Host miR-26a suppresses replication of porcine reproductive and respiratory syndrome virus by upregulating type I interferons.

abstract：:Two genetic markers--the thymidine kinase gene of herpes simplex virus, and the beta-galactosidase gene of Escherichia coli--were incorporated into the 36K protein gene (IL1 gene according to the nomenclature of the Copenhagen strain of vaccinia virus; Goebel et al., 1990) from the HindIII-P DNA fragment of the LIVP s...

journal_title：Virus research

authors： Shchelkunov SN,Ryazankina OI,Gashnikov PV

更新日期：1993-06-01 00:00:00

abstract：:Variants assigned to GI-23 lineage of infectious bronchitis virus (IBV), formerly called Var2, have circulated for nearly 20 years only in countries of the Middle East. Strains of this lineage were first identified in Israel in 1998. More severe form of the virus appeared in 2006, when the second wave of Var2 epidemic...

journal_title：Virus research

authors： Lisowska A,Sajewicz-Krukowska J,Fusaro A,Pikula A,Domanska-Blicharz K

更新日期：2017-10-15 00:00:00

abstract：:Forty Chinese PCV2 strains collected between 2004 and 2008 were sequenced and their genetic variations were analyzed together with nine previous PCV2 isolates. Phylogenetic analysis indicated that these Chinese PCV2 strains could be divided into four genotypes (PCV-2a, PCV-2b, PCV-2d and PCV-2e), and the genotype PCV-...

journal_title：Virus research

authors： Wang F,Guo X,Ge X,Wang Z,Chen Y,Cha Z,Yang H

更新日期：2009-10-01 00:00:00

abstract：:Outbreaks caused by the highly pathogenic H5N1 avian influenza virus (A/H5N1) devastated the poultry industry in several countries and posed a significant pandemic threat. In addition to culling of infected poultry and vaccination, amantadine has been applied in poultry in some countries to control the spread of the v...

journal_title：Virus research

authors： Abdelwhab EM,Veits J,Mettenleiter TC

更新日期：2017-01-15 00:00:00

abstract：:Apoptosis is frequently induced to inhibit virus replication during infection of Enterovirus 71 (EV71). On the contrary, anti-apoptotic pathway, such as PI3K/Akt pathway, is simultaneously exploited by EV71 to accomplish the viral life cycle. The relationship by which EV71-induced apoptosis and PI3K/Akt signaling path...

journal_title：Virus research

authors： Zhang H,Li F,Pan Z,Wu Z,Wang Y,Cui Y

更新日期：2014-11-04 00:00:00

abstract：:Autophagy is an evolutionarily conserved lysosome-dependent degradation pathway that acts in the maintenance of cellular homeostasis and plays important functions in viral replication and pathogenesis. In this study, we investigated the role of autophagy in the replication of porcine reproductive and respiratory syndr...

journal_title：Virus research

authors： Chen Q,Fang L,Wang D,Wang S,Li P,Li M,Luo R,Chen H,Xiao S

更新日期：2012-02-01 00:00:00

abstract：:The purpose of this study was to test whether the region coding for subgroup envelope specificity was a determinant of oncogenic potential. An avian retrovirus recombinant was constructed to contain the envelope gene (env) determinant for subgroup A of an avian RNA tumor virus in one of the non-oncogenic, endogenous a...

journal_title：Virus research

authors： Wright SE,Bennett DD

更新日期：1986-11-01 00:00:00

abstract：:Avian orthoreoviruses cause various diseases in wild birds and domesticated poultry. In this study we report the detection and genomic characterization of a partridge (Perdix perdix) origin reovirus strain, D1007/2008. The virus was isolated on cell culture from acute pneumonia and infra-orbital sinusitis. The 23,497 ...

journal_title：Virus research

authors： Kugler R,Dandár E,Fehér E,Jakab F,Mató T,Palya V,Bányai K,Farkas SL

更新日期：2016-04-02 00:00:00

abstract：:The uptake of porcine parvovirus (PPV) into host cells, permissive or nonpermissive for PPV replication, was monitored by autoradiography, immunofluorescent microscopy, and dual parameter flow cytometry. While both permissive and nonpermissive cells selectively took up the light (activated) form of the virus from a mi...

journal_title：Virus research

authors： Ridpath JF,Mengeling WL

更新日期：1988-04-01 00:00:00

abstract：:A temperature-sensitive mutant of the Moloney murine leukemia virus-TB, ts1, causes hindlimb paralysis and immunodeficiency in mice. At the restrictive temperature, the envelope precursor polyprotein, gPr80env, is inefficiently processed intracellularly, and this is associated with the neurovirulence of ts1. To test t...

