Abstract:
:Despite the fact that cells infected with wild type vaccinia virus synthesize viral DNA and assemble progeny virus particles within the cytoplasm, the host cell nucleus is required for a productive infection. Recent evidence suggests that vaccinia virus selectively recruits components from the host cell nucleus into the cytoplasm for use by the developing virus. One of these components is the largest subunit of the cellular RNA polymerase II (Pol II).
journal_name
Virus Resjournal_title
Virus researchauthors
Moyer RWdoi
10.1016/0168-1702(87)90014-1subject
Has Abstractpub_date
1987-09-01 00:00:00pages
173-91issue
3eissn
0168-1702issn
1872-7492pii
0168-1702(87)90014-1journal_volume
8pub_type
杂志文章,评审相关文献
VIRUS RESEARCH文献大全abstract::Analysis of complete polyprotein-encoding sequences of the two most prevalent genotypes of hepatitis C virus (HCV-1a and HCV-1b) revealed evidence of abundant, slightly deleterious nonsynonymous variants subject to ongoing purifying selection. In the case of both HCV-1a and HCV-1b, the NS3 protein demonstrated a high ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2009.11.001
更新日期:2010-02-01 00:00:00
abstract::JCPyV and BKPyV are common human polyomaviruses that cause lifelong asymptomatic persistent infections in their hosts. In immunosuppressed individuals, increased replication of JCPyV and BKPyV cause significant disease. JCPyV causes a fatal and rapidly progressing demyelinating disease known as progressive multifocal ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2014.06.008
更新日期:2014-08-30 00:00:00
abstract::The full genomic nucleotide sequence of a previously identified genotype 3 hepatitis E virus (HEV), strain SAAS-JDY5, was obtained using RT-PCR and rapid amplification of cDNA ends (RACE). The genome consisted of 7225 nucleotides, excluding a poly-A tail at the 3' terminus, and contained three open reading frames (ORF...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2009.04.009
更新日期:2009-09-01 00:00:00
abstract::Avian orthoreoviruses cause various diseases in wild birds and domesticated poultry. In this study we report the detection and genomic characterization of a partridge (Perdix perdix) origin reovirus strain, D1007/2008. The virus was isolated on cell culture from acute pneumonia and infra-orbital sinusitis. The 23,497 ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2015.11.018
更新日期:2016-04-02 00:00:00
abstract::Ranaviruses (family Iridoviridae, genus Ranavirus) have been recognized as emerging infectious pathogens and caused a great loss to the global biodiversity. Thymidine kinase (TK) and deoxyuridine triphosphatase (dUTPase, DUT, encoded by ORF 67R) are ubiquitous, existing in iridoviruses and other organisms. Previous st...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2016.01.008
更新日期:2016-03-02 00:00:00
abstract::Vesicular stomatitis virus (VSV) is a prototypic nonsegmented negative-strand RNA virus. VSV's broad cell tropism makes it a popular model virus for many basic research applications. In addition, a lack of preexisting human immunity against VSV, inherent oncotropism and other features make VSV a widely used platform f...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2013.06.003
更新日期:2013-09-01 00:00:00
abstract::The main objective of this narrative review is to describe the available evidence on the possible antiviral activity of ozone in patients with COVID-19 and its therapeutic applicability through hospital protocols. Amongst different possible therapies for SARS-CoV-2 pneumonia, ozone therapy seems to have an immunologic...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2020.198207
更新日期:2021-01-02 00:00:00
abstract::The diagnosis of infectious diseases is sometimes difficult because of extensive immunological cross-reactivity between related viral antigens. On the path of constructing sero-specific antigens, we have identified residues involved in sero-specific and cross-reactive recognition of the nucleocapsid proteins (NPs) of ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2008.06.003
更新日期:2008-10-01 00:00:00
abstract::Noroviruses belong to the Caliciviridae family of single-stranded positive-sense RNA viruses. The genus Norovirus includes seven genogroups (designated GI-GVII), of which GI, GII and GIV infect humans. Human noroviruses are responsible for widespread outbreaks of acute gastroenteritis and represent one of the most com...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2016.12.018
