Abstract：
:Genome segment 2 (L2) from six field isolates of bluetongue virus (BTV) serotype 17 was sequenced by cycling sequencing after the amplification of the viral cDNA by the polymerase chain reaction. The viruses were isolated from sheep, cattle and a goat in the San Joaquin Valley of California during the years 1981 and 1990. These viruses exhibit divergent patterns of neutralization with BTV 17-specific monoclonal antibodies. The six L2 genes of the BTV 17 field isolates all encode a protein of 955 amino acids. Similarity of the nucleotide sequences of the L2 genes with respect to the prototype strain ranges between 93.8% and 95.1%, whereas the similarity between the field isolates ranges from 96.8% to 99.1%. Although very closely related, the L2 gene of each virus is distinct. Furthermore, mutations in the L2 gene of field isolates of BTV do not consistently follow a linear pattern of accumulation over time. Some amino acid changes in the VP2 protein of field strains were conserved over time, whereas others were not correlated with the year of isolation and some substitutions were unique to individual viruses. The predicted VP2s constitute a group of non-identical, but closely related proteins. Phylogenetic analyses suggest that the viral variants which co-circulate in the San Joaquin Valley could evolve by different evolutionary pathways.
journal_name
Virus Resjournal_title
Virus researchauthors
de Mattos CA,de Mattos CC,Osburn BI,MacLachlan NJdoi
10.1016/0168-1702(94)90072-8subject
Has Abstractpub_date
1994-01-01 00:00:00pages
67-87issue
1eissn
0168-1702issn
1872-7492pii
0168-1702(94)90072-8journal_volume
31pub_type
杂志文章相关文献
VIRUS RESEARCH文献大全abstract：:Citrus psorosis (CPsV) and Mirafiori lettuce big-vein virus (MiLBVV) belong to the family Ophioviridae, plant viruses with filamentous nucleocapsids and segmented genomes of negative polarity, causing the worldwide distributed citrus psorosis and lettuce big-vein diseases, respectively. To gain insight into the replic...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2012.08.005
更新日期：2012-12-01 00:00:00
abstract：:Bovine herpesvirus-1 (BoHV-1) causes disease in cattle with varied clinical forms. In the U.S. there are two BoHV1 subtypes, BoHV-1.1 and BoHV-1.2b. Control programs in North America incorporate modified live (MLV) or killed (KV) viral vaccines. However, BoHV-1 strains continue to be isolated from diseased animals or ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2016.06.017
更新日期：2016-09-02 00:00:00
abstract：:The immune response to a naked plasmid DNA encoding the nucleoprotein (N protein) of porcine transmissible gastroenteritis virus (TGEV) was investigated in this study. A complementary DNA of the entire N gene was amplified by RT-PCR, and inserted into a mammalian expression vector (pcDNA3.1) to construct a recombinant...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/s0168-1702(01)00333-1
更新日期：2001-11-28 00:00:00
abstract：:Tobacco mosaic virus (TMV) is a positive-sense plant RNA virus which has a wide host range and a worldwide distribution. Other than a troublesome pathogen, TMV is regarded as a model system pioneering biologic research for a century. The tomato strain of TMV has been recognized to be a distinct tobamovirus as the toma...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2011.09.006
更新日期：2012-01-01 00:00:00
abstract：:To investigate the evolutionary origins of proteins encoded by the Poxviridae family of viruses, we examined all poxvirus protein coding genes using a method of characterizing and visualizing the similarity between these proteins and taxonomic subsets of proteins in GenBank. Our analysis divides poxvirus proteins into...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2009.05.006
更新日期：2009-09-01 00:00:00
abstract：:Rice false smut caused by Ustilaginoidea virens is a destructive disease in many rice-growing areas. Mycoviruses have been described in many fungal species, but there is little information regarding mycoviruses in U. virens. In this study, double-stranded (ds) RNA banding patterns were assessed in 198 wild-type isolat...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2014.08.022
更新日期：2015-01-02 00:00:00
abstract：:The human poliovirus receptor (PVR) is a cell surface protein with a multitude of functions in human biology. PVR was initially identified as the receptor for the human poliovirus and recent discoveries have given a greater insight into both its morphology and its function. Alternative splicing of the PVR gene results...
