Phylogenetic analysis of segment 10 from African horsesickness virus and cognate genes from other orbiviruses.

abstract：:The positive sense genomes of members of the genus Flavivirus in the family Flaviviridae are ∼ 11 kb in length and have a 5' type I cap but no 3' poly-A. The 3' and 5' terminal regions contain short conserved sequences that are proposed to be repeated remnants of an ancient sequence. However, the functions of most of ...

journal_title：Virus research

authors： Brinton MA,Basu M

更新日期：2015-08-03 00:00:00

abstract：:Porcine epidemic diarrhea virus (PEDV), a member of the genus Alphacoronavirus, is a causative agent of porcine enteric disease characterized by acute watery diarrhea and dehydration in sucking piglet. Similar to other coronaviruses, PEDV spike protein mediates its cell entry by binding to cellular receptors and induc...

journal_title：Virus research

authors： Park JE,Cruz DJ,Shin HJ

更新日期：2014-10-13 00:00:00

abstract：:We have rescued a transfectant influenza virus, NA/TAIL(-), whose neuraminidase (NA) protein lacks the predicted cytoplasmic tail. The virus was attenuated (one log10 reduction) both in tissue culture and in mouse lungs. Attenuation correlated with a 50% reduction of the level of NA in infected cells and levels of inc...

journal_title：Virus research

authors： García-Sastre A,Palese P

更新日期：1995-06-01 00:00:00

abstract：:Friesian calves were infected with one of three isolates of bovine viral diarrhoea virus (BVDV) and used to establish parameters for an in vitro model of BVDV-reactive T-cell responses in cattle. The study assessed virus clearance, seroconversion, maturation of lymphoproliferative responses (both during and following ...

journal_title：Virus research

authors： Collen T,Morrison WI

更新日期：2000-03-01 00:00:00

abstract：:The BKRF2, BKRF3 and BKRF4 genes of Epstein-Barr virus (EBV) are located close together in the viral genome, which encode glycoprotein L, uracil-DNA glycosylase and a tegument protein, respectively. Here, we demonstrate that the BKRF2 gene behaves as a true-late lytic gene, whereas the BKRF3 and BKRF4 genes belong to ...

journal_title：Virus research

authors： Chen LW,Hung CH,Wang SS,Yen JB,Liu AC,Hung YH,Chang PJ

更新日期：2018-09-02 00:00:00

abstract：:Swine influenza virus (SIV) is not only an important respiratory pathogen in pigs but also a threat to human health. The pandemic influenza A(H1N1)pdm09 virus likely originated in swine through reassortment between a North American triple reassortant and Eurasian avian-like SIV. The North American triple reassortant v...

journal_title：Virus research

authors： Said A,Lange E,Beer M,Damiani A,Osterrieder N

更新日期：2013-05-01 00:00:00

abstract：:An insect High-Five cell line was generated constitutively and stably expressing the VP2 protein of rotavirus RF strain leading to the formation of core-like particles. The integration of the VP2 gene was confirmed by PCR, Real-time PCR and Southern blot, and the protein expression was confirmed by Western blot and im...

journal_title：Virus research

authors： Shoja Z,Tagliamonte M,Jalilvand S,Mokhtari-Azad T,Hamkar R,Shahmahmoodi S,Rezaei F,Tornesello M,Buonaguro FM,Buonaguro L,Nategh R

更新日期：2013-03-01 00:00:00

abstract：:The compound LPRP-Et-97543 was isolated from Liriope platyphylla roots and was observed to have potential anti-viral effects in HepG2.2.15 cells against hepatitis B virus (HBV). The antiviral mode was further clarified, and the HBV-transfected Huh7 cells were used as the platform. During viral gene expression, LPRP-Et...

journal_title：Virus research

authors： Huang TJ,Tsai YC,Chiang SY,Wang GJ,Kuo YC,Chang YC,Wu YY,Wu YC

更新日期：2014-11-04 00:00:00

abstract：:Mammalian orthoreovirus (MRV) is the type species of the genus Orthoreovirus and causes a range of significant respiratory, nervous or enteric diseases in humans and animals. In 2016 a farmed white-tailed deer (Odocoileus virginianus) fawn became ill, displaying clinical signs of lethargy, dehydration, and profuse fou...

journal_title：Virus research

authors： Ahasan MS,Subramaniam K,Sayler KA,Loeb JC,Popov VL,Lednicky JA,Wisely SM,Campos Krauer JM,Waltzek TB

更新日期：2019-09-01 00:00:00

abstract：:To investigate the evolutionary origins of proteins encoded by the Poxviridae family of viruses, we examined all poxvirus protein coding genes using a method of characterizing and visualizing the similarity between these proteins and taxonomic subsets of proteins in GenBank. Our analysis divides poxvirus proteins into...

