Interferon-mediated inhibition of retroviral infection: use of a defective retrovirus carrying a drug-resistance gene.

abstract：:We determined the nucleotide sequence of a 3,811 base pair (bp) region of the bovine herpesvirus type-1 (BHV-1) HindIII-A fragment covering map units 0.429-0.456, which contained the HSV-1 homologues of the UL25, UL26 and UL26.5 genes. Sequence overlap was verified with previously published BHV-1 sequences, resulting ...

journal_title：Virus research

authors： Haanes EJ,Chen CC,Lowery DE

更新日期：1997-04-01 00:00:00

abstract：:To model HCV resistance to a treatment with interferon-alpha (IFN-alpha) and ribavirin, Huh7 cells, bearing HCV subgenomic replicons, were treated with these compounds for several weeks. Analysis of the cell clones, which were able to support replication of HCV RNA in the presence of high concentrations of these antiv...

journal_title：Virus research

authors： Aus dem Siepen M,Oniangue-Ndza C,Wiese M,Ross S,Roggendorf M,Viazov S

更新日期：2007-04-01 00:00:00

abstract：:Diagnostic methods allowing for rapid identification of pathogens are crucial for controlling and preventing dissemination after disease outbreaks as well as for use in surveillance programs. For arboviruses, detection of the presence of virus in their arthropod hosts is important for monitoring of viral activity and ...

journal_title：Virus research

authors： Mwaengo D,Lorenzo G,Iglesias J,Warigia M,Sang R,Bishop RP,Brun A

更新日期：2012-10-01 00:00:00

abstract：:Papillomaviruses infect keratinocytes and their reproduction is tied to differentiation of the skin. The E2 protein of papillomaviruses is a multifunctional early protein that binds specifically to the viral DNA to regulate genome transcription, replication, and segregation. All of these are nuclear events that requir...

journal_title：Virus research

authors： Bian XL,Wilson VG

更新日期：2010-06-01 00:00:00

abstract：:Purified retrovirus RD114 p30 was found to bind to the extracellular matrix proteins, fibronectin and laminin. The purified matrix proteins were immobilized onto polystyrene and the binding of p30 was quantitated using radioiodinated proteins and enzyme immunoassay (EIA). The dissociation constants were for the p30-fi...

journal_title：Virus research

authors： Salonen EM,Suni J,Vaheri A

更新日期：1984-01-01 00:00:00

abstract：:Real-time and visual tracking of viral infection is crucial for elucidating the infectious and pathogenesis mechanisms. To track the virus successfully, an efficient labeling method is necessary. In this review, we first discuss the practical labeling techniques for virus tracking in live cells. We then describe the c...

journal_title：Virus research

authors： Liu X,Ouyang T,Ouyang H,Ren L

更新日期：2017-06-02 00:00:00

abstract：:Viruses are most frequently discovered because they cause disease. To expand knowledge of plant-associated viruses beyond these narrow constraints, non-cultivated plants of the Tallgrass Prairie of the United States were systematically surveyed for evidence of viruses. This report discusses putative viruses of the fam...

journal_title：Virus research

authors： Thapa V,Melcher U,Wiley GB,Doust A,Palmer MW,Roewe K,Roe BA,Shen G,Roossinck MJ,Wang YM,Kamath N

更新日期：2012-07-01 00:00:00

abstract：:Polyomavirus-infected cells express three proteins in the early phase of the lytic cycle, the so-called tumor antigens. Two of them, large- and middle-T antigens, are also required for virus-mediated transformation of primary cells, while middle-T alone is sufficient to transform established cells in culture. Cell tra...

journal_title：Virus research

authors： Hofer U,Wehrle B,Ballmer-Hofer K

更新日期：1995-02-01 00:00:00

abstract：:Puumala (PUU) virus causes a form of hemorrhagic fever with renal syndrome (HFRS), called nephropathia epidemica (NE), in Europe. HFRS is characterized by an increased capillary permeability, which we hypothesize is caused by hyperactivation of the host immune system, especially cellular immune responses. To identify ...

journal_title：Virus research

authors： Terajima M,Van Epps HL,Li D,Leporati AM,Juhlin SE,Mustonen J,Vaheri A,Ennis FA

更新日期：2002-03-20 00:00:00

abstract：:A 50-kDa protein that binds to viral particles in solid-phase assays and that is recognized by anti-idiotypic antibodies made against anti-viral glycoproteins G1/G2 (anti-Ids) has been proposed as a receptor candidate for tomato spotted wilt tospovirus (TSWV) in its main thrips vector, Frankliniella occidentalis Perga...

