Neurotrophic and neuroprotective effects of neuron-specific enolase on cultured neurons from embryonic rat brain.

abstract：:In the present study we measured cardiovascular and respiratory reflexes evoked by administration of bradykinin and capsaicin into the hindlimb vasculature of anaesthetised rats, whilst simultaneously recording activity of sensory afferents on the adventitial surface of femoral arteries and veins. Bradykinin (0.9 nmol...

journal_title：Neuroscience research

authors： Smith PJ,McQueen DS

更新日期：2004-11-01 00:00:00

abstract：:Recently the authors showed that a computational model of visual saliency could account for changes in gaze behavior of monkeys with damage in the primary visual cortex. Here we propose a neural prosthesis to restore eye gaze behavior by electrically stimulating the superior colliculus to drive visual attention. The s...

journal_title：Neuroscience research

authors： Yoshida M,Veale R

更新日期：2014-01-01 00:00:00

abstract：:Although sleep is strongly implicated in memory consolidation, the molecular basis for the role of sleep in memory is not known. It has been established that the consolidation of hippocampus-dependent memory depends on the activation of the Erk1,2 MAP kinase (MAPK) pathway which activates de novo CRE-mediated transcri...

journal_title：Neuroscience research

authors： Xia Z,Storm D

更新日期：2017-05-01 00:00:00

abstract：:Sizes of neuronal somata in the cat cervical dorsal root ganglia were determined at different levels (C1-C8). The average value and class distribution of mean cell diameter were analyzed. The ganglia from C1 to C5 could be clearly distinguished from those at levels of brachial plexus afferents (C6-C8) with respect to ...

journal_title：Neuroscience research

authors： Rose D,Larnicol N,Duron B

更新日期：1990-02-01 00:00:00

abstract：:Considerable evidence suggests that an N-methyl-D-aspartate (NMDA) receptor plays a crucial role in memory and cognitive function. To identify the role of this receptor in higher functions of the brain, we delivered antisense oligonucleotides against an NMDA-NR1 subunit (NR1) to the hippocampus in rats using the HVJ-l...

journal_title：Neuroscience research

authors： Inada K,Ishigooka J,Anzai T,Suzuki E,Miyaoka H,Saji M

更新日期：2003-04-01 00:00:00

abstract：:By combining biochemical, molecular and immunohistochemical approaches, we have investigated the presence of metabotropic glutamate receptors (mGluRs) belonging to the subtype 5 in rat and human spinal cords and the developmental changes in their expression. A polyclonal antibody raised against the carboxy-terminal po...

journal_title：Neuroscience research

authors： Valerio A,Rizzonelli P,Paterlini M,Moretto G,Knöpfel T,Kuhn R,Memo M,Spano P

更新日期：1997-05-01 00:00:00

abstract：:The 14-3-3 protein family consists of evolutionarily conserved, acidic 30 kDa proteins composed of seven isoforms named beta, gamma, epsilon, zeta, eta, theta, and sigma in mammalian cells. The dimeric complex of 14-3-3 isoforms, acting as a molecular adaptor, plays a central role in regulation of neuronal function. S...

journal_title：Neuroscience research

authors： Tabunoki H,Shimada T,Banno Y,Sato R,Kajiwara H,Mita K,Satoh J

更新日期：2008-07-01 00:00:00

abstract：:Many forms of psychopathology and/or psychiatric illness can occur through the pathways of altered environmental sensitivity, impulsivity, social functioning, and anxious responding. While these traits are also heritable, environmental conditions are known to play a critical role. The genetic factors that contribute t...

journal_title：Neuroscience research

authors： Driscoll CA,Barr CS

更新日期：2016-01-01 00:00:00

abstract：:Damage to the central nervous system (CNS) leads to the disruption of the axonal network and causes neurological dysfunction. Recovery of neurological functions requires restoration of the axonal network; however, injured axons in the adult mammalian CNS rarely regenerate after injury. Failure of the injured axon to r...

journal_title：Neuroscience research

authors： Muramatsu R,Yamashita T

更新日期：2014-01-01 00:00:00

abstract：:Using high resolution spectral methods to uncover neuromarkers of social, cognitive and behavioral function, we have found that hemi-lateralized pairs of oscillations such as left and right occipital alpha or left and right rolandic mu dissociate spectrally. That is, they show a shifted frequency distribution, with on...