journal_title：Virus research

authors： Odom MR,Hendrickson RC,Lefkowitz EJ

更新日期：2009-09-01 00:00:00

abstract：:Almost all viruses can be neutralized by antibodies. However, there is some controversy about antibody-mediated neutralization of African swine fever virus (ASFV) with sera from convalescent pigs and about the protective relevance of antibodies in experimentally vaccinated pigs. At present, there is no vaccine availab...

journal_title：Virus research

authors： Escribano JM,Galindo I,Alonso C

更新日期：2013-04-01 00:00:00

abstract：:Confocal microscopy revealed that Rice dwarf virus (RDV) initially accumulated in epithelial cells of the filter chamber of leafhopper vector Nephotettix cincticeps 2 days after acquisition access feeding on diseased plants. Subsequently, RDV accumulation progressed to the anterior midgut, and then spread to the nervo...

journal_title：Virus research

authors： Chen H,Chen Q,Omura T,Uehara-Ichiki T,Wei T

更新日期：2011-09-01 00:00:00

abstract：:The mammalian reoviruses possess a genome composed of 10 double stranded RNA segments. The serotype 1 strain Lang M1 segment was sequenced and compared to the published type 3 sequence. Both segments were 2304 base-pairs long coding for the mu 2 protein predicted to be 736 amino acids long. The sequences were highly c...

journal_title：Virus research

authors： Zou S,Brown EG

更新日期：1992-02-01 00:00:00

abstract：:Hepatitis D virus (HDV) is the smallest animal infecting RNA virus with unique features distinguishing it from other Hepatitis viruses. Codon usage variation is considered as an indicator of the forces shaping genome evolution. RSCU (relative synonymous codon usage) values, nucleotide contents, ENC (effective number o...

journal_title：Virus research

authors： Bishal AK,Mukherjee R,Chakraborty C

更新日期：2013-05-01 00:00:00

abstract：:Vaccine formulation can influence cytokine and disease patterns in mice following respiratory syncytial virus (RSV) challenge. The influence of different live and killed dual-vaccine combinations on subsequent immune responses was investigated. BALB/c mice received either killed followed by killed (KV/KV), killed foll...

journal_title：Virus research

authors： Tang YW

更新日期：2004-01-01 00:00:00

abstract：:Transposable elements are valuable for somatic and germ-line transformation. However, long interspersed nuclear elements (LINEs) have not been used because of poor information on the transposition mechanism. We have developed a novel gene delivery system combining baculovirus AcNPV and two silkworm LINEs, SART1 and R1...

journal_title：Virus research

authors： Kawashima T,Osanai M,Futahashi R,Kojima T,Fujiwara H

更新日期：2007-07-01 00:00:00

abstract：:Following viral infection, the host responds by mounting a robust anti-viral response with the aim of creating an unfavorable environment for viral replication. As a countermeasure, viruses have elaborated mechanisms to subvert the host response in order to maintain viral protein synthesis and production. In the last ...

journal_title：Virus research

authors： Valiente-Echeverría F,Melnychuk L,Mouland AJ

更新日期：2012-11-01 00:00:00

abstract：:C167, a mutant derived from the XJC13 strain of Junin virus, is highly attenuated in its pathogenic properties for newborn mice. Whereas 10(2).PFU of XJC13 injected intracerebrally killed 100% of two-day-old mice, the mutant showed no detectable lethality. Survival of mice infected with C167 was associated with a redu...

journal_title：Virus research

authors： Scolaro LA,Mersich SE,Damonte EB

更新日期：1989-08-01 00:00:00

abstract：:The Sindbis viral expression system enables the rapid production of high levels of recombinant protein in mammalian cells; however, this expression is typically limited to transient production due to the cytotoxicity of the virus. Limiting the lethality inherent in the Sindbis virus vector in order to enable long term...

journal_title：Virus research

authors： Nivitchanyong T,Tsai YC,Betenbaugh MJ,Oyler GA

更新日期：2009-04-01 00:00:00

abstract：:The ultrastructure of the equine morbillivirus (EMV) which was implicated in the death of one human and fourteen horses in Queensland, Australia during September 1994 and a 36 year old man from Queensland in October 1995 is described. The ultrastructure of the virus and the intracellular virus-specific structures are ...

journal_title：Virus research

authors： Hyatt AD,Selleck PW

更新日期：1996-07-01 00:00:00

abstract：:Epithelial cells are the major in vivo target cells for porcine circovirus type 2 (PCV2). Although these cells are used for most studies of PCV2 gene expression and, little is known on PCV2 entry, attachment and internalization, in epithelial cells. PCV2 attachment to epithelial cells occurred rapidly and in a time-de...