journal_title：Virus research

authors： Medeiros RB,Ullman DE,Sherwood JL,German TL

更新日期：2000-04-01 00:00:00

abstract：:The encephalomyocarditis (EMC) virus-induced diabetes-like syndrome in mouse inbred strains was used as a model to study the insulin-dependent diabetes mellitus (IDDM). Our investigations were performed with two EMC virus variants, PV2 and PV7. After infection of SJL mice with 10(5) PFU of PV2 about 70% of the animals...

journal_title：Virus research

authors： Nelsen-Salz B,Zimmermann A,Wickert S,Arnold G,Botta A,Eggers HJ,Kruppenbacher JP

更新日期：1996-04-01 00:00:00

abstract：:The pathogenesis of chorioallantoic membrane (CAM) infection with herpes simplex virus 1 and 2 (HSV-1 and HSV-2) as well as chick embryo fibroblast (CEF) passaged HSV-1 was studied. It was found that HSV-2 is at least a million-fold more virulent than HSV-1 as measured by pfu/LD50 ratios for the embryo. Serial passage...

journal_title：Virus research

authors： Goodman JL,Stevens JG

更新日期：1986-08-01 00:00:00

abstract：:Sequence analyses of VP3 gene segments of Wongorr virus isolates from the Northern Territory of Australia were compared with the cognate gene segments from Picola and Paroo River viruses. Previous serological investigations had demonstrated some relationships between these viruses, however VP3 gene sequence and phylog...

journal_title：Virus research

authors： Parkes H,Gould AR

更新日期：1996-10-01 00:00:00

abstract：:Hamster polyomavirus (HaPyV) major capsid protein VP1 based chimeric virus-like particles (VLPs) carrying model GP33 CTL epitope derived from Lymphocytic choriomeningitis virus (LCMV) were generated in yeast and examined for their capability to induce CTL response in mice. Chimeric VP1-GP33 VLPs were effectively proce...

journal_title：Virus research

authors： Mazeike E,Gedvilaite A,Blohm U

更新日期：2012-01-01 00:00:00

abstract：:The goal of this review is to summarize recently published epidemiological information that contribute to understanding the natural history of cervical and human papillomavirus (HPV) infection and their associated lesions among human immunodeficiency virus (HIV) infected women and men. HIV-positive women and men are m...

journal_title：Virus research

authors： de Sanjosé S,Palefsky J

更新日期：2002-11-01 00:00:00

abstract：:The nucleotide sequence of the matrix gene (M) of a recently identified morbillivirus, phocid distemper virus (PDV), was determined and the amino acid composition deduced. The M gene of PDV shared many characteristics with the corresponding gene in other morbilliviruses. The nucleotide homology with the closely relate...

journal_title：Virus research

authors： Sharma B,Norrby E,Blixenkrone-Möller M,Kövamees J

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:This paper aims to explore the effect of four virus inactivation methods on the rapid detection results of COVID-19 nucleic acid. METHODS:Collected samples of nasopharyngeal swabs from 2 patients diagnosed with COVID-19 at the First People's Hospital of Zhaoqing City, each of sample was divided into 5 groups...

journal_title：Virus research

authors： Wang Y,Song W,Zhao Z,Chen P,Liu J,Li C

更新日期：2020-08-01 00:00:00

abstract：:For the production of viral genomic RNA, HIV-1 is dependent on an early viral protein, Tat, which is required for high-level transcription. The quantity of viral RNA detectable in blood of HIV-1 infected individuals varies dramatically, and a factor involved could be the efficiency of Tat protein variants to stimulate...

journal_title：Virus research

authors： van der Kuyl AC,Vink M,Zorgdrager F,Bakker M,Wymant C,Hall M,Gall A,Blanquart F,Berkhout B,Fraser C,Cornelissen M,BEEHIVE Collaboration.

更新日期：2018-05-02 00:00:00

abstract：:For detection of spring viremia of carp virus (SVCV) DNA probes have been constructed using the reverse transcription-polymerase chain reaction (RT-PCR) amplification technique and cDNA cloning in plasmid and phage vectors. The specific primers for amplification of SVCV M and G genes were chosen and synthesized. Studi...

journal_title：Virus research

authors： Oreshkova SF,Shchelkunov IS,Tikunova NV,Shchelkunova TI,Puzyrev AT,Ilyichev AA

更新日期：1999-09-01 00:00:00

abstract：:Recombinant clones containing all or portions of the bovine papillomavirus (BPV) upstream regulatory region (URR) were constructed. When analyzed by polyacrylamide gel electrophoresis, the cloned URR sequences exhibited electrophoretic properties characteristic of DNA containing bend sites. Two distinct bend centers w...

