Abstract：
:[3H]Glutamic acid binding to hippocampi was increased after amygdaloid kindling in rats, and diazepam inhibited this increased binding, without any effect on the enhanced binding by CaCl2 or the binding in control rats. By inducing kindling in the same way as that used in the binding experiment, the inhibiting effects of diazepam on kindled seizures, the afterdischarge and the development of kindling were observed.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Oka J,Yamada M,Goto M,Fukuda Hdoi
10.1016/0168-0102(87)90011-3subject
Has Abstractpub_date
1987-02-01 00:00:00pages
185-94issue
3eissn
0168-0102issn
1872-8111pii
0168-0102(87)90011-3journal_volume
4pub_type
杂志文章abstract：:This paper describes for the first time the phenomenon of spatio-temporal mapping of interchannel temporal coincidences of rapid transition processes (RTPs) in multiple EEG frequencies. It is suggested that RTPs in multiple EEG frequencies found in different EEG channels could reflect the process of switching between ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2010.07.2031
更新日期：2010-11-01 00:00:00
abstract：:Amyloid-beta (Aβ) peptides, Aβ 1-42 (Aβ42) and Aβ43 in particular, cause neurotoxicity and cell death in the brain of Alzheimer's disease (AD) at higher concentrations. Carnosic acid (CA), a phenolic diterpene compound in the labiate herbs rosemary and sage, serves as an activator for neuroprotective and neurotrophic ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2014.12.003
更新日期：2015-05-01 00:00:00
abstract：:The effects of 5-HT3-receptor-related agents on long-term potentiation (LTP) in the mossy fiber-CA3 system were studied in guinea pig hippocampal slices. 5-HT3 receptor agonists, 1-(m-chlorophenyl)-biguanide (mCPBG) and 2-methyl serotonin (2-Me-5-HT) significantly attenuated the magnitude of LTP of the population spik...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(94)90163-5
更新日期：1994-01-01 00:00:00
abstract：:Slow disjunctive eye movement similar to ocular convergence was evoked by microstimulation in parts of the lateral suprasylvian area (LSA) in alert cats. A tungsten-in-glass microelectrode was used for stimulation, and eye movement was monitored using the magnetic search coil method. The velocity-versus-amplitude rela...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(91)90120-n
更新日期：1991-10-01 00:00:00
abstract：:The hypothalamic paraventricular nuclei (PVN) inhibits spinal nociception. Furthermore, projections from the PVN to other structures related to pain modulation exist, but a functional interaction has not yet been fully demonstrated. As an initial approach, we show here that PVN electric stimulation with the same param...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2015.04.004
更新日期：2015-09-01 00:00:00
abstract：:Metabolism of amyloid-beta peptide (Abeta) is closely associated with the pathology and etiology of Alzheimer's disease (AD). Since neprilysin is the only rate-limiting catabolic peptidase proven by reverse genetics to participate in Abeta metabolism in vivo, we performed detailed immunohistochemical analysis of nepri...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(02)00015-9
更新日期：2002-05-01 00:00:00
abstract：:Sensitivities of neurons to acetylcholine (ACh), noradrenaline (NA) and dopamine (DA) were investigated at different depths of the dorsolateral prefrontal cortex (PFC) in awake or halothane-anesthetized macaque monkeys, using microiontophoretic techniques with multi-barreled electrodes. The laminar locations of tested...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(85)90004-5
更新日期：1985-04-01 00:00:00
abstract：:Chemokines are a family of peptides originally identified as the factors regulating the migration of leukocytes in inflammatory and immune responses. Recently, they have been shown to be produced in the central and peripheral nervous systems under various pathological conditions and act on neuronal and glial cells. In...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2004.01.004
更新日期：2004-04-01 00:00:00
abstract：:The distribution of neurofilament proteins and peripherin in the pituitary gland of the rat was studied with a panel of monoclonal and polyclonal antibodies recognizing different neurofilament subunits. In the posterior lobe, a dense plexus of neurofilament- and peripherin-immunoreactive fibers was seen. In the interm...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(95)00903-7
