Trans-activation of viral tk promoters by proteins encoded by varicella zoster virus open reading frames 61 and 62.

abstract：:In this review, we summarize the researches on animal reservoirs of the SARS coronavirus (SARS-CoV). Masked palm civets were suspected as the origin of the SARS outbreak in 2003 and was confirmed as the direct origin of SARS cases with mild symptom in 2004. Sequence analysis of the SARS-CoV-like virus in masked palm c...

journal_title：Virus research

authors： Shi Z,Hu Z

更新日期：2008-04-01 00:00:00

abstract：:Recent scientific advances are providing an opportunity to revisit strategies for cervical cancer prevention. How to invest health resources wisely, such that clinical benefits are maximized-and opportunity costs are minimized-is a critical question in the setting of new technology. In addition to an intervention's ef...

journal_title：Virus research

authors： Goldie SJ

更新日期：2002-11-01 00:00:00

abstract：:Nucleic acid probes prepared directly from bluetongue virus (BTV) genomic double-stranded RNA (dsRNA) have been used to identify the functionally equivalent genome segments from six distinct isolates of BTV after their separation in both agarose and polyacrylamide gel electrophoresis systems. Variations in the rate, a...

journal_title：Virus research

authors： Pedley S,Mohamed ME,Mertens PP

更新日期：1988-06-01 00:00:00

abstract：:We have recently identified and sequenced a molecular clone of the serogroup 2 simian retrovirus (SRV), D2/RHE/OR/V1, that retains an enhanced ability to infect specific T cell lines. In this report, using deletion mutagenesis, we localized the psi packaging signal, necessary for packaging of D2/RHE/OR/V1 particles, t...

journal_title：Virus research

authors： Li B,Nguyen S,Li X,Machida CA

更新日期：2001-06-01 00:00:00

abstract：:Puumala (PUU) viruses are the predominant etiologic agents of hantavirus infections in Europe. The most important reservoir is the bank vole, Clethrionomys glareolus (Cg), belonging to the subfamily Arvicolinae of the Muridae family. Here we report on the molecular characterization of the first rodent-derived sequence...

journal_title：Virus research

authors： Heiske A,Anheier B,Pilaski J,Volchkov VE,Feldmann H

更新日期：1999-06-01 00:00:00

abstract：:All entero- and rhinovirus RNAs sequenced thus far possess A and U residues at positions corresponding to nucleotides 480 and 525, respectively, of poliovirus type 1. These two nucleotides have been proposed previously to form a base pair. The single exception to this rule appears to be the Sabin type 1 strain, which ...

journal_title：Virus research

authors： Muzychenko AR,Lipskaya GYu,Maslova SV,Svitkin YV,Pilipenko EV,Nottay BK,Kew OM,Agol VI

更新日期：1991-10-01 00:00:00

abstract：:We previously established inducible-hepatitis C virus (HCV) transgenic mice, which expressed the HCV gene (nucleotides 294-3435) encoding the core, E1, E2, and NS2 proteins. The expression of these proteins is regulated by the Cre/loxP system and an adenovirus vector (AdV) that expresses Cre DNA recombinase (Cre) cont...

journal_title：Virus research

authors： Chiyo T,Sekiguchi S,Hayashi M,Tobita Y,Kanegae Y,Saito I,Kohara M

更新日期：2011-09-01 00:00:00

abstract：:The immunopathogenesis of severe hand, foot and mouth disease (HFMD) remains elusive. This study revealed that enterovirus 71 (EV71) epitope-specific CD4+ T cell responses of HFMD patients were skewed toward a Th2 cytokine profile. Patients that demonstrated higher levels of IL-4 expression in their CD4 T cells follow...

journal_title：Virus research

authors： Wei R,Xu L,Zhang N,Zhu K,Yang J,Yang C,Deng C,Zhu Z,De Groot AS,Altmeyer R,Zeng M,Leng Q

更新日期：2013-10-01 00:00:00

abstract：:Squirrel monkey retrovirus (SMRV) is a New World primate type D retrovirus. It was shown that SMRV-related sequences could be detected in another New World species, the skunk. It was further suggested that SMRV and an Old World primate type C retrovirus, baboon endogenous virus (BaEV), may have exchanged their env gen...

journal_title：Virus research

authors： Chiu CN,Mitra R,Chiu IM

更新日期：2003-10-01 00:00:00

abstract：:Human respiratory syncytial virus (HRSV) P protein, 241 amino acid long, is a structural homotetrameric phosphoprotein. Viral transcription and replication processes are dependent on functional P protein interactions inside viral ribonucleoprotein complexes (RNPs). Binding capacity to RNPs proteins and transcription a...