journal_title：Virus research

authors： Wilson VG

更新日期：1989-05-01 00:00:00

abstract：:The fusion (F) proteins of 10 strains of bovine respiratory syncytial virus (BRSV) were compared by radioimmunoprecipitation with fractionation on SDS-polyacrylamide gels. Two different molecular weights (15 kDa and 20 kDa) of the F2 proteins were demonstrated among the BRSV strains tested. To delineate the molecular ...

journal_title：Virus research

authors： Pastey MK,Samal SK

更新日期：1993-08-01 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) in humans is caused mainly by Enterovirus 71(EV71) and Coxsackievirus A16 (CVA16). EV71 is associated with severe HFMD cases but not CVA16. Use of IgM-capture enzyme-linked immunosorbent assay (ELISA) is important for the early diagnosis of EV71 infection, but cross-reactivity of th...

journal_title：Virus research

authors： Wang C,You A,Tian X,Zhao M,Chen Y,Lin T,Zheng J,Xiao M,Zhang Y,Kuang L,Zhou Z,Zhu B

更新日期：2013-09-01 00:00:00

abstract：:The human T-lymphotropic virus type-1 (HTLV-1) is the causative agent of a chronic progressive myelopathy (TSP/HAM) in which lesions of the central nervous system (CNS) are associated with infiltration of HTLV-1-infected T-cells. In a model that mimics the interaction between glial and T-cells, we show that transient ...

journal_title：Virus research

authors： Akaoka H,Szymocha R,Beurton-Marduel P,Bernard A,Belin MF,Giraudon P

更新日期：2001-10-30 00:00:00

abstract：:The glycoprotein (G) is the only surface protein of the lyssavirus particle and the only viral product known to be capable of eliciting the production of neutralizing antibodies. In this study, the isolation of escape mutants resistant to monoclonal antibody (Mab) neutralization was attempted by a selection strategy e...

journal_title：Virus research

authors： Fallahi F,Wandeler AI,Nadin-Davis SA

更新日期：2016-07-15 00:00:00

abstract：:From the sera of patients with advanced cancer, a novel factor called SDF (serum-derived factor) was partially purified. SDF was shown to stimulate transcription from the long terminal repeat (LTR) of human immunodeficiency virus type 1 (HIV-1) by transient CAT assay. It did not stimulate gene expression of various co...

journal_title：Virus research

authors： Ogiwara H,Nakamura T,Baba S,Okamoto T

更新日期：1993-09-01 00:00:00

abstract：:The subcellular distribution of influenza polymerase PA subunit has been studied using a SV40-recombinant virus (SVPA76), which allows the expression and accumulation of this protein in COS-1 cells. In contrast to the complete nuclear localization observed for the PA subunit several hours after influenza virus infecti...

journal_title：Virus research

authors： Nieto A,de la Luna S,Bárcena J,Portela A,Valcárcel J,Melero JA,Ortín J

更新日期：1992-06-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is a major cause of respiratory tract infections in children, elderly and immunocompromised hosts, for which no vaccine or treatment are currently available. Oxidative stress and inflammatory responses represent important pathogenic mechanism(s) of hMPV infection. Here, we explored the pot...

journal_title：Virus research

authors： Komaravelli N,Kelley JP,Garofalo MP,Wu H,Casola A,Kolli D

更新日期：2015-03-16 00:00:00

abstract：:Plant viruses express RNA silencing suppressor (RSS) proteins to counteract plant defence mechanisms. Here, we describe a method to assess the RSS activity based on an alfalfa mosaic virus (AMV) RNA 3 expression vector and transgenic Nicotiana tabacum plants that express the P1 and P2 subunits of the AMV replicase (P1...

journal_title：Virus research

authors： Martínez-Pérez M,Navarro JA,Pallás V,Sánchez-Navarro JA

更新日期：2019-10-15 00:00:00

abstract：:When the hepatitis B virus (HBV) enters target cells, there are complex trans-regulatory mechanisms involved in the interactions between the virus and the target cells. In the present study, a new gene screened from the hepatoblastoma cell line HepG2 using suppression subtractive hybridization, referred to as lncRNA H...

journal_title：Virus research

authors： Lun YZ,Pan ZP,Liu SA,Sun J,Han M,Liu B,Dong W,Pan LH,Cheng J

更新日期：2020-10-02 00:00:00

abstract：:Transcription of human immunodeficiency virus (HIV-1) is activated by viral Tat protein which regulates HIV-long terminal repeat (LTR) transcription and elongation. HIV-1 Tat protein is a substrate for the deacetylase activity of sirtuin 1 (SIRT1). Here we investigate the signaling pathway involved in Tat-induced HIV-...

journal_title：Virus research

authors： Zhang HS,Wu MR

更新日期：2009-12-01 00:00:00