Abstract:
:Atlantic salmon paramyxovirus (ASPV) was isolated in 1995 from gills of farmed Atlantic salmon suffering from proliferative gill inflammation. The complete genome sequence of ASPV was determined, revealing a genome 16,968 nucleotides in length consisting of six non-overlapping genes coding for the nucleo- (N), phospho- (P), matrix- (M), fusion- (F), haemagglutinin-neuraminidase- (HN) and large polymerase (L) proteins in the order 3'-N-P-M-F-HN-L-5'. The various conserved features related to virus replication found in most paramyxoviruses were also found in ASPV. These include: conserved and complementary leader and trailer sequences, tri-nucleotide intergenic regions and highly conserved transcription start and stop signal sequences. The P gene expression strategy of ASPV was like that of the respiro-, morbilli- and henipaviruses, which express the P and C proteins from the primary transcript and edit a portion of the mRNA to encode V and W proteins. Sequence similarities among various features related to virus replication, pairwise comparisons of all deduced ASPV protein sequences with homologous regions from other members of the family Paramyxoviridae, and phylogenetic analyses of these amino acid sequences suggested that ASPV was a novel member of the sub-family Paramyxovirinae, most closely related to the respiroviruses.
journal_name
Virus Resjournal_title
Virus researchauthors
Falk K,Batts WN,Kvellestad A,Kurath G,Wiik-Nielsen J,Winton JRdoi
10.1016/j.virusres.2008.01.006subject
Has Abstractpub_date
2008-05-01 00:00:00pages
218-27issue
2eissn
0168-1702issn
1872-7492pii
S0168-1702(08)00029-4journal_volume
133pub_type
杂志文章相关文献
VIRUS RESEARCH文献大全abstract::Cucurbit chlorotic yellows virus (CCYV) is a new member of the genus Crinivirus (family Closteroviridae) with a bi-partite genome. CCYV RNA 1-encoded p22 has recently been reported to be a weak local suppressor of RNA silencing for which an interaction with cucumber SKP1LB1 through an F-box-like motif was demonstrated...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2020.197887
更新日期:2020-04-02 00:00:00
abstract::The nucleotide sequences of the nucleoprotein (NP) genes of fowl plague virus (FPV) and of a temperature-sensitive (ts) mutant (ts81) derived therefrom have been determined. The ts81-NP nucleotide sequence possesses a single nucleotide substitution in comparison to the wild type. This causes an amino acid exchange at ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(89)90058-0
更新日期:1989-02-01 00:00:00
abstract::Phylogenetic analysis has been extensively used as a tool for the reconstruction of epidemiological relations for research or for forensic purposes. It was our objective to assess the sensitivity of different phylogenetic methods and various phylogenetic programs to reconstruct epidemiological links among HIV-1 infect...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2012.03.002
更新日期:2012-06-01 00:00:00
abstract::C167, a mutant derived from the XJC13 strain of Junin virus, is highly attenuated in its pathogenic properties for newborn mice. Whereas 10(2).PFU of XJC13 injected intracerebrally killed 100% of two-day-old mice, the mutant showed no detectable lethality. Survival of mice infected with C167 was associated with a redu...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(89)90074-9
更新日期:1989-08-01 00:00:00
abstract::The table grape variety "Waltham Cross" was infected with Leafroll and Shiraz Disease. To reveal specific viruses that are associated with the diseased plants, we used an RT-PCR-based strategy to determine partial genome sequences of these viruses. Upon cloning and sequencing of the RT-PCR products, we detected seven ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2006.10.014
更新日期:2007-03-01 00:00:00
abstract::The main cellular target for African swine fever virus (ASFV) is the porcine macrophage. However, existing data about the early phases of infection were previously characterized in non-leukocyte cells such as Vero cells. Here, we report that ASFV enters the natural host cell using dynamin-dependent and clathrin-mediat...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2015.01.022
更新日期:2015-03-16 00:00:00
abstract::Marek's disease virus (MDV) is an oncogenic herpesvirus that causes a disease in chickens characterized by tumor formation and immunosuppression. In this paper, we identified differentially expressed proteins in the bursa of Fabricius of chickens infected with the highly virulent MDV strain RB1B, using two-dimensional...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2010.08.010
更新日期:2010-11-01 00:00:00
