Clustering of haemagglutinin gene sequences of measles viruses isolated in the Gambia.

Abstract:

:Partial nucleotide sequences of the haemagglutinin (H) gene of 18 measles viruses isolated in the Gambia during 1994 and 1995 show a high degree of homology (> 98.5%) when compared with each other. These sequences form a cluster distinct from measles viruses isolated from other geographic regions and from the sequences of vaccine strains and two isolates from the Gambia from earlier years. Despite the low level of genetic heterogeneity observed, a common feature of the Gambian isolates is the presence of three nucleotide changes (at positions 7963, 8649 and 8653) not observed in isolates from other locations.

journal_name

Virus Res

journal_title

Virus research

authors

Outlaw MC,Jaye A,Whittle HC,Pringle CR

doi

10.1016/s0168-1702(96)01434-7

subject

Has Abstract

pub_date

1997-05-01 00:00:00

pages

125-31

issue

2

eissn

0168-1702

issn

1872-7492

pii

S0168-1702(96)01434-7

journal_volume

48

pub_type

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