Abstract：
:Viral infections are dangerous diseases for human health worldwide, which lead to significant morbidity and mortality each year. Because of their importance and the lack of effective therapeutic approaches, further attempts should be made to discover appropriate alternative or complementary treatments. Melatonin, a multifunctional neurohormone mainly synthesized and secreted by the pineal gland, plays some roles in the treatment of viral infections. Regarding a deadly outbreak of COVID-19 across the world, we decided to discuss melatonin functions against various viral infections including COVID-19. Therefore, in this review, we summarize current evidence on melatonin therapy for viral infections with focus on possible underlying mechanisms of melatonin actions.
journal_name
Virus Resjournal_title
Virus researchauthors
Bahrampour Juybari K,Pourhanifeh MH,Hosseinzadeh A,Hemati K,Mehrzadi Sdoi
10.1016/j.virusres.2020.198108subject
Has Abstractpub_date
2020-10-02 00:00:00pages
198108eissn
0168-1702issn
1872-7492pii
S0168-1702(20)31015-7journal_volume
287pub_type
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