Neuronal protein GAP-43 is a member of novel group of brain acid-soluble proteins (BASPs).

abstract：:The interaction of neurotransmitter receptors with the underlying cytoskeleton via subsynaptic proteins is an important mechanism for the targeting of the receptors to synapses in the central nervous system. We show that delta glutamate receptors (delta receptors), expressed predominantly in the dendritic spines of ce...

journal_title：Neuroscience research

authors： Hirai H,Matsuda S

更新日期：1999-09-01 00:00:00

abstract：:Different tracer substances were injected into the superior colliculus (CoS) in order to study its afferents and efferents with the meso-rhombencephalic tegmentum, the precerebellar nuclei and the cerebellum in the Madagascan hedgehog tenrec. The overall pattern of tectal connectivity in tenrec was similar to that in ...

journal_title：Neuroscience research

authors： Künzle H

更新日期：1997-06-01 00:00:00

abstract：:Immunohistochemical staining for GD3 in adult rat brain was carried out using mouse IgM anti-GD3 monoclonal antibody (DSG-1). Neuronal cells in the cerebral cortex, striatum, hippocampus and various nuclei of the thalamus were immunoreactive. In the cerebellum, Purkinje cells, granule cells and also basket cells were ...

journal_title：Neuroscience research

authors： Kawai K,Mori M,Watarai S,Yasuda T

更新日期：1994-03-01 00:00:00

abstract：:Almost all organisms on Earth have an internal biological clock, known as the circadian clock. This clock system drives robust oscillations in metabolism, physiology, and behavior, such as hormone secretions, blood pressure, and sleep/wake cycles, with a period of approximately 24h. In mammals, circadian rhythms are g...

journal_title：Neuroscience research

authors： Yamaguchi Y

更新日期：2018-04-01 00:00:00

abstract：:Because a potential treatment for brain injuries could be elevating magnesium ions (Mg(2+)) intracerebrally, we characterized the effects of elevating external Mg(2+) in cultures of neonatal murine brain-derived neural stem/progenitor cells (NSCs). Using a crystal violet assay, which avoids interference of Mg(2+) in t...

journal_title：Neuroscience research

authors： Vennemeyer JJ,Hopkins T,Kuhlmann J,Heineman WR,Pixley SK

更新日期：2014-07-01 00:00:00

abstract：:The cat perigeniculate nucleus (PGN) is a visual sector of the thalamic reticular nucleus that consists of GABAergic neurons. It receives excitatory axon-collateral input from relay neurons of the dorsal lateral geniculate nucleus (LGN) to which it provides inhibitory input. Thus, it is usually argued that the PGN wor...

journal_title：Neuroscience research

authors： Osaki H,Naito T,Soma S,Sato H

更新日期：2018-07-01 00:00:00

abstract：:The N-methyl-D-aspartate (NMDA) receptor 2B gene (GRIN2B) was studied as a candidate gene of alcoholism. This study aimed to investigate the association between each of the three GRIN2B polymorphisms (rs1806201, rs1805247, and rs1805502) and alcoholism. This study included 206 alcoholic patients and 189 unrelated cont...

journal_title：Neuroscience research

authors： Kim JH,Park M,Yang SY,Jeong BS,Yoo HJ,Kim JW,Chung JH,Kim SA

更新日期：2006-10-01 00:00:00

abstract：:NAP-22, a neuronal tissue-enriched acidic membrane protein, is a Ca(2+)-dependent calmodulin binding protein and has similar biochemical characteristics to GAP-43 (neuromodulin). Recent biochemical studies have demonstrated that NAP-22 localizes in the membrane raft domain with a cholesterol-dependent manner. Since th...

journal_title：Neuroscience research

authors： Kashihara M,Miyata S,Kumanogoh H,Funatsu N,Matsunaga W,Kiyohara T,Sokawa Y,Maekawa S

更新日期：2000-08-01 00:00:00

abstract：:While the role of creatine in preventing muscle (peripheral) fatigue for high performance athletes is well understood, its biochemical role in prevention of mental (central) fatigue is not. Creatine is abundant in muscles and the brain and after phosphorylation used as an energy source for adenosine triphosphate synth...

journal_title：Neuroscience research

authors： Watanabe A,Kato N,Kato T

更新日期：2002-04-01 00:00:00

abstract：:Alzheimer's disease (AD) patients tend to have increased plasma levels of homocysteine. However, it is unclear whether abnormality in homocysteine levels is a primary cause of Alzheimer's disease or a disease marker. In order to investigate the relative impact of Alzheimer's disease on plasma homocysteine levels, tota...

journal_title：Neuroscience research

authors： Santiard-Baron D,Aupetit J,Janel N

更新日期：2005-12-01 00:00:00

abstract：:Sleep disturbances are common in psychiatric disorders, but the causal relationship between the two and the underlying genetic factors is unclear. The DISC1 gene is strongly linked to mood disorders and schizophrenia in a Scottish pedigree. In an earlier study we found a sleep homeostasis disturbance in a Drosophila m...

journal_title：Neuroscience research

authors： Jaaro-Peled H,Altimus C,LeGates T,Cash-Padgett T,Zoubovsky S,Hikida T,Ishizuka K,Hattar S,Mongrain V,Sawa A

更新日期：2016-11-01 00:00:00

abstract：:In 15 cats with implantations of crystalline HRP-WGA in the cerebellar nuclei and tetramethylbenzidine histochemistry, the pontine nuclei were carefully examined for presence of retrogradely labelled cells. Findings in the nucleus reticularis tegmenti pontis and the inferior olive, both known to project to the cerebel...

journal_title：Neuroscience research

authors： Brodal P,Dietrichs E,Walberg F

更新日期：1986-11-01 00:00:00

abstract：:Deficiency in n-3 fatty acids is known to disturb the release of dopaminergic neurotransmitters in rat brain. Since isomerization reduces the bioavailability of dietary fatty acids, the effect of the conversion of alpha-linolenic acid into trans alpha-linolenic acid on the dopaminergic neurotransmission was studied. R...

journal_title：Neuroscience research

authors： Acar N,Chardigny JM,Darbois M,Pasquis B,Sébédio JL

更新日期：2003-04-01 00:00:00

abstract：:Recent advances in our understanding of brain function have come from using light to either control or image neuronal activity. Here we describe an approach that combines both techniques: a micromirror array is used to photostimulate populations of presynaptic neurons expressing channelrhodopsin-2, while a red-shifted...

journal_title：Neuroscience research

authors： Tsuda S,Kee MZ,Cunha C,Kim J,Yan P,Loew LM,Augustine GJ

更新日期：2013-01-01 00:00:00

abstract：:Dynamic binding of different brain areas is critical for various cognitive functions. The thalamic reticular nucleus (TRN) is a GABAergic nucleus that constrains information flow through thalamocortical loop by providing inhibitory innervation to the thalamus. In this review, I summarize anatomical and single-cell-lev...

journal_title：Neuroscience research

authors： Takata N

更新日期：2020-07-01 00:00:00

abstract：:In the vertebrate nervous system, glutamate (Glu) receptors are generally known to cause depolarizing responses. We report here a novel type of Glu response in Purkinje neurons of mouse cerebellar slices, namely glutamate-induced hyperpolarization (GH). This response is not due to activation of inhibitory interneurons...

journal_title：Neuroscience research

authors： Inoue T,Miyakawa H,Ito K,Mikoshiba K,Kato H

更新日期：1992-12-01 00:00:00

abstract：:Short-interval intracortical inhibition (SICI) acting on the first dorsal interosseus was measured using paired-pulse transcranial magnetic stimulation