Sleep and neurochemical modulation by the nuclear peroxisome proliferator-activated receptor α (PPAR-α) in rat.

abstract：:The effect of apamin, a bee venom toxin, on the action potential and the spike after hyperpolarization was studied in bullfrog sympathetic ganglion cells. Apamin reduced the duration of the afterhyperpolarization but did not affect the maximum rates of rise and fall of Na+- and Ca2+-dependent action potentials. In the...

journal_title：Neuroscience research

authors： Koyano K,Abe T

更新日期：1985-12-01 00:00:00

abstract：:Short-interval intracortical inhibition (SICI) acting on the first dorsal interosseus was measured using paired-pulse transcranial magnetic stimulation (interstimulus interval=2ms) in samples of young and healthy older subjects and correlated with manual dexterity measured with the Purdue Pegboard test and two isometr...

journal_title：Neuroscience research

authors： Marneweck M,Loftus A,Hammond G

更新日期：2011-08-01 00:00:00

abstract：:Most imaging studies of the enteric nervous system (ENS) that regulates the function of the gastrointestinal tract are so far performed using preparations isolated from animals, thus hindering the understanding of the ENS function in vivo. Here we report a method for imaging the ENS cellular network activity in living...

journal_title：Neuroscience research

authors： Motegi Y,Sato M,Horiguchi K,Ohkura M,Gengyo-Ando K,Ikegaya Y,Fusamae Y,Hongo Y,Suzuki M,Ogawa K,Takaki M,Nakai J

更新日期：2020-02-01 00:00:00

abstract：:The current study evidenced hypothesis that mitochondrial dysfunction-oxidative stress-dependent apoptotic pathways play a critical role in degeneration of dopaminergic neurons in Parkinson's disease. Model of rotenone-induced parkinsonism in rats produced decrease in striatal complex I activity and reduced glutathion...

journal_title：Neuroscience research

authors： Abdin AA,Sarhan NI

更新日期：2011-12-01 00:00:00

abstract：:To investigate the functional organization in the monkey inferotemporal cortex, which is the last exclusively visual area along the ventral visual cortical pathway, optical imaging based on intrinsic signals was carried out. We first conducted single-cell recordings with microelectrodes and determined the features cri...

journal_title：Neuroscience research

authors： Wang G,Tanifuji M,Tanaka K

更新日期：1998-09-01 00:00:00

abstract：:Disturbed circadian rhythmicity is associated with human diseases such as sleep and mood disorders. However, study of human endogenous circadian rhythm is laborious and time-consuming, which hampers the elucidation of diseases. It has been reported that peripheral tissues exhibit circadian rhythmicity as the suprachia...

journal_title：Neuroscience research

authors： Ebisawa T,Numazawa K,Shimada H,Izutsu H,Sasaki T,Kato N,Tokunaga K,Mori A,Honma K,Honma S,Shibata S

更新日期：2010-02-01 00:00:00

abstract：:The present study was performed to determine whether the voltage gated Cl- channel (CLC) expression is altered in the hippocampus of seizure sensitive (SS) gerbils, and to identify the strong fast paired-pulse inhibition in the dentate gyrus of SS gerbils is associated with altered CLC expression. In the hippocampal p...

journal_title：Neuroscience research

authors： Kim DS,Yoo KY,Hwang IK,Jung JY,Won MH,Choi SY,Kwon OS,Seo JH,Kang TC

更新日期：2005-01-01 00:00:00

abstract：:Efferent neurons to the cochlea in the guinea pig were observed in the superior olivary complex and ventral lateral lemniscal nuclei after injection of WGA-HRP into the cochlea via the round window. Of HRP-labeled nerve cells found in the brainstem, about 60% and 10% were located in the ipsilateral lateral superior ol...

journal_title：Neuroscience research

authors： Tokunaga A

更新日期：1988-10-01 00:00:00

abstract：:Over the last few decades, motor imagery has attracted the attention of researchers as a prototypical example of 'embodied cognition' and also as a basis for neuro-rehabilitation and brain-machine interfaces. The current definition of motor imagery is widely accepted, but it is important to note that various abilities...

journal_title：Neuroscience research

authors： Hanakawa T

更新日期：2016-03-01 00:00:00

abstract：:Many different kinds of voltage-gated ion channels (Na+ channels, K+ channels, Ca2+ channels) exist at neuronal dendrites. Integration of dendritic electric signals (excitatory postsynaptic potentials (EPSPs), inhibitory postsynaptic potentials (IPSPs) and action potentials) and/or non-electric signals (Ca2+ and secon...

