Amino acid at position 95 of the matrix protein is a cytopathic determinant of rabies virus.

abstract：:Almost all viruses can be neutralized by antibodies. However, there is some controversy about antibody-mediated neutralization of African swine fever virus (ASFV) with sera from convalescent pigs and about the protective relevance of antibodies in experimentally vaccinated pigs. At present, there is no vaccine availab...

journal_title：Virus research

authors： Escribano JM,Galindo I,Alonso C

更新日期：2013-04-01 00:00:00

abstract：:Retroviruses and retrotransposons package genomic RNA into virus-like particles (VLPs) in a poorly understood process. Expression of the budding yeast retrotransposon Ty3 results in the formation of cytoplasmic Ty3 VLP assembly foci comprised of Ty3 RNA and proteins, and cellular factors associated with RNA processing...

journal_title：Virus research

authors： Clemens K,Bilanchone V,Beliakova-Bethell N,Larsen LS,Nguyen K,Sandmeyer S

更新日期：2013-02-01 00:00:00

abstract：:RNA viruses exist as quasispecies containing many variants within their populations because of the error prone nature of viral RNA-dependent RNA polymerases. Quasispecies are not a simple collection of individual variants. Instead, internal interactions among variants provide quasispecies with unique evolvability. An ...

journal_title：Virus research

authors： Shirogane Y,Watanabe S,Yanagi Y

更新日期：2019-04-15 00:00:00

abstract：:Tissue culture adaptation of infectious bursal disease virus (IBDV) results in alternation of three residues on its major capsid protein VP2 and these residues may engage in receptor binding. Although the key of successful infection of tissue culture adapted IBDV in tissue cultures was defined as the virus entering st...

journal_title：Virus research

authors： Yip CW,Yeung YS,Ma CM,Lam PY,Hon CC,Zeng F,Leung FC

更新日期：2007-01-01 00:00:00

abstract：:We here report the results of an investigation of the effect of interferon on the establishment of new infections by a retrovirus. For this study, we used an infectious but replication-incompetent retrovirus carrying a drug-resistance gene and assayed for infectivity by measuring drug-resistant colony formation. Mouse...

journal_title：Virus research

authors： Kumar R,Sen GC

更新日期：1989-08-01 00:00:00

abstract：:Vesicular exanthema of swine virus (VESV), the prototype calicivirus, is the etiologic agent of the porcine disease vesicular exanthema of swine (VES). VES is characterized by vesicle formation on the extremities, mouth and snout and causes abortions and stillbirths if infection occurs during pregnancy. VESV is consid...

journal_title：Virus research

authors： Neill JD,Meyer RF,Seal BS

更新日期：1998-03-01 00:00:00

abstract：:Double-stranded RNA viruses infecting bacterial hosts belong to the Cystoviridae family. Bacteriophage phi6 is one of the best characterized dsRNA viruses and shares structural as well as functional similarities with other well-studied eukaryotic dsRNA viruses (e.g. L-A, rotavirus, bluetongue virus, and reovirus). The...

journal_title：Virus research

authors： Poranen MM,Tuma R

更新日期：2004-04-01 00:00:00

abstract：:Partial nucleotide sequences of the haemagglutinin (H) gene of 18 measles viruses isolated in the Gambia during 1994 and 1995 show a high degree of homology (> 98.5%) when compared with each other. These sequences form a cluster distinct from measles viruses isolated from other geographic regions and from the sequence...

journal_title：Virus research

authors： Outlaw MC,Jaye A,Whittle HC,Pringle CR

更新日期：1997-05-01 00:00:00

abstract：:Herpesvirus, such as herpes simplex type 1 (HSV-1) acquire their envelope by budding through a modified inner membrane of the nuclear envelope which forms thick and dense patches at the site of budding. This suggests that some of the viral envelope glycoproteins must be transported to the nuclear envelope in order to ...

journal_title：Virus research

authors： Gilbert R,Ghosh HP

更新日期：1993-06-01 00:00:00

abstract：:Although a significant progress has been achieved on dsRNA mediated anti-virus strategy development, there is still no effective means to control the virulent white spot syndrome virus (WSSV). Six double-stranded RNAs specific to different essential genes of WSSV (ie1, ie3, pol (DNA polymerase), rr2 (ribonucleotide re...

journal_title：Virus research

authors： Attasart P,Kaewkhaw R,Chimwai C,Kongphom U,Namramoon O,Panyim S

更新日期：2009-10-01 00:00:00

abstract：:A flow cytometric assay that measures binding of human T-lymphotropic virus type 1 (HTLV-1) virions to target cells was used to investigate the binding process and to screen for compounds affecting viral binding. Results showed that adenosine receptor type 2 antagonists effectively inhibit viral binding at concentrati...

