as they do for nuclear chromosomes (producing numts); 2. megaviral genomes ev...

journal_title：Virus research

authors： Seligmann H

更新日期：2018-07-15 00:00:00

abstract：:The complete nucleotide sequence of an enterovirus 77 isolate is reported. The virus designated FR/CF496-99 (France/Clermont-Ferrand 496-1999) was recovered from the feces of a 4-year-old child hospitalized for Salmonella gastroenteritis. The virus was identified by a molecular typing assay based on the genomic sequen...

journal_title：Virus research

authors： Bailly JL,Cardoso MC,Labbé A,Peigue-Lafeuille H

更新日期：2004-02-01 00:00:00

abstract：:Blackberry yellow vein disease (BYVD), a disorder caused by virus complexes, has become a major threat to fresh market blackberry production in the United States. Blackberry yellow vein associated virus (BYVaV) is the most prevalent virus in the BYVD complexes; detected in about 50% of samples exhibiting typical disea...

journal_title：Virus research

authors： Poudel B,Sabanadzovic S,Bujarski J,Tzanetakis IE

更新日期：2012-10-01 00:00:00

abstract：:The evolution of virus diseases, both their emergence and disappearance, involves complex interactions between the agent, the host, and the environment. These themes are illustrated by three examples, poliomyelitis of humans, bovine spongiform encephalopathy of cattle, and AIDS of humans. Emergence may be due to evolu...

journal_title：Virus research

authors： Nathanson N,McGann KA,Wilesmith J,Desrosiers RC,Brookmeyer R

更新日期：1993-07-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) is now classified into two distinct variants such as HHV-6 variant A(HHV-6A) and B(HHV-6B) (Ablashi et al., Arch. Virol. 129, 1993, 1-4) and the DNA of HHV-6A strain U1102 was completely sequenced (Gompels et al., Virology 209, 1995, 29-51). We have sequenced a 30-kilobase pair (kbp) (genom...

journal_title：Virus research

authors： Kosuge H,Isegawa Y,Yamanishi K

更新日期：1997-11-01 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) pandemic has created an urgent need for therapeutics that inhibit the SARS-COV-2 virus and suppress the fulminant inflammation characteristic of advanced illness. Here, we describe the anti-COVID-19 potential of PTC299, an orally bioavailable compound that is a potent inhibitor ...

journal_title：Virus research

authors： Luban J,Sattler RA,Mühlberger E,Graci JD,Cao L,Weetall M,Trotta C,Colacino JM,Bavari S,Strambio-De-Castillia C,Suder EL,Wang Y,Soloveva V,Cintron-Lue K,Naryshkin NA,Pykett M,Welch EM,O'Keefe K,Kong R,Goodwin E,Jac

更新日期：2021-01-15 00:00:00

abstract：:The genetic and antigenic characteristics of the Amur (AMR) and Far East (FE) virus lineages, which are both within the genus Hantavirus, were studied. Representative viruses, H5 and B78 for AMR and Bao 14 for FE, were used. The entire small (S) and medium (M) segments, except for the 3'- and 5'-ends, were sequenced. ...

journal_title：Virus research

authors： Lokugamage K,Kariwa H,Lokugamage N,Miyamoto H,Iwasa M,Hagiya T,Araki K,Tachi A,Mizutani T,Yoshimatsu K,Arikawa J,Takashima I

更新日期：2004-05-01 00:00:00

abstract：:We have recently identified and sequenced a molecular clone of the serogroup 2 simian retrovirus (SRV), D2/RHE/OR/V1, that retains an enhanced ability to infect specific T cell lines. In this report, using deletion mutagenesis, we localized the psi packaging signal, necessary for packaging of D2/RHE/OR/V1 particles, t...

journal_title：Virus research

authors： Li B,Nguyen S,Li X,Machida CA

更新日期：2001-06-01 00:00:00

abstract：:We have used the polymerase chain reaction (PCR) to obtain sensitive detection and identification of poliovirus RNA genomes. Primer pairs were designed to permit identification of each Sabin poliovaccine strain by the electrophoretic mobilities of the amplified DNA products (Sabin 1: 97 bp; Sabin 2: 71 bp; Sabin 3: 44...

journal_title：Virus research

authors： Yang CF,De L,Holloway BP,Pallansch MA,Kew OM

更新日期：1991-07-01 00:00:00

abstract：:The main objective of this narrative review is to describe the available evidence on the possible antiviral activity of ozone in patients with COVID-19 and its therapeutic applicability through hospital protocols. Amongst different possible therapies for SARS-CoV-2 pneumonia, ozone therapy seems to have an immunologic...

