Abstract：
:It was previously reported that during serial passage of a BHK-derived cell line persistently infected with foot-and-mouth disease virus, (termed C1-BHK-Rc1) the virus became increasingly more virulent for BHK-21 cells (de la Torre et al 1988). Virus strains isolated from different cell passage levels were tested for virulence in mice and cattle. The results showed that in the course of persistence in BHK cells, FMDV became progressively less virulent for mice and cattle.
journal_name
Virus Resjournal_title
Virus researchauthors
Díez J,Hofner M,Domingo E,Donaldson AIdoi
10.1016/0168-1702(90)90084-osubject
Has Abstractpub_date
1990-12-01 00:00:00pages
3-7issue
1eissn
0168-1702issn
1872-7492pii
0168-1702(90)90084-Ojournal_volume
18pub_type
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