journal_title：Neuroscience research

authors： Takagi H

更新日期：2000-07-01 00:00:00

abstract：:1-methyl-4-phenylpyridinium ion (MPP(+)), an inhibitor of mitochondrial complex I, has been widely used as a neurotoxin because it elicits a severe Parkinson's disease-like syndrome with elevation of intracellular reactive oxygen species (ROS) level and apoptotic death. Salvianic acid A (SA), isolated from the Chinese...

journal_title：Neuroscience research

authors： Wang XJ,Xu JX

更新日期：2005-02-01 00:00:00

abstract：:The responses of slice-cultured Purkinje cells to trans-DL-1-amino-1,3-cyclopentanedicarboxylic acid (t-ACPD) were examined by intracellular recording techniques and fura-2 microfluorometry. Bath-application of t-ACPD (100 microM, 30 s), a selective agonist of metabotropic glutamate receptors (mGluRs), to Purkinje cel...

journal_title：Neuroscience research

authors： Vranesic I,Staub C,Knöpfel T

更新日期：1993-03-01 00:00:00

abstract：:A group of brain acid-soluble proteins (BASPs) is preliminarily characterized. In some respects BASPs are similar to high mobility group (HMG) proteins, but in contrast to HMG, all BASPs are very acidic (pI 4.4-4.6) and show abnormal mobility during SDS-PAGE electrophoresis. BASP2-1 and BASP2-2 are identified as the t...

journal_title：Neuroscience research

authors： Mosevitsky MI,Novitskaya VA,Plekhanov AYu,Skladchikova GYu

更新日期：1994-03-01 00:00:00

abstract：:Nandrolone is the most popular compound that are mainly abused. Experimental studies have reported that administration of nandrolone affects cognitive performance. So, the aim of this study is to evaluate the effect of nandrolone on spatial localization and synaptic plasticity of male adolescent rats. Experimantal gro...

journal_title：Neuroscience research

authors： Salimi Z,Khajehpour L,Moradpour F,Moazedi AA,Pourmotabbed A,Zarei F

更新日期：2020-09-01 00:00:00

abstract：:Concurrent eye and hand movements toward a common visual target require different motor programs based on identical visual input. We used event-related brain potentials (ERP) to determine if and when the processing of the visual target differs for the two motor systems. The N2, an index for target evaluation, was more...

journal_title：Neuroscience research

authors： Wehrspaun CC,Pfabigan DM,Sailer U

更新日期：2013-09-01 00:00:00

abstract：:Almost all organisms on Earth have an internal biological clock, known as the circadian clock. This clock system drives robust oscillations in metabolism, physiology, and behavior, such as hormone secretions, blood pressure, and sleep/wake cycles, with a period of approximately 24h. In mammals, circadian rhythms are g...

journal_title：Neuroscience research

authors： Yamaguchi Y

更新日期：2018-04-01 00:00:00

abstract：:Trauma to the spinal cord initiates a series of cellular and biochemical processes that damage both neurons and glia. TGF-beta and its receptors are expressed around the injury site following a spinal cord injury. Here, we report that the intrathecal administration of a neutralizing antibody to TGF-beta1 in rats with ...

journal_title：Neuroscience research

authors： Kohta M,Kohmura E,Yamashita T

更新日期：2009-12-01 00:00:00

abstract：:Damage to the central nervous system (CNS) leads to disruption of the vascular network, causing vascular dysfunction. Vascular dysfunction is the major event in the pathogenesis of CNS diseases and is closely associated with the severity of neuronal dysfunction. The suppression of vascular dysfunction has been conside...

journal_title：Neuroscience research

authors： Muramatsu R,Yamashita T

更新日期：2014-04-01 00:00:00

abstract：:Distribution of the delta- and epsilon-subspecies of protein kinase C (PKC) in rat central nervous tissues was semiquantitated by an immunoblot analysis. The epsilon-subspecies, which is expressed predominantly in the brain, was abundant in hippocampus and cerebral cortex among rat brain areas, whereas the delta-subsp...

journal_title：Neuroscience research

authors： Matsushima S,Nakamura S

更新日期：1994-05-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) is a recently identified member of the secretin/vasoactive intestinal polypeptide (VIP) family. There are at least two types of receptor for PACAP: type I (PACAPR), which specifically binds PACAP; and type II (VIP/PACAPR), which binds both PACAP and VIP. The l...

