Abstract:
:A molecular epidemiological study was performed on 13 Korean virus isolates, which were collected from wild and domestic animals diagnosed as rabid between 1998 and 2004. Seven samples were from domestic animals such as dogs and cattle infected by rabid raccoon dogs (Nyctereutes procyonoides koreensis), and the rest of the six samples were from raccoon dogs in the wild. The study was carried out based on the comparison of nucleotide and amino acid sequences of nucleoprotein (N) and glycoprotein (G) coding regions and nucleotide sequence of the G-L intergenic (Psi) non-coding region of the isolates. The similarities of nucleotide and amino acid sequence were at least 97.8 and 98.5%, respectively, between all Korean isolates. Phylogenetic analyses of the isolate showed that they formed a monophyletic group closely related to the Arctic strains but distant from other Asian strains, including Chinese strains. The fact that the raccoon dog is the main epidemic carrier of rabies in Korea and the results of these studies supported the conclusion of previous studies (Kuzmin et al.) that the raccoon dogs take part in the circulation of rabies virus within their natural territories in the Far East. The Korean isolates can be divided into two subgroups. All the topology of the most likelihood tree of Korean isolates using nucleotide and amino acid sequences of N, G and G-L region reflected not the species but the year of isolation and geographical location of the virus isolates. This study presents the detailed description of the molecular epidemiology of rabies virus in Korea.
journal_name
Virus Resjournal_title
Virus researchauthors
Hyun BH,Lee KK,Kim IJ,Lee KW,Park HJ,Lee OS,An SH,Lee JBdoi
10.1016/j.virusres.2005.06.004subject
Has Abstractpub_date
2005-12-01 00:00:00pages
113-25issue
1-2eissn
0168-1702issn
1872-7492pii
S0168-1702(05)00189-9journal_volume
114pub_type
杂志文章相关文献
VIRUS RESEARCH文献大全abstract::The cellular secretory vesicles known as 'exosomes' have emerged as key player in intercellular transport and communication between different eukaryotic in order to maintain body homeostasis. Many pathogenic viruses utilize exosome pathway to efficiently transfer bioactive components from infected cells to naïve cells...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2017.08.009
更新日期:2017-08-15 00:00:00
abstract::Adaptation of the prototype A/FM/1/47 H1N1 strain to mice resulted in selection of the A/FM/1/47-MA variant with increased virulence. Earlier analysis identified mutations in the HA and M1 genes that increase virulence in the mouse. Complete sequence analysis identified mutations in the PB1, PB2, HA, NA, and M1 genes....
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(99)00027-1
更新日期:1999-05-01 00:00:00
abstract::In order to clarify the genetic relationships and dynamics of rabies viruses that are epidemic in Indonesia, we determined and analyzed 1307 nucleotides of nucleoprotein genes of 34 rabies field isolates collected from Sumatra, Java, Kalimantan, Sulawesi and Flores islands. Results of phylogenetic analysis indicated t...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2008.03.001
更新日期:2008-07-01 00:00:00
abstract::We describe a rapid method for genetic characterisation of influenza virus genes using reverse transcription and amplification by polymerase chain reaction (RT/PCR) of all virus segments simultaneously (multiplex RT/PCR) using primers based on the conserved terminal sequences. The product has been shown to be suitable...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(94)90087-6
更新日期:1994-06-01 00:00:00
abstract::Porcine reproductive and respiratory syndrome virus (PRRSV), an arterivirus, belongs to a group of RNA viruses that are cytopathic for macrophages and establish persistent infections. Apoptosis is the presumed mechanism of cell death in monkey kidney cell lines and porcine alveolar macrophages after infection with Eur...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(02)00029-1
更新日期:2002-05-10 00:00:00
abstract::The highly heterogeneous porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent responsible for an economically important pig disease with the characteristic symptoms of reproductive losses in breeding sows and respiratory illnesses in young piglets. The virus can be broadly divided into th...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2014.10.004
更新日期:2014-12-19 00:00:00
abstract::Currently, pseudorabies virus (PRV) variant strains are outbreaking in China; these variants belong to genotype II PRV. The traditional Bartha-K61 vaccine has failed to provide complete protection against the emergent variant strains. Therefore, rapid attenuation of current epidemic strains is needed for effective PRV...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2016.09.004
