The evolution of collective infectious units in viruses.

Abstract:

:Viruses frequently spread among cells or hosts in groups, with multiple viral genomes inside the same infectious unit. These collective infectious units can consist of multiple viral genomes inside the same virion, or multiple virions inside a larger structure such as a vesicle. Collective infectious units deliver multiple viral genomes to the same cell simultaneously, which can have important implications for viral pathogenesis, antiviral resistance, and social evolution. However, little is known about why some viruses transmit in collective infectious units, whereas others do not. We used a simple evolutionary approach to model the potential costs and benefits of transmitting in a collective infectious unit. We found that collective infectious units could be favoured if cells infected by multiple viral genomes were significantly more productive than cells infected by just one viral genome, and especially if there were also efficiency benefits to packaging multiple viral genomes inside the same infectious unit. We also found that if some viral sequences are defective, then collective infectious units could evolve to become very large, but that if these defective sequences interfered with wild-type virus replication, then collective infectious units were disfavoured.

journal_name

Virus Res

journal_title

Virus research

authors

Leeks A,Sanjuán R,West SA

doi

10.1016/j.virusres.2019.03.013

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

94-101

eissn

0168-1702

issn

1872-7492

pii

S0168-1702(18)30739-1

journal_volume

265

pub_type

杂志文章
  • Viruses detected in the caecum contents of healthy pigs representing a new genetic cluster in genogroup II of the genus "Norwalk-like viruses".

    abstract::Viruses of the genus 'Norwalk-like viruses' (NLVs) detected in humans have been genetically classified into two major genetic groups, genogroups I and II (GI and GII), which together are made up of at least 14 genetic subgroups. However, a comparable classification of NLVs in other species remains to be carried out. W...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/s0168-1702(02)00107-7

    authors: Sugieda M,Nakajima S

    更新日期:2002-08-01 00:00:00

  • Identification in the sera from patients with advanced cancer of a factor which stimulates gene expression from human immunodeficiency virus type 1.

    abstract::From the sera of patients with advanced cancer, a novel factor called SDF (serum-derived factor) was partially purified. SDF was shown to stimulate transcription from the long terminal repeat (LTR) of human immunodeficiency virus type 1 (HIV-1) by transient CAT assay. It did not stimulate gene expression of various co...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/0168-1702(93)90065-u

    authors: Ogiwara H,Nakamura T,Baba S,Okamoto T

    更新日期:1993-09-01 00:00:00

  • Anti-viral effect of a compound isolated from Liriope platyphylla against hepatitis B virus in vitro.

    abstract::The compound LPRP-Et-97543 was isolated from Liriope platyphylla roots and was observed to have potential anti-viral effects in HepG2.2.15 cells against hepatitis B virus (HBV). The antiviral mode was further clarified, and the HBV-transfected Huh7 cells were used as the platform. During viral gene expression, LPRP-Et...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2014.07.015

    authors: Huang TJ,Tsai YC,Chiang SY,Wang GJ,Kuo YC,Chang YC,Wu YY,Wu YC

    更新日期:2014-11-04 00:00:00

  • Generation of recombinant vaccinia viruses expressing Puumala virus proteins and use in isolating cytotoxic T cells specific for Puumala virus.

    abstract::Puumala (PUU) virus causes a form of hemorrhagic fever with renal syndrome (HFRS), called nephropathia epidemica (NE), in Europe. HFRS is characterized by an increased capillary permeability, which we hypothesize is caused by hyperactivation of the host immune system, especially cellular immune responses. To identify ...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/s0168-1702(01)00416-6

    authors: Terajima M,Van Epps HL,Li D,Leporati AM,Juhlin SE,Mustonen J,Vaheri A,Ennis FA

    更新日期:2002-03-20 00:00:00

  • Antigenic diversity of Akabane virus detected by monoclonal antibodies.

    abstract::The antigenic properties of 21 Japanese field isolates and two Australian strains of Akabane (AKA) virus (Simbu serogroup, bunyavirus) isolated from 1959 to 1990 were compared by enzyme-linked immunosorbent assay (ELISA), plaque-reduction neutralization (PRNT) and hemagglutination inhibition (HI) tests using monoclona...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/s0168-1702(96)01415-3

    authors: Akashi H,Inaba Y

    更新日期:1997-02-01 00:00:00

  • Identification of a novel higher molecular weight isoform of USP7/HAUSP that interacts with the Herpes simplex virus type-1 immediate early protein ICP0.

    abstract::The Herpes simplex virus type-1 (HSV-1) regulatory protein ICP0, a RING-finger E3 ubiquitin ligase, stimulates the onset of viral lytic replication and the reactivation of quiescent viral genomes from latency. Like many ubiquitin ligases ICP0 induces its own ubiquitination, a process that can lead to its proteasome-de...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2008.05.017

    authors: Antrobus R,Boutell C

    更新日期:2008-10-01 00:00:00

  • Human parvovirus B19 experimental infection in human fibroblasts and endothelial cells cultures.

