Highly effective inhibition of Akabane virus replication by siRNA genes.

abstract：:Influenza virus rgVac1sub-P0 (H5N1) (rgVac1-P0), in which a pair of dibasic amino acid residues was introduced at the cleavage site of the HA of a reassortant of H5N2 and H7N1 viruses of duck origin, was low pathogenic in chickens. Vac1sub-P3 (H5N1) (Vac1-P3) was selected as a highly pathogenic avian influenza virus b...

journal_title：Virus research

authors： Yamamoto N,Soda K,Sakoda Y,Okamatsu M,Kida H

更新日期：2013-05-01 00:00:00

abstract：:This review describes the characterization of porcine circovirus type 2 (PCV2), the field situation of porcine circovirus-associated disease (PCVAD) and the PCV2 vaccine in Korea. PCVAD has been considered the most devastating disease in Korean livestock history since its first outbreak in 1999. Postweaning multisyste...

journal_title：Virus research

authors： Chae C

更新日期：2012-03-01 00:00:00

abstract：:Viral replication and neutralization of hepatitis C viruses (HCV) have been studied using the infectious molecular clone JFH-1. By passaging JFH-1 in hepatoma cells in the absence or presence of HCV neutralizing antibodies (nAbs), we investigated the molecular mechanisms of cell-culture adaptation and sensitivity to n...

journal_title：Virus research

authors： Song H,Ren F,Li J,Shi S,Yan L,Gao F,Li K,Zhuang H

更新日期：2012-10-01 00:00:00

abstract：:Blackberry yellow vein disease is the most important viral disease of blackberry in the United States. Experiments were conducted to characterize a new virus identified in symptomatic plants. Molecular analysis revealed a genome organization resembling Grapevine leafroll-associated virus 3, the type species of the gen...

journal_title：Virus research

authors： Thekke-Veetil T,Aboughanem-Sabanadzovic N,Keller KE,Martin RR,Sabanadzovic S,Tzanetakis IE

更新日期：2013-12-26 00:00:00

abstract：:Tobacco mosaic virus (TMV) is a positive-sense plant RNA virus which has a wide host range and a worldwide distribution. Other than a troublesome pathogen, TMV is regarded as a model system pioneering biologic research for a century. The tomato strain of TMV has been recognized to be a distinct tobamovirus as the toma...

journal_title：Virus research

authors： He M,He CQ,Ding NZ

更新日期：2012-01-01 00:00:00

abstract：:Rice false smut caused by Ustilaginoidea virens is a destructive disease in many rice-growing areas. Mycoviruses have been described in many fungal species, but there is little information regarding mycoviruses in U. virens. In this study, double-stranded (ds) RNA banding patterns were assessed in 198 wild-type isolat...

journal_title：Virus research

authors： Jiang Y,Zhang T,Luo C,Jiang D,Li G,Li Q,Hsiang T,Huang J

更新日期：2015-01-02 00:00:00

abstract：:The cis-acting replication element (CRE) in the 2C protein coding region [CRE(2C)] of enteroviruses (EV) facilitates the addition of two uridine residues (uridylylation) onto the virus-encoded protein VPg in order for it to serve as the RNA replication primer. We demonstrated that coxsackievirus B3 (CVB3) is replicati...

journal_title：Virus research

authors： Smithee S,Tracy S,Chapman NM

更新日期：2016-07-15 00:00:00

abstract：:Bats are reservoir hosts of many zoonotic viruses and identification of viruses that they carry is important. This study aimed to use high throughput screening to identify the viruses in fecal guano of Taiwanese insectivorous bats caves in order to obtain more information on bat-derived pathogenic viruses in East Asia...

journal_title：Virus research

authors： Doysabas KCC,Oba M,Furuta M,Iida K,Omatsu T,Furuya T,Okada T,Sutummaporn K,Shimoda H,Wong ML,Wu CH,Ohmori Y,Kobayashi R,Hengjan Y,Yonemitsu K,Kuwata R,Kim YK,Han SH,Sohn JH,Han SH,Suzuki K,Kimura J,Maeda K,O

更新日期：2019-01-02 00:00:00

abstract：:A disease of Rudbeckia hirta (Black-eyed Susan), characterized by severe flower deformation, was observed in Minnesota during 2010-2016. A previously undescribed virus species, named Rudbeckia flower distortion virus (RuFDV, family Caulimoviridae, genus unassigned), was determined to be the causal agent of the disease...

journal_title：Virus research

authors： Lockhart B,Mollov D,Olszewski N,Goldsmith N

更新日期：2017-09-15 00:00:00

abstract：:At present there is much interest in the cell tropism and host range of influenza viruses, especially those of the H5N1 subtype. We wished to develop a method that would enable investigation of attachment of infectious virus through the interaction of the hemagglutinin molecule and live mammalian and avian cells and t...