journal_title：Virus research

authors： Cattel F,Giordano S,Bertiond C,Lupia T,Corcione S,Scaldaferri M,Angelone L,De Rosa FG

更新日期：2021-01-02 00:00:00

abstract：:Sequence analyses of VP3 gene segments of Wongorr virus isolates from the Northern Territory of Australia were compared with the cognate gene segments from Picola and Paroo River viruses. Previous serological investigations had demonstrated some relationships between these viruses, however VP3 gene sequence and phylog...

journal_title：Virus research

authors： Parkes H,Gould AR

更新日期：1996-10-01 00:00:00

abstract：:An Olive latent virus 1 isolate designated GM6, obtained from a Portuguese olive tree, was characterized and the coat protein gene sequenced and analysed. The purified virus particles showed to be isometric with ca. 30 nm in diameter and contained a single-stranded RNA species with ca. 3.7 kb. The dsRNA profile obtain...

journal_title：Virus research

authors： Félix MR,Cardoso JM,Oliveira S,Clara MI

更新日期：2005-03-01 00:00:00

abstract：:One of the essential steps in canine parvovirus (CPV) infection, the release from endosomal vesicles, is dominated by interactions between the virus capsid and the endosomal membranes. In this study, the effect of sphingomyelin and phosphatidyl serine on canine parvovirus capsid and on the phospholipase A(2) (PLA(2)) ...

journal_title：Virus research

authors： Pakkanen K,Karttunen J,Virtanen S,Vuento M

更新日期：2008-03-01 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSE) are a heterogeneous group of neurodegenerative disorders. The common feature of these diseases is the pathological conversion of the normal cellular prion protein (PrP(C)) into a β-structure-rich conformer-termed PrP(Sc). The latter can induce a self-perpetuating process...

journal_title：Virus research

authors： Le NT,Narkiewicz J,Aulić S,Salzano G,Tran HT,Scaini D,Moda F,Giachin G,Legname G

更新日期：2015-09-02 00:00:00

abstract：:Plant viruses express RNA silencing suppressor (RSS) proteins to counteract plant defence mechanisms. Here, we describe a method to assess the RSS activity based on an alfalfa mosaic virus (AMV) RNA 3 expression vector and transgenic Nicotiana tabacum plants that express the P1 and P2 subunits of the AMV replicase (P1...

journal_title：Virus research

authors： Martínez-Pérez M,Navarro JA,Pallás V,Sánchez-Navarro JA

更新日期：2019-10-15 00:00:00

abstract：:DNA clones representing the small genomic segment of Nephropathia epidemica virus strain Hällnäs B1 (NEV) and Hantaan virus strain 76-118 (HTV) encoding their nucleocapsid proteins were inserted into the E. coli vector pIN-III-ompA for secretion of proteins into the periplasmic space. The complete HTV and NEV nucleoca...

journal_title：Virus research

authors： Gött P,Zöller L,Yang S,Stohwasser R,Bautz EK,Darai G

更新日期：1991-03-01 00:00:00

abstract：:Theiler's murine encephalomyelitis virus is divided into two subgroups on the basis of their different biological activities. GDVII subgroup strains cause acute and fatal encephalomyelitis in mice, while TO or DA subgroup strains cause non-fatal polioencephalomyelitis in weanling mice followed by virus persistence and...

journal_title：Virus research

authors： Ichinose-Asakura K,Taniura N,Himeda T,Nojiri M,Okuwa T,Ohara Y

更新日期：2010-02-01 00:00:00

abstract：:The sequence of the 3' 1462nts of RNA-1 of a UK isolate of the fungal-transmitted virus barley mild mosaic (BaMMV) has been determined. An open reading frame encoding the coat protein gene was identified within this region using amino acid sequence information obtained by cyanogen bromide cleavage of virus particles. ...

journal_title：Virus research

authors： Foulds IJ,Lea VJ,Sidebottom C,James CM,Boulton RE,Brears T,Slabas AR,Jack PL,Stratford R

更新日期：1993-01-01 00:00:00

abstract：:The highly heterogeneous porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent responsible for an economically important pig disease with the characteristic symptoms of reproductive losses in breeding sows and respiratory illnesses in young piglets. The virus can be broadly divided into th...

journal_title：Virus research

authors： Lu ZH,Archibald AL,Ait-Ali T

更新日期：2014-12-19 00:00:00

abstract：:We have previously reported effective gene silencing of a transgene and endogenous plant genes in tobacco and tomato plants using a modified viral satellite DNA associated with Tomato yellow leaf curl China virus (TYLCCNV). In this study, we constructed a similar gene silencing vector (DNADeltaC12beta) based on the sa...

