当前位置： SCI文献检索 > VIRUS RESEARCH期刊下所有文献 > Beta-actin interacts with the E2 protein and is involved in the early replication of classical swine fever virus.

Beta-actin interacts with the E2 protein and is involved in the early replication of classical swine fever virus.

Abstract：

:The E2 glycoprotein of classical swine fever virus (CSFV) is involved in viral infection and induction of neutralizing antibodies. Little is known about how E2 interacts with host cells. To understand the cellular factors involved in viral replication cycle, E2 was used as bait in yeast two-hybrid screens, resulting in the identification of β-actin as a potential E2-interacting partner. E2-β-actin interaction was confirmed by co-immunoprecipitation, GST pulldown, laser confocal and bimolecular fluorescence complementation assays. The E2-interacting domain of β-actin was mapped to amino acids (aa) 95-188 and two β-actin-interacting regions were identified in E2 (aa 182-261 and aa 262-341). Knockdown of β-actin by RNA interference and disruption of filamentous β-actin with cytochalasin D at 4h post-infection caused a significant reduction of viral RNA copies and titers. Collectively, the results indicated that β-actin is involved in the early replication of CSFV.

journal_name

Virus Res

journal_title

Virus research

authors

He F,Ling L,Liao Y,Li S,Han W,Zhao B,Sun Y,Qiu HJ

doi

10.1016/j.virusres.2013.10.016

subject

Has Abstract

pub_date

2014-01-22 00:00:00

pages

161-8

eissn

0168-1702

issn

1872-7492

pii

S0168-1702(13)00363-8

journal_volume

179

pub_type

杂志文章

相关文献

VIRUS RESEARCH文献大全
  • Identification of RNA instability elements in Borna disease virus.

    abstract：:Genome organization and gene expression of Borna disease virus (BDV) are remarkable for the overlap of open reading frames, transcription units and transcription signals, readthrough of transcription termination signals, differential use of translation initiation codons, and exploitation of the cellular splicing machi...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2009.03.016

    authors： Siemetzki U,Ashok MS,Briese T,Lipkin WI

    更新日期：2009-09-01 00:00:00

  • The immune response to measles virus in mice. T-helper response to the nucleoprotein and mapping of the T-helper epitopes.

    abstract：:The T-helper response to the measles virus nucleoprotein (NP) has been studied in mice. The T-cell proliferative response was measured in lymphocytes from mice immunized with either a vaccinia measles-NP recombinant virus or a mouse neuro-adapted measles virus. A T-cell response was obtained with lymphocytes from H2d ...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(92)90088-q

    authors： Giraudon P,Buckland R,Wild TF

    更新日期：1992-01-01 00:00:00

  • Expression cloning and antigenic analysis of the nucleocapsid protein of equine arteritis virus.

    abstract：:A series of recombinant fusion proteins derived from equine arteritis virus (EAV) open reading frame (ORF) 7 have been used to define the immunoreactive region of the viral nucleocapsid (N) protein. Reactivities of recombinant N fusion proteins with post-infection equine sera in immunoblots and ELISAs indicate that th...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(95)00098-4

    authors： Chirnside ED,Francis PM,Mumford JA

    更新日期：1995-12-01 00:00:00

  • Development of fetal and placental innate immune responses during establishment of persistent infection with bovine viral diarrhea virus.

    abstract：:Transplacental viral infections are dependent upon complex interactions between feto-placental and maternal immune responses and the stage of fetal development at which the infection occurs. Bovine viral diarrhea virus (BVDV) has the ability to cross the placenta and infect the fetus. Infection early in gestation with...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2012.05.018

    authors： Smirnova NP,Webb BT,Bielefeldt-Ohmann H,Van Campen H,Antoniazzi AQ,Morarie SE,Hansen TR

    更新日期：2012-08-01 00:00:00

  • Plant subviral RNAs as a long noncoding RNA (lncRNA): Analogy with animal lncRNAs in host-virus interactions.

