Superior olivary and lateral lemniscal neurons projecting to the cochlea in the guinea pig.

abstract：:Event-related potentials (ERPs) during an auditory discrimination task were recorded both on the surface and at a depth of the auditory cortex in rats. Ten-kilohertz rare and 5-kHz frequent tones were used with the probabilities of 0.2 and 0.8. Lever pressing within 2 s, following the onset of the rare tone, was rewar...

journal_title：Neuroscience research

authors： Iwanami A,Shinba T,Sumi M,Ozawa N,Yamamoto K

更新日期：1994-11-01 00:00:00

abstract：:Metabolism of amyloid-beta peptide (Abeta) is closely associated with the pathology and etiology of Alzheimer's disease (AD). Since neprilysin is the only rate-limiting catabolic peptidase proven by reverse genetics to participate in Abeta metabolism in vivo, we performed detailed immunohistochemical analysis of nepri...

journal_title：Neuroscience research

authors： Fukami S,Watanabe K,Iwata N,Haraoka J,Lu B,Gerard NP,Gerard C,Fraser P,Westaway D,St George-Hyslop P,Saido TC

更新日期：2002-05-01 00:00:00

abstract：:Pathological gambling (PG) is a non-substance based addiction that shares many behavioral and neural features with substance based addictions. However, in PG behavioral and neural changes are unlikely to be confounded by effects of acute or chronic drug exposure. Changes in reward based decision-making in particular i...

journal_title：Neuroscience research

authors： Wiehler A,Peters J

更新日期：2015-01-01 00:00:00

abstract：:Recently, we have found novel mammalian tachykinins, neurokinin alpha and beta isolated from porcine spinal cord, whose chemical structures are similar to those of substance P or kassinin. In the present study, we describe a specific assay system for neurokinin alpha and beta by combining HPLC and radioimmunoassay. We...

journal_title：Neuroscience research

authors： Kanazawa I,Ogawa T,Kimura S,Munekata E

更新日期：1984-12-01 00:00:00

abstract：:Many forms of psychopathology and/or psychiatric illness can occur through the pathways of altered environmental sensitivity, impulsivity, social functioning, and anxious responding. While these traits are also heritable, environmental conditions are known to play a critical role. The genetic factors that contribute t...

journal_title：Neuroscience research

authors： Driscoll CA,Barr CS

更新日期：2016-01-01 00:00:00

abstract：:The magnitude of long-term potentiation (LTP) was re-examined for monosynaptic transmission between mossy fibers and CA3 neurons in thin sections of the hippocampus of the guinea pig. Although an initial negative deflection in the field potential showed apparent short-term potentiation, this deflection was concluded t...

journal_title：Neuroscience research

authors： Higashima M,Yamamoto C

更新日期：1986-09-01 00:00:00

abstract：:Close relationships between the nervous system and immune systems at molecular levels have now become evident. Receptors for CDF/LIF and CNTF, i.e., factors which play important roles in the nervous system, share a close structural similarity to those for IL-6, which is a molecule acting in the immune system. Receptor...

journal_title：Neuroscience research

authors： Yamamori T,Sarai A

更新日期：1992-11-01 00:00:00

abstract：:The contribution of intrinsic balance control factors to fall mechanisms has received little investigation in studies on occupational accidents. The aim of this study was to assess whether postural regulation in falling workers might have specificities in terms of sensorimotor strategies and neuromuscular responses to...

journal_title：Neuroscience research

authors： Vouriot A,Gauchard GC,Chau N,Benamghar L,Lepori ML,Mur JM,Perrin PP

更新日期：2004-03-01 00:00:00

abstract：:Properties of the Ca2+ -activated K+ current (I[K(Ca)]) were investigated in bipolar cells isolated from the goldfish retina. Pharmacological experiments and single channel current recordings demonstrated that I[K(Ca)] represented currents through BK channels, which were confined mostly to the presynaptic terminal. Th...

journal_title：Neuroscience research

authors： Sakaba T,Ishikane H,Tachibana M

更新日期：1997-03-01 00:00:00

abstract：:To elucidate the molecular mechanisms that regulate the maturation of action potential, we began by examining voltage-dependent K+ currents, known to contribute to the maturation of action potential, of developing granule cells in mouse cerebellar microexplant cultures. The migration of developing granule cells in thi...

journal_title：Neuroscience research

authors： Wakazono Y,Kurahashi T,Nakahira K,Nagata I,Takayama C,Inoue Y,Kaneko A,Ikenaka K