更新日期:2017-04-15 00:00:00
abstract::The coronavirus disease 2019 (COVID-19) pandemic has created an urgent need for therapeutics that inhibit the SARS-COV-2 virus and suppress the fulminant inflammation characteristic of advanced illness. Here, we describe the anti-COVID-19 potential of PTC299, an orally bioavailable compound that is a potent inhibitor ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2020.198246
更新日期:2021-01-15 00:00:00
abstract::Bovine enteroviruses, which belong to the Picornaviridae family, can cause clinical symptoms in cattle and are excreted in feces. In this study, a cytolytic virus was isolated from Madin-Darby bovine kidney (MDBK) cells from fecal samples of bovine with severe diarrhea and hemorrhagic intestinal mucosa that had been o...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2014.07.032
更新日期:2014-10-13 00:00:00
abstract::DNA clones representing the small genomic segment of Nephropathia epidemica virus strain Hällnäs B1 (NEV) and Hantaan virus strain 76-118 (HTV) encoding their nucleocapsid proteins were inserted into the E. coli vector pIN-III-ompA for secretion of proteins into the periplasmic space. The complete HTV and NEV nucleoca...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(91)90090-i
更新日期:1991-03-01 00:00:00
abstract::This report provides evidence for the replication of varicella zoster virus (VZV) in Raji cells. Infection was achieved by co-cultivation of Raji cells with VZV-infected human fibroblasts. Replication of VZV, as assessed by immunofluorescence using monoclonal antibodies against VZV-glycoproteins, ranged from 18 to 24%...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(86)90080-8
更新日期:1986-06-01 00:00:00
abstract::Genome segments 1 and 2 of human group C rotavirus 'Bristol' strain were sequenced and their gene-protein coding properties assigned. This work completed the genome sequence of a human group C rotavirus (17,910 bp) and allowed the full gene-protein coding assignment of the 11 segments of dsRNA. Gene 1 is 3309 bp in si...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(01)00442-7
更新日期:2002-02-26 00:00:00
abstract::The hepatitis C virus (HCV) nonstructural protein 3 (NS3) is essential for the processing of the HCV polyprotein, the replication of HCV RNA, and to short circuit innate immunity signaling. NS3 contains an N-terminal domain with protease activity and a C-terminal domain with helicase activity. The two domains communic...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2012.07.007
更新日期:2012-10-01 00:00:00
abstract::Murine acquired immunodeficiency syndrome (MAIDS) induced by a defective LP-BM5 murine leukemia virus (MuLV) produces hematopoietic cytopenias similar to HIV in patients with AIDS. The pathogenesis of MAIDS induced cytopenias remains obscure; however, direct retroviral infection of bone marrow stroma has been implicat...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2005.03.027
更新日期:2005-10-01 00:00:00
abstract::We have determined the post-translational modifications of the major capsid protein, L1 of human papillomavirus (HPV) type 6b. Since this virus cannot be cultured in the laboratory to obtain sufficient material for a study, a recombinant L1 protein produced in a vaccinia virus expression system was used in this invest...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(98)00117-8
更新日期:1999-04-01 00:00:00
abstract::In order to investigate the functional properties of the UL56 gene of herpes simplex virus type 1 (HSV-1), it was necessary to express the UL56 protein in vitro. The DNA sequences corresponding to the open reading frame of the UL56 gene of HSV-1 strain F were amplified from genomic viral DNA by PCR using primers corre...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(94)90017-5
更新日期:1994-07-01 00:00:00
abstract::Aphid species were counted on citrus trees in orchards in Valencia, Spain, in the spring and autumn of 1997, 1998 and 1999. Moericke yellow water traps, the 'sticky shoot' method and counts of established colonies were used in extensive surveys in which 29,502 aphids were recorded and identified. Aphis spiraecola and ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2003.12.018
更新日期:2004-03-01 00:00:00