更新日期:2016-10-02 00:00:00
abstract::To evaluate the mechanism by which a large outbreak of porcine epidemic diarrhea (PED) occurred in Japan, where the majority of sows are vaccinated, we isolated two new strains of PED virus (PEDV) from the intestines of piglets and found that they showed greater similarity to US isolates (group II PEDV) than to the Ja...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2016.06.006
更新日期:2016-08-15 00:00:00
abstract::The resurgence of Chikungunya virus (CHIKV) in the form of unprecedented explosive epidemic after a gap of 32 years in India is a point of major public health concern. In 2007 again there was outbreak in Kerala, India, affecting more than 25,000 cases with many reported mortalities. To understand the molecular basis o...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2008.02.004
更新日期:2008-07-01 00:00:00
abstract::African horse sickness (AHS) is a devastating viral disease affecting equines and has resulted in many disastrous epizootics. To date, no successful therapeutic treatment exists for AHS, and commercially used live-attenuated vaccines have various undesirable side effects. Previous studies have shown that mice inoculat...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2020.198284
更新日期:2021-01-06 00:00:00
abstract::Coronaviruses are responsible for a growing economic, social and mortality burden, as the causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), avian infectious bronchitis virus (IBV) and COVID-19. However, there is a lack of effective antiviral agents f...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2020.197989
更新日期:2020-07-15 00:00:00
abstract::Hepatitis B virus (HBV) surface antigen (HBsAg), which is encoded by the HBV S gene, is conventionally classified into 4 serological subtypes, adw, adr, ayw and ayr. To determine the relationship between the HBsAg seroreactivity and the nucleotide sequence diversity of the HBV S gene, the nucleotide sequences of S gen...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(95)00069-0
更新日期:1995-11-01 00:00:00
abstract::The attenuated equine infectious anemia virus (EIAV) vaccine was the first attenuated lentivirus vaccine to be used in a large-scale application and has been used to successfully control the spread of equine infectious anemia (EIA) in China. To better understand the potential role of cytokines in the pathogenesis of E...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2011.06.028
更新日期:2011-09-01 00:00:00
abstract::Small interfering RNAs (siRNAs) have been shown to direct sequence-specific inhibition of gene expression in mammalian cells. siRNAs are RNA duplexes of 21-23 nucleotides (nts) with approximately 2nt 3' overhangs that can induce degradation of their homologous target mRNAs without interferon responses in mammalian cel...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2004.01.015
更新日期:2004-06-01 00:00:00
abstract::We have rescued a transfectant influenza virus, NA/TAIL(-), whose neuraminidase (NA) protein lacks the predicted cytoplasmic tail. The virus was attenuated (one log10 reduction) both in tissue culture and in mouse lungs. Attenuation correlated with a 50% reduction of the level of NA in infected cells and levels of inc...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(95)00017-k
更新日期:1995-06-01 00:00:00
abstract::Puumala (PUU) virus causes a form of hemorrhagic fever with renal syndrome (HFRS), called nephropathia epidemica (NE), in Europe. HFRS is characterized by an increased capillary permeability, which we hypothesize is caused by hyperactivation of the host immune system, especially cellular immune responses. To identify ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(01)00416-6
更新日期:2002-03-20 00:00:00
abstract::Three dendrimeric peptides were synthesized in order to evaluate their immunogenicity and their potential protection against classical swine fever virus (CSFV) in domestic pigs. Construct 1, an optimized version of a previously used dendrimer, had four copies of a B-cell epitope derived from CSFV E2 glycoprotein conne...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2017.05.020
更新日期:2017-06-15 00:00:00
abstract::The genomes of eight hepatitis A virus (HAV) strains originating from far distant geographic regions such as Europe, North Africa, Middle and North America, Australia and The People's Republic of China were compared by RNase T1 oligonucleotide mapping. For this purpose, the viruses were propagated in cell cultures and...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(85)90020-6
更新日期:1985-12-01 00:00:00
abstract::The molecular mechanism involved in cytopathogenicity of rabies virus has not been fully elucidated yet. A fixed rabies virus Nishigahara strain does not induce clear cytopathic effect (CPE) in mouse neuroblastoma (NA) cells, whereas Ni-CE strain, which was established after 100 passages of Nishigahara strain in chick...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2008.05.011