journal_title：Virus research

authors： Hague BF,Zhao TM,Kindt TJ

更新日期：2003-05-01 00:00:00

abstract：:Cold-passaged (CP) mutants derived from the JS strain of wild type wt parainfluenza type 3 virus (PIV3) are being evaluated as candidate live virus vaccines. The wt virus was serially passaged 45 times at low temperature and mutant clones with the cold-adapted (CA), temperature-sensitive (ts), and attenuation (ATT) ph...

journal_title：Virus research

authors： Hall SL,Stokes A,Tierney EL,London WT,Belshe RB,Newman FC,Murphy BR

更新日期：1992-03-01 00:00:00

abstract：:A recombinant baculovirus, the genome of which contains DNA encoding Marek's disease virus serotype 1 (MDV1) homolog of glycoprotein D (gD) of herpes simplex virus under the polyhedrin promoter was constructed and designated rAcMDV1gD. Five monoclonal antibodies (MAbs) which recognize the MDV1 homolog of gD (MDV1 gD) ...

journal_title：Virus research

authors： Ono M,Jang HK,Maeda K,Kawaguchi Y,Tohya Y,Niikura M,Mikami T

更新日期：1995-10-01 00:00:00

abstract：:To investigate the genetic variability and evolution of rabbit hemorrhagic disease virus (RHDV) strains in China, VP60 gene sequences of eight new isolates collected from farms with RHD occurrences in China between 2009 and 2014 were analyzed, and compared with the reference sequence of the vaccine strain WF/China/200...

journal_title：Virus research

authors： Hu B,Fan Z,Wang F,Song Y,Wei H,Liu X,Qiu R,Xu W,Yuan W,Xue J

更新日期：2016-04-02 00:00:00

abstract：:Viruses frequently spread among cells or hosts in groups, with multiple viral genomes inside the same infectious unit. These collective infectious units can consist of multiple viral genomes inside the same virion, or multiple virions inside a larger structure such as a vesicle. Collective infectious units deliver mul...

journal_title：Virus research

authors： Leeks A,Sanjuán R,West SA

更新日期：2019-05-01 00:00:00

abstract：:The nucleotide sequence of the E-3 region genes, the hexon associated protein pVIII genes, and part of the fiber genes coding for the N-terminal tail regions, of porcine adenovirus (PAV) types 1 and 2 were determined. The sizes of the E-3 regions were found to be 1162 and 1222 bp, respectively. The five open reading f...

journal_title：Virus research

authors： Reddy PS,Idamakanti N,Derbyshire JB,Nagy E

更新日期：1996-08-01 00:00:00

abstract：:Genetic characterization was conducted on 17 wild-type measles viruses isolated near Hanoi, Vietnam, during 1998 as well as on eight viruses isolated in the Hunan, Hainan, Shandong, and Anhui provinces of the People's Republic of China during 1995, 1998, and 1999. Previous studies had shown that, compared to wild-type...

journal_title：Virus research

authors： Liffick SL,Thi Thoung N,Xu W,Li Y,Phoung Lien H,Bellini WJ,Rota PA

更新日期：2001-09-01 00:00:00

abstract：:In this study we demonstrated that Macrobrachium rosenbergii nodavirus (MrNV) was able to internalize and replicate in Sf9 insect cells, with levels of infection altered by substances affecting the caveolin-(CAV) mediated endocytosis pathway. The use of Sf9 cells for efficient MrNV replication and propagation was demo...

journal_title：Virus research

authors： Somrit M,Watthammawut A,Chotwiwatthanakun C,Weerachatyanukul W

更新日期：2016-09-02 00:00:00

abstract：:Human adenoviruses have been used for mammalian expression vectors and recombinant vaccines for heterologous antigens. We constructed and characterized an infectious adenovirus recombinant containing core-E1-E2 genes of hepatitis C virus (HCV). The core protein was produced mainly during the early phase of viral infec...

journal_title：Virus research

authors： Seong YR,Lee CH,Im DS

更新日期：1998-06-01 00:00:00

abstract：:Apoptosis is an important mechanism of human immunodeficiency virus type 1 (HIV-1)-induced T-cell depletion. Our recent findings revealed mitogenic stimulation-dependent apoptosis induction in healthy donor-derived peripheral blood T-lymphocytes after adsorption with defective HIV-1 particles through acquirement by a ...

journal_title：Virus research

authors： Kameoka M,Auwanit W,Suzuki S,Horikoshi H,Khlai-Khlam N,Meguro T,Yamada K,Tanaka Y,Yoshihara K,Luftig RB,Ikuta K