journal_title：Virus research

authors： Yu Y,Kamps CA,Yuen PH,Wong PK

更新日期：1991-03-01 00:00:00

abstract：:The fidelity of poliovirus RNA-dependent RNA polymerase (3D(pol)) was determined using a system based on the fidelity of synthesis of the alpha-lac gene which codes for a subunit of beta-galactosidase. Synthesis products are screened for mutations by an alpha-complementation assay, in which the protein product from al...

journal_title：Virus research

authors： Wells VR,Plotch SJ,DeStefano JJ

更新日期：2001-04-01 00:00:00

abstract：:Thogoto (THO) virus infections of Rhipicephalus appendiculatus ticks were examined using tick hosts immune to the virus. In the first set of experiments, ticks were infected by feeding on viraemic hamsters. Inter-stadial infection of THO virus was not affected when ticks ingested a virus-immune bloodmeal but there was...

journal_title：Virus research

authors： Jones LD,Nuttall PA

更新日期：1989-10-01 00:00:00

abstract：:Quasispecies dynamics mediates adaptability of RNA viruses through a number of mechanisms reviewed in the present article, with emphasis on the medical implications for the hepatitis viruses. We discuss replicative and non-replicative molecular mechanisms of genome variation, modulating effects of mutant spectra, and ...

journal_title：Virus research

authors： Domingo E,Gomez J

更新日期：2007-08-01 00:00:00

abstract：:Damage to the Kupffer and endothelial cells of the liver sinusoids induced by the administration of sublethal doses of frog virus 3 (FV 3) renders A/J mice which are genetically resistant to mouse hepatitis virus type 3 (MHV 3) highly susceptible to this virus. Liver histopathology of these animals revealed typical ne...

journal_title：Virus research

authors： Pereira CA,Steffan AM,Kirn A

更新日期：1984-10-01 00:00:00

abstract：:In situ hybridization and virus titration were used to characterize early stages of rat virus (RV) infection of rat pups after oronasal inoculation. Results suggest that virus enters through the lung and that early viremia leads rapidly to pantropic infection. Cells derived from all three germ layers were infected wit...

journal_title：Virus research

authors： Gaertner DJ,Jacoby RO,Johnson EA,Paturzo FX,Smith AL,Brandsma JL

更新日期：1993-04-01 00:00:00

abstract：:This paper summarizes the progress in the search for hantaviruses and hantavirus infections in Africa. After having collected molecular evidence of an indigenous African hantavirus in 2006, an intensive investigation for new hantaviruses has been started in small mammals. Various novel hantaviruses have been molecular...

journal_title：Virus research

authors： Witkowski PT,Klempa B,Ithete NL,Auste B,Mfune JK,Hoveka J,Matthee S,Preiser W,Kruger DH

更新日期：2014-07-17 00:00:00

abstract：:We have developed a system for the preparation of La Crosse virus (LAC) and Hantaan virus (HTN) pseudotypes using a murine leukemia virus vector. After concentration, the pseudotypes were present in quantities sufficient to analyze cell tropism and neutralization. Cells resistant to LAC could not be infected with the ...

journal_title：Virus research

authors： Ma M,Kersten DB,Kamrud KI,Wool-Lewis RJ,Schmaljohn C,González-Scarano F

更新日期：1999-10-01 00:00:00

abstract：:Confocal microscopy revealed that Rice dwarf virus (RDV) initially accumulated in epithelial cells of the filter chamber of leafhopper vector Nephotettix cincticeps 2 days after acquisition access feeding on diseased plants. Subsequently, RDV accumulation progressed to the anterior midgut, and then spread to the nervo...

journal_title：Virus research

authors： Chen H,Chen Q,Omura T,Uehara-Ichiki T,Wei T

更新日期：2011-09-01 00:00:00

abstract：:The disulphide-linked GP2/3/4 spike of equine arteritis virus (EAV) is essential for virus entry. We showed recently that in transfected cells carbohydrates attached adjacent to the signal peptide of GP3 inhibit cleavage. Here we confirm this unique phenomenon in recombinant viruses with disabled glycosylation sites. ...

journal_title：Virus research

authors： Matczuk AK,Veit M

更新日期：2014-04-01 00:00:00

abstract：:A disease of Rudbeckia hirta (Black-eyed Susan), characterized by severe flower deformation, was observed in Minnesota during 2010-2016. A previously undescribed virus species, named Rudbeckia flower distortion virus (RuFDV, family Caulimoviridae, genus unassigned), was determined to be the causal agent of the disease...