更新日期:2008-10-01 00:00:00
abstract::For detection of spring viremia of carp virus (SVCV) DNA probes have been constructed using the reverse transcription-polymerase chain reaction (RT-PCR) amplification technique and cDNA cloning in plasmid and phage vectors. The specific primers for amplification of SVCV M and G genes were chosen and synthesized. Studi...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(99)00052-0
更新日期:1999-09-01 00:00:00
abstract::The biogeographical history of rabies can be reconstructed using molecular data. This work describes the genetic characterization of the Rabies virus variant that circulates in the Desmodus rotundus (vampire bat) population in an epizootic area and is transmitted to herbivorous livestock. The N and G genes of this vir...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2009.05.001
更新日期:2009-09-01 00:00:00
abstract::A temperature-sensitive mutant of the Moloney murine leukemia virus-TB, ts1, causes hindlimb paralysis and immunodeficiency in mice. At the restrictive temperature, the envelope precursor polyprotein, gPr80env, is inefficiently processed intracellularly, and this is associated with the neurovirulence of ts1. To test t...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(91)90096-e
更新日期:1991-03-01 00:00:00
abstract::To model HCV resistance to a treatment with interferon-alpha (IFN-alpha) and ribavirin, Huh7 cells, bearing HCV subgenomic replicons, were treated with these compounds for several weeks. Analysis of the cell clones, which were able to support replication of HCV RNA in the presence of high concentrations of these antiv...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2006.12.007
更新日期:2007-04-01 00:00:00
abstract::Japanese encephalitis virus (JEV)-specific RNAs (including 42S RNA) were synthesized in subcellular fractions prepared from infected C6/36 cells. This in vitro RNA synthesis essentially required Mg2+ and four ribonucleotides, and it was enhanced by K+. The amounts of RNA synthesized in vitro (in extracts from JEV-infe...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/0168-1702(89)90078-6
更新日期:1989-08-01 00:00:00
abstract::Kaposi's sarcoma-associated herpesvirus (KSHV) replication and transcription activator (RTA) is necessary and sufficient for the switch from KSHV latency to lytic replication. RTA activates promoters by several mechanisms. RTA can bind to sequences in viral promoters and activate transcription. In addition, RTA intera...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2007.07.019
更新日期:2008-01-01 00:00:00
abstract::The core proteins of epizootic haemorrhagic disease virus (EHDV) have important roles to perform in maintaining the structure and function of the virus. A complete genetic and phylogenetic analysis was therefore performed on these proteins (and the genes that code for them) to allow comparison of the selective pressur...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2009.07.011
更新日期:2009-11-01 00:00:00
abstract::Influenza A (H1N1) virus, a high-risk infectious pathogen, can cause severe acute lung injury leading to significant morbidity and mortality. Angiotensin-converting enzyme 2 (ACE2), a negative regulator of the renin-angiotensin system (RAS), plays a protective role in pathogenesis of acute lung injury. Here, we showed...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2014.03.010
更新日期:2014-06-24 00:00:00
abstract::The sequence of the VP7 gene of two rotaviruses isolated from dogs in southern Italy was determined and the inferred amino acid sequence was compared with that of other rotavirus strains. There was very high nucleotide and amino acid identity between canine strain RV198/95 and other canine strains, and to the human st...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/s0168-1702(00)00230-6
更新日期:2001-04-01 00:00:00
abstract::As master transcription factors for lipogenesis, sterol regulatory element-binding protein-1 (SREBP-1) has two isoforms, SREBP-1a and SREBP-1c. Hepatitis B virus X (HBx) can up-regulate the transcription of both SREBP-1a and SREBP-1c. HBx is a small protein consisting of 154 amino acids. Truncated forms of HBx, often ...
journal_title:Virus research
pub_type: 杂志文章
doi:10.1016/j.virusres.2015.07.011
更新日期:2015-12-02 00:00:00
abstract::Coronaviruses are a large group of enveloped, single-stranded positive-sense RNA viruses that infect a wide range of avian and mammalian species, including humans. The emergence of deadly human coronaviruses, severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (ME...
journal_title:Virus research
pub_type: 杂志文章,评审
doi:10.1016/j.virusres.2014.11.021
更新日期:2015-04-16 00:00:00