journal_title：Neuroscience research

authors： Shioda S,Shuto Y,Somogyvari-Vigh A,Legradi G,Onda H,Coy DH,Nakajo S,Arimura A

更新日期：1997-08-01 00:00:00

abstract：:Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic injury. In the present study, we examined the possibility that the n...

journal_title：Neuroscience research

authors： Candelario-Jalil E,Alvarez D,Merino N,León OS

更新日期：2003-10-01 00:00:00

abstract：:We carried out voltage-sensitive dye imaging of the guinea pig auditory cortex to determine whether the ongoing and spontaneous activities of the cortex exhibit spatial coherence reflecting the tonotopic organization of the cortex. We used independent component analysis and a signal-plus-noise model to extract ongoing...

journal_title：Neuroscience research

authors： Yoshida T,Sakagami M,Katura T,Yamazaki K,Tanaka S,Iwamoto M,Tanaka N

更新日期：2008-05-01 00:00:00

abstract：:The A5 is an unique membrane protein that is expressed in the neurons of the visual system and general somatic sensory system of Xenopus laevis. We cultured retinal explants or trigeminal ganglion neurons on the monolayers of A5-expressing line cells obtained by transfection with the cDNA, and found that the A5-expres...

journal_title：Neuroscience research

authors： Hirata T,Takagi S,Fujisawa H

更新日期：1993-07-01 00:00:00

abstract：:Dopamine is a major neurotransmitter in the carotid body of several animal species and its functional role at the level of peripheral arterial chemoreflex pathway is attributed to the presence of the dopamine D2-receptors. We present evidence that the dopamine D1-receptor mRNA is also expressed in the carotid body of ...

journal_title：Neuroscience research

authors： Bairam A,Frenette J,Dauphin C,Carroll JL,Khandjian EW

更新日期：1998-06-01 00:00:00

abstract：:Forebrain heat shock protein 70 (HSP70) immunohistochemical reactivity was investigated in rats subjected to gamma knife irradiation focusing on the right caudate putamen nucleus. The forebrain sections of all experimental animals were processed with anti-HSP70 antiserum and then by avidin-biotin peroxidase complex im...

journal_title：Neuroscience research

authors： Rao ZR,Ge X,Qiou JY,Yang T,Duan L,Ju G

更新日期：2000-10-01 00:00:00

abstract：:To investigate how motor programs can be modified by sensory inputs we recorded kinematic and EMG patterns from normal human subjects performing well-practised wrist flexion movements in response to an auditory tone. On random trials unexpected wrist perturbations were introduced at varying times after the signal to m...

journal_title：Neuroscience research

authors： Hayashi R,Becker WJ,Lee RG

更新日期：1990-06-01 00:00:00

abstract：:Axonal transport is the specialized and well-developed intracellular transport system for regulated and/or long-distance transport based on generalized cellular machineries. Among them, slow axonal transport conveys cytoplasmic proteins. The motor molecule, the nature of transporting complex and the transport regulati...

journal_title：Neuroscience research

authors： Terada S

更新日期：2003-12-01 00:00:00

abstract：:This experiment tested the effect of haloperidol on the sympathetic and thermogenic effects induced by orexin A. The firing rates of the sympathetic nerves to interscapular brown adipose tissue (IBAT), along with IBAT and colonic temperatures and heart rate were monitored in urethane-anesthetized male Sprague-Dawley r...

journal_title：Neuroscience research

authors： Monda M,Viggiano A,De Luca V

更新日期：2003-01-01 00:00:00

abstract：:Communication in the central nervous system (CNS) occurs through initiation and propagation of action potentials at excitable domains along axons. Action potentials generated at the axon initial segment (AIS) are regenerated at nodes of Ranvier through the process of saltatory conduction. Proper formation and maintena...

journal_title：Neuroscience research

authors： Griggs RB,Yermakov LM,Susuki K

更新日期：2017-03-01 00:00:00

abstract：:Huntington's disease (HD) is caused due to expansion of CAG repeats in the gene huntingtin (Htt). Adaptor protein Grb2, involved in Ras-MAP kinase pathway, is a known interactor of Htt. Mutant Htt-Grb2 interaction reduces Ras-MAPK signaling in HD models. In normal cells Grb2 forms Grb2-Sos1-Gab1 complex through its N-...

journal_title：Neuroscience research

authors： Baksi S,Basu S,Mukhopadhyay D

更新日期：2014-10-01 00:00:00