journal_title：Neuroscience research

authors： Tognoli E,Kelso JAS

更新日期：2020-07-01 00:00:00

abstract：:We investigated the distribution and colocalization pattern of the two corticosteroid receptors, mineralocorticoid receptor (MR) and glucocorticoid receptor (GR), in the hippocampus and hypothalamus, the main target regions of corticosterone in the rat brain, using double immunofluorescence histochemistry in conjuncti...

journal_title：Neuroscience research

authors： Han F,Ozawa H,Matsuda K,Nishi M,Kawata M

更新日期：2005-04-01 00:00:00

abstract：:Tissue-type plasminogen activator (tPA) is a serine protease that converts the inactive precursor plasminogen to the active protease plasmin. In the central nervous system, tPA has been suggested to participate in plasticity, memory and the neuronal degeneration caused by excitotoxins, but its precise functions during...

journal_title：Neuroscience research

authors： Nagai N,Urano T,Endo A,Takahashi H,Takada Y,Takada A

更新日期：1999-02-01 00:00:00

abstract：:Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic injury. In the present study, we examined the possibility that the n...

journal_title：Neuroscience research

authors： Candelario-Jalil E,Alvarez D,Merino N,León OS

更新日期：2003-10-01 00:00:00

abstract：:Since the first analysis of the Drosophila courtship song more than 50 years ago, the molecular and neural mechanisms underlying the acoustic communication between fruit flies has been studied extensively. The results of recent studies utilizing a wide array of genetic tools provide novel insights into the anatomic an...

journal_title：Neuroscience research

authors： Kamikouchi A

更新日期：2013-07-01 00:00:00

abstract：:It has previously been shown that when a target is moved, cats can change the direction of ongoing target-reaching with brief latency suggesting a tectal relay. Switching of target-reaching has now been investigated after spinal lesions: (1) dorsally in C5 interrupting cortico- (CS) and rubrospinal (RS) fibres to fore...

journal_title：Neuroscience research

authors： Alstermark B,Górska T,Lundberg A,Pettersson LG,Walkowska M

更新日期：1987-10-01 00:00:00

abstract：:The magnitude of long-term potentiation (LTP) was re-examined for monosynaptic transmission between mossy fibers and CA3 neurons in thin sections of the hippocampus of the guinea pig. Although an initial negative deflection in the field potential showed apparent short-term potentiation, this deflection was concluded t...

journal_title：Neuroscience research

authors： Higashima M,Yamamoto C

更新日期：1986-09-01 00:00:00

abstract：:Chemokines related neuroinflammation and N-methyl-d-aspartate receptor (NMDAR) mediated nociceptive transmission are pivotal determinants in the pathogenesis of opioid-induced hyperalgesia (OIH), but little is known about specific mechanism and treatment. Chemokine CXCL12 with its receptor CXCR4 is implicated in diffe...

journal_title：Neuroscience research

authors： Li T,Wang H,Wang J,Chen Y,Yang C,Zhao M,Wang G,Yang Z

更新日期：2019-07-01 00:00:00

abstract：:Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are inflammatory diseases of the central nervous system (CNS) characterized by localized areas of demyelination. MS is believed to be an autoimmune disorder mediated by activated immune cells such as T- and B-lymphocytes and...

journal_title：Neuroscience research

authors： Hisahara S,Okano H,Miura M

更新日期：2003-08-01 00:00:00

abstract：:Although the rat has been the predominant rodent used to investigate the pathophysiology and treatment of experimental spinal cord injury (SCI), the increasing availability of transgenic animals has led to greater use of mouse models. However, behavioral assessment after SCI in mice has been less extensively investiga...

journal_title：Neuroscience research

authors： Pajoohesh-Ganji A,Byrnes KR,Fatemi G,Faden AI

更新日期：2010-06-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) is a recently identified member of the secretin/vasoactive intestinal polypeptide (VIP) family. There are at least two types of receptor for PACAP: type I (PACAPR), which specifically binds PACAP; and type II (VIP/PACAPR), which binds both PACAP and VIP. The l...

journal_title：Neuroscience research

authors： Shioda S,Shuto Y,Somogyvari-Vigh A,Legradi G,Onda H,Coy DH,Nakajo S,Arimura A

