Basal forebrain stimulation induces NGF secretion in ipsilateral parietal cortex via nicotinic receptor activation in adult, but not aged rats.

abstract：:Tissue-type plasminogen activator (tPA) is a serine protease that converts the inactive precursor plasminogen to the active protease plasmin. In the central nervous system, tPA has been suggested to participate in plasticity, memory and the neuronal degeneration caused by excitotoxins, but its precise functions during...

journal_title：Neuroscience research

authors： Nagai N,Urano T,Endo A,Takahashi H,Takada Y,Takada A

更新日期：1999-02-01 00:00:00

abstract：:The neural pathways underlying the respiratory responses elicited by electrical or chemical stimulation of the lateral part of the periaqueductal gray (lPAG) remain unsettled. In the present study, we examined the lPAG projection to neurokinin-1 receptor (NK1R)-immunoreactive (ir) neurons in the ventrolateral medulla ...

journal_title：Neuroscience research

authors： Oka T,Yokota S,Tsumori T,Niu JG,Yasui Y

更新日期：2012-10-01 00:00:00

abstract：:The aim of this study was to investigate the differences between children and adults in recognizing facial expressions of simple line drawings of "Chernoff's face". First, the angles of the eyebrows and mouth of Chernoff's face were changed in a stepwise way with a personal computer, and the emotional response of the ...

journal_title：Neuroscience research

authors： Tsurusawa R,Goto Y,Mitsudome A,Nakashima T,Tobimatsu S

更新日期：2008-02-01 00:00:00

abstract：:Using Mayahara's method, the distribution of K(+)-dependent p-nitrophenylphosphatase activity was examined electron microscopically in the synaptic regions of the cerebral cortex of 10, 15 and 60-day-old Wistar rats. The enzyme achieved gradually its characteristic localization and uniform distribution. The main devel...

journal_title：Neuroscience research

authors： Dolapchieva S

更新日期：1996-02-01 00:00:00

abstract：:Some evidence suggests that sleep deprivation might impair synaptic plasticity and produce oxidative stress in the hippocampus. However it is not clear whether impairment of long-term potentiation depends on the oxidative stress evoked by sleep deprivation protocol. In this study we aimed to investigate the effects of...

journal_title：Neuroscience research

authors： Süer C,Dolu N,Artis AS,Sahin L,Yilmaz A,Cetin A

更新日期：2011-05-01 00:00:00

abstract：:Light-induced changes in the input resistance (Rin) of external, luminosity (i.e. H1) type horizontal cell (HC) perikarya were studied by the bridge-balance method in light-adapted and dark-adapted retinae of carp. Changes in input resistance (delta Rin) induced by short-(460 nm) and long-wavelength (674 nm) flashes, ...

journal_title：Neuroscience research

authors： Furukawa T,Yamada M,Petruv R,Djamgoz MB,Yasui S

更新日期：1997-01-01 00:00:00

abstract：:Immuno-electron microscopy specifically enhanced with silver staining has been used to demonstrate the localization of calcitonin gene-related peptide (CGRP) in the ependymocytes of the hamster subcommissural organ (SCO). Hamster SCO consists of the ependymal and hypendymal cell layers, the latter being arranged as ro...

journal_title：Neuroscience research

authors： Tsai MH,Wu CH,Chen WP,Shieh JY,Wen CY

更新日期：2003-09-01 00:00:00

abstract：:NMDA receptors play an important functional role in the neuron excitability and plasticity. The conditions and consequences of their activation are of interest for many neuroscientists. This investigation was designed to explore an activation of the NMDA receptors of frog tectal neurons in vivo by a burst of spikes of...

journal_title：Neuroscience research

authors： Kuras A,Baginskas A,Batuleviciene V

更新日期：2006-04-01 00:00:00

abstract：:Using a confocal laser scanning microscope (CLSM) and an electron microscope, we investigated the organization of the main olfactory bulb (MOB) of tenrecs, which were previously included into insectivores but now considered to be in a new order "Afrosoricida" in the superclade 'Afrotheria'. We confirmed that the overa...

journal_title：Neuroscience research

authors： Kosaka K,Künzle H,Kosaka T

更新日期：2005-12-01 00:00:00

abstract：:Many studies on long-term potentiation (LTP) in hippocampal region CA1 focus on receptor-mediated events that are often presumed to be linked to postsynaptic processes. Whereas it is now well-known that LTP consists of multiple components involving increases in postsynaptic responsiveness as well as enhanced presynapt...

