Abstract：
:The surface antigen gene region from five chronic hepatitis B virus (HBV) infected chimpanzees was amplified by PCR and the sequence determined. Sequence comparison confirmed that all of the sequences were chimpanzee hepatitis B virus (chHBV) and they appeared to represent three distinct clusters or branches. To address the question of whether the three branches represented recently identified subspecies of chimpanzees, we determined the sequence of the mitochondrial DNA hypervariable D loop from hair samples obtained from these five chimpanzees. The results indicated that the three chHBV branches reflected three distinct subspecies of chimpanzees that are from different geographic regions in West Africa. The complete HBV sequence from members of the Pan troglodytes troglodytes cluster and the Pan troglodytes verus cluster are in the published literature; we determined the complete genome sequence for the third branch of HBV present in Pan troglodytes vellerosus.
journal_name
Virus Resjournal_title
Virus researchauthors
Hu X,Javadian A,Gagneux P,Robertson BHdoi
10.1016/s0168-1702(01)00334-3subject
Has Abstractpub_date
2001-11-05 00:00:00pages
103-8issue
1-2eissn
0168-1702issn
1872-7492pii
S0168170201003343journal_volume
79pub_type
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