    abstract::With the aim to detect what kind of cells, in addition to erythroid progenitors, could be involved in the pathogenesis of B19 infection in some connective tissue diseases, primary cultures of human fibroblasts (HF) and endothelial cells (HUVEC) were exposed to a B19 positive serum (350 genome copies/cell). The presenc...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2005.05.003

    authors: Zakrzewska K,Cortivo R,Tonello C,Panfilo S,Abatangelo G,Giuggioli D,Ferri C,Corcioli F,Azzi A

    更新日期:2005-12-01 00:00:00

  • RNA structure analysis of alphacoronavirus terminal genome regions.

    abstract::Coronavirus genome replication is mediated by a multi-subunit protein complex that is comprised of more than a dozen virally encoded and several cellular proteins. Interactions of the viral replicase complex with cis-acting RNA elements located in the 5' and 3'-terminal genome regions ensure the specific replication o...

    journal_title:Virus research

    pub_type: 杂志文章,评审

    doi:10.1016/j.virusres.2014.10.001

    authors: Madhugiri R,Fricke M,Marz M,Ziebuhr J

    更新日期:2014-12-19 00:00:00

  • Paired chimpanzee hepatitis B virus (ChHBV) and mtDNA sequences suggest different ChHBV genetic variants are found in geographically distinct chimpanzee subspecies.

    abstract::The surface antigen gene region from five chronic hepatitis B virus (HBV) infected chimpanzees was amplified by PCR and the sequence determined. Sequence comparison confirmed that all of the sequences were chimpanzee hepatitis B virus (chHBV) and they appeared to represent three distinct clusters or branches. To addre...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/s0168-1702(01)00334-3

    authors: Hu X,Javadian A,Gagneux P,Robertson BH

    更新日期:2001-11-05 00:00:00

  • Heterogeneity of the L2 gene of field isolates of bluetongue virus serotype 17 from the San Joaquin Valley of California.

    abstract::Genome segment 2 (L2) from six field isolates of bluetongue virus (BTV) serotype 17 was sequenced by cycling sequencing after the amplification of the viral cDNA by the polymerase chain reaction. The viruses were isolated from sheep, cattle and a goat in the San Joaquin Valley of California during the years 1981 and 1...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/0168-1702(94)90072-8

    authors: de Mattos CA,de Mattos CC,Osburn BI,MacLachlan NJ

    更新日期:1994-01-01 00:00:00

  • Stimulating effect of heat shock on the early stage of human cytomegalovirus replication cycle.

    abstract::The effect of mild heat shock on the replication of human cytomegalovirus (HCMV) was studied in human embryo fibroblasts. Treatment of cell cultures at 44 degrees C for 10 min just before infection or at 24 h post infection (p.i.) shortened HCMV eclipse period and enhanced viral replication, while heat shock performed...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/0168-1702(86)90070-5

    authors: Zerbini M,Musiani M,La Placa M

    更新日期:1986-12-01 00:00:00

  • Risk factors associated with increased bovine leukemia virus proviral load in infected cattle in Japan from 2012 to 2014.

    abstract::Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, a malignant B cell lymphoma. BLV has spread worldwide and causes serious problems. After infection, the BLV genome is integrated into the host DNA and can be amplified during periods of latency. We previously designed degenerate primers us...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2015.08.020

    authors: Ohno A,Takeshima SN,Matsumoto Y,Aida Y

    更新日期:2015-12-02 00:00:00

  • Complete genome sequence of a raccoon rabies virus isolate.

    abstract::The entire genome of a mid-Atlantic raccoon strain rabies virus (RRV) isolated in Canada was sequenced; this is the second North American wildlife rabies virus isolate to be fully characterized. The overall organization and length of the genome was similar to that of other lyssaviruses. The nucleotide sequence identit...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2008.04.029

    authors: Szanto AG,Nadin-Davis SA,White BN

    更新日期:2008-09-01 00:00:00

  • Characterization of a SHIV162P3 variant evolved in an infected rhesus macaque with persistent plasma viremia.

    abstract::Typically plasma viremia is controlled in macaques challenged with R5 tropic SHIV162P3 during the chronic phase of infection. However, in a few infected animals it sustains for a prolonged period. Persistent plasma viremia in two such macaques led to a rapid decline of CD4+ T-cells in blood leading to the induction of...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2010.04.006

    authors: Chung HK,Suschak J,Galmin L,Rose N,Pal R

    更新日期:2010-08-01 00:00:00

  • Replication of varicella zoster virus in Raji cells.