journal_title：Virus research

authors： Lockhart B,Mollov D,Olszewski N,Goldsmith N

更新日期：2017-09-15 00:00:00

abstract：:Species members of the genus Parapoxvirus (PPV) within the family Poxviridae cause contagious pustular dermatitis in small ruminants (Orf virus, ORFV) and mostly mild localized inflammation in cattle (bovine papular stomatitis virus, BPSV and pseudocowpox virus, PCPV). All PPVs are known to be zoonotic, leading to cir...

journal_title：Virus research

authors： Friederichs S,Krebs S,Blum H,Wolf E,Lang H,von Buttlar H,Büttner M

更新日期：2014-03-06 00:00:00

abstract：:The highly heterogeneous porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent responsible for an economically important pig disease with the characteristic symptoms of reproductive losses in breeding sows and respiratory illnesses in young piglets. The virus can be broadly divided into th...

journal_title：Virus research

authors： Lu ZH,Archibald AL,Ait-Ali T

更新日期：2014-12-19 00:00:00

abstract：:The complete nucleotide sequence (2209 nucleotides) of the RNA 3 of the cucumber mosaic virus strain Trk7 was determined. Trk7-CMV possesses two open reading frames which encode the 3a protein (279 amino acids) and the coat protein (218 amino acids). Sequence analysis proved the earlier biological and serological clas...

journal_title：Virus research

authors： Salánki K,Thole V,Balázs E,Burgyán J

更新日期：1994-03-01 00:00:00

abstract：:Vesicular exanthema of swine virus (VESV), the prototype calicivirus, is the etiologic agent of the porcine disease vesicular exanthema of swine (VES). VES is characterized by vesicle formation on the extremities, mouth and snout and causes abortions and stillbirths if infection occurs during pregnancy. VESV is consid...

journal_title：Virus research

authors： Neill JD,Meyer RF,Seal BS

更新日期：1998-03-01 00:00:00

abstract：:Infectious spleen and kidney necrosis virus (ISKNV) is the etiological agent that causes a pandemic and severe disease in fish characteristic of enlarged and damaged spleen and kidney. To identify viral proteins involved in infection and pathogenesis, we characterized five open reading frames (ORFs) of the ISKNV genom...

journal_title：Virus research

authors： Xie J,Zhu J,Yang H,Weng S,Chen C,Chen H,Xie Q,Li M,He J

更新日期：2007-02-01 00:00:00

abstract：:Chicken anemia virus (CAV) is one of the commercially important diseases of poultry worldwide. In Egypt, CAV has been reported to be a potential threat to the commercial poultry sectors. Hence, this study was aimed at isolation and full genomic analysis of CAVs circulating in chicken populations in different geographi...

journal_title：Virus research

authors： Erfan AM,Selim AA,Naguib MM

更新日期：2018-06-02 00:00:00

abstract：:Fifteen stable mouse spleen cell myeloma hybrids (hybridomas) producing monoclonal antibodies to rinderpest virus proteins were produced. The specificity of these monoclonal antibodies was established by radioimmunoprecipitation followed by polyacrylamide gel analysis and immunofluorescence. Nine antibodies were speci...

journal_title：Virus research

authors： Bhavani K,Karande AA,Shaila MS

更新日期：1989-04-01 00:00:00

abstract：:Influenza virus is a negative strand RNA virus and is one of the rare RNA viruses to replicate in the nucleus. The viral RNA is associated with 4 viral proteins to form ribonucleoprotein particles (RNPs). After cell entry the RNPs are dissociated from the viral matrix protein in the low pH of the endosome and are acti...

journal_title：Virus research

authors： Boulo S,Akarsu H,Ruigrok RW,Baudin F

更新日期：2007-03-01 00:00:00

abstract：:Mimivirus' genome includes parts of 5S, 16S and 23S ribosomal RNAs encoded by Acanthamoeba's mitogenome, the giant virus' host. Two non-exclusive hypotheses for rRNA remnants in giant viruses are examined: 1. mitogenomes invade viral genomes as they do for nuclear chromosomes (producing numts); 2. megaviral genomes ev...

journal_title：Virus research

authors： Seligmann H

更新日期：2018-07-15 00:00:00

abstract：:The variability of the Apple stem pitting virus (ASPV) coat protein (CP) gene was investigated. The CP gene of ten virus isolates from apple and pear trees was sequenced. Comparison of all sequenced virus isolates revealed high diversity of the CP gene (70.7-93.5% at the nucleotide level and 77.8-98.7% at the amino ac...

journal_title：Virus research

authors： Komorowska B,Siedlecki P,Kaczanowski S,Hasiów-Jaroszewska B,Malinowski T

更新日期：2011-06-01 00:00:00