abstract::Three dendrimeric peptides were synthesized in order to evaluate their immunogenicity and their potential protection against classical swine fever virus (CSFV) in domestic pigs. Construct 1, an optimized version of a previously used dendrimer, had four copies of a B-cell epitope derived from CSFV E2 glycoprotein conne...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2017.05.020
更新日期:2017-06-15 00:00:00
abstract::Mixed viral infections can induce different changes in symptom development, genome accumulation and tissue tropism. These issues were investigated for two phloem-limited begomoviruses, Abutilon mosaic virus (AbMV) and Tomato yellow leaf curl Sardinia virus (TYLCSV) in Nicotiana benthamiana plants doubly infected by ei...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2011.07.021
更新日期:2011-11-01 00:00:00
abstract::Infectious spleen and kidney necrosis virus (ISKNV) is a typical species of the genus Megalocytivirus in the family Iridoviridae. However, until recently, no suitable piscine cell line is stably susceptible to ISKNV. Here, a continuous cell culture derived from the mandarin fish fry (MFF-1) was developed and has been ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2008.04.004
更新日期:2008-08-01 00:00:00
abstract::Infectious pancreatic necrosis virus (IPNV), a Birnaviridae with a double-stranded RNA genome of two segments, is an important aquatic pathogen. Previous characterizations of the RNA and polypeptide patterns of different IPNV isolates have uncovered a wide variety of electropherotypes. We used RNA fingerprinting analy...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(95)00035-o
更新日期:1995-08-01 00:00:00
abstract::Human torovirus (HTV) and Breda virus (BRV), members of the genus torovirus in the family Coronaviridae, are established infectious agents of humans and cattle, respectively. The hemagglutinin-esterase (HE) gene of Breda virus serotype 2 (BRV-2) has been identified and the nucleotide sequence for BRV serotype 1 (BRV-1...
journal_title:Virus research
pub_type: 杂志文章,收录出版
doi:10.1016/s0168-1702(99)00088-x
更新日期:1999-11-01 00:00:00
abstract::Central nervous system (CNS) infection with herpes simplex virus (HSV)-1 triggers neuroinflammatory responses leading to peripheral immune cell infiltration into the brain. Previous in vitro studies from our laboratory, using primary human brain cells, implicated microglia as the cellular source of infection-induced c...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2006.03.009
更新日期:2006-10-01 00:00:00
abstract::A wide use of inhibitors of influenza virus neuraminidase (NAIs) to control influenza in humans demands a better understanding of the mechanisms involved in the resistance emergence. In vitro studies demonstrate that both neuraminidase (NA) and hemagglutinin (HA) influence virus susceptibility to NAIs. Drug resistance...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2004.02.034
更新日期:2004-07-01 00:00:00
abstract::Tick-borne encephalitis (TBE) is a serious human neurological disease caused by TBE virus (TBEV). However, the mechanisms of TBEV-caused pathogenesis remain unclear. The endoplasmic reticulum (ER) stress response, also defined as the unfolded protein response (UPR), is an important conserved molecular signaling pathwa...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2013.10.012
更新日期:2013-12-26 00:00:00
abstract::The effect of mild heat shock on the replication of human cytomegalovirus (HCMV) was studied in human embryo fibroblasts. Treatment of cell cultures at 44 degrees C for 10 min just before infection or at 24 h post infection (p.i.) shortened HCMV eclipse period and enhanced viral replication, while heat shock performed...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(86)90070-5
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:HTLV-2 infections are almost always asymptomatic, and diseases associated with the infection are rarely reported. Little information is available on the relationship between HTLV-2 proviral load and gender or expression of disease, especially among patients with HIV-1 co-infection. METHODS:We studied 77 HTL...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2008.01.015
更新日期:2008-07-01 00:00:00
abstract::p29, a newly identified Kaposi's sarcoma-associated herpesvirus (KSHV) protein, is the product of ORF67, the positional homolog of the conserved herpesvirus protein UL34. Like its homologues in other herpesviruses, p29 is expressed early during viral lytic cycle, and is localized on the nuclear rim. Upon chemical indu...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2013.04.001
更新日期:2013-08-01 00:00:00
abstract::The entire genome of a mid-Atlantic raccoon strain rabies virus (RRV) isolated in Canada was sequenced; this is the second North American wildlife rabies virus isolate to be fully characterized. The overall organization and length of the genome was similar to that of other lyssaviruses. The nucleotide sequence identit...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2008.04.029
