Abstract:
:The nucleotide sequence of the E-3 region genes, the hexon associated protein pVIII genes, and part of the fiber genes coding for the N-terminal tail regions, of porcine adenovirus (PAV) types 1 and 2 were determined. The sizes of the E-3 regions were found to be 1162 and 1222 bp, respectively. The five open reading frames (ORF) encoded within the sequenced regions of PAV types 1 and 2 shared a high degree of homology with the published sequences of the corresponding ORFs of PAV-3. The E-3 regions of PAV types 1, 2 and 3 were further characterized by Northern blot analysis and 5' and 3' end mapping of the transcripts by S1 nuclease analysis. The results of these experiments indicated that the E-3 regions in these three viruses are shorter and simpler in organization than the E-3 regions of human adenoviruses. A potential promoter for the E-3 regions of these PAVs was identified.
journal_name
Virus Resjournal_title
Virus researchauthors
Reddy PS,Idamakanti N,Derbyshire JB,Nagy Edoi
10.1016/0168-1702(96)01336-6subject
Has Abstractpub_date
1996-08-01 00:00:00pages
99-109issue
2eissn
0168-1702issn
1872-7492pii
0168170296013366journal_volume
43pub_type
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