Abstract：
:The epitopes of six monoclonal antibodies generated against type A12 foot-and-mouth disease virus (FMDV) VP1 or its largest cyanogen bromide fragment (13 kd) were characterized. Five of these monoclonal antibodies neutralized viral infectivity. Solid-phase and competitive antigen binding assays using virion-derived antigens or a biosynthetic VP1 polypeptide identified two distinct neutralizing epitopes. One epitope was located between amino acid residues 145-168 of VP1 and the other between amino acids 169-179. The results indicate that antibodies reacting with two distinct areas of the VP1 polypeptide are capable of neutralizing FMD virus.
journal_name
Virus Resjournal_title
Virus researchauthors
Robertson BH,Morgan DO,Moore DMdoi
10.1016/0168-1702(84)90006-6subject
Has Abstractpub_date
1984-09-01 00:00:00pages
489-500issue
6eissn
0168-1702issn
1872-7492pii
0168-1702(84)90006-6journal_volume
1pub_type
杂志文章相关文献
VIRUS RESEARCH文献大全abstract：:A transmissible disease of the plant pathogenic fungus Helminthosporium victoriae, the causal agent of Victoria blight of oats, was reported more than 50 years ago. Diseased, but not normal, isolates, of H. victoriae contain two distinct viruses designated according to their sedimentation values as victorivirus Helmin...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2015.12.011
更新日期：2016-02-02 00:00:00
abstract：:Confocal microscopy revealed that Rice dwarf virus (RDV) initially accumulated in epithelial cells of the filter chamber of leafhopper vector Nephotettix cincticeps 2 days after acquisition access feeding on diseased plants. Subsequently, RDV accumulation progressed to the anterior midgut, and then spread to the nervo...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2011.04.028
更新日期：2011-09-01 00:00:00
abstract：:The human T-lymphotropic virus type-1 (HTLV-1) is the causative agent of a chronic progressive myelopathy (TSP/HAM) in which lesions of the central nervous system (CNS) are associated with infiltration of HTLV-1-infected T-cells. In a model that mimics the interaction between glial and T-cells, we show that transient ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/s0168-1702(01)00284-2
更新日期：2001-10-30 00:00:00
abstract：BACKGROUND:The role of occult hepatitis B virus (HBV) infection and Torque teno virus (TTV) infection in the development of hepatocellular carcinoma (HCC) in chronic hepatitis C patients is still uncertain. AIM:The aim of the present study was to investigate the prevalence and significance of OBI and TTV infection, an...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2017.09.022
更新日期：2017-10-15 00:00:00
abstract：:JCPyV and BKPyV are common human polyomaviruses that cause lifelong asymptomatic persistent infections in their hosts. In immunosuppressed individuals, increased replication of JCPyV and BKPyV cause significant disease. JCPyV causes a fatal and rapidly progressing demyelinating disease known as progressive multifocal ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2014.06.008
更新日期：2014-08-30 00:00:00
abstract：:One of the essential steps in canine parvovirus (CPV) infection, the release from endosomal vesicles, is dominated by interactions between the virus capsid and the endosomal membranes. In this study, the effect of sphingomyelin and phosphatidyl serine on canine parvovirus capsid and on the phospholipase A(2) (PLA(2)) ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2007.10.008
更新日期：2008-03-01 00:00:00
abstract：:The use of potyvirus-specific primers and subsequent application of the RACE procedure allowed the cloning of the 3' terminal 1088 nucleotides of the genomic RNA of the Taiwan isolate of sweetpotato latent virus (SPLV-T) and the 3' genomic 1085 nucleotides of a SPLV-like virus from China (SPLV-CH). The sequence of an ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/s0168-1702(97)01456-1
更新日期：1997-05-01 00:00:00
abstract：:Rapidly evolving RNA viruses prevail within a host as a collection of closely related variants, referred to as viral quasispecies. Advances in high-throughput sequencing (HTS) technologies have facilitated the assessment of the genetic diversity of such virus populations at an unprecedented level of detail. However, a...