    abstract::This report provides evidence for the replication of varicella zoster virus (VZV) in Raji cells. Infection was achieved by co-cultivation of Raji cells with VZV-infected human fibroblasts. Replication of VZV, as assessed by immunofluorescence using monoclonal antibodies against VZV-glycoproteins, ranged from 18 to 24%...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/0168-1702(86)90080-8

    authors: Cauda R,Chatterjee S,Tilden AB,Grossi CE,Whitley RJ

    更新日期:1986-06-01 00:00:00

  • Inhibition of white spot syndrome virus replication in Penaeus monodon by combined silencing of viral rr2 and shrimp PmRab7.

    abstract::Although a significant progress has been achieved on dsRNA mediated anti-virus strategy development, there is still no effective means to control the virulent white spot syndrome virus (WSSV). Six double-stranded RNAs specific to different essential genes of WSSV (ie1, ie3, pol (DNA polymerase), rr2 (ribonucleotide re...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2009.06.018

    authors: Attasart P,Kaewkhaw R,Chimwai C,Kongphom U,Namramoon O,Panyim S

    更新日期:2009-10-01 00:00:00

  • A review of studies on animal reservoirs of the SARS coronavirus.

    abstract::In this review, we summarize the researches on animal reservoirs of the SARS coronavirus (SARS-CoV). Masked palm civets were suspected as the origin of the SARS outbreak in 2003 and was confirmed as the direct origin of SARS cases with mild symptom in 2004. Sequence analysis of the SARS-CoV-like virus in masked palm c...

    journal_title:Virus research

    pub_type: 杂志文章,评审

    doi:10.1016/j.virusres.2007.03.012

    authors: Shi Z,Hu Z

    更新日期:2008-04-01 00:00:00

  • Tolerance and immune response to the porcine endogenous retrovirus in German landrace pigs immunised with viral proteins.

    abstract::Immunisation of goats, mice, rats, rabbits, guinea pigs, and hamsters with the recombinant ectodomain of the porcine endogenous retrovirus (PERV) transmembrane envelope (TM) protein (p15E) induced binding and neutralising immune antibodies in all animals. In contrast, no antibodies were induced when pigs were immunise...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2015.05.019

    authors: Denner J,Petersen B,Niemann H

    更新日期:2015-10-02 00:00:00

  • Infectious salmon anaemia virus nuclear export protein is encoded by a spliced gene product of genomic segment 7.

    abstract::Infectious salmon anaemia virus (ISAV) is an orthomyxovirus causing anaemia and circulatory disease with high mortality in farmed Atlantic salmon (Salmo salar). Orthomyxoviruses are unusual as RNA viruses as they replicate in the nucleus and some viral transcripts undergo splicing. The nuclear replication necessitates...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2013.07.001

    authors: Ramly RB,Olsen CM,Braaen S,Rimstad E

    更新日期:2013-10-01 00:00:00

  • The interaction between KSHV RTA and cellular RBP-Jkappa and their subsequent DNA binding are not sufficient for activation of RBP-Jkappa.

    abstract::Kaposi's sarcoma-associated herpesvirus (KSHV) replication and transcription activator (RTA) is necessary and sufficient for the switch from KSHV latency to lytic replication. RTA activates promoters by several mechanisms. RTA can bind to sequences in viral promoters and activate transcription. In addition, RTA intera...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2007.07.019

    authors: Papugani A,Coleman T,Jones C,Zhang L

    更新日期:2008-01-01 00:00:00

  • Nucleotide sequence comparison of the M1 genome segment of reovirus type 1 Lang and type 3 Dearing.

    abstract::The mammalian reoviruses possess a genome composed of 10 double stranded RNA segments. The serotype 1 strain Lang M1 segment was sequenced and compared to the published type 3 sequence. Both segments were 2304 base-pairs long coding for the mu 2 protein predicted to be 736 amino acids long. The sequences were highly c...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/0168-1702(92)90042-8

    authors: Zou S,Brown EG

    更新日期:1992-02-01 00:00:00

  • Heterogeneous nuclear ribonucleoprotein C binds exclusively to the functionally important UUUUU-motifs in the human papillomavirus type-1 AU-rich inhibitory element.

    abstract::We have previously identified an inhibitory, 57 nt AU-rich sequence in the HPV-1 late 3' UTR, termed as the HPV-1 AU-rich element (h1ARE). It contains two types of functionally important motifs: two AUUUA sequences and three UUUUU sequences. We have shown that the h1ARE interacts with heterogeneous nuclear ribonucleop...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/s0168-1702(00)00238-0

    authors: Sokolowski M,Schwartz S

    更新日期:2001-03-01 00:00:00

  • Nuclear localization and intramolecular cleavage of N-terminally deleted NS5A protein of hepatitis C virus.

