Abstract：
:Event-related potentials (ERPs) during an auditory discrimination task were recorded both on the surface and at a depth of the auditory cortex in rats. Ten-kilohertz rare and 5-kHz frequent tones were used with the probabilities of 0.2 and 0.8. Lever pressing within 2 s, following the onset of the rare tone, was rewarded with food paste. In the performing condition, the surface ERPs for the rare tones consisted of P30, N50, P80, N130, and P290 components. Only the surface P30 and N50 showed a polarity reversal at the intracortical electrode, suggesting that these components are generated in the auditory cortex. The P290 was elicited in the performing condition but not in the resting condition, showing its task-relevancy. These results suggest that auditory ERPs similar to those in humans can be recorded in rats during an active discrimination task.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Iwanami A,Shinba T,Sumi M,Ozawa N,Yamamoto Kdoi
10.1016/0168-0102(94)90073-6subject
Has Abstractpub_date
1994-11-01 00:00:00pages
103-6issue
1eissn
0168-0102issn
1872-8111pii
0168-0102(94)90073-6journal_volume
21pub_type
杂志文章abstract：:Maternal stress, viral infection, and obstetric complications, which trigger cytokine signaling, are hypothesized to be involved in schizophrenia and its related disorders. The etiologic contribution of individual cytokines to such psychiatric disorders, however, remains to be evaluated. To estimate the impact of peri...
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