Abstract:
:Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important role in both normal biological activity and pathological processes such as viral infection and tumorigenesis. LncRNAs and miRNAs are the most important elements of ncRNAs and function as vital regulatory elements. Their complex regulatory relationship has therefore attracted a lot of attention. In this review, we address the generation, classification, and regulatory mechanisms of lncRNAs and miRNAs in the interaction between virus and host, focusing on their mutual regulation in viral replication and pathogenesis. In-depth analysis of the underlying mechanisms will provide new information for the prevention of viral infections and development of antiviral drugs.
journal_name
Virus Resjournal_title
Virus researchauthors
Chen L,Zhou Y,Li Hdoi
10.1016/j.virusres.2018.08.018subject
Has Abstractpub_date
2018-09-15 00:00:00pages
25-32eissn
0168-1702issn
1872-7492pii
S0168-1702(18)30282-Xjournal_volume
257pub_type
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