    abstract：:Satellite RNAs (satRNAs) and viroids belong to the group called subviral agents and are the smallest pathogens of plants. In general, small satRNAs and viroids are 300-400 nt in size and do not encode any functional proteins; they are thus regarded as so-called long noncoding RNAs (lncRNAs). These lncRNAs are receivin...

    journal_title：Virus research

    pub_type： 杂志文章,评审

    doi：10.1016/j.virusres.2015.06.016

    authors： Shimura H,Masuta C

    更新日期：2016-01-02 00:00:00

  • DNA-binding proteins of baculovirus-infected cells during permissive and semipermissive replication.

    abstract：:Certain insect cell lines have been shown to be permissive (TN-368) or semipermissive (IPLB-LD-652Y) for Autographa californica nuclear polyhedrosis virus (AcMNPV) replication (McClintock et al., 1986b). In this report DNA-binding proteins were identified in such cell:virus systems by hybridizing Western blots contain...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(91)90105-5

    authors： McClintock JT,Guzo D,Guthrie KP,Dougherty EM

    更新日期：1991-07-01 00:00:00

  • Synthetic prions and other human neurodegenerative proteinopathies.

    abstract：:Transmissible spongiform encephalopathies (TSE) are a heterogeneous group of neurodegenerative disorders. The common feature of these diseases is the pathological conversion of the normal cellular prion protein (PrP(C)) into a β-structure-rich conformer-termed PrP(Sc). The latter can induce a self-perpetuating process...

    journal_title：Virus research

    pub_type： 杂志文章,评审

    doi：10.1016/j.virusres.2014.10.020

    authors： Le NT,Narkiewicz J,Aulić S,Salzano G,Tran HT,Scaini D,Moda F,Giachin G,Legname G

    更新日期：2015-09-02 00:00:00

  • Comparative analysis of the attachment protein gene (H) of dolphin morbillivirus.

    abstract：:DMV, dolphin morbillivirus, a paramyxovirus of uncertain origin recently emerged in Mediterranean dolphins. This study presents the complete nucleotide sequence of the hemagglutinin (H) gene including the gene boundaries. The single open reading frame of the DMV H gene encodes a protein of 604 residues which exhibits ...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(95)01254-0

    authors： Blixenkrone-Møller M,Bolt G,Jensen TD,Harder T,Svansson V

    更新日期：1996-01-01 00:00:00

  • Trans-activation of viral tk promoters by proteins encoded by varicella zoster virus open reading frames 61 and 62.

    abstract：:Plasmids containing the varicella zoster virus (VZV) open reading frames (ORFs) 61 and 62 were used in a transient co-transfection assay to test for trans-activation of the VZV and herpes simplex virus type 1 (HSV-1) thymidine kinase (tk) promoters. The trans-activating potential of the polypeptides encoded by these V...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(90)90013-2

    authors： Cabirac GF,Mahalingam R,Wellish M,Gilden DH

    更新日期：1990-01-01 00:00:00

  • Immunoelectron microscopic localization of herpes simplex virus glycoprotein gB in the nuclear envelope of infected cells.

    abstract：:Herpesvirus, such as herpes simplex type 1 (HSV-1) acquire their envelope by budding through a modified inner membrane of the nuclear envelope which forms thick and dense patches at the site of budding. This suggests that some of the viral envelope glycoproteins must be transported to the nuclear envelope in order to ...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(93)90023-g

    authors： Gilbert R,Ghosh HP

    更新日期：1993-06-01 00:00:00

  • Cucurbit chlorotic yellows virus p22 suppressor of RNA silencing binds single-, double-stranded long and short interfering RNA molecules in vitro.

