Abstract：
:The variability of the Apple stem pitting virus (ASPV) coat protein (CP) gene was investigated. The CP gene of ten virus isolates from apple and pear trees was sequenced. Comparison of all sequenced virus isolates revealed high diversity of the CP gene (70.7-93.5% at the nucleotide level and 77.8-98.7% at the amino acid level). Additionally, one or two deletions in the N-terminal part of the coat protein gene of the studied virus isolates were identified. The ratio of nonsynonymous to synonymous polymorphic sites indicated that purifying selection has acted to eliminate deleterious mutations in coding sites. Moreover, the evidences for recombination in analyzed sequences were provided. It is likely that recombination, along with selection, enhances the speed of elimination of deleterious mutations in ASPV, following the mutational deterministic hypothesis of Kondrashov.
journal_name
Virus Resjournal_title
Virus researchauthors
Komorowska B,Siedlecki P,Kaczanowski S,Hasiów-Jaroszewska B,Malinowski Tdoi
10.1016/j.virusres.2011.03.003subject
Has Abstractpub_date
2011-06-01 00:00:00pages
263-7issue
1-2eissn
0168-1702issn
1872-7492pii
S0168-1702(11)00075-Xjournal_volume
158pub_type
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