journal_title：Virus research

authors： Misinzo G,Delputte PL,Lefebvre DJ,Nauwynck HJ

更新日期：2009-01-01 00:00:00

abstract：:To model HCV resistance to a treatment with interferon-alpha (IFN-alpha) and ribavirin, Huh7 cells, bearing HCV subgenomic replicons, were treated with these compounds for several weeks. Analysis of the cell clones, which were able to support replication of HCV RNA in the presence of high concentrations of these antiv...

journal_title：Virus research

authors： Aus dem Siepen M,Oniangue-Ndza C,Wiese M,Ross S,Roggendorf M,Viazov S

更新日期：2007-04-01 00:00:00

abstract：:In mice Theiler's murine encephalomyelitis virus (TMEV) persists in macrophages that eventually undergo apoptosis. TMEV infection of macrophages in culture induces apoptosis through the intrinsic pathway, restricting virus yields. We show that inhibition of TMEV-induced apoptosis leads to phosphorylation of receptor i...

journal_title：Virus research

authors： Son KN,Lipton HL

更新日期：2015-01-02 00:00:00

abstract：:Rice false smut caused by Ustilaginoidea virens is a destructive disease in many rice-growing areas. Mycoviruses have been described in many fungal species, but there is little information regarding mycoviruses in U. virens. In this study, double-stranded (ds) RNA banding patterns were assessed in 198 wild-type isolat...

journal_title：Virus research

authors： Jiang Y,Zhang T,Luo C,Jiang D,Li G,Li Q,Hsiang T,Huang J

更新日期：2015-01-02 00:00:00

abstract：:Adult T cell leukemia/lymphoma (ATL) is a highly aggressive CD4+/CD25+ T-cell malignancy caused by human T cell lymphotropic virus type 1 (HTLV-1). Previous studies in the MET-1 cell/NOD/SCID mouse model of ATL demonstrated that MET-1 cells are very susceptible to measles virus (MV) oncolytic therapy. To further evalu...

journal_title：Virus research

authors： M Parrula MC,Fernandez SA,Landes K,Huey D,Lairmore M,Niewiesk S

更新日期：2014-08-30 00:00:00

abstract：:Nineteen distinct measles virus (MV) strains associated with nine different genotypes were identified in five Australian states (Victoria, New South Wales, Queensland, Northern Territory and Western Australia) between 1999 and 2001. One of the strains identified is likely to represent a new genotype within the clade D...

journal_title：Virus research

authors： Chibo D,Riddell M,Catton M,Lyon M,Lum G,Birch C

更新日期：2003-02-01 00:00:00

abstract：:The complete nucleotide sequence has been determined for the S RNA of Aino virus, a member of the Simbu serogroup (Bunyavirus genus, family Bunyaviridae). The S RNA is 850 nucleotides long (2.76 X 10(5) daltons) and in the viral complementary sequence has a short 5' non-coding region of 34 nucleotides and a more exten...

journal_title：Virus research

authors： Akashi H,Gay M,Ihara T,Bishop DH

更新日期：1984-01-01 00:00:00

abstract：:Tick-borne encephalitis (TBE) is a serious human neurological disease caused by TBE virus (TBEV). However, the mechanisms of TBEV-caused pathogenesis remain unclear. The endoplasmic reticulum (ER) stress response, also defined as the unfolded protein response (UPR), is an important conserved molecular signaling pathwa...

journal_title：Virus research

authors： Yu C,Achazi K,Niedrig M

更新日期：2013-12-26 00:00:00

abstract：:Citrus psorosis (CPsV) and Mirafiori lettuce big-vein virus (MiLBVV) belong to the family Ophioviridae, plant viruses with filamentous nucleocapsids and segmented genomes of negative polarity, causing the worldwide distributed citrus psorosis and lettuce big-vein diseases, respectively. To gain insight into the replic...

journal_title：Virus research

authors： Peña EJ,Robles Luna G,Zanek MC,Borniego MB,Reyes CA,Heinlein M,García ML

更新日期：2012-12-01 00:00:00

abstract：:Species members of the genus Parapoxvirus (PPV) within the family Poxviridae cause contagious pustular dermatitis in small ruminants (Orf virus, ORFV) and mostly mild localized inflammation in cattle (bovine papular stomatitis virus, BPSV and pseudocowpox virus, PCPV). All PPVs are known to be zoonotic, leading to cir...

journal_title：Virus research

authors： Friederichs S,Krebs S,Blum H,Wolf E,Lang H,von Buttlar H,Büttner M

更新日期：2014-03-06 00:00:00