    abstract：:Cucurbit chlorotic yellows virus (CCYV) is a new member of the genus Crinivirus (family Closteroviridae) with a bi-partite genome. CCYV RNA 1-encoded p22 has recently been reported to be a weak local suppressor of RNA silencing for which an interaction with cucumber SKP1LB1 through an F-box-like motif was demonstrated...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2020.197887

    authors： Salavert F,Navarro JA,Owen CA,Khechmar S,Pallás V,Livieratos IC

    更新日期：2020-04-02 00:00:00

  • Correlation of cellular factors and differential scrapie prion permissiveness in ovine microglia.

    abstract：:Prion diseases are fatal neurodegenerative disorders by which the native cellular prion protein (PrPC) is misfolded into an accumulating, disease-associated isoform (PrPD). To improve the understanding of prion pathogenesis and develop effective treatments, it is essential to elucidate factors contributing to cellular...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2017.07.016

    authors： Dinkel KD,Schneider DA,Muñoz-Gutiérrez JF,McElliott VR,Stanton JB

    更新日期：2017-08-15 00:00:00

  • Differential susceptibility of resting CD4(+) T lymphocytes to a T-tropic and a macrophage (M)-tropic human immunodeficiency virus type 1 is associated with their surface expression of CD38 molecules.

    abstract：:Recent evidence has accumulated which definitively shows that chemokine receptors CCR5 and CXCR4 play an essential role as coreceptors for human immunodeficiency virus type 1 (HIV-1) infection. Flow cytometric analysis permitted us to detect CD38, a surface marker of early differentiation, as well as activation of T c...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/s0168-1702(00)00220-3

    authors： Horikoshi H,Kinomoto M,Sasao F,Mukai T,Luftig RB,Ikuta K

    更新日期：2001-01-01 00:00:00

  • Characterization of haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus expressed by a recombinant baculovirus.

    abstract：:A recombinant baculovirus containing a cDNA which encodes haemagglutinin-neuraminidase (HN) of Newcastle disease virus (NDV) was constructed. Spodoptera frugiperda cells infected with this recombinant virus produced a large amount of HN glycoprotein similar to the authentic HN in size. The recombinant HN glycoprotein ...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(91)90059-5

    authors： Niikura M,Matsuura Y,Hattori M,Onuma M,Mikami T

    更新日期：1991-06-01 00:00:00

  • Molecular characterization of a novel reassortment Mammalian orthoreovirus type 2 isolated from a Florida white-tailed deer fawn.

    abstract：:Mammalian orthoreovirus (MRV) is the type species of the genus Orthoreovirus and causes a range of significant respiratory, nervous or enteric diseases in humans and animals. In 2016 a farmed white-tailed deer (Odocoileus virginianus) fawn became ill, displaying clinical signs of lethargy, dehydration, and profuse fou...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2019.197642

    authors： Ahasan MS,Subramaniam K,Sayler KA,Loeb JC,Popov VL,Lednicky JA,Wisely SM,Campos Krauer JM,Waltzek TB

    更新日期：2019-09-01 00:00:00

  • Evidence for the assignment of two strains of SPLV to the genus Potyvirus based on coat protein and 3' non-coding region sequence data.

    abstract：:The use of potyvirus-specific primers and subsequent application of the RACE procedure allowed the cloning of the 3' terminal 1088 nucleotides of the genomic RNA of the Taiwan isolate of sweetpotato latent virus (SPLV-T) and the 3' genomic 1085 nucleotides of a SPLV-like virus from China (SPLV-CH). The sequence of an ...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/s0168-1702(97)01456-1

    authors： Colinet D,Kummert J,Lepoivre P

    更新日期：1997-05-01 00:00:00

  • The avian and mammalian host range of highly pathogenic avian H5N1 influenza.

    abstract：:Highly pathogenic H5N1 influenza viruses have been isolated from a number of avian and mammalian species. Despite intensive control measures the number of human and animal cases continues to increase. A more complete understanding of susceptible species and of contributing environmental and molecular factors is crucia...

    journal_title：Virus research

    pub_type： 杂志文章,评审

    doi：10.1016/j.virusres.2013.09.004

    authors： Kaplan BS,Webby RJ

    更新日期：2013-12-05 00:00:00

  • Control of HIV-1 replication by RNA interference.