journal_title：Virus research

authors： Asenjo A,Mendieta J,Gómez-Puertas P,Villanueva N

更新日期：2008-03-01 00:00:00

abstract：:Currently, pseudorabies virus (PRV) variant strains are outbreaking in China; these variants belong to genotype II PRV. The traditional Bartha-K61 vaccine has failed to provide complete protection against the emergent variant strains. Therefore, rapid attenuation of current epidemic strains is needed for effective PRV...

journal_title：Virus research

authors： Tang YD,Liu JT,Wang TY,An TQ,Sun MX,Wang SJ,Fang QQ,Hou LL,Tian ZJ,Cai XH

更新日期：2016-10-02 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) is now classified into two distinct variants such as HHV-6 variant A(HHV-6A) and B(HHV-6B) (Ablashi et al., Arch. Virol. 129, 1993, 1-4) and the DNA of HHV-6A strain U1102 was completely sequenced (Gompels et al., Virology 209, 1995, 29-51). We have sequenced a 30-kilobase pair (kbp) (genom...

journal_title：Virus research

authors： Kosuge H,Isegawa Y,Yamanishi K

更新日期：1997-11-01 00:00:00

abstract：:Major progress in Dengue virus (DENV) biology has resulted from the use of infectious clones obtained through reverse genetics. The construction of these clones is commonly based on high- or low-copy number plasmids, yeast artificial chromosomes, yeast-Escherichia coli shuttle vectors, and bacterial artificial chromos...

journal_title：Virus research

authors： Usme-Ciro JA,Lopera JA,Enjuanes L,Almazán F,Gallego-Gomez JC

更新日期：2014-02-13 00:00:00

abstract：:Influenza A (H1N1) virus, a high-risk infectious pathogen, can cause severe acute lung injury leading to significant morbidity and mortality. Angiotensin-converting enzyme 2 (ACE2), a negative regulator of the renin-angiotensin system (RAS), plays a protective role in pathogenesis of acute lung injury. Here, we showed...

journal_title：Virus research

authors： Liu X,Yang N,Tang J,Liu S,Luo D,Duan Q,Wang X

更新日期：2014-06-24 00:00:00

abstract：:To determine the pathogenicity domain and to apply cross protection, Pepper mild mottle virus (PMMoV) point-mutations in the replicase (REP) gene between the methyl-transferase and helicase domains, and deletions truncating pseudoknots in the 3' non-coding region (NCR), were constructed. Some mutants substituting a si...

journal_title：Virus research

authors： Yoon JY,Ahn HI,Kim M,Tsuda S,Ryu KH

更新日期：2006-06-01 00:00:00

abstract：:The surface antigen gene region from five chronic hepatitis B virus (HBV) infected chimpanzees was amplified by PCR and the sequence determined. Sequence comparison confirmed that all of the sequences were chimpanzee hepatitis B virus (chHBV) and they appeared to represent three distinct clusters or branches. To addre...

journal_title：Virus research

authors： Hu X,Javadian A,Gagneux P,Robertson BH

更新日期：2001-11-05 00:00:00

abstract：:The genomes of eight hepatitis A virus (HAV) strains originating from far distant geographic regions such as Europe, North Africa, Middle and North America, Australia and The People's Republic of China were compared by RNase T1 oligonucleotide mapping. For this purpose, the viruses were propagated in cell cultures and...

journal_title：Virus research

authors： Weitz M,Siegl G

更新日期：1985-12-01 00:00:00

abstract：:Tmprss2 is an emerging molecular target which guides cellular infections of SARS-CoV-2, has been earmarked for interventions against the viral pathologies. The study aims to computationally screen and identifies potential miRNAs, following in vitro experimental validation of miRNA-mediated suppression of Tmprss2 for e...

journal_title：Virus research

authors： Kaur T,Kapila S,Kapila R,Kumar S,Upadhyay D,Kaur M,Sharma C

更新日期：2021-01-08 00:00:00

abstract：:Murine cytomegalovirus (MCMV) m137 null mutants, Deltam137A and Deltam137B, were generated by inserting a gpt cassette into a deleted region of the open reading frame. A polyclonal antiserum produced to an Escherichia coli expressed gst-m137 fusion protein was used to show that a 38 kDa polypeptide corresponding to th...

journal_title：Virus research

authors： Visalli RJ,Fairhurst J,Kothandaraman S,Buklan A

更新日期：2002-03-20 00:00:00

abstract：:Quasispecies dynamics mediates adaptability of RNA viruses through a number of mechanisms reviewed in the present article, with emphasis on the medical implications for the hepatitis viruses. We discuss replicative and non-replicative molecular mechanisms of genome variation, modulating effects of mutant spectra, and ...

journal_title：Virus research

authors： Domingo E,Gomez J

更新日期：2007-08-01 00:00:00

abstract：:A molecular epidemiological study was performed on 13 Korean virus isolates, which were collected from wild and domestic animals diagnosed as rabid between 1998 and 2004. Seven samples were from domestic animals such as dogs and cattle infected by rabid raccoon dogs (Nyctereutes procyonoides koreensis), and the rest o...

