Abstract：
:Vestibular nuclear neurons that mediate horizontal canal signals to the ipsilateral medial rectus motoneurons were explored in anesthetized and decerebrate rabbits. These neurons were identified by four criteria: (1) they were activated monosynaptically by ipsilateral vestibular nerve stimulation and (2) antidromically from the oculomotor nucleus region, while they were inhibited by (3) direct floccular stimulation and (4) ipsilateral retinal stimulation that activated floccular Purkinje cells via a climbing fiber afferent pathway. Neurons fulfilling these criteria were found in two anatomically different regions, i.e. the rostrolateral part of the medial vestibular nucleus and in the ventral part of the lateral vestibular nucleus. In decerebrate rabbits, neurons in both loci responded to horizontal rotation of the whole body with the type I pattern (excited by ipsilateral rotation). These results suggest that horizontal canal signals are conveyed to ipsilateral medial rectus motoneurons by two separate groups of vestibular nuclear neurons which may play different roles in the vestibulo-ocular reflex.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Kawaguchi Ydoi
10.1016/0168-0102(85)90016-1subject
Has Abstractpub_date
1985-08-01 00:00:00pages
434-46issue
6eissn
0168-0102issn
1872-8111pii
0168-0102(85)90016-1journal_volume
2pub_type
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