    abstract：:Small interfering RNAs (siRNAs) have been shown to direct sequence-specific inhibition of gene expression in mammalian cells. siRNAs are RNA duplexes of 21-23 nucleotides (nts) with approximately 2nt 3' overhangs that can induce degradation of their homologous target mRNAs without interferon responses in mammalian cel...

    journal_title：Virus research

    pub_type： 杂志文章,评审

    doi：10.1016/j.virusres.2004.01.015

    authors： Lee NS,Rossi JJ

    更新日期：2004-06-01 00:00:00

  • Expression of antisense RNA fails to inhibit influenza virus replication.

    abstract：:Cell lines were constructed which permanently express influenza virus-specific RNA. Two approaches were followed. C127 cells were transformed with bovine papilloma virus (BPV) vectors and the resulting cell lines were found to inhibit the replication of influenza virus at low multiplicity of infection (MOI 0.05). Howe...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(89)90035-x

    authors： Leiter JM,Krystal M,Palese P

    更新日期：1989-10-01 00:00:00

  • A new Clethrionomys-derived hantavirus from Germany: evidence for distinct genetic sublineages of Puumala viruses in Western Europe.

    abstract：:Puumala (PUU) viruses are the predominant etiologic agents of hantavirus infections in Europe. The most important reservoir is the bank vole, Clethrionomys glareolus (Cg), belonging to the subfamily Arvicolinae of the Muridae family. Here we report on the molecular characterization of the first rodent-derived sequence...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/s0168-1702(99)00024-6

    authors： Heiske A,Anheier B,Pilaski J,Volchkov VE,Feldmann H

    更新日期：1999-06-01 00:00:00

  • Dissecting the role of integrin subunits alpha 2 and beta 3 in rotavirus cell entry by RNA silencing.

    abstract：:Several cell surface molecules have been implicated in rotavirus cell entry, however, their individual relevance during this process is unknown. In this work, the expression of integrins alpha2, beta2, and alpha v beta 3, the heat shock cognate protein 70, and of ganglioside GM1 in different cell lines of human and si...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2009.07.013

    authors： Isa P,Sánchez-Alemán MA,López S,Arias CF

    更新日期：2009-11-01 00:00:00

  • Effect of lysosomotropic compounds on early events in foot-and-mouth disease virus replication.

    abstract：:The effect of three lysosomotropic compounds, chloroquine, monensin and NH4Cl, on the replication of foot-and-mouth disease virus (FMDV) type A12 was studied. Viral replication was almost totally inhibited by 0.5 mM chloroquine, 50 microM monensin, or 25 mM NH4Cl. Monensin and NH4Cl affected replication when added eit...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(87)90032-3

    authors： Baxt B

    更新日期：1987-05-01 00:00:00

  • Characterization of a SHIV162P3 variant evolved in an infected rhesus macaque with persistent plasma viremia.

    abstract：:Typically plasma viremia is controlled in macaques challenged with R5 tropic SHIV162P3 during the chronic phase of infection. However, in a few infected animals it sustains for a prolonged period. Persistent plasma viremia in two such macaques led to a rapid decline of CD4+ T-cells in blood leading to the induction of...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2010.04.006

    authors： Chung HK,Suschak J,Galmin L,Rose N,Pal R

    更新日期：2010-08-01 00:00:00

  • Identification and sequence analysis of the integration site of transposon TCp3.2 in the genome of Cydia pomonella granulovirus.

    abstract：:Recently, we described the isolation and characterisation of the novel lepidopteran transposon TCp3.2, which was found to be inserted into the genome of a spontaneous mutant of the baculovirus Cydia pomonella granulovirus (CpGV). Transposon TCp3.2, which is a member of the Tcl/mariner superfamily, is an apparently def...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/s0168-1702(97)00066-x

    authors： Jehle JA,van der Linden IF,Backhaus H,Vlak JM

    更新日期：1997-08-01 00:00:00

  • The nucleotide and deduced amino acid sequence of the M gene of phocid distemper virus (PDV). The most conserved protein of morbilliviruses shows a uniquely close relationship between PDV and canine distemper virus.

