Abstract:
:The mammalian reoviruses possess a genome composed of 10 double stranded RNA segments. The serotype 1 strain Lang M1 segment was sequenced and compared to the published type 3 sequence. Both segments were 2304 base-pairs long coding for the mu 2 protein predicted to be 736 amino acids long. The sequences were highly conserved with 97.2% conservation of nucleotide sequence and 98.6% conservation of amino acid sequence. The M1 segments of serotypes 1 and 3 have recently diverged as indicated by the distribution of variation with respect to codon positions. The conservation of amino acid sequence indicated that the mu 2 protein has a relatively high functional density.
journal_name
Virus Resjournal_title
Virus researchauthors
Zou S,Brown EGdoi
10.1016/0168-1702(92)90042-8subject
Has Abstractpub_date
1992-02-01 00:00:00pages
159-64issue
2eissn
0168-1702issn
1872-7492pii
0168-1702(92)90042-8journal_volume
22pub_type
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