Abstract:
:The purpose of this study was to test whether the region coding for subgroup envelope specificity was a determinant of oncogenic potential. An avian retrovirus recombinant was constructed to contain the envelope gene (env) determinant for subgroup A of an avian RNA tumor virus in one of the non-oncogenic, endogenous avian retroviruses, RAV-0. The results show that such a recombinant virus does not induce lymphoma when injected into susceptible, newborn chicks. Thus, it is concluded that the envelope determinant for subgroup of avian RNA tumor viruses does not determine malignant potential.
journal_name
Virus Resjournal_title
Virus researchauthors
Wright SE,Bennett DDdoi
10.1016/0168-1702(86)90048-1subject
Has Abstractpub_date
1986-11-01 00:00:00pages
173-80issue
2eissn
0168-1702issn
1872-7492pii
0168-1702(86)90048-1journal_volume
6pub_type
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