    abstract：:The nucleotide sequence of the matrix gene (M) of a recently identified morbillivirus, phocid distemper virus (PDV), was determined and the amino acid composition deduced. The M gene of PDV shared many characteristics with the corresponding gene in other morbilliviruses. The nucleotide homology with the closely relate...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/0168-1702(92)90064-g

    authors： Sharma B,Norrby E,Blixenkrone-Möller M,Kövamees J

    更新日期：1992-04-01 00:00:00

  • Phylogenetic analysis of the RNA-dependent RNA polymerase (RdRp) and a predicted structural protein (pSP) of the Chronic bee paralysis virus (CBPV) isolated from various geographic regions.

    abstract：:Chronic bee paralysis virus (CBPV) is responsible for chronic paralysis, an infectious and contagious disease of adult honey bees (Apis mellifera L.). The full-length nucleotide sequences of the two major RNAs of CBPV have previously been characterized. The Orf3 of RNA1 has shown significant similarities to the RNA-de...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2009.04.025

    authors： Blanchard P,Schurr F,Olivier V,Celle O,Antùnez K,Bakonyi T,Berthoud H,Haubruge E,Higes M,Kasprzak S,Koeglberger H,Kryger P,Thiéry R,Ribière M

    更新日期：2009-09-01 00:00:00

  • The protein-protein interactions between Amsacta moorei entomopoxvirus (AMEV) protein kinases (PKs) and all viral proteins.

    abstract：:Entomopoxviruses are an important group of viruses infecting only insects. They belong to Poxviridae which infect both invertebrates and vertebrates, including humans. Protein kinases are known to have roles at virus morphogenesis, host selectivity, the regulation of cell division and apoptosis in some vertebrate poxv...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2018.02.007

    authors： Danismazoglu M,Nalcacioglu R,Muratoglu H,Demirbag Z

    更新日期：2018-03-15 00:00:00

  • Host cell targets for African swine fever virus.

    abstract：:Viruses are strict intracellular pathogens that require the cellular environment to complete a successful infection. Among them, African swine fever virus (ASFV) is an evolutionary ancient DNA virus, endemic in Africa, which is nowadays causing an emergent disease in Europe with a potential high economic impact in the...

    journal_title：Virus research

    pub_type： 杂志文章,评审

    doi：10.1016/j.virusres.2015.05.026

    authors： Muñoz-Moreno R,Galindo I,Cuesta-Geijo MÁ,Barrado-Gil L,Alonso C

    更新日期：2015-11-02 00:00:00

  • Characterization of the structural proteins of hepatitis C virus expressed by an adenovirus recombinant.

    abstract：:Human adenoviruses have been used for mammalian expression vectors and recombinant vaccines for heterologous antigens. We constructed and characterized an infectious adenovirus recombinant containing core-E1-E2 genes of hepatitis C virus (HCV). The core protein was produced mainly during the early phase of viral infec...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/s0168-1702(98)00043-4

    authors： Seong YR,Lee CH,Im DS

    更新日期：1998-06-01 00:00:00

  • Induction of autophagy enhances porcine reproductive and respiratory syndrome virus replication.

    abstract：:Autophagy is an evolutionarily conserved lysosome-dependent degradation pathway that acts in the maintenance of cellular homeostasis and plays important functions in viral replication and pathogenesis. In this study, we investigated the role of autophagy in the replication of porcine reproductive and respiratory syndr...

    journal_title：Virus research

    pub_type： 杂志文章

    doi：10.1016/j.virusres.2011.11.008

    authors： Chen Q,Fang L,Wang D,Wang S,Li P,Li M,Luo R,Chen H,Xiao S

    更新日期：2012-02-01 00:00:00