journal_title：Virus research
pub_type： 杂志文章,评审
doi：10.1016/j.virusres.2016.09.016
更新日期：2017-07-15 00:00:00
abstract：:While large-scale dog vaccination campaigns have significantly reduced urban rabies throughout Mexico, reports of sylvatic rabies, including cases of spill-over of bat strains into livestock and humans, are increasing. To improve knowledge of these epidemiological trends, 64 Mexican rabies virus isolates from various ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2005.10.006
更新日期：2006-05-01 00:00:00
abstract：:The human poliovirus receptor (PVR) is a cell surface protein with a multitude of functions in human biology. PVR was initially identified as the receptor for the human poliovirus and recent discoveries have given a greater insight into both its morphology and its function. Alternative splicing of the PVR gene results...
journal_title：Virus research
pub_type： 杂志文章,评审
doi：10.1016/j.virusres.2017.09.001
更新日期：2017-10-15 00:00:00
abstract：:To study the process of feline immunodeficiency virus (FIV) assembly, we examined the suitability of the vaccinia vector system to reproduce FIV particle formation. To this end, we constructed a recombinant vaccinia virus carrying the FIV gag gene. Biochemical and electron microscopy analyses of cells infected with th...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/s0168-1702(01)00249-0
更新日期：2001-07-01 00:00:00
abstract：:It has previously been shown that the shortest RNA (RNA 7) of influenza C viruses codes for a nonstructural (NSI) protein (Nakada et al. (1985) J. Virol. 56, 221-226). Experiments reported here indicate that RNA 7 also directs the synthesis of a second nonstructural protein via a spliced mRNA. The amino terminal 62 co...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/0168-1702(86)90005-5
更新日期：1986-05-01 00:00:00
abstract：:Infectious spleen and kidney necrosis virus (ISKNV) is a typical species of the genus Megalocytivirus in the family Iridoviridae. However, until recently, no suitable piscine cell line is stably susceptible to ISKNV. Here, a continuous cell culture derived from the mandarin fish fry (MFF-1) was developed and has been ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2008.04.004
更新日期：2008-08-01 00:00:00
abstract：:We have previously reported effective gene silencing of a transgene and endogenous plant genes in tobacco and tomato plants using a modified viral satellite DNA associated with Tomato yellow leaf curl China virus (TYLCCNV). In this study, we constructed a similar gene silencing vector (DNADeltaC12beta) based on the sa...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2005.12.003
更新日期：2006-06-01 00:00:00
abstract：:Aphid species were counted on citrus trees in orchards in Valencia, Spain, in the spring and autumn of 1997, 1998 and 1999. Moericke yellow water traps, the 'sticky shoot' method and counts of established colonies were used in extensive surveys in which 29,502 aphids were recorded and identified. Aphis spiraecola and ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2003.12.018
更新日期：2004-03-01 00:00:00
abstract：:HCV is an ideal model to study how the infected cell is altered to allow the establishment of a chronic infection. After infection, the transcriptome of the cell changes in response to the virus or to the antiviral pathways induced by infection. The cell has evolved to sense HCV soon after infection and to activate an...
journal_title：Virus research
pub_type： 杂志文章,评审
doi：10.1016/j.virusres.2015.10.001
更新日期：2016-01-02 00:00:00
abstract：:To evaluate the mechanism by which a large outbreak of porcine epidemic diarrhea (PED) occurred in Japan, where the majority of sows are vaccinated, we isolated two new strains of PED virus (PEDV) from the intestines of piglets and found that they showed greater similarity to US isolates (group II PEDV) than to the Ja...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2016.06.006
更新日期：2016-08-15 00:00:00
abstract：:Hepatitis delta virus (HDV) is an RNA virus and eight clades of HDV have been identified. HDV clade 3 (HDV-3) is isolated only in the northern area of South America. The outcome of HDV-3 infection is associated with severe fulminant hepatitis. Variations in the large delta antigen (LDAg) between HDV clade 1 (HDV-1) an...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2012.08.021
更新日期：2012-12-01 00:00:00
abstract：:We have rescued a transfectant influenza virus, NA/TAIL(-), whose neuraminidase (NA) protein lacks the predicted cytoplasmic tail. The virus was attenuated (one log10 reduction) both in tissue culture and in mouse lungs. Attenuation correlated with a 50% reduction of the level of NA in infected cells and levels of inc...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/0168-1702(95)00017-k