更新日期：1997-12-01 00:00:00

abstract：:The neurodegenerative process in Parkinson's disease (PD) is accompanied by the presence of a neuroinflammatory response, which has been suggested as one of the principal components involved in PD progression. In this report we assessed the inflammatory potential of alpha-synuclein, a protein central to PD pathogenesi...

journal_title：Neuroscience research

authors： Alvarez-Erviti L,Couch Y,Richardson J,Cooper JM,Wood MJ

更新日期：2011-04-01 00:00:00

abstract：:Interleukin-6 (IL-6, human recombinant) promoted the survival of catecholaminergic neurons from fetal and postnatal rat midbrains as assessed by an immunohistochemical staining for tyrosine hydroxylase (TH) in culture using a chemically defined medium. The maximal dose of IL-6 for the cell survival of postnatal P15 ra...

journal_title：Neuroscience research

authors： Kushima Y,Hama T,Hatanaka H

更新日期：1992-05-01 00:00:00

abstract：:Using Mayahara's method, the distribution of K(+)-dependent p-nitrophenylphosphatase activity was examined electron microscopically in the synaptic regions of the cerebral cortex of 10, 15 and 60-day-old Wistar rats. The enzyme achieved gradually its characteristic localization and uniform distribution. The main devel...

journal_title：Neuroscience research

authors： Dolapchieva S

更新日期：1996-02-01 00:00:00

abstract：:It has previously been shown that when a target is moved, cats can change the direction of ongoing target-reaching with brief latency suggesting a tectal relay. Switching of target-reaching has now been investigated after spinal lesions: (1) dorsally in C5 interrupting cortico- (CS) and rubrospinal (RS) fibres to fore...

journal_title：Neuroscience research

authors： Alstermark B,Górska T,Lundberg A,Pettersson LG,Walkowska M

更新日期：1987-10-01 00:00:00

abstract：:Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic injury. In the present study, we examined the possibility that the n...

journal_title：Neuroscience research

authors： Candelario-Jalil E,Alvarez D,Merino N,León OS

更新日期：2003-10-01 00:00:00

abstract：:A multibarreled glass-coated tungsten microelectrode suitable for single-unit recording and iontophoresis in chronically behaving animals is described. The microelectrode was stiff enough to pass through the dura matter of behaving monkeys, and can be applied as a microiontophoretic electrode. The electrode is easy to...

journal_title：Neuroscience research

authors： Li BM,Mei ZT,Kubota K

更新日期：1990-07-01 00:00:00

abstract：:Dopamine is a major neurotransmitter in the carotid body of several animal species and its functional role at the level of peripheral arterial chemoreflex pathway is attributed to the presence of the dopamine D2-receptors. We present evidence that the dopamine D1-receptor mRNA is also expressed in the carotid body of ...

journal_title：Neuroscience research

authors： Bairam A,Frenette J,Dauphin C,Carroll JL,Khandjian EW

更新日期：1998-06-01 00:00:00

abstract：:The cyclic nucleotides perform a variety of roles in the formation and remodeling of the neuronal interaction. The membrane microdomain called "raft" has been paid much attention, for this domain contains many signal-transducing molecules including trimeric G proteins and cytoskeletal proteins. The raft domain is reco...

journal_title：Neuroscience research

authors： Noyama K,Maekawa S

更新日期：2003-02-01 00:00:00

abstract：:Subcortical vascular dementia (SVD) is a small vessel disease with dementia that exhibits relatively uniform clinical and pathological features and constitutes approximately half of vascular dementia (VaD) cases. This subtype is further classified into Binswanger's disease and multiple lacunar infarctions. The former ...

journal_title：Neuroscience research

authors： Tomimoto H

更新日期：2011-11-01 00:00:00

abstract：:In rats with a unilateral 6-hydroxydopamine (6-OHDA)-induced lesion in the nigrostriatal fibers, methamphetamine (3 mg/kg, i.p.) induced Fos-like immunoreactivity (FLI), which was inhibited by pretreatment with N-methyl-D-aspartate antagonist MK-801 (1 mg/kg, i.p.), not only in the medial striatum contralateral to the...

journal_title：Neuroscience research

authors： Ishida Y,Todaka K,Kuwahara I,Nakane H,Ishizuka Y,Nishimori T,Mitsuyama Y