journal_title：Virus research

authors： Hyun BH,Lee KK,Kim IJ,Lee KW,Park HJ,Lee OS,An SH,Lee JB

更新日期：2005-12-01 00:00:00

abstract：:Serological parameters intend to describe antibody response to influenza vaccine in a population. However, there is uncertainty about the mathematical appropriateness and the biological or clinical meaning of conventionally used parameters. Theoretical considerations and exploration of a data-set of 16 studies with an...

journal_title：Virus research

authors： Beyer WE,Palache AM,Lüchters G,Nauta J,Osterhaus AD

更新日期：2004-07-01 00:00:00

abstract：:The hepatitis C virus (HCV) nonstructural protein 3 (NS3) is essential for the processing of the HCV polyprotein, the replication of HCV RNA, and to short circuit innate immunity signaling. NS3 contains an N-terminal domain with protease activity and a C-terminal domain with helicase activity. The two domains communic...

journal_title：Virus research

authors： Vaughan R,Li Y,Fan B,Ranjith-Kumar CT,Kao CC

更新日期：2012-10-01 00:00:00

abstract：:The Foot-and-mouth disease virus (FMDV) causes important economical losses in livestock farming. In order to develop a novel subunit vaccine against FMDV, we constructed recombinant baculoviruses that display the protein VP1 of FMDV on their surface, with either polar (fused to gp64) or nonpolar (fused to anchor membr...

journal_title：Virus research

authors： Peralta A,Maroniche GA,Alfonso V,Molinari P,Taboga O

更新日期：2013-07-01 00:00:00

abstract：:By Western blot analyzes of expression of avian reovirus proteins, one unknown fragment was detected by an anti-sigmaA monoclonal antibody in virus-infected cells lysate. It was interesting to note that RNA interference against sigmaA resulted in the suppression of the unknown fragment. Using various lengths of sigmaA...

journal_title：Virus research

authors： Ji WT,Lin FL,Wang YC,Shih WL,Lee LH,Liu HJ

更新日期：2010-04-01 00:00:00

abstract：:Eighteen monoclonal antibodies were produced against three Australian bovine enterovirus serogroups. Based on their binding patterns to 14S subunits, natural empty capsids and virions of 4 selected viral isolates (K2577, SL305, 66/27, J2129) in two types of quantitative ELISAs, the 18 antibodies were shown to belong t...

journal_title：Virus research

authors： Zhang AQ,Burgess GW

更新日期：1990-07-01 00:00:00

abstract：:Since 2002 there has been a rise in arthrogryposis/hydranencephaly (AGH) incidence in Israel, caused by Akabane (AKA) and, possibly, Aino viruses. To test the ability to control the disease, three siRNA genes targeted to the S genome segment were designed and prepared in the form of siRNA cassettes. For the design all...

journal_title：Virus research

authors： Levin A,Kutznetova L,Kahana R,Rubinstein-Guini M,Stram Y

更新日期：2006-09-01 00:00:00

abstract：:There are currently no effective drugs to treat serious complications caused by WNV infection. The inhibition of WNV by the pluripotent immunomodulator AS101 [ammonium trichloro(dioxyethylene-0-0')tellurate] was evaluated in vitro and in vivo, and its mechanism was explored. Adding AS101 to Vero cells 1h or 5 min befo...

journal_title：Virus research

authors： Indenbaum V,Bin H,Makarovsky D,Weil M,Shulman LM,Albeck M,Sredni B,Mendelson E

更新日期：2012-06-01 00:00:00

abstract：:Mouse hepatitis virus (MHV) nucleocapsid (N) protein binds to the large, single-stranded, positive-sense viral genomic RNA to form a helical nucleocapsid structure in mature virions. In addition N protein binds the intracellular form of the genomic RNA, all of the MHV subgenomic mRNAs, and expressed non-MHV RNA transc...

journal_title：Virus research

authors： Narayanan K,Kim KH,Makino S

更新日期：2003-12-01 00:00:00

abstract：:Hepatitis E virus (HEV) causes acute or chronic hepatitis in humans and can be transmitted via the fecal-oral route. Pigs are one of the main reservoirs for this infection. Sixty pigs, 4-5 months of age, on a swine herd in Japan had detectable anti-HEV IgG antibodies, and five (8.3%) of them had ongoing infection of g...

journal_title：Virus research

authors： Primadharsini PP,Miyake M,Kunita S,Nishizawa T,Takahashi M,Nagashima S,Tanggis,Ohnishi H,Kobayashi T,Nishiyama T,Jirintai S,Okamoto H

更新日期：2017-08-15 00:00:00