Abstract：
:Reflex blinking provides a useful experimental tool for various functional studies on the peripheral and central nervous system, yet the neuronal circuitry underlying this reflex is not precisely known. In the present study, we investigated as to whether neurons in the reticular formation and rostral cervical spinal cord (C1) may be involved in the blink reflex in rats. To this end we investigated c-Fos expression in these areas following supraorbital nerve stimulation combined with retrograde tracing of gold conjugated horse radish peroxidase (Gold-HRP) from the superior colliculus. We observed many double labeled neurons in the parvocellular reticular nucleus, medullary reticular formation, and laminae IV and V of C1. Thus, these brain regions contain neurons that may be involved in blink reflexes as well as eye movements, because they both can be activated following peri-orbital stimulation and project to the superior colliculus. Consequently, we suggest that the medullary reticular formation and C1 region play a central role in the coordination of eye and eyelid movements during reflex blinking.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Smit AE,Buisseret P,Buisseret-Delmas C,De Zeeuw CI,VanderWerf F,Zerari-Mailly Fdoi
10.1016/j.neures.2006.08.005subject
Has Abstractpub_date
2006-12-01 00:00:00pages
363-71issue
4eissn
0168-0102issn
1872-8111pii
S0168-0102(06)00212-4journal_volume
56pub_type
杂志文章abstract：:Hypnosis often leads people to obey a suggestion of movement and to lose perceived voluntariness. This inexplicable phenomenon suggests that the state of the motor system may be altered by hypnosis; however, objective evidence for this is still lacking. Thus, we used transcranial magnetic stimulation of the primary mo...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2014.05.009
更新日期：2014-08-01 00:00:00
abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by progressive degeneration of motoneurons. We have demonstrated that hepatocyte growth factor (HGF) attenuates loss of both spinal and brainstem motoneurons of ALS model mice expressing mutated human SOD1(G93A) (G93A). This study was designed to ass...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2009.06.016
更新日期：2009-10-01 00:00:00
abstract：:Angiotensin II (Ang II) receptors are located in different regions of the brain, particularly within the cardiovascular control centers in the brainstem. These Ang II receptors are divided into AT1 and AT2 subtypes. We investigated the role of AT1 receptor subtype within the rostral (RVLM) and caudal (CVLM) ventrolate...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2007.12.002
更新日期：2008-03-01 00:00:00
abstract：:Disrupted-in-Schizophrenia 1 (DISC1) is a susceptibility gene for major mental illnesses, including bipolar disorder and schizophrenia. Although the roles of DISC1 in nervous system development and functions are increasingly recognized, pathophysiological mechanisms underlying a range of neuropsychiatric symptoms caus...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2011.05.014
更新日期：2011-09-01 00:00:00
abstract：:Spinal cord injury (SCI) is a serious condition often affecting young and healthy individuals around the world. Electro-acupuncture (EA) has been proven to contribute towards neurologic and functional recoveries in SCI, but the underlying mechanism remains largely unknown especially regarding neural specific proteins ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2010.04.012
更新日期：2010-08-01 00:00:00
abstract：:The hippocampus communicates with the neocortex via the entorhinal cortex and is thought to be critically involved in the consolidation of memories. This paper contains in vivo evidence of a projection from the hippocampal area CA1 to the entorhinal cortex. Current theories of memory formation suggest that the backpro...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2005.06.009
更新日期：2005-10-01 00:00:00
abstract：:Short-interval intracortical inhibition (SICI) acting on the first dorsal interosseus was measured using paired-pulse transcranial magnetic stimulation (interstimulus interval=2ms) in samples of young and healthy older subjects and correlated with manual dexterity measured with the Purdue Pegboard test and two isometr...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2011.04.004
更新日期：2011-08-01 00:00:00