    abstract::The full-size NS5A (NS5A-F) of hepatitis C virus is localized in the cytoplasm despite the presence of a functional nuclear localization signal (NLS) in its C-terminal region (amino acids (aa) 354-362). In the present study, we demonstrated that a short stretch of sequence near the N-terminus of NS5A (aa 27-38) masked...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/s0168-1702(00)00206-9

    authors: Song J,Nagano-Fujii M,Wang F,Florese R,Fujita T,Ishido S,Hotta H

    更新日期:2000-09-25 00:00:00

  • Exchange of genetic sequences of long terminal repeat and the env gene by a promiscuous primate type D retrovirus.

    abstract::Squirrel monkey retrovirus (SMRV) is a New World primate type D retrovirus. It was shown that SMRV-related sequences could be detected in another New World species, the skunk. It was further suggested that SMRV and an Old World primate type C retrovirus, baboon endogenous virus (BaEV), may have exchanged their env gen...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/s0168-1702(03)00178-3

    authors: Chiu CN,Mitra R,Chiu IM

    更新日期:2003-10-01 00:00:00

  • Multiple pathways for establishment of poliovirus infection.

    abstract::Poliovirus (PV) infects susceptible cells through poliovirus receptor (PVR), which functions to bind virus and to convert its conformation. To study early infection process of PV, infection systems were employed using in vitro cultured cells and in vivo neural pathway of PVR transgenic (Tg) mice. For in vitro study, m...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/s0168-1702(99)00040-4

    authors: Arita M,Ohka S,Sasaki Y,Nomoto A

    更新日期:1999-08-01 00:00:00

  • Analysis of genome segments from six different isolates of bluetongue virus using RNA-RNA hybridisation: a generalised coding assignment for bluetongue viruses.

    abstract::Nucleic acid probes prepared directly from bluetongue virus (BTV) genomic double-stranded RNA (dsRNA) have been used to identify the functionally equivalent genome segments from six distinct isolates of BTV after their separation in both agarose and polyacrylamide gel electrophoresis systems. Variations in the rate, a...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/0168-1702(88)90078-0

    authors: Pedley S,Mohamed ME,Mertens PP

    更新日期:1988-06-01 00:00:00

  • Downregulation of angiotensin-converting enzyme 2 by the neuraminidase protein of influenza A (H1N1) virus.

    abstract::Influenza A (H1N1) virus, a high-risk infectious pathogen, can cause severe acute lung injury leading to significant morbidity and mortality. Angiotensin-converting enzyme 2 (ACE2), a negative regulator of the renin-angiotensin system (RAS), plays a protective role in pathogenesis of acute lung injury. Here, we showed...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2014.03.010

    authors: Liu X,Yang N,Tang J,Liu S,Luo D,Duan Q,Wang X

    更新日期:2014-06-24 00:00:00

  • Dual ATPase and GTPase activity of the replication-associated protein (Rep) of beak and feather disease virus.

    abstract:BACKGROUND:Psittacine beak and feather disease affects parrots resulting in an immunosuppressive disease that is often characterized by an abnormal shape and growth of the animal's beak, feathers, and claws. Beak and feather disease virus (BFDV) is a single-stranded circular DNA virus and is classified as a member of t...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2015.12.001

    authors: Huang SW,Liu HP,Chen JK,Shien YW,Wong ML,Wang CY

    更新日期:2016-02-02 00:00:00

  • Effect of lysosomotropic compounds on early events in foot-and-mouth disease virus replication.

    abstract::The effect of three lysosomotropic compounds, chloroquine, monensin and NH4Cl, on the replication of foot-and-mouth disease virus (FMDV) type A12 was studied. Viral replication was almost totally inhibited by 0.5 mM chloroquine, 50 microM monensin, or 25 mM NH4Cl. Monensin and NH4Cl affected replication when added eit...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/0168-1702(87)90032-3

    authors: Baxt B

    更新日期:1987-05-01 00:00:00

  • RING finger proteins of infectious spleen and kidney necrosis virus (ISKNV) function as ubiquitin ligase enzymes.

    abstract::Infectious spleen and kidney necrosis virus (ISKNV) is the etiological agent that causes a pandemic and severe disease in fish characteristic of enlarged and damaged spleen and kidney. To identify viral proteins involved in infection and pathogenesis, we characterized five open reading frames (ORFs) of the ISKNV genom...

    journal_title:Virus research

    pub_type: 杂志文章

    doi:10.1016/j.virusres.2006.09.003

    authors: Xie J,Zhu J,Yang H,Weng S,Chen C,Chen H,Xie Q,Li M,He J

    更新日期:2007-02-01 00:00:00