journal_title：Virus research
pub_type： 杂志文章,评审
doi：10.1016/j.virusres.2017.09.001
更新日期：2017-10-15 00:00:00
abstract：:Quasispecies dynamics mediates adaptability of RNA viruses through a number of mechanisms reviewed in the present article, with emphasis on the medical implications for the hepatitis viruses. We discuss replicative and non-replicative molecular mechanisms of genome variation, modulating effects of mutant spectra, and ...
journal_title：Virus research
pub_type： 杂志文章,评审
doi：10.1016/j.virusres.2007.02.001
更新日期：2007-08-01 00:00:00
abstract：:Pseudorabies virus (PrV), a member of herpesviridae alphaherpes subfamily, can infect human cells in vitro. However, the transmission to Old World primates including humans is strongly restricted. In this study, we report the neutralizing activity of normal human serum against PrV grown in CPK cells derived from pig. ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2003.09.008
更新日期：2004-01-01 00:00:00
abstract：:Influenza A viruses are characterized by a unique genome structure, causing genetic instability, especially to the genes of haemagglutinin and neuraminidase. The objectives of this research was molecular and phylogenetic analysis of influenza A(H3N2) strains that circulated in Northern Greece since 2004, particularly ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2009.07.006
更新日期：2009-11-01 00:00:00
abstract：:To evaluate the mechanism by which a large outbreak of porcine epidemic diarrhea (PED) occurred in Japan, where the majority of sows are vaccinated, we isolated two new strains of PED virus (PEDV) from the intestines of piglets and found that they showed greater similarity to US isolates (group II PEDV) than to the Ja...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2016.06.006
更新日期：2016-08-15 00:00:00
abstract：:The encephalomyocarditis (EMC) virus-induced diabetes-like syndrome in mouse inbred strains was used as a model to study the insulin-dependent diabetes mellitus (IDDM). Our investigations were performed with two EMC virus variants, PV2 and PV7. After infection of SJL mice with 10(5) PFU of PV2 about 70% of the animals...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/0168-1702(95)01257-5
更新日期：1996-04-01 00:00:00
abstract：:Theiler's murine encephalomyelitis virus is divided into two subgroups on the basis of their different biological activities. GDVII subgroup strains cause acute and fatal encephalomyelitis in mice, while TO or DA subgroup strains cause non-fatal polioencephalomyelitis in weanling mice followed by virus persistence and...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2009.11.004
更新日期：2010-02-01 00:00:00
abstract：:Fruit trees of temperate and tropical climates are of great economical importance worldwide and several viruses have been reported affecting their productivity and longevity. Fruit trees of different Brazilian regions displaying virus-like symptoms were evaluated for infection by circular DNA viruses. Seventy-four fru...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2015.07.005
更新日期：2015-12-02 00:00:00
abstract：:Rosellinia necatrix is responsible for the white rot root disease of avocado in Southern Spain. Entoleuca sp. is a fungus isolated from roots of these same trees, but it is not pathogenic in avocado. Here, we describe two new species of partitiviruses detected in isolates of the avocado sympatric fungi Entoleuca sp. a...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2020.198020
更新日期：2020-08-01 00:00:00
abstract：:The family Circoviridae comprises a large group of small circular single-stranded DNA viruses with several members causing severe pig and poultry diseases. In recent years the number of new viruses within the family has had an explosive increase showing a high level of genetic diversity and a broad host range. In this...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2018.04.012
更新日期：2018-05-02 00:00:00
abstract：:The glycoprotein (G) is the only surface protein of the lyssavirus particle and the only viral product known to be capable of eliciting the production of neutralizing antibodies. In this study, the isolation of escape mutants resistant to monoclonal antibody (Mab) neutralization was attempted by a selection strategy e...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2016.04.019
更新日期：2016-07-15 00:00:00
abstract：:The hepatitis C virus (HCV) nonstructural protein 3 (NS3) is essential for the processing of the HCV polyprotein, the replication of HCV RNA, and to short circuit innate immunity signaling. NS3 contains an N-terminal domain with protease activity and a C-terminal domain with helicase activity. The two domains communic...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2012.07.007
更新日期：2012-10-01 00:00:00