更新日期:2008-09-01 00:00:00
abstract::This paper summarizes the progress in the search for hantaviruses and hantavirus infections in Africa. After having collected molecular evidence of an indigenous African hantavirus in 2006, an intensive investigation for new hantaviruses has been started in small mammals. Various novel hantaviruses have been molecular...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2013.12.039
更新日期:2014-07-17 00:00:00
abstract::Almost all viruses can be neutralized by antibodies. However, there is some controversy about antibody-mediated neutralization of African swine fever virus (ASFV) with sera from convalescent pigs and about the protective relevance of antibodies in experimentally vaccinated pigs. At present, there is no vaccine availab...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2012.10.012
更新日期:2013-04-01 00:00:00
abstract::The effect of three lysosomotropic compounds, chloroquine, monensin and NH4Cl, on the replication of foot-and-mouth disease virus (FMDV) type A12 was studied. Viral replication was almost totally inhibited by 0.5 mM chloroquine, 50 microM monensin, or 25 mM NH4Cl. Monensin and NH4Cl affected replication when added eit...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(87)90032-3
更新日期:1987-05-01 00:00:00
abstract::Serological parameters intend to describe antibody response to influenza vaccine in a population. However, there is uncertainty about the mathematical appropriateness and the biological or clinical meaning of conventionally used parameters. Theoretical considerations and exploration of a data-set of 16 studies with an...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2004.02.024
更新日期:2004-07-01 00:00:00
abstract::Satellite RNAs (satRNAs) and viroids belong to the group called subviral agents and are the smallest pathogens of plants. In general, small satRNAs and viroids are 300-400 nt in size and do not encode any functional proteins; they are thus regarded as so-called long noncoding RNAs (lncRNAs). These lncRNAs are receivin...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2015.06.016
更新日期:2016-01-02 00:00:00
abstract::Adult T cell leukemia/lymphoma (ATL) is a highly aggressive CD4+/CD25+ T-cell malignancy caused by human T cell lymphotropic virus type 1 (HTLV-1). Previous studies in the MET-1 cell/NOD/SCID mouse model of ATL demonstrated that MET-1 cells are very susceptible to measles virus (MV) oncolytic therapy. To further evalu...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2014.05.025
更新日期:2014-08-30 00:00:00
abstract::The attenuated equine infectious anemia virus (EIAV) vaccine was the first attenuated lentivirus vaccine to be used in a large-scale application and has been used to successfully control the spread of equine infectious anemia (EIA) in China. To better understand the potential role of cytokines in the pathogenesis of E...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2011.06.028
更新日期:2011-09-01 00:00:00
abstract::Acute hemorrhagic conjunctivitis (AHC) is a self-limiting viral infection of the eyes but having epidemic potential. In winter 2004-2005, an outbreak of acute hemorrhagic conjunctivitis (AHC) occurred in Islamabad, Pakistan. The etiological agent was confirmed as coxsackievirus A24 variant (CA24v) by virus isolation a...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2008.06.011
更新日期:2008-10-01 00:00:00
abstract::Viruses are strict intracellular pathogens that require the cellular environment to complete a successful infection. Among them, African swine fever virus (ASFV) is an evolutionary ancient DNA virus, endemic in Africa, which is nowadays causing an emergent disease in Europe with a potential high economic impact in the...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2015.05.026
更新日期:2015-11-02 00:00:00
abstract::Mosquito-borne alphaviruses are disseminated globally and cause febrile illness in humans and animals. Since the prevalence and diversity of alphaviruses has not been previously investigated in Zambia, reverse transcription PCR was employed as a broad-spectrum approach for the detection of alphaviruses in mosquitoes. ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2018.04.005
更新日期:2018-05-02 00:00:00
abstract::This study reports the detection by RT-PCR and molecular characterization of partial RdRp gene of picobirnavirus (PBV) dsRNA in fecal samples (n = 100) from a meat sheep flock in southern Brazil. The analysis of the results allowed the identification of two important characteristics of PBV infection. The first was the...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2018.06.016
更新日期:2018-08-15 00:00:00