abstract：:Post-traumatic stress disorder (PTSD) is an anxiety disorder that occurs following an unexpected exposure to a severe psychological event. A history of a brief trauma is reported to affect a risk for future PTSD development; however, little is known about the mechanisms by which a previous trauma exposure drives the s...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2015.02.001
更新日期：2015-06-01 00:00:00
abstract：:To investigate how motor programs can be modified by sensory inputs we recorded kinematic and EMG patterns from normal human subjects performing well-practised wrist flexion movements in response to an auditory tone. On random trials unexpected wrist perturbations were introduced at varying times after the signal to m...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(90)90062-j
更新日期：1990-06-01 00:00:00
abstract：:Development of neurofibrillary tangles (NFTs) is a pathological hallmark in various neurodegenerative disorders including Alzheimer's disease (AD). Recently, we identified a granular tau oligomer having a pre-filamentous structure. To determine the role of this oligomer in NFT formation, we quantified the amount of gr...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2005.11.009
更新日期：2006-03-01 00:00:00
abstract：:The role of cholinergic basal forebrain inputs to cerebral cortex in regulating regional nerve growth factor (NGF) secretion was examined in adult (4-6 months) and aged (29-31 months) rats. Halothane-anesthetized rats received unilateral electrical stimulation of the nucleus basalis of Meynert (NBM). NGF levels were m...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2008.11.004
更新日期：2009-02-01 00:00:00
abstract：:Avian cochlear neurons of the nucleus magnocellularis (NMC) are known to encode temporal information of sound. The neuron generated only a single action potential at a stable timing even though suprathreshold currents of long duration (> 100 ms) was injected. The threshold for the action potential was -42 mV. In volta...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(96)01071-1
更新日期：1996-09-01 00:00:00
abstract：:Epidermal growth factor (EGF) is a well-known neurotrophic factor regulating the development of various neuronal cells, including dopaminergic neurons, and dysfunction of EGF signals has been demonstrated as a risk factor for schizophrenia. Recently, several researchers have investigated associations including age at ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.08.004
更新日期：2006-12-01 00:00:00
abstract：:Although the rat has been the predominant rodent used to investigate the pathophysiology and treatment of experimental spinal cord injury (SCI), the increasing availability of transgenic animals has led to greater use of mouse models. However, behavioral assessment after SCI in mice has been less extensively investiga...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2010.02.009
更新日期：2010-06-01 00:00:00
abstract：:The neural pathways underlying the respiratory responses elicited by electrical or chemical stimulation of the lateral part of the periaqueductal gray (lPAG) remain unsettled. In the present study, we examined the lPAG projection to neurokinin-1 receptor (NK1R)-immunoreactive (ir) neurons in the ventrolateral medulla ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2012.08.001
更新日期：2012-10-01 00:00:00
abstract：:RNA editing provides a post-transcriptional mechanism to increase structural heterogeneity of gene products. Recently, the alpha3 subunit of the GABAA receptors has been shown to undergo RNA editing. As a result, a highly conserved isoleucine residue in the third transmembrane domain is replaced with a methionine. To ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2009.01.003
更新日期：2009-04-01 00:00:00
abstract：:Following neonatal hypoxia-ischemia (HI) serotonin (5-hydroxytryptamine, 5-HT) levels are decreased in the brain. The regulation of brain 5-HT is dependent on the serotonin transporter (SERT) localised at the neuronal pre-synaptic cell membrane. However SERT can also traffic away from the cell membrane into the cytoso...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2012.04.002
更新日期：2012-07-01 00:00:00
abstract：:Recent technologies and developments in neuroscience have contributed to remarkable scientific discoveries, and have also raised many new philosophical, ethical, legal, and social issues. Research in "neuroethics" has identified various ethical issues, which will be difficult for current biomedical ethics to resolve f...