abstract::Porcine reproductive and respiratory syndrome (PRRS) is a major disease affecting pigs worldwide and resulting in considerable economic losses. While PRRS is a global phenomenon, the causative viruses PRRSV-1 (first detected in Europe) and PRRSV-2 (isolated in North America) are genetically and biologically distinct. ...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2014.12.026
更新日期:2015-04-16 00:00:00
abstract::Major progress in Dengue virus (DENV) biology has resulted from the use of infectious clones obtained through reverse genetics. The construction of these clones is commonly based on high- or low-copy number plasmids, yeast artificial chromosomes, yeast-Escherichia coli shuttle vectors, and bacterial artificial chromos...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2013.12.001
更新日期:2014-02-13 00:00:00
abstract::CVB3 virus tropism and tissue access are modulated by cardiac microvascular endothelial cells (CMVECs) in the context of microvasculature. This study was designed to examine biological behaviors of CMVECs following CVB3 infection and its possible effects on cardiac remodeling. Data demonstrated that CVB3 increased cas...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2012.07.027
更新日期:2012-10-01 00:00:00
abstract::The pathogenesis of chorioallantoic membrane (CAM) infection with herpes simplex virus 1 and 2 (HSV-1 and HSV-2) as well as chick embryo fibroblast (CEF) passaged HSV-1 was studied. It was found that HSV-2 is at least a million-fold more virulent than HSV-1 as measured by pfu/LD50 ratios for the embryo. Serial passage...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(86)90017-1
更新日期:1986-08-01 00:00:00
abstract::A recombinant baculovirus, the genome of which contains DNA encoding Marek's disease virus serotype 1 (MDV1) homolog of glycoprotein D (gD) of herpes simplex virus under the polyhedrin promoter was constructed and designated rAcMDV1gD. Five monoclonal antibodies (MAbs) which recognize the MDV1 homolog of gD (MDV1 gD) ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(95)00063-v
更新日期:1995-10-01 00:00:00
abstract::To identify the parts of retroviral integrase that interact with its DNA substrates, we compared the patterns of target site usage by chimeric enzymes and protein fragments in assays that reveal integrase's non-specific nuclease activities. The central region of 12 chimeric proteins between the human immunodeficiency ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(99)00126-4
更新日期:2000-01-01 00:00:00
abstract::A previously unknown iflavirus has been identified in a laboratory colony of the brown planthopper, Nilaparvata lugens. The iflavirus-like sequence was first identified in contig sequences obtained from transcriptome sequencing (RNA-seq) of the brown planthopper. The complete viral genome was resequenced using the San...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2013.06.005
更新日期:2013-09-01 00:00:00
abstract::The cDNA of the nucleocapsid (core) protein of classical swine fever virus (CSFV) was generated by reverse transcription-polymerase chain reaction (RT-PCR) and cloned into a eukaryotic expression vector. The effect of the recombinant core protein on the transcriptional regulation of cellular as well as viral promoters...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(97)00132-9
更新日期:1998-01-01 00:00:00
abstract::To characterize the genomic mutations of hepatitis E virus (HEV) during consecutive passages associated with adaptation to growth in cell culture, a cloned genotype 3 HEV [pJE03-1760F/wt, starting virus (SV)] was passaged 10 times in A549 cells, and the entire genomic sequence of the passage 10 (P10) progeny was deter...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2016.07.011
更新日期:2016-09-02 00:00:00
abstract::Cultured monolayers of MA-104, Vero 76, SW-13, and DBS-FRhL-2 cells were infected with Marburg (MBG), Ebola-Sudan (EBO-S), Ebola-Zaire (EBO-Z), and Ebola-Reston (EBO-R) viruses (Filoviridae, Filovirus) and examined by electron microscopy to provide ultrastructural details of morphology and morphogenesis of these poten...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(95)00080-1
更新日期:1995-12-01 00:00:00
abstract::We have rescued a transfectant influenza virus, NA/TAIL(-), whose neuraminidase (NA) protein lacks the predicted cytoplasmic tail. The virus was attenuated (one log10 reduction) both in tissue culture and in mouse lungs. Attenuation correlated with a 50% reduction of the level of NA in infected cells and levels of inc...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(95)00017-k
更新日期:1995-06-01 00:00:00