更新日期：1995-06-01 00:00:00
abstract：:An orange stem pitting citrus tristeza virus (CTV) isolate CTV-B165 was found to be symptomatically similar to other known CTV-VT isolates however molecular methods failed to classify it as an identifiable CTV genotype. The sequence variation of the Indian CTV-B165 isolate was compared to the three well known CTV geno...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2010.03.017
更新日期：2010-08-01 00:00:00
abstract：:We previously prepared neutralizing monoclonal antibody (MAb)-resistant (mar) mutant viruses using a laboratory strain feline infectious peritonitis virus (FIPV) 79-1146 (Kida et al., 1999). Mar mutant viruses are mutated several amino acids of the neutralizing epitope of Spike protein, compared with the parent strain...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2010.12.020
更新日期：2011-03-01 00:00:00
abstract：:Analysis of complete polyprotein-encoding sequences of the two most prevalent genotypes of hepatitis C virus (HCV-1a and HCV-1b) revealed evidence of abundant, slightly deleterious nonsynonymous variants subject to ongoing purifying selection. In the case of both HCV-1a and HCV-1b, the NS3 protein demonstrated a high ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2009.11.001
更新日期：2010-02-01 00:00:00
abstract：:The attenuated equine infectious anemia virus (EIAV) vaccine was the first attenuated lentivirus vaccine to be used in a large-scale application and has been used to successfully control the spread of equine infectious anemia (EIA) in China. To better understand the potential role of cytokines in the pathogenesis of E...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2011.06.028
更新日期：2011-09-01 00:00:00
abstract：:DNA polymerase (DNApol) is highly conserved in baculovirus and is required for viral DNA replication. However, little is known about gammabaculovirus DNApol. Here DNApol of the gammabaculovirus Neodiprion lecontei nucleopolyhedrovirus (NeleNPV) was cloned into a dnapol-null alphabaculovirus AcMNPV bacmid, creating Bac...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2019.04.005
更新日期：2019-06-01 00:00:00
abstract：:In alfalfa samples analyzed by hightroughput sequencing, four de novo assembled contigs encoding gene products showing identities to alphapartitiviruses proteins were found based on BlastX analysis. The predicted amino acid (aa) sequences of two contigs presented 99-100% identity to the RNA-dependent RNA polymerase (R...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2019.03.021
更新日期：2019-05-01 00:00:00
abstract：:The table grape variety "Waltham Cross" was infected with Leafroll and Shiraz Disease. To reveal specific viruses that are associated with the diseased plants, we used an RT-PCR-based strategy to determine partial genome sequences of these viruses. Upon cloning and sequencing of the RT-PCR products, we detected seven ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2006.10.014
更新日期：2007-03-01 00:00:00
abstract：:Fourteen isolates of bovine herpesvirus 1 (BHV-1) found representative of more than 100 isolates studied, were compared by restriction fragment pattern analyses and molecularly characterized. A number of evolutionary links between the variants originally associated with infectious bovine rhinotracheitis and the varian...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/s0168-1702(96)01383-4
更新日期：1996-12-01 00:00:00
abstract：:African swine fever virus induces in Vero cells 81 acid and 14 basic polypeptides which account for most of the information content of the virus DNA. The kinetics and the cytosine arabinoside sensitivity of the synthesis of the virus-induced polypeptides showed the existence of three classes of proteins, two early and...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/0168-1702(86)90031-6
更新日期：1986-09-01 00:00:00
abstract：:Malignant catarrhal fever is a lymphoproliferative disease of cattle and other ungulates caused by infection with gamma-herpesviruses of the genus Macavirus. These viruses do not establish a productive infection but instead replicate in a cell-associated fashion in T lymphocytes, leading to systemic immune dysregulati...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2012.08.011
更新日期：2012-10-01 00:00:00
abstract：:Rosellinia necatrix is responsible for the white rot root disease of avocado in Southern Spain. Entoleuca sp. is a fungus isolated from roots of these same trees, but it is not pathogenic in avocado. Here, we describe two new species of partitiviruses detected in isolates of the avocado sympatric fungi Entoleuca sp. a...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2020.198020
更新日期：2020-08-01 00:00:00