journal_title：Virus research

authors： Rimmelzwaan GF,Nieuwkoop NJ,de Mutsert G,Boon AC,Kuiken T,Fouchier RA,Osterhaus AD

更新日期：2007-11-01 00:00:00

abstract：:The sub-cellular location and mechanism of membrane association of NS3 and NS2-3 polypeptides of bovine viral diarrhoea virus (BVDV) have been examined. Both NS3 and NS2-3 proteins were detected in post-nuclear membrane fractions but not in cytosolic fractions of BVDV infected cells; a proportion of NS3, but not NS2-3...

journal_title：Virus research

authors： Zhang G,Flick-Smith H,McCauley JW

更新日期：2003-11-01 00:00:00

abstract：:Although a significant progress has been achieved on dsRNA mediated anti-virus strategy development, there is still no effective means to control the virulent white spot syndrome virus (WSSV). Six double-stranded RNAs specific to different essential genes of WSSV (ie1, ie3, pol (DNA polymerase), rr2 (ribonucleotide re...

journal_title：Virus research

authors： Attasart P,Kaewkhaw R,Chimwai C,Kongphom U,Namramoon O,Panyim S

更新日期：2009-10-01 00:00:00

abstract：:The structural envelope glycoprotein GP4 of European porcine reproductive and respiratory syndrome virus (PRRSV) strains contains a highly variable neutralizing epitope that is susceptible to neutralizing antibody-mediated selective pressure in vitro. In this study, it was analyzed what happens with this neutralizing ...

journal_title：Virus research

authors： Costers S,Vanhee M,Van Breedam W,Van Doorsselaere J,Geldhof M,Nauwynck HJ

更新日期：2010-12-01 00:00:00

abstract：:African horse sickness (AHS) is a devastating viral disease affecting equines and has resulted in many disastrous epizootics. To date, no successful therapeutic treatment exists for AHS, and commercially used live-attenuated vaccines have various undesirable side effects. Previous studies have shown that mice inoculat...

journal_title：Virus research

authors： Fearon SH,Dennis SJ,Hitzeroth II,Rybicki EP,Meyers AE

更新日期：2021-01-06 00:00:00

abstract：:p29, a newly identified Kaposi's sarcoma-associated herpesvirus (KSHV) protein, is the product of ORF67, the positional homolog of the conserved herpesvirus protein UL34. Like its homologues in other herpesviruses, p29 is expressed early during viral lytic cycle, and is localized on the nuclear rim. Upon chemical indu...

journal_title：Virus research

authors： Farina A,Santarelli R,Bloise R,Gonnella R,Granato M,Bei R,Modesti A,Cirone M,Bengtsson L,Angeloni A,Faggioni A

更新日期：2013-08-01 00:00:00

abstract：:Dengue is now hyper-endemic in most parts of south and southeast Asia including India. The northern India particularly national capital New Delhi witnessed major Dengue outbreaks with Dengue virus type 1 (DENV-1) as the dominant serotype since last five years. This study was initiated to decipher the complete genome i...

journal_title：Virus research

authors： Dash PK,Sharma S,Soni M,Agarwal A,Sahni AK,Parida M

更新日期：2015-01-02 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) replication and transcription activator (RTA) is necessary and sufficient for the switch from KSHV latency to lytic replication. RTA activates promoters by several mechanisms. RTA can bind to sequences in viral promoters and activate transcription. In addition, RTA intera...

journal_title：Virus research

authors： Papugani A,Coleman T,Jones C,Zhang L

更新日期：2008-01-01 00:00:00

abstract：:The identification of ligand-binding sites is often the first step in drug targeting and design. To date there are numerous computational tools available to predict ligand binding sites. These tools can guide or mitigate the need for experimental methods to identify binding sites, which often require significant resou...

journal_title：Virus research

authors： Brown JA,Espiritu MV,Abraham J,Thorpe IF

更新日期：2016-08-15 00:00:00

abstract：:We have determined the post-translational modifications of the major capsid protein, L1 of human papillomavirus (HPV) type 6b. Since this virus cannot be cultured in the laboratory to obtain sufficient material for a study, a recombinant L1 protein produced in a vaccinia virus expression system was used in this invest...

journal_title：Virus research

authors： Fang NX,Frazer IH,Zhou J,Fernando GJ

更新日期：1999-04-01 00:00:00

abstract：:We have found that an HIV-1 accessory gene product Vpr enhanced HIV-1 reproduction in U1 cells chiefly by the induction of TNF, a proinflammatory cytokine, which was also known to be an activator of HIV-1 reproduction. We have generated the functional HIV-1 accessory gene product Vpr in bacterial cells. Vpr was genera...

