Roles of ion channels in EPSP integration at neuronal dendrites.

abstract：:To elucidate the interaction between nitric oxide (NO) and substance P (SP) in neurogenic inflammatory responses, we measured the change in the degree of Evans blue leakage and NO levels in perfusate from the subcutaneous space in the rat instep following noxious heat stimulation (47 degrees C for 30 min). Furthermore...

journal_title：Neuroscience research

authors： Yonehara N,Yoshimura M

更新日期：2000-01-01 00:00:00

abstract：:NAP-22, a neuronal tissue-enriched acidic membrane protein, is a Ca(2+)-dependent calmodulin binding protein and has similar biochemical characteristics to GAP-43 (neuromodulin). Recent biochemical studies have demonstrated that NAP-22 localizes in the membrane raft domain with a cholesterol-dependent manner. Since th...

journal_title：Neuroscience research

authors： Kashihara M,Miyata S,Kumanogoh H,Funatsu N,Matsunaga W,Kiyohara T,Sokawa Y,Maekawa S

更新日期：2000-08-01 00:00:00

abstract：:The aim of the present study was to investigate whether increased concentrations of lactic acid and potassium chloride (KCl) in contralateral muscles can influence the sensitivity of primary and secondary muscle spindle afferents (MSAs) from ipsilateral extensor and flexor muscles. The experiments were performed on 7 ...

journal_title：Neuroscience research

authors： Djupsjöbacka M,Johansson H,Bergenheim M,Sjölander P

更新日期：1995-02-01 00:00:00

abstract：:One important aspect of empathy is a "resonance mechanism", which includes emotional cue detection, facial mimicry (measured by electromyography, EMG) and a specific cortical response. This study explored the convergence of these three measures of affective empathy. The twenty students who took part in the study were ...

journal_title：Neuroscience research

authors： Balconi M,Bortolotti A,Gonzaga L

更新日期：2011-11-01 00:00:00

abstract：:Efferent neurons to the cochlea in the guinea pig were observed in the superior olivary complex and ventral lateral lemniscal nuclei after injection of WGA-HRP into the cochlea via the round window. Of HRP-labeled nerve cells found in the brainstem, about 60% and 10% were located in the ipsilateral lateral superior ol...

journal_title：Neuroscience research

authors： Tokunaga A

更新日期：1988-10-01 00:00:00

abstract：:The coexistence of varying combinations of substance P (SP), somatostatin (SOM), thyrotropin-releasing hormone (TRH) and met-enkephalin-Arg-Gly-Leu (ENK) with 5-hydroxytryptamine (5-HT) as semiquantitatively revealed by immunocytochemistry in neuronal perikarya of the raphe pallidus et obscurus in the guinea-pig was a...

journal_title：Neuroscience research

authors： Chiba T,Masuko S

更新日期：1989-10-01 00:00:00

abstract：:TDP-43 pathology in motor neurons is a hallmark of ALS. In addition, the reduced expression of an RNA editing enzyme, adenosine deaminase acting on RNA 2 (ADAR2), increases the expression of GluA2 with an unedited Q/R site in the motor neurons of patients with sporadic ALS. As the occurrence of these two disease-speci...

journal_title：Neuroscience research

authors： Yamashita T,Hideyama T,Teramoto S,Kwak S

更新日期：2012-06-01 00:00:00

abstract：:A glial cell line designated as B2 was generated from primary cultures of oligodendrocytes/astrocytes isolated from an adult BALB/c mouse brain and maintained for over 1 year. Phenotypic characteristics of B2 cells were investigated by immunolabeling with cell type-specific markers for oligodendrocytes (O4 and galacto...

journal_title：Neuroscience research

authors： Satoh J,Tabira T,Kim SU

更新日期：1994-08-01 00:00:00

abstract：:The actin cytoskeleton plays a critical role in the cellular morphological changes. Its organization is essential for neurite extension and synaptogenesis under the processes of neuronal development. Recently, neural Wiskott-Aldrich syndrome protein (N-WASP) and WASP family verprolin-homologous protein (WAVE) have bee...

journal_title：Neuroscience research

authors： Tsuchiya D,Kitamura Y,Takata K,Sugisaki T,Taniguchi T,Uemura K,Miki H,Takenawa T,Shimohama S

更新日期：2006-12-01 00:00:00

abstract：:To clarify a role of neuronal nitric oxide in neurovascular coupling, we performed cerebral blood flow (CBF) and cerebral metabolic rate of glucose (CMR(glc)) measurements with positron emission tomography in somatosensory-stimulated cats using a specific neuronal nitric oxide synthase inhibitor, 7-nitroindazole (7-NI...

journal_title：Neuroscience research

authors： Hayashi T,Katsumi Y,Mukai T,Inoue M,Nagahama Y,Oyanagi C,Yamauchi H,Shibasaki H,Fukuyama H

