Abstract:
:The effect of apamin, a bee venom toxin, on the action potential and the spike after hyperpolarization was studied in bullfrog sympathetic ganglion cells. Apamin reduced the duration of the afterhyperpolarization but did not affect the maximum rates of rise and fall of Na+- and Ca2+-dependent action potentials. In the presence of apamin and Co2+, the maximum rate of fall of the action potential was decreased, and the spike duration was prolonged. These results suggest that at least two types of Ca2+-dependent K+-conductance co-exist in bullfrog sympathetic ganglion cells.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Koyano K,Abe Tdoi
10.1016/0168-0102(85)90029-xsubject
Has Abstractpub_date
1985-12-01 00:00:00pages
162-6issue
2eissn
0168-0102issn
1872-8111pii
0168-0102(85)90029-Xjournal_volume
3pub_type
杂志文章abstract::To elucidate the molecular mechanisms that regulate the maturation of action potential, we began by examining voltage-dependent K+ currents, known to contribute to the maturation of action potential, of developing granule cells in mouse cerebellar microexplant cultures. The migration of developing granule cells in thi...
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