更新日期：1997-08-01 00:00:00

abstract：:The human cerebral neocortex is divided into six layers consisting of specific neuronal cell types and connections. To determine the distribution of cortical neurons during early development, we examined the expressions of layer-specific markers in human midterm fetal brains. Layer V marker ZNF312 is expressed in most...

journal_title：Neuroscience research

authors： Zhu H,Yang Y,Gao J,Tao H,Qu C,Qu J,Chen J

更新日期：2010-09-01 00:00:00

abstract：:Saccadic eye movement is a rapid shift of eye position to capture an object in the environment. In this study, we will describe the fundamental properties of spontaneously evoked saccade-like rapid eye movement (SLREM) in mice in order to establish the mouse experimental model for studying saccades. Spontaneous SLREM ...

journal_title：Neuroscience research

authors： Sakatani T,Isa T

更新日期：2007-07-01 00:00:00

abstract：:To elucidate the interaction between nitric oxide (NO) and substance P (SP) in neurogenic inflammatory responses, we measured the change in the degree of Evans blue leakage and NO levels in perfusate from the subcutaneous space in the rat instep following noxious heat stimulation (47 degrees C for 30 min). Furthermore...

journal_title：Neuroscience research

authors： Yonehara N,Yoshimura M

更新日期：2000-01-01 00:00:00

abstract：:Functional near-infrared spectroscopy (fNIRS) is a method of monitoring brain oxygenation. This technique investigates hemodynamic changes in the cerebral cortex. fNIRS is widely used in clinical and scientific research. In this review, we focus on the applications of fNIRS on neonates. Here, applications form two dis...

journal_title：Neuroscience research

authors： Peng C,Hou X

更新日期：2020-12-30 00:00:00

abstract：:Whole-cell recordings were performed to examine the morphological properties of electrophysiologically classified area postrema (AP) neurons in rat brain slices. Using electrophysiological criteria, AP neurons were subdivided into three groups: (1) cells displaying both the hyperpolarization-activated cation current (...

journal_title：Neuroscience research

authors： Funahashi M,Mitoh Y,Akaike T,Matsuo R

更新日期：2006-01-01 00:00:00

abstract：:Striatonigral axons co-release GABA and substance P (SP) at their target sites, but little is known about the action of SP at nigral level. Therefore, we studied immunohistochemically the cellular and subcellular localization of SP and its high affinity receptors neurokinin-1 (NK-1R) and neurokinin-3 (NK-3R) at nigral...

journal_title：Neuroscience research

authors： Lévesque M,Wallman MJ,Parent R,Sík A,Parent A

更新日期：2007-03-01 00:00:00

abstract：:Changes in levels of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and neurotrophin-3 (NT-3) in various regions of the rat brain following kainic acid-induced seizure activity were investigated. BDNF protein, as measured by a two-site enzyme immunoassay, increased transiently 12-24 h after the in...

journal_title：Neuroscience research

authors： Katoh-Semba R,Takeuchi IK,Inaguma Y,Ito H,Kato K

更新日期：1999-10-01 00:00:00

abstract：:The cat perigeniculate nucleus (PGN) is a visual sector of the thalamic reticular nucleus that consists of GABAergic neurons. It receives excitatory axon-collateral input from relay neurons of the dorsal lateral geniculate nucleus (LGN) to which it provides inhibitory input. Thus, it is usually argued that the PGN wor...

journal_title：Neuroscience research

authors： Osaki H,Naito T,Soma S,Sato H

更新日期：2018-07-01 00:00:00

abstract：:Transforming growth factor beta (TGF-beta) is an extracellular signaling molecule known to mediate programmed cell death (PCD) in the developing retina. In the present study, we investigated the expression profiles and activity levels of TGF-beta ligand and TGF-beta receptors (TbetaR) during the successive physiologic...

journal_title：Neuroscience research

authors： Beier M,Franke A,Paunel-Görgülü AN,Scheerer N,Dünker N

更新日期：2006-10-01 00:00:00

abstract：:Dynamic properties of horizontal vestibulo-ocular reflex (VOR) and optokinetic response (OKR) were studied in mice. The VOR was examined in the dark (VORD), in the light (VORL) and in the condition in which most of the visual field moves synchronously with the head motion (VORF). A mouse and/or a surrounding screen wi...

journal_title：Neuroscience research

authors： Iwashita M,Kanai R,Funabiki K,Matsuda K,Hirano T

更新日期：2001-03-01 00:00:00