Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation.

abstract：:It has been indicated that Pyk2/Src signaling pathway is involved in modulation of N-methyl-D-aspartate-type (NMDA) glutamate receptor activity. Lithium protects against glutamate-induced excitotoxicity in cultured neurons and in animal models of diseases. The neuroprotection against excitotoxicity afforded by lithium...

journal_title：Neuroscience research

authors： Ma J,Zhang GY,Liu Y,Yan JZ,Hao ZB

更新日期：2004-08-01 00:00:00

abstract：:The DYT1 gene containing a trinucleotide deletion (DeltaGAG) is linked to early-onset dystonia, a neurological movement disorder of involuntary muscle contractions. To understand DYT1's contribution to dystonia, we produced and analyzed Dyt1 knockdown (KD) mice that expressed a reduced level of torsinA protein encoded...

journal_title：Neuroscience research

authors： Dang MT,Yokoi F,Pence MA,Li Y

更新日期：2006-12-01 00:00:00

abstract：:Recently, we have found novel mammalian tachykinins, neurokinin alpha and beta isolated from porcine spinal cord, whose chemical structures are similar to those of substance P or kassinin. In the present study, we describe a specific assay system for neurokinin alpha and beta by combining HPLC and radioimmunoassay. We...

journal_title：Neuroscience research

authors： Kanazawa I,Ogawa T,Kimura S,Munekata E

更新日期：1984-12-01 00:00:00

abstract：:We investigated how much time wild-type Caenorhabditis elegans (Bristol N2) nematodes and the GABA-deficient unc25 mutant and the vesicular GABA transporter-deficient unc47 mutant spent moving. The worms were allowed to move freely on the surface of agarose plates either with or without the food bacterium OP50. We ide...

journal_title：Neuroscience research

authors： Shingai R

更新日期：2000-09-01 00:00:00

abstract：:We suggest a time-varying partial correlation as a statistical measure of dynamic functional connectivity (dFC) in the human brain. Traditional statistical models often assume specific distributions on the measured data such as the Gaussian distribution, which prohibits their application to neuroimaging data analysis....

journal_title：Neuroscience research

authors： Lee N,Kim JM

更新日期：2020-07-03 00:00:00

abstract：:We investigated the distribution and colocalization pattern of the two corticosteroid receptors, mineralocorticoid receptor (MR) and glucocorticoid receptor (GR), in the hippocampus and hypothalamus, the main target regions of corticosterone in the rat brain, using double immunofluorescence histochemistry in conjuncti...

journal_title：Neuroscience research

authors： Han F,Ozawa H,Matsuda K,Nishi M,Kawata M

更新日期：2005-04-01 00:00:00

abstract：:Expressions of Cry1 and Cry2 mRNA in the rat pineal gland were examined by Northern blot. The levels of Cry1 and Cry2 transcript had a marked circadian rhythm with peaks at circadian time (CT) 20 in constant darkness. But the amplitude of the Cry1 rhythm was higher than that of the Cry2 rhythm. Furthermore, a signific...

journal_title：Neuroscience research

authors： Nakamura TJ,Shinohara K,Funabashi T,Mitsushima D,Kimura F

更新日期：2001-09-01 00:00:00

abstract：:Temporal changes in kainate-induced seizure activity and hippocampal NO generation were evaluated simultaneously in conscious rats by using in vivo microdialysis and by determining the concentrations of nitrite and nitrate in perfusates. Intraperitoneal injection of kainic acid produced 'wet dog shake', focal seizure ...

journal_title：Neuroscience research

authors： Kashihara K,Sakai K,Marui K,Shohmori T

更新日期：1998-11-01 00:00:00

abstract：:The older neurocentric view of the central nervous system (CNS) has changed radically with the growing understanding of the many essential functions of astrocytes. Advances in our understanding of astrocytes include new observations about their structure, organization, function and supportive actions to other cells. A...

journal_title：Neuroscience research

authors： Barreto GE,Gonzalez J,Torres Y,Morales L

更新日期：2011-10-01 00:00:00

abstract：:Effective connectivity analysis has been widely applied to noninvasive recordings such as functional magnetic resonance imaging and electroencephalograms (EEGs). Previous studies have aimed to extract the causal relations between brain regions, but the validity of the derived connectivity has not yet been fully determ...