journal_title：Virus research

authors： Qian Y,Mugiira RB,Zhou X

更新日期：2006-06-01 00:00:00

abstract：:Zika virus is an emergent arbovirus that has caused a public health emergency in South America. Zika virus infection is known to cause microcephaly and other congenital defects and Guillain-Barré syndrome. Unfortunately no direct antiviral treatments are available at present. IFN-stimulated gene 15 (ISG15) is one of t...

journal_title：Virus research

authors： Wang Y,Ren K,Li S,Yang C,Chen L

更新日期：2020-10-02 00:00:00

abstract：:The morbidity and mortality of coxsackievirus A10 (CVA10)-associated hand, foot, and mouth disease (HFMD) have been increasing in recent years, while few studies on the vaccine and animal model of CVA10 have been reported. Here, we first established a CVA10-infected gerbil model and employed it to evaluate the immunop...

journal_title：Virus research

authors： Chen C,Xia Y,Zhu S,Xu F,Sun Y,Lu H,Gao M,Yang Z,Mao Z,Ge Q,Miao Z,Zhu H,Yao P

更新日期：2020-09-01 00:00:00

abstract：:Recently, we described the isolation and characterisation of the novel lepidopteran transposon TCp3.2, which was found to be inserted into the genome of a spontaneous mutant of the baculovirus Cydia pomonella granulovirus (CpGV). Transposon TCp3.2, which is a member of the Tcl/mariner superfamily, is an apparently def...

journal_title：Virus research

authors： Jehle JA,van der Linden IF,Backhaus H,Vlak JM

更新日期：1997-08-01 00:00:00

abstract：:Detection of Chronic bee paralysis virus (CBPV) is reported for the first time in two species of ants (Camponotus vagus and Formica rufa) and in Varroa destructor. A quantitative real-time PCR (qPCR) method was used to detect and quantify CBPV in infected bees, ants and mites. A minus-strand-specific RT-PCR was used t...

journal_title：Virus research

authors： Celle O,Blanchard P,Olivier V,Schurr F,Cougoule N,Faucon JP,Ribière M

更新日期：2008-05-01 00:00:00

abstract：:A recombinant baculovirus, the genome of which contains DNA encoding Marek's disease virus serotype 1 (MDV1) homolog of glycoprotein D (gD) of herpes simplex virus under the polyhedrin promoter was constructed and designated rAcMDV1gD. Five monoclonal antibodies (MAbs) which recognize the MDV1 homolog of gD (MDV1 gD) ...

journal_title：Virus research

authors： Ono M,Jang HK,Maeda K,Kawaguchi Y,Tohya Y,Niikura M,Mikami T

更新日期：1995-10-01 00:00:00

abstract：:In order to investigate the functional properties of the UL56 gene of herpes simplex virus type 1 (HSV-1), it was necessary to express the UL56 protein in vitro. The DNA sequences corresponding to the open reading frame of the UL56 gene of HSV-1 strain F were amplified from genomic viral DNA by PCR using primers corre...

journal_title：Virus research

authors： Kehm R,Lorentzen E,Rösen-Wolff A,Darai G

更新日期：1994-07-01 00:00:00

abstract：:In recent years, the spread of Duck Hepatitis A Viruses (DHAVs) has represented a serious threat and significant economic impact in duck industry of China. The sixteen reported DHAV isolates (15 DHAV-1 strains and one DHAV-3) were identified from infected ducks with clinical symptoms in China between 2009 and 2012. In...

journal_title：Virus research

authors： Li J,Bi Y,Chen C,Yang L,Ding C,Liu W

更新日期：2013-12-26 00:00:00

abstract：BACKGROUND AND AIM:The mechanisms of hepatocarcinogenesis induced by hepatitis C virus remain unclear. Our aim was to investigate the effect of the HCV core protein on the promoter methylation status of selected genes potentially involved in the hepatocellular carcinoma (HCC). MATERIALS AND METHODS:We evaluated the pr...

journal_title：Virus research

authors： Ripoli M,Barbano R,Balsamo T,Piccoli C,Brunetti V,Coco M,Mazzoccoli G,Vinciguerra M,Pazienza V

更新日期：2011-09-01 00:00:00

abstract：:In situ hybridization and virus titration were used to characterize early stages of rat virus (RV) infection of rat pups after oronasal inoculation. Results suggest that virus enters through the lung and that early viremia leads rapidly to pantropic infection. Cells derived from all three germ layers were infected wit...

journal_title：Virus research

authors： Gaertner DJ,Jacoby RO,Johnson EA,Paturzo FX,Smith AL,Brandsma JL

更新日期：1993-04-01 00:00:00