Abstract:
:The effect of mild heat shock on the replication of human cytomegalovirus (HCMV) was studied in human embryo fibroblasts. Treatment of cell cultures at 44 degrees C for 10 min just before infection or at 24 h post infection (p.i.) shortened HCMV eclipse period and enhanced viral replication, while heat shock performed at 48 h p.i. had no effect on the HCMV replication cycle. Study of HCMV-induced early and late antigens confirmed that the cellular response to heat shock influences HCMV replication in the early stage of the viral replication cycle.
journal_name
Virus Resjournal_title
Virus researchauthors
Zerbini M,Musiani M,La Placa Mdoi
10.1016/0168-1702(86)90070-5subject
Has Abstractpub_date
1986-12-01 00:00:00pages
211-6issue
3eissn
0168-1702issn
1872-7492pii
0168-1702(86)90070-5journal_volume
6pub_type
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