journal_title：Neuroscience research

authors： Ye S,Kitajo K,Kitano K

更新日期：2020-07-01 00:00:00

abstract：:Angiotensin II (Ang II) receptors are located in different regions of the brain, particularly within the cardiovascular control centers in the brainstem. These Ang II receptors are divided into AT1 and AT2 subtypes. We investigated the role of AT1 receptor subtype within the rostral (RVLM) and caudal (CVLM) ventrolate...

journal_title：Neuroscience research

authors： Patel D,Böhlke M,Phattanarudee S,Kabadi S,Maher TJ,Ally A

更新日期：2008-03-01 00:00:00

abstract：UNLABELLED:Angiotensin II receptors (Ang II), classified into AT1 and AT2 subtypes, are located in different regions of the central nervous system, including the cardiovascular control centers in the medulla oblongata. We previously reported the role of Ang II AT1 receptors within the medulla on cardiovascular response...

journal_title：Neuroscience research

authors： Tedesco A,Ally A

更新日期：2009-08-01 00:00:00

abstract：:The effect of diazepam (DZP) on the GABA-induced macroscopic and microscopic Cl- current was investigated in isolated frog sensory neurons using both 'concentration-clamp' and patch-clamp techniques. At concentration range between 10(-9) and 10(-4) M, DZP itself evoked no response but potentiated time- and dose-depend...

journal_title：Neuroscience research

authors： Yakushiji T,Tokutomi N,Akaike N

更新日期：1989-04-01 00:00:00

abstract：:By combining biochemical, molecular and immunohistochemical approaches, we have investigated the presence of metabotropic glutamate receptors (mGluRs) belonging to the subtype 5 in rat and human spinal cords and the developmental changes in their expression. A polyclonal antibody raised against the carboxy-terminal po...

journal_title：Neuroscience research

authors： Valerio A,Rizzonelli P,Paterlini M,Moretto G,Knöpfel T,Kuhn R,Memo M,Spano P

更新日期：1997-05-01 00:00:00

abstract：:Sleep disturbances are common in psychiatric disorders, but the causal relationship between the two and the underlying genetic factors is unclear. The DISC1 gene is strongly linked to mood disorders and schizophrenia in a Scottish pedigree. In an earlier study we found a sleep homeostasis disturbance in a Drosophila m...

journal_title：Neuroscience research

authors： Jaaro-Peled H,Altimus C,LeGates T,Cash-Padgett T,Zoubovsky S,Hikida T,Ishizuka K,Hattar S,Mongrain V,Sawa A

更新日期：2016-11-01 00:00:00

abstract：:Effect of serotonin on nitric oxide (NO) production in the ventral nerve cord (VNC) of the earthworm Eisenia fetida was investigated by a bio-imaging and an electrochemical technique. In the bio-imaging, the spatial pattern of NO production in VNC was visualized using an NO-specific fluorescent dye, diaminofluorescein...

journal_title：Neuroscience research

authors： Kitamura Y,Naganoma Y,Horita H,Ogawa H,Oka K

更新日期：2001-10-01 00:00:00

abstract：:We have been advocating cognitive developmental robotics to obtain new insight into the development of human cognitive functions by utilizing synthetic and constructive approaches. Among the different emotional functions, empathy is difficult to model, but essential for robots to be social agents in our society. In my...

journal_title：Neuroscience research

authors： Asada M

更新日期：2015-01-01 00:00:00

abstract：:Changes in the features of responses of cortical taste neurons were studied in granular insular (GI) and dysgranular insular (DI) areas of urethane-anesthetized SD rats of four age groups (4-10, 14-20, 25-35 and > 90 days). Stimuli included four basic taste stimuli, 0.1 M NH4Cl, and the water extract of a food pellet,...

journal_title：Neuroscience research

authors： Ogawa H,Hasegawa K,Ohgushi M,Murayama N

更新日期：1994-06-01 00:00:00

abstract：:Hippocalcin is a recently identified Ca(2+)-binding protein with three EF-hand structures, dominantly expressed in the hippocampal pyramidal layer. The complete amino acid sequence of hippocalcin deduced from the cDNA is composed of 195 residues, has a calculated molecular mass of 22,574 daltons, and has a striking se...

journal_title：Neuroscience research

authors： Takamatsu K,Noguchi T

更新日期：1993-09-01 00:00:00

abstract：:The effects of acupuncture-like stimulation of the various segmental areas on gastric motility were examined in anesthetized rats. An acupuncture needle (diameter 340 microns) was inserted into the skin and underlying muscles at a depth of 4-5 mm and was twisted right and left once every second for 60 s. Gastric motil...