journal_title：Neuroscience research

authors： Hicks TP,Ito KI

更新日期：1996-01-01 00:00:00

abstract：:Acute exposure to kainic acid (KA) induces neurochemical changes in dopaminergic systems in the brain and the aim of the present study was to investigate the acute toxicity of KA upon dopamine D2 receptors. Adult rats were injected intraperitoneally with either saline or 16 mg/kg KA. Brains were removed after 4 h. Mem...

journal_title：Neuroscience research

authors： Ridd MJ,Kitchen I,Fosbraey P

更新日期：1998-03-01 00:00:00

abstract：:Hippocalcin is a recently identified Ca(2+)-binding protein with three EF-hand structures, dominantly expressed in the hippocampal pyramidal layer. The complete amino acid sequence of hippocalcin deduced from the cDNA is composed of 195 residues, has a calculated molecular mass of 22,574 daltons, and has a striking se...

journal_title：Neuroscience research

authors： Takamatsu K,Noguchi T

更新日期：1993-09-01 00:00:00

abstract：:The Approach-Avoidance Task (AAT) measures automatic approach-avoidance tendencies and their regulation: compatible reactions (approach positive, avoid negative) are faster than incompatible ones (approach negative, avoid positive). The present study assessed event-related potentials (ERPs) in 15 healthy persons for d...

journal_title：Neuroscience research

authors： Ernst LH,Ehlis AC,Dresler T,Tupak SV,Weidner A,Fallgatter AJ

更新日期：2013-03-01 00:00:00

abstract：:Because a potential treatment for brain injuries could be elevating magnesium ions (Mg(2+)) intracerebrally, we characterized the effects of elevating external Mg(2+) in cultures of neonatal murine brain-derived neural stem/progenitor cells (NSCs). Using a crystal violet assay, which avoids interference of Mg(2+) in t...

journal_title：Neuroscience research

authors： Vennemeyer JJ,Hopkins T,Kuhlmann J,Heineman WR,Pixley SK

更新日期：2014-07-01 00:00:00

abstract：:Changes in synaptic efficacy at the parallel fiber (PF)-Purkinje cell (PC) synapse are postulated to be a cellular basis for motor learning. Although long-term efficacy changes lasting more than an hour at this synapse, i.e., long-term potentiation and depression, have been extensively studied, relatively short lastin...

journal_title：Neuroscience research

authors： Goto J,Inoue T,Kuruma A,Mikoshiba K

更新日期：2006-05-01 00:00:00

abstract：:Recent technological progress has yielded great amounts of information about the molecular constituents of postsynaptic scaffolds in the dendritic spine. Actin filaments are major cytoskeletal elements in the dendritic spine, and they functionally interact with neurotransmitter receptors via regulatory actin-binding p...

journal_title：Neuroscience research

authors： Shirao T,Sekino Y

更新日期：2001-05-01 00:00:00

abstract：:How the nervous system controls the sensation and memory of information from the environment is an essential question. The nematode Caenorhabditis elegans is a useful model for elucidating neural information processing that mediates sensation and memory. The entire nervous system of C. elegans consists of only 302 neu...

journal_title：Neuroscience research

authors： Ohta A,Kuhara A

更新日期：2013-07-01 00:00:00

abstract：:Alcoholism is a psychiatric condition that develops through neuroadaptations in response to neuronal stresses caused by chronic ethanol intake. Neurons can adapt to ethanol-induced metabolic changes by activating cellular protective mechanisms, including autophagy. Here we show that expression of Ulk1, a gene critical...

journal_title：Neuroscience research

authors： Sumitomo A,Ueta K,Mauchi S,Hirai K,Horike K,Hikida T,Sakurai T,Sawa A,Tomoda T

更新日期：2017-04-01 00:00:00

abstract：:Medial preoptic area (MPA), supraoptic nucleus (SON), magnocellular (MaPVN) and parvocellular (PaPVN) paraventricular hypothalamic nuclei, and mesencephalic lateral tegmentum (MLT) are involved in maternal behavior, parturition and lactation. This study investigated the FosB and Fos immunoreactivity in these regions o...

journal_title：Neuroscience research

authors： Lin SH,Miyata S,Weng W,Matsunaga W,Ichikawa J,Furuya K,Nakashima T,Kiyohara T

更新日期：1998-12-01 00:00:00

abstract：:Motor imagery (MI) is a mental practice that reproduces the visual- and/or kinesthetic-modality brain activations accompanying movement. It is a useful rehabilitation technique as the affected motor cortex can be stimulated in patients with stroke and hemiplegia. However, most patients with stroke have difficulty with...