更新日期：1998-04-01 00:00:00

abstract：:Fatty acid-binding protein 3 (Fabp3) is an intracellular lipid trafficking protein that mediates energy metabolism and long-chain fatty acid-related signaling. Fabp3 is expressed in the spiral ganglion neurons and supporting cells of the organ of Corti. However, it is unclear what role Fabp3 plays in the cochlea. Here...

journal_title：Neuroscience research

authors： Suzuki J,Oshima T,Yoshida N,Kimura R,Takata Y,Owada Y,Kobayashi T,Katori Y,Osumi N

更新日期：2014-04-01 00:00:00

abstract：:Xenopus oocytes injected with messenger RNA extracted from rat brain are induced to acquire a variety of neurotransmitter receptors and voltage-operated membrane channels. Activation of the receptors to serotonin, acetylcholine (muscarinic) and glutamate elicits oscillatory membrane currents carried by chloride ions. ...

journal_title：Neuroscience research

authors： Parker I,Gundersen CB,Miledi R

更新日期：1985-08-01 00:00:00

abstract：:Nerve growth factor (NGF)-like immunoreactivity was demonstrated in the rat pituitary intermediate lobe by indirect immunofluorescence method using antisera specific to beta-NGF isolated from adult male mouse submaxillary salivary gland. Co-culture of frozen or fresh intermediate lobes with newborn rat superior cervic...

journal_title：Neuroscience research

authors： Soinila S,Lakshmanan J,Lahtinen T

更新日期：1988-12-01 00:00:00

abstract：:Alzheimer's disease (AD) is a chronic and fatal disease, in which neuronal damage at its late stage cannot be easily reversed. Because AD progression is caused by multiple factors including diverse cellular processes, studies on AD pathogenesis at the molecular and cellular level are challenging. Based on the lessons ...

journal_title：Neuroscience research

authors： Chun H,Lee CJ

更新日期：2018-01-01 00:00:00

abstract：:In previous studies we provided evidence for changes in prolactin (PRL) receptor levels in the male rat brain after continuously infusing morphine using subcutaneously implanted miniosmotic pumps. In this work we have studied the binding of PRL in the male rat brain following morphine administration by both subcutaneo...

journal_title：Neuroscience research

authors： Lai Z,Zhai Q,Liu Z,Roos P,Nyberg F

更新日期：1995-10-01 00:00:00

abstract：:We have been advocating cognitive developmental robotics to obtain new insight into the development of human cognitive functions by utilizing synthetic and constructive approaches. Among the different emotional functions, empathy is difficult to model, but essential for robots to be social agents in our society. In my...

journal_title：Neuroscience research

authors： Asada M

更新日期：2015-01-01 00:00:00

abstract：:We examined the number and size of motoneurons and myelinated nerve fibers innervating the medial gastrocnemius (MG) muscle in the hindlimb of rats that were subjected to swimming for 10 months (30 min, 3 days/week) from 17 to 27 months of age. The number of MG motoneurons in exercised aged rats was slightly, but not ...

journal_title：Neuroscience research

authors： Kanda K,Hashizume K

更新日期：1998-05-01 00:00:00

abstract：:According to the amyloid hypothesis for the pathogenesis of Alzheimer's disease (AD), amyloid beta peptide (Abeta) directly affects neurons, leading to neurodegeneration and tau phosphorylation, followed by the production of paired helical filaments (PHF) in neurofibrillary tangles (NFT). To analyze the relationship b...

journal_title：Neuroscience research

authors： Takashima A,Honda T,Yasutake K,Michel G,Murayama O,Murayama M,Ishiguro K,Yamaguchi H

更新日期：1998-08-01 00:00:00

abstract：:This experiment tested the effect of haloperidol on the sympathetic and thermogenic effects induced by orexin A. The firing rates of the sympathetic nerves to interscapular brown adipose tissue (IBAT), along with IBAT and colonic temperatures and heart rate were monitored in urethane-anesthetized male Sprague-Dawley r...

journal_title：Neuroscience research

authors： Monda M,Viggiano A,De Luca V

更新日期：2003-01-01 00:00:00

abstract：:Diazepam binding inhibitor (DBI), a putative endogenous polypeptide ligand for benzodiazepine (BZD) receptors, has been shown to act as an inverse BZD receptor agonist in the brain. We previously suggested that the social isolation stress-induced decrease in pentobarbital sleeping time in mice was partly due to an inc...

journal_title：Neuroscience research

authors： Dong E,Matsumoto K,Tohda M,Kaneko Y,Watanabe H

更新日期：1999-03-01 00:00:00