更新日期：1995-06-01 00:00:00
abstract：:Neuronal circuits are intensively shaped depending on experiences received during developmental critical periods. How neuronal circuits are sculpted can even affect the later development of higher cognitive functions, such as vocal communication skills. Here, we propose songbirds that learn to sing from early auditory...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2018.11.002
更新日期：2019-03-01 00:00:00
abstract：:Properties of the Ca2+ -activated K+ current (I[K(Ca)]) were investigated in bipolar cells isolated from the goldfish retina. Pharmacological experiments and single channel current recordings demonstrated that I[K(Ca)] represented currents through BK channels, which were confined mostly to the presynaptic terminal. Th...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(97)01155-3
更新日期：1997-03-01 00:00:00
abstract：:Many different kinds of voltage-gated ion channels (Na+ channels, K+ channels, Ca2+ channels) exist at neuronal dendrites. Integration of dendritic electric signals (excitatory postsynaptic potentials (EPSPs), inhibitory postsynaptic potentials (IPSPs) and action potentials) and/or non-electric signals (Ca2+ and secon...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/s0168-0102(00)00120-6
更新日期：2000-07-01 00:00:00
abstract：:The effect of apamin, a bee venom toxin, on the action potential and the spike after hyperpolarization was studied in bullfrog sympathetic ganglion cells. Apamin reduced the duration of the afterhyperpolarization but did not affect the maximum rates of rise and fall of Na+- and Ca2+-dependent action potentials. In the...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(85)90029-x
更新日期：1985-12-01 00:00:00
abstract：:We previously reported that the gamma gamma-isozyme of enolase, NSE), one of the glycolytic enzymes, promoted the survival of embryonic rat neocortical neurons in culture, but alpha alpha-isozyme (non-neuronal enolase) had no effect. In the present study, the neurotrophic effects of NSE on cultured mesencephalic and s...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(94)00849-b
更新日期：1995-01-01 00:00:00
abstract：:The present study investigated the effect of nicotine exposure on gustatory plasticity in the nematode Caenorhabditis elegans. The chemotactic response of wild-type N2 nematodes pre-exposed to 100mM NaCl with 3.0mM nicotine was almost the same as that of mock-conditioned nematodes unexposed to NaCl; however, the respo...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2013.09.001
更新日期：2013-11-01 00:00:00
abstract：:The effects of acupuncture-like stimulation of the various segmental areas on gastric motility were examined in anesthetized rats. An acupuncture needle (diameter 340 microns) was inserted into the skin and underlying muscles at a depth of 4-5 mm and was twisted right and left once every second for 60 s. Gastric motil...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(93)90105-y
更新日期：1993-10-01 00:00:00
abstract：:Saccadic eye movement is a rapid shift of eye position to capture an object in the environment. In this study, we will describe the fundamental properties of spontaneously evoked saccade-like rapid eye movement (SLREM) in mice in order to establish the mouse experimental model for studying saccades. Spontaneous SLREM ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2007.04.003
更新日期：2007-07-01 00:00:00
abstract：:DJ-1 is a multifunctional protein linked to recessively inherited Parkinson's disease (PD) due to loss of function mutations. Among its activities is anti-oxidant property leading to cytoprotection under oxidative stress conditions. A key effector of oxidant-induced cell death is the MAP3 kinase apoptosis signal-regul...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2010.04.002
更新日期：2010-07-01 00:00:00
abstract：:Withdrawal may be a natural model to study craving and compulsive drug seeking, since craving can be viewed as a conditioned dysphoric state. It has been suggested that functional connectivity between brain areas may be of major value in explaining excessive craving and compulsive drug seeking by providing essential l...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2007.01.011
更新日期：2007-05-01 00:00:00
abstract：:In the rat striatum numerous secretagogin (SCGN) positive neurons were scattered. They were heterogeneous in their morphological and chemical properties. We examined the colocalization of SCGN with known four interneuron markers, parvalbumin (PV), calretinin (CR), nitric oxide synthase (NOS) and choline acetyl transfe...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2017.01.004