journal_title：Neuroscience research

authors： Sato A,Sato Y,Suzuki A,Uchida S

更新日期：1993-10-01 00:00:00

abstract：:The entopeduncular nucleus (EPN) is one of the major output nuclei of the basal ganglia in rodents. Previous studies have divided it into rostral and caudal halves, with the former containing somatostatin (SOM)-immunoreactive neurons and the latter dominated by parvalbumin (PV)-containing neurons, respectively. Howeve...

journal_title：Neuroscience research

authors： Miyamoto Y,Fukuda T

更新日期：2015-05-01 00:00:00

abstract：:Different tracer substances were injected into the superior colliculus (CoS) in order to study its afferents and efferents with the meso-rhombencephalic tegmentum, the precerebellar nuclei and the cerebellum in the Madagascan hedgehog tenrec. The overall pattern of tectal connectivity in tenrec was similar to that in ...

journal_title：Neuroscience research

authors： Künzle H

更新日期：1997-06-01 00:00:00

abstract：:[3H]Glutamic acid binding to hippocampi was increased after amygdaloid kindling in rats, and diazepam inhibited this increased binding, without any effect on the enhanced binding by CaCl2 or the binding in control rats. By inducing kindling in the same way as that used in the binding experiment, the inhibiting effects...

journal_title：Neuroscience research

authors： Oka J,Yamada M,Goto M,Fukuda H

更新日期：1987-02-01 00:00:00

abstract：:Excitatory inputs to layer V neurons of the parasubiculum and medial entorhinal cortex were examined in rat brain slices with intracellular and field potential recordings. Single extracellular stimuli to layer V evoked subthreshold excitatory postsynaptic potentials (EPSPs) or a long duration (>100 ms) depolarization ...

journal_title：Neuroscience research

authors： Funahashi M,Matsuo R,Stewart M

更新日期：2002-01-01 00:00:00

abstract：:Using a mouse Thy-1 allelic system (an AKR strain of Thy-1.1 was used as the host and a BALB/c strain of Thy-1.2 as the graft), characteristics of transplant-to-host axon projection and synapse formation of the olfactory bulb (OB) were studied in the hippocampal formation by immunohistochemical and ultrastructural exa...

journal_title：Neuroscience research

authors： Fujii M,Hayakashi T

更新日期：1995-12-01 00:00:00

abstract：:GABAergic neurons in the hippocampus proper are greatly diverse in their morphological and physiological features. In the present study we examined whether or not they are also diverse regarding the density of GABAergic input on their somata. GABAergic neurons were immunocytochemically identified with antibodies again...

journal_title：Neuroscience research

authors： Fukuda T,Aika Y,Heizmann CW,Kosaka T

更新日期：1996-10-01 00:00:00

abstract：:In this conceptual review, we highlight our strategy for, and progress in the development of corticospinal neuroprostheses for restoring locomotor functions and promoting neural repair after thoracic spinal cord injury in experimental animal models. We specifically focus on recent developments in recording and stimula...

journal_title：Neuroscience research

authors： Borton D,Bonizzato M,Beauparlant J,DiGiovanna J,Moraud EM,Wenger N,Musienko P,Minev IR,Lacour SP,Millán Jdel R,Micera S,Courtine G

更新日期：2014-01-01 00:00:00

abstract：:Action potentials, when arriving at presynaptic terminals, elicit Ca(2+) influx through voltage-gated Ca(2+) channels. Intracellular [Ca(2+)] elevation around the channels subsequently triggers synaptic vesicle exocytosis and also induces various protein reactions that regulate vesicle endocytosis and recycling to pro...

journal_title：Neuroscience research

authors： Yamashita T

更新日期：2012-05-01 00:00:00

abstract：:Neuronal circuits are intensively shaped depending on experiences received during developmental critical periods. How neuronal circuits are sculpted can even affect the later development of higher cognitive functions, such as vocal communication skills. Here, we propose songbirds that learn to sing from early auditory...

journal_title：Neuroscience research

authors： Yazaki-Sugiyama Y

更新日期：2019-03-01 00:00:00

abstract：:The purposes of the present study were to determine which upper airway movements cause a difference in the expiratory airflow pathway between sneezing and coughing, and to develop a new animal model for studying the neural mechanism of sneezing in paralyzed animals, i.e. fictive sneezing. We compared the upper airway ...

journal_title：Neuroscience research

authors： Satoh I,Shiba K,Kobayashi N,Nakajima Y,Konno A

更新日期：1998-10-01 00:00:00