更新日期：2002-10-01 00:00:00

abstract：:Interleukin-6 (IL-6, human recombinant) promoted the survival of catecholaminergic neurons from fetal and postnatal rat midbrains as assessed by an immunohistochemical staining for tyrosine hydroxylase (TH) in culture using a chemically defined medium. The maximal dose of IL-6 for the cell survival of postnatal P15 ra...

journal_title：Neuroscience research

authors： Kushima Y,Hama T,Hatanaka H

更新日期：1992-05-01 00:00:00

abstract：:Dynamic properties of horizontal vestibulo-ocular reflex (VOR) and optokinetic response (OKR) were studied in mice. The VOR was examined in the dark (VORD), in the light (VORL) and in the condition in which most of the visual field moves synchronously with the head motion (VORF). A mouse and/or a surrounding screen wi...

journal_title：Neuroscience research

authors： Iwashita M,Kanai R,Funabiki K,Matsuda K,Hirano T

更新日期：2001-03-01 00:00:00

abstract：:Visual-spatial navigation in familiar and unfamiliar environments is an essential requirement of daily life. Animal studies indicated the importance of the hippocampus for navigation. Neuroimaging studies demonstrated gender difference or strategies dependent difference of neural substrates for navigation. Using funct...

journal_title：Neuroscience research

authors： Ohnishi T,Matsuda H,Hirakata M,Ugawa Y

更新日期：2006-08-01 00:00:00

abstract：:Mutations in the dynamin family GTPase OPA1 are reportedly the cause of autosomal dominant optic atrophy, the most frequently occurring form of hereditary optic neuropathy. But although the involvement of structural abnormalities of the enzyme in this neurodegenerative disease is clear, little is known about the cell ...

journal_title：Neuroscience research

authors： Misaka T,Murate M,Fujimoto K,Kubo Y

更新日期：2006-06-01 00:00:00

abstract：:Long-term depression at parallel fiber-Purkinje cell synapses plays a principal role in learning in the cerebellum, which acts as a supervised learning machine. Recent experiments demonstrate various forms of synaptic plasticity at different sites within the cerebellum. In this article, we take into consideration syna...

journal_title：Neuroscience research

authors： Yamazaki T,Lennon W

更新日期：2019-11-01 00:00:00

abstract：:The radioprotective effect of herb epimedium (or yin yang huo) extract (5 g/kg, oral administration daily for 4 weeks) on neurogenesis and cognition after acute radiation exposure with 5.5 Gy was evaluated in Balb/c mice by behavioral tests and immunohistochemical study. The results indicated that epimedium extract co...

journal_title：Neuroscience research

authors： Wang SW,Ren BX,Qian F,Luo XZ,Tang X,Peng XC,Huang JR,Tang FR

更新日期：2019-08-01 00:00:00

abstract：:Executive Functions (EFs) involve a set of high cognitive abilities impairment which have been successfully related to a redox omeostasis imbalance in several psychiatric disorders. Firstly, we aimed to investigate the relationship between executive functioning and some oxidative metabolism parameters in Peripheral Bl...

journal_title：Neuroscience research

authors： Pesce M,Rizzuto A,La Fratta I,Tatangelo R,Campagna G,Iannasso M,Ferrone A,Franceschelli S,Speranza L,Patruno A,De Lutiis MA,Felaco M,Grilli A

更新日期：2016-05-01 00:00:00

abstract：:We simulated brain lesions in mean diffusivity (MD) and fractional anisotropy (FA) images of healthy subjects to evaluate the performance of voxel-based analysis (VBA) with SPM2. We increased MD and decreased FA, simulating the most typical abnormalities in brain pathologies, in the superior longitudinal fasciculus (S...

journal_title：Neuroscience research

authors： Hiltunen J,Seppä M,Hari R

更新日期：2011-12-01 00:00:00

abstract：:DJ-1 is a multifunctional protein linked to recessively inherited Parkinson's disease (PD) due to loss of function mutations. Among its activities is anti-oxidant property leading to cytoprotection under oxidative stress conditions. A key effector of oxidant-induced cell death is the MAP3 kinase apoptosis signal-regul...

journal_title：Neuroscience research

authors： Im JY,Lee KW,Junn E,Mouradian MM

更新日期：2010-07-01 00:00:00

abstract：:Xenopus oocytes injected with messenger RNA extracted from rat brain are induced to acquire a variety of neurotransmitter receptors and voltage-operated membrane channels. Activation of the receptors to serotonin, acetylcholine (muscarinic) and glutamate elicits oscillatory membrane currents carried by chloride ions. ...

