Abstract:
:Blackberry yellow vein disease is the most important viral disease of blackberry in the United States. Experiments were conducted to characterize a new virus identified in symptomatic plants. Molecular analysis revealed a genome organization resembling Grapevine leafroll-associated virus 3, the type species of the genus Ampelovirus in the family Closteroviridae. The genome of the virus, provisionally named blackberry vein banding associated virus (BVBaV), consists of 18,643 nucleotides and contains 10 open reading frames (ORFs). These ORFs encode closterovirid signature replication-associated and quintuple gene block proteins, as well as four additional proteins of unknown function. Phylogenetic analyses of taxonomically relevant products consistently placed BVBaV in the same cluster with GLRaV-3 and other members of the subgroup I of the genus Ampelovirus. The virus population structure in the U.S. was studied using the replication associated polyprotein 1a, heat shock 70 homolog and minor coat proteins of 25 isolates. This study revealed significant intra-species variation without any clustering among isolates based on their geographic origin. Further analyses indicated that these proteins are under stringent purifying selections. High genetic variability and incongruent clustering of isolates suggested the possible involvement of recombination in the evolution of BVBaV.
journal_name
Virus Resjournal_title
Virus researchauthors
Thekke-Veetil T,Aboughanem-Sabanadzovic N,Keller KE,Martin RR,Sabanadzovic S,Tzanetakis IEdoi
10.1016/j.virusres.2013.09.039subject
Has Abstractpub_date
2013-12-26 00:00:00pages
234-40issue
2eissn
0168-1702issn
1872-7492pii
S0168-1702(13)00346-8journal_volume
178pub_type
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