Abstract：
:Eighteen monoclonal antibodies were produced against three Australian bovine enterovirus serogroups. Based on their binding patterns to 14S subunits, natural empty capsids and virions of 4 selected viral isolates (K2577, SL305, 66/27, J2129) in two types of quantitative ELISAs, the 18 antibodies were shown to belong to four groups. Due to the specific reaction of monoclonal antibodies, the four groups likely react with four epitopes. The first epitope was shown mainly on the surface of isolate K2577. The second and the third epitopes were common epitopes shared by all four isolates. These epitopes presented equally well on 14S subunits, natural empty capsids and virions. The fourth epitope was present mainly on the natural empty capsids and shared by most, but not all isolates. The four epitopes seem to be conformation dependent epitopes.
journal_name
Virus Resjournal_title
Virus researchauthors
Zhang AQ,Burgess GWdoi
10.1016/0168-1702(90)90050-lsubject
Has Abstractpub_date
1990-07-01 00:00:00pages
235-46issue
3eissn
0168-1702issn
1872-7492pii
0168-1702(90)90050-Ljournal_volume
16pub_type
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