journal_title：Neuroscience research

authors： Parker I,Gundersen CB,Miledi R

更新日期：1985-08-01 00:00:00

abstract：:Various heterotrimeric G protein betagamma subunits (Gbetagamma) are region-specifically expressed in brain where associated with "stress-axis", however, the role of Gbetagamma-mediated signaling in regulating stress is unknown. This study was designed to examine the changes of Gbetagamma expression and Gbetagamma-med...

journal_title：Neuroscience research

authors： Lee SY,Kang JS,Song GY,Myung CS

更新日期：2006-10-01 00:00:00

abstract：UNLABELLED:Angiotensin II receptors (Ang II), classified into AT1 and AT2 subtypes, are located in different regions of the central nervous system, including the cardiovascular control centers in the medulla oblongata. We previously reported the role of Ang II AT1 receptors within the medulla on cardiovascular response...

journal_title：Neuroscience research

authors： Tedesco A,Ally A

更新日期：2009-08-01 00:00:00

abstract：:The neural and molecular mechanisms underlying food preference have been poorly understood. We previously showed that Bifidobacterium infantis (B. infantis), a well-known probiotic bacterium, extends the lifespan of Caenorhabditis elegans (C. elegans) compared with a standard food, Escherichia coli (E. coli) OP50. In ...

journal_title：Neuroscience research

authors： Sun S,Ohta A,Kuhara A,Nishikawa Y,Kage-Nakadai E

更新日期：2020-01-01 00:00:00

abstract：:The entopeduncular nucleus (EPN) is one of the major output nuclei of the basal ganglia in rodents. Previous studies have divided it into rostral and caudal halves, with the former containing somatostatin (SOM)-immunoreactive neurons and the latter dominated by parvalbumin (PV)-containing neurons, respectively. Howeve...

journal_title：Neuroscience research

authors： Miyamoto Y,Fukuda T

更新日期：2015-05-01 00:00:00

abstract：:Most imaging studies of the enteric nervous system (ENS) that regulates the function of the gastrointestinal tract are so far performed using preparations isolated from animals, thus hindering the understanding of the ENS function in vivo. Here we report a method for imaging the ENS cellular network activity in living...

journal_title：Neuroscience research

authors： Motegi Y,Sato M,Horiguchi K,Ohkura M,Gengyo-Ando K,Ikegaya Y,Fusamae Y,Hongo Y,Suzuki M,Ogawa K,Takaki M,Nakai J

更新日期：2020-02-01 00:00:00

abstract：:In 15 cats with implantations of crystalline HRP-WGA in the cerebellar nuclei and tetramethylbenzidine histochemistry, the pontine nuclei were carefully examined for presence of retrogradely labelled cells. Findings in the nucleus reticularis tegmenti pontis and the inferior olive, both known to project to the cerebel...

journal_title：Neuroscience research

authors： Brodal P,Dietrichs E,Walberg F

更新日期：1986-11-01 00:00:00

abstract：:Epidemiological studies have shown that maternal infection during early pregnancy increases the risk of neurodevelopmental disorders (i.e., schizophrenia or autism) in offspring. Recently, diagnostic/stratification biomarkers for the maternal immune activation background in patients with neurodevelopmental disorders h...

journal_title：Neuroscience research

authors： Oh-Nishi A,Koga K,Maeda T,Suhara T

更新日期：2016-12-01 00:00:00

abstract：:In anesthetized and immobilized Japanese monkeys (Macaca fuscata), intraretinal conduction velocities of the ganglion cell axons were measured. The field potentials elicited by optic chiasm shocks consisted of fast and slow components with estimated conduction velocities of 1.19 and 0.72 m/s in recordings from the opt...

journal_title：Neuroscience research

authors： Fukuda Y,Watanabe M,Wakakuwa K,Sawai H,Morigiwa K

更新日期：1988-10-01 00:00:00

abstract：:We investigated the neural mechanisms underlying the ability to cope in atypical or novel situations using tools. We hypothesized that two cognitive components support this ability: adaptive coordination (for adapting to situational demands) and cognitive inhibition (for inhibiting the incongruent actions afforded by ...

journal_title：Neuroscience research

authors： Wakusawa K,Sugiura M,Sassa Y,Jeong H,Yomogida Y,Horie K,Sato S,Yokoyama H,Kure S,Takei N,Mori N,Kawashima R

更新日期：2015-01-01 00:00:00

abstract：:Angiotensin II (Ang II) receptors are located in different regions of the brain, particularly within the cardiovascular control centers in the brainstem. These Ang II receptors are divided into AT1 and AT2 subtypes. We investigated the role of AT1 receptor subtype within the rostral (RVLM) and caudal (CVLM) ventrolate...

journal_title：Neuroscience research

authors： Patel D,Böhlke M,Phattanarudee S,Kabadi S,Maher TJ,Ally A

更新日期：2008-03-01 00:00:00