journal_title：Neuroscience research

authors： Tani M,Ono Y,Matsubara M,Ohmatsu S,Yukawa Y,Kohno M,Tominaga T

更新日期：2018-08-01 00:00:00

abstract：:By combining biochemical, molecular and immunohistochemical approaches, we have investigated the presence of metabotropic glutamate receptors (mGluRs) belonging to the subtype 5 in rat and human spinal cords and the developmental changes in their expression. A polyclonal antibody raised against the carboxy-terminal po...

journal_title：Neuroscience research

authors： Valerio A,Rizzonelli P,Paterlini M,Moretto G,Knöpfel T,Kuhn R,Memo M,Spano P

更新日期：1997-05-01 00:00:00

abstract：:Forebrain heat shock protein 70 (HSP70) immunohistochemical reactivity was investigated in rats subjected to gamma knife irradiation focusing on the right caudate putamen nucleus. The forebrain sections of all experimental animals were processed with anti-HSP70 antiserum and then by avidin-biotin peroxidase complex im...

journal_title：Neuroscience research

authors： Rao ZR,Ge X,Qiou JY,Yang T,Duan L,Ju G

更新日期：2000-10-01 00:00:00

abstract：:The interaction of neurotransmitter receptors with the underlying cytoskeleton via subsynaptic proteins is an important mechanism for the targeting of the receptors to synapses in the central nervous system. We show that delta glutamate receptors (delta receptors), expressed predominantly in the dendritic spines of ce...

journal_title：Neuroscience research

authors： Hirai H,Matsuda S

更新日期：1999-09-01 00:00:00

abstract：:Using techniques of combining intracellular recording and intracellular staining with biocytin, 19 neurons have been sampled within or close to the CA1 pyramidal cell layer in hippocampal slices of the rat. All of these cells were physiologically characterized as non-pyramidal or interneurons based on their action pot...

journal_title：Neuroscience research

authors： Han ZS

更新日期：1996-05-01 00:00:00

abstract：:Event-related potentials (ERPs) during an auditory discrimination task were recorded both on the surface and at a depth of the auditory cortex in rats. Ten-kilohertz rare and 5-kHz frequent tones were used with the probabilities of 0.2 and 0.8. Lever pressing within 2 s, following the onset of the rare tone, was rewar...

journal_title：Neuroscience research

authors： Iwanami A,Shinba T,Sumi M,Ozawa N,Yamamoto K

更新日期：1994-11-01 00:00:00

abstract：:The present study was performed to determine whether the voltage gated Cl- channel (CLC) expression is altered in the hippocampus of seizure sensitive (SS) gerbils, and to identify the strong fast paired-pulse inhibition in the dentate gyrus of SS gerbils is associated with altered CLC expression. In the hippocampal p...

journal_title：Neuroscience research

authors： Kim DS,Yoo KY,Hwang IK,Jung JY,Won MH,Choi SY,Kwon OS,Seo JH,Kang TC

更新日期：2005-01-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear protein that plays an essential role in diverse neurobiological processes. However, the role of PPARα on the sleep modulation is unknown. Here, rats treated with an intrahypothalamic injection of Wy14643 (10μg/1μL; PPARα agonist) enhanced wakefu...

journal_title：Neuroscience research

authors： Mijangos-Moreno S,Poot-Aké A,Guzmán K,Arankowsky-Sandoval G,Arias-Carrión O,Zaldívar-Rae J,Sarro-Ramírez A,Murillo-Rodríguez E

更新日期：2016-04-01 00:00:00

abstract：:Excitatory inputs to layer V neurons of the parasubiculum and medial entorhinal cortex were examined in rat brain slices with intracellular and field potential recordings. Single extracellular stimuli to layer V evoked subthreshold excitatory postsynaptic potentials (EPSPs) or a long duration (>100 ms) depolarization ...

journal_title：Neuroscience research

authors： Funahashi M,Matsuo R,Stewart M

更新日期：2002-01-01 00:00:00

abstract：:The NRG1 growth factor and ERBB4 receptor have been identified as leading schizophrenia risk genes. Although NRG1 and ERBB4 have been shown to modulate neuronal functions involved in schizophrenia, including both GABAergic and glutamatergic synapses, the exact molecular mechanisms remain poorly understood. Here we inv...

journal_title：Neuroscience research

authors： Allison JG,Das PM,Ma J,Inglis FM,Jones FE

更新日期：2011-06-01 00:00:00

abstract：:We used functional magnetic resonance imaging in 18 normal volunteers to determine whether there is separate representation of syntactic, semantic, and verbal working memory processing in the left inferior frontal gyrus (GFi). We compared a sentence comprehension task with a short-term memory maintenance task to ident...

journal_title：Neuroscience research

authors： Uchiyama Y,Toyoda H,Honda M,Yoshida H,Kochiyama T,Ebe K,Sadato N

更新日期：2008-07-01 00:00:00