更新日期：1998-07-01 00:00:00

abstract：:Broad and potent human monoclonal neutralizing antibodies have considerable potential in the prevention and treatment of acquired immunodeficiency syndrome (AIDS). To identify the key amino acid recognition site contacted with neutralizing antibody Y498, peptides were panned from the PhD-12 peptide library and predict...

journal_title：Virus research

authors： Cao W,Li B,Liu H,Cheng X,Liu Y,Zhao X,Qiao Y

更新日期：2020-08-01 00:00:00

abstract：:Infectious spleen and kidney necrosis virus (ISKNV) is the etiological agent that causes a pandemic and severe disease in fish characteristic of enlarged and damaged spleen and kidney. To identify viral proteins involved in infection and pathogenesis, we characterized five open reading frames (ORFs) of the ISKNV genom...

journal_title：Virus research

authors： Xie J,Zhu J,Yang H,Weng S,Chen C,Chen H,Xie Q,Li M,He J

更新日期：2007-02-01 00:00:00

abstract：:JCPyV and BKPyV are common human polyomaviruses that cause lifelong asymptomatic persistent infections in their hosts. In immunosuppressed individuals, increased replication of JCPyV and BKPyV cause significant disease. JCPyV causes a fatal and rapidly progressing demyelinating disease known as progressive multifocal ...

journal_title：Virus research

authors： O'Hara BA,Rupasinghe C,Yatawara A,Gaidos G,Mierke DF,Atwood WJ

更新日期：2014-08-30 00:00:00

abstract：:This report provides evidence for the replication of varicella zoster virus (VZV) in Raji cells. Infection was achieved by co-cultivation of Raji cells with VZV-infected human fibroblasts. Replication of VZV, as assessed by immunofluorescence using monoclonal antibodies against VZV-glycoproteins, ranged from 18 to 24%...

journal_title：Virus research

authors： Cauda R,Chatterjee S,Tilden AB,Grossi CE,Whitley RJ

更新日期：1986-06-01 00:00:00

abstract：:Human papillomaviruses (HPV) are the known cause for a variety of cancers including cervical and epithelial cancers. The cottontail-rabbit papillomavirus (CRPV) serves as a suitable animal model to study the development of these cancers in vivo. We have previously demonstrated that CRPV-induced skin carcinomas express...

journal_title：Virus research

authors： Mühlen S,Behren A,Iftner T,Plinkert PK,Simon C

更新日期：2009-01-01 00:00:00

abstract：:Tobacco (cv. Xanthi nn) plants were watered with allopurinol [4-hydroxypyrazolo (3,4-d) pyrimidine, HPP], a xanthine oxidoreductase (XOR) inhibitor, to investigate its effects on infection by Tobacco mosaic virus engineered to express the green fluorescent protein (TMV.GFP). TMV.GFP infection was monitored by examinat...

journal_title：Virus research

authors： Silvestri S,Murphy AM,Buonaurio R,Carr JP

更新日期：2008-11-01 00:00:00

abstract：:Adaptation of the prototype A/FM/1/47 H1N1 strain to mice resulted in selection of the A/FM/1/47-MA variant with increased virulence. Earlier analysis identified mutations in the HA and M1 genes that increase virulence in the mouse. Complete sequence analysis identified mutations in the PB1, PB2, HA, NA, and M1 genes....

journal_title：Virus research

authors： Brown EG,Bailly JE

更新日期：1999-05-01 00:00:00

abstract：:To gain more insights into the epidemiology of hantaviruses in China, the hantaviral S, M and L segment sequences were recovered from two Microtus fortis captured in Shenyang and four M. fortis trapped in Yuanjiang in China. Genetic analysis revealed that Shenyang sequences are closely related to the sequences of Fuso...

journal_title：Virus research

authors： Zou Y,Xiao QY,Dong X,Lv W,Zhang SP,Li MH,Plyusnin A,Zhang YZ

更新日期：2008-10-01 00:00:00

abstract：:We describe a rapid method for genetic characterisation of influenza virus genes using reverse transcription and amplification by polymerase chain reaction (RT/PCR) of all virus segments simultaneously (multiplex RT/PCR) using primers based on the conserved terminal sequences. The product has been shown to be suitable...

journal_title：Virus research

authors： Adeyefa CA,Quayle K,McCauley JW

更新日期：1994-06-01 00:00:00

abstract：:Influenza A virus replication and packaging is mediated by cis-acting signals, which are located at the 3' and the 5' end of the viral segments. The terminal residues can be divided into conserved and nonconserved residues. We have constructed a mutant influenza A/WSN/33 virus, which contains multiple mutations in the...

journal_title：Virus research

authors： Bergmann M,Muster T

更新日期：1996-09-01 00:00:00