abstract：:Phylogenetic analysis has been extensively used as a tool for the reconstruction of epidemiological relations for research or for forensic purposes. It was our objective to assess the sensitivity of different phylogenetic methods and various phylogenetic programs to reconstruct epidemiological links among HIV-1 infect...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2012.03.002
更新日期：2012-06-01 00:00:00
abstract：:Lepidopteran nucleopolyhedroviruses have distinct viral tissue tropisms in host larvae. We previously identified the Bm8 gene of Bombyx mori nucleopolyhedrovirus (BmNPV), the product of which inhibits viral propagation in the middle silk gland (MSG). However, it is unknown whether this inhibitory function of the Bm8 p...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2018.03.011
更新日期：2018-04-02 00:00:00
abstract：:The morbidity and mortality of coxsackievirus A10 (CVA10)-associated hand, foot, and mouth disease (HFMD) have been increasing in recent years, while few studies on the vaccine and animal model of CVA10 have been reported. Here, we first established a CVA10-infected gerbil model and employed it to evaluate the immunop...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2020.198067
更新日期：2020-09-01 00:00:00
abstract：:We have investigated the infection of Aedes albopictus (mosquito) cell clones by Sindbis virus. Variation in the multiplicity of infection (MOI) from ranges of 50-0.00005 pfu/cell was determined to have no effect on the progression of the infection to high acute phase titer, suggesting that intracellular factors alone...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/s0168-1702(97)01461-5
更新日期：1997-07-01 00:00:00
abstract：:The nucleotide sequence of the matrix gene (M) of a recently identified morbillivirus, phocid distemper virus (PDV), was determined and the amino acid composition deduced. The M gene of PDV shared many characteristics with the corresponding gene in other morbilliviruses. The nucleotide homology with the closely relate...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/0168-1702(92)90064-g
更新日期：1992-04-01 00:00:00
abstract：:A temperature-sensitive mutant of the Moloney murine leukemia virus-TB, ts1, causes hindlimb paralysis and immunodeficiency in mice. At the restrictive temperature, the envelope precursor polyprotein, gPr80env, is inefficiently processed intracellularly, and this is associated with the neurovirulence of ts1. To test t...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/0168-1702(91)90096-e
更新日期：1991-03-01 00:00:00
abstract：:A recombinant baculovirus containing a cDNA which encodes haemagglutinin-neuraminidase (HN) of Newcastle disease virus (NDV) was constructed. Spodoptera frugiperda cells infected with this recombinant virus produced a large amount of HN glycoprotein similar to the authentic HN in size. The recombinant HN glycoprotein ...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/0168-1702(91)90059-5
更新日期：1991-06-01 00:00:00
abstract：:Porcine reproductive and respiratory syndrome (PRRS) is a major disease affecting pigs worldwide and resulting in considerable economic losses. While PRRS is a global phenomenon, the causative viruses PRRSV-1 (first detected in Europe) and PRRSV-2 (isolated in North America) are genetically and biologically distinct. ...
journal_title：Virus research
pub_type： 杂志文章,评审
doi：10.1016/j.virusres.2014.12.026
更新日期：2015-04-16 00:00:00
abstract：:Non-structural protein1β (Nsp1β) of porcine reproductive and respiratory syndrome virus (PRRSV) has been recognized to be involved in suppressing the host innate immune response and mediating viral subgenomic mRNA transcription. In the present study, we have analyzed the interaction of Nsp1β of Chinese highly pathogen...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2012.08.002
更新日期：2012-10-01 00:00:00
abstract：:A double-stranded (ds) RNA, approximately 9.5kb in size; was identified in the MVC86 isolate of Valsa ceratosperma. Complete sequence of the dsRNA revealed a 9543-bp segment (excluding the 3' poly-A tail) that is predicted to encode a single large protein (P330). P330 has 63%, 49%, and 55% amino acid sequence identiti...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/j.virusres.2012.02.008
更新日期：2012-05-01 00:00:00
abstract：:Infection by the human immunodeficiency virus type 1 (HIV-1) is initiated through interaction of its exterior envelope glycoprotein gp120 with the CD4 receptor on target cells. To address the possible role of N-glycosylation of HIV-1 gp120 in binding CD4, we mutated different conserved N-glycosylation site Asn-residue...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/0168-1702(90)90085-p
更新日期：1990-12-01 00:00:00
abstract：:Human adenoviruses have been used for mammalian expression vectors and recombinant vaccines for heterologous antigens. We constructed and characterized an infectious adenovirus recombinant containing core-E1-E2 genes of hepatitis C virus (HCV). The core protein was produced mainly during the early phase of viral infec...
journal_title：Virus research
pub_type： 杂志文章
doi：10.1016/s0168-1702(98)00043-4
更新日期：1998-06-01 00:00:00