journal_title：Neuroscience research
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.neures.2006.09.004
更新日期：2007-01-01 00:00:00
abstract：:In this communication, I first summarize the mechanisms underlying human voluntary movements and define the involuntary movements (medical term). CLASSIFICATION OF HUMAN MOVEMENTS:Human movements are classified into two main kinds: intentional movements and non-intentional movements in which the involuntary movements...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2019.10.001
更新日期：2020-07-01 00:00:00
abstract：:Whole-cell recordings were performed to examine the morphological properties of electrophysiologically classified area postrema (AP) neurons in rat brain slices. Using electrophysiological criteria, AP neurons were subdivided into three groups: (1) cells displaying both the hyperpolarization-activated cation current (...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2005.10.005
更新日期：2006-01-01 00:00:00
abstract：:In previous studies we provided evidence for changes in prolactin (PRL) receptor levels in the male rat brain after continuously infusing morphine using subcutaneously implanted miniosmotic pumps. In this work we have studied the binding of PRL in the male rat brain following morphine administration by both subcutaneo...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(95)00953-1
更新日期：1995-10-01 00:00:00
abstract：:To study the contribution of retinal and cortical afferents to the patterns of glutamate- and homocysteate-like immunoreactivities in dorsal lateral geniculate, combined retinal and cortical ablations were performed in rats. In controls, glutamate immunoreactivity was in terminal-like dots and neurons. Homocysteate im...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(97)01162-0
更新日期：1997-04-01 00:00:00
abstract：:Because a potential treatment for brain injuries could be elevating magnesium ions (Mg(2+)) intracerebrally, we characterized the effects of elevating external Mg(2+) in cultures of neonatal murine brain-derived neural stem/progenitor cells (NSCs). Using a crystal violet assay, which avoids interference of Mg(2+) in t...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2014.05.001
更新日期：2014-07-01 00:00:00
abstract：:Visual-spatial navigation in familiar and unfamiliar environments is an essential requirement of daily life. Animal studies indicated the importance of the hippocampus for navigation. Neuroimaging studies demonstrated gender difference or strategies dependent difference of neural substrates for navigation. Using funct...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.04.009
更新日期：2006-08-01 00:00:00
abstract：:A brain-machine interface (BMI) uses neurophysiological signals from the brain to control external devices, such as robot arms or computer cursors. Combining augmented reality with a BMI, we show that the user's brain signals successfully controlled an agent robot and operated devices in the robot's environment. The u...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2009.10.006
更新日期：2010-02-01 00:00:00
abstract：:Disturbed circadian rhythmicity is associated with human diseases such as sleep and mood disorders. However, study of human endogenous circadian rhythm is laborious and time-consuming, which hampers the elucidation of diseases. It has been reported that peripheral tissues exhibit circadian rhythmicity as the suprachia...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2009.10.007
更新日期：2010-02-01 00:00:00
abstract：:While the role of creatine in preventing muscle (peripheral) fatigue for high performance athletes is well understood, its biochemical role in prevention of mental (central) fatigue is not. Creatine is abundant in muscles and the brain and after phosphorylation used as an energy source for adenosine triphosphate synth...
journal_title：Neuroscience research
pub_type： 临床试验,杂志文章
doi：10.1016/s0168-0102(02)00007-x
更新日期：2002-04-01 00:00:00
abstract：:The actin cytoskeleton plays a critical role in the cellular morphological changes. Its organization is essential for neurite extension and synaptogenesis under the processes of neuronal development. Recently, neural Wiskott-Aldrich syndrome protein (N-WASP) and WASP family verprolin-homologous protein (WAVE) have bee...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.09.007
更新日期：2006-12-01 00:00:00
abstract：:In the mammalian central nervous system (CNS), transcription factor activator protein 2 (AP-2) is one of the critical regulatory factors for neural gene expression and neural development. As AP-2 has diverged into several subtypes, i.e. AP-2alpha, -2beta, and 2.2, we investigated the distribution of the AP-2 subtypes ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(99)00017-6
更新日期：1999-04-01 00:00:00
abstract：:The facilitatory masseteric muscle response (FMR) elicited by polyurethane foam strip application between the opposing molars during cortically-induced rhythmic jaw movements (CRJMs) was induced earlier than masticatory force onset. The occurrence of this early response of the FMR (e-FMR) could not be explained by a s...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(00)00192-9
更新日期：2001-01-01 00:00:00