journal_title：Virus research

authors： Nakamura T,Suzuki H,Okamoto T,Kotani S,Atsuji Y,Tanaka T,Ito Y

更新日期：2002-12-01 00:00:00

abstract：:We here report the results of an investigation of the effect of interferon on the establishment of new infections by a retrovirus. For this study, we used an infectious but replication-incompetent retrovirus carrying a drug-resistance gene and assayed for infectivity by measuring drug-resistant colony formation. Mouse...

journal_title：Virus research

authors： Kumar R,Sen GC

更新日期：1989-08-01 00:00:00

abstract：:Herein we describe the construction of recombinant human rhinoviruses (rHRVs) encoding HIV Gag or Tat by inserting the full length tat gene or regions of the gag gene flanked by sequences encoding the HRV 2A protease cleavage site into the junction between HRV genes encoding structural (P1) and non-structural (P2) pro...

journal_title：Virus research

authors： Tomusange K,Yu W,Suhrbier A,Wijesundara D,Grubor-Bauk B,Gowans EJ

更新日期：2015-05-04 00:00:00

abstract：:A fragment of DNA from within the minimum transforming region (mtr-1) of herpes simplex virus type 1 (HSV-1) is known to raise the mutation frequency of cells. This activity has been attributed to a viral protein whose properties are largely unknown. Antiserum was raised to a synthetic peptide of a predicted amino aci...

journal_title：Virus research

authors： Das CM,Zhang S,Shillitoe EJ

更新日期：1994-11-01 00:00:00

abstract：:Herpes simplex virus glycoprotein B (HSV gB) is essential for penetration of virus into cells, for cell-to-cell spread of virus, and for cell-cell fusion. Every member of the family Herpesviridae has a gB homolog, underlining its importance. The antigenic structure of gB has been studied extensively, but little is kno...

journal_title：Virus research

authors： Norton DD,Dwyer DS,Muggeridge MI

更新日期：1998-05-01 00:00:00

abstract：:The genomic RNA of vitiviruses contains 5 open reading frames (ORF). ORF3 encodes a protein to which the function of a movement protein (MP) was assigned, based on sequence homology with other viral proteins. The aim of the research described in this paper was to gain further insight in distribution profile of the ORF...

journal_title：Virus research

authors： Haviv S,Moskovitz Y,Mawassi M

更新日期：2012-01-01 00:00:00

abstract：:The K1L protein of vaccinia virus is required for its growth in certain cell lines (RK-13 and human). The cowpox host-range protein CP77 has been shown to complement K1L function in RK-13 cells, despite a lack of homology between the two proteins except for ankyrin repeats. We investigated the role of ankyrin repeats ...

journal_title：Virus research

authors： Bradley RR,Terajima M

更新日期：2005-12-01 00:00:00

abstract：:Atlantic salmon paramyxovirus (ASPV) was isolated in 1995 from gills of farmed Atlantic salmon suffering from proliferative gill inflammation. The complete genome sequence of ASPV was determined, revealing a genome 16,968 nucleotides in length consisting of six non-overlapping genes coding for the nucleo- (N), phospho...

journal_title：Virus research

authors： Falk K,Batts WN,Kvellestad A,Kurath G,Wiik-Nielsen J,Winton JR

更新日期：2008-05-01 00:00:00

abstract：:Confocal microscopy revealed that Rice dwarf virus (RDV) initially accumulated in epithelial cells of the filter chamber of leafhopper vector Nephotettix cincticeps 2 days after acquisition access feeding on diseased plants. Subsequently, RDV accumulation progressed to the anterior midgut, and then spread to the nervo...

journal_title：Virus research

authors： Chen H,Chen Q,Omura T,Uehara-Ichiki T,Wei T

更新日期：2011-09-01 00:00:00

abstract：:Theiler's murine encephalomyelitis virus is divided into two subgroups on the basis of their different biological activities. GDVII subgroup strains cause acute and fatal encephalomyelitis in mice, while TO or DA subgroup strains cause non-fatal polioencephalomyelitis in weanling mice followed by virus persistence and...

journal_title：Virus research

authors： Ichinose-Asakura K,Taniura N,Himeda T,Nojiri M,Okuwa T,Ohara Y

更新日期：2010-02-01 00:00:00

abstract：:Infectious salmon anaemia virus (ISAV) is an orthomyxovirus causing anaemia and circulatory disease with high mortality in farmed Atlantic salmon (Salmo salar). Orthomyxoviruses are unusual as RNA viruses as they replicate in the nucleus and some viral transcripts undergo splicing. The nuclear replication necessitates...

journal_title：Virus research

authors： Ramly RB,Olsen CM,Braaen S,Rimstad E

更新日期：2013-10-01 00:00:00