更新日期：2017-06-01 00:00:00
abstract：:To gain insight into the basic neurobiological processes regulated by lithium--an effective drug for bipolar disorder--we used Affymetrix Genome Arrays to examine lithium-induced changes in genome-wide gene expression profiles of head mRNA from the genetic model organism Drosophila melanogaster. First, to identify the...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2009.04.015
更新日期：2009-08-01 00:00:00
abstract：:Diazepam binding inhibitor (DBI), a putative endogenous polypeptide ligand for benzodiazepine (BZD) receptors, has been shown to act as an inverse BZD receptor agonist in the brain. We previously suggested that the social isolation stress-induced decrease in pentobarbital sleeping time in mice was partly due to an inc...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(99)00010-3
更新日期：1999-03-01 00:00:00
abstract：:Tissue-type plasminogen activator (tPA) is a serine protease that converts the inactive precursor plasminogen to the active protease plasmin. In the central nervous system, tPA has been suggested to participate in plasticity, memory and the neuronal degeneration caused by excitotoxins, but its precise functions during...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(98)00125-4
更新日期：1999-02-01 00:00:00
abstract：:Effective connectivity analysis has been widely applied to noninvasive recordings such as functional magnetic resonance imaging and electroencephalograms (EEGs). Previous studies have aimed to extract the causal relations between brain regions, but the validity of the derived connectivity has not yet been fully determ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2019.09.003
更新日期：2020-07-01 00:00:00
abstract：:Using Mayahara's method, the distribution of K(+)-dependent p-nitrophenylphosphatase activity was examined electron microscopically in the synaptic regions of the cerebral cortex of 10, 15 and 60-day-old Wistar rats. The enzyme achieved gradually its characteristic localization and uniform distribution. The main devel...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(95)01004-1
更新日期：1996-02-01 00:00:00
abstract：:While the role of creatine in preventing muscle (peripheral) fatigue for high performance athletes is well understood, its biochemical role in prevention of mental (central) fatigue is not. Creatine is abundant in muscles and the brain and after phosphorylation used as an energy source for adenosine triphosphate synth...
journal_title：Neuroscience research
pub_type： 临床试验,杂志文章
doi：10.1016/s0168-0102(02)00007-x
更新日期：2002-04-01 00:00:00
abstract：:Efferent neurons to the cochlea in the guinea pig were observed in the superior olivary complex and ventral lateral lemniscal nuclei after injection of WGA-HRP into the cochlea via the round window. Of HRP-labeled nerve cells found in the brainstem, about 60% and 10% were located in the ipsilateral lateral superior ol...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(88)90003-x
更新日期：1988-10-01 00:00:00
abstract：:In the past few years, the plasticity of the regional specification of the CNS has been widely debated on the results from in utero transplantation. Two different results are reported with this transplantation method. One is that the distribution of transplanted cells is dependent on the donor origin, and the other is...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2007.06.1467
更新日期：2007-10-01 00:00:00
abstract：:We simulated brain lesions in mean diffusivity (MD) and fractional anisotropy (FA) images of healthy subjects to evaluate the performance of voxel-based analysis (VBA) with SPM2. We increased MD and decreased FA, simulating the most typical abnormalities in brain pathologies, in the superior longitudinal fasciculus (S...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2011.09.006
更新日期：2011-12-01 00:00:00
abstract：:Recently, we reported a profound depletion of cardiac sympathetic nerve fibers in Parkinson's disease (PD). This cardiac sympathetic denervation is a characteristic hallmark of PD. Cardiac sympathetic dysfunction was also observed in 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP)-treated mice, a model of PD. Al...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2007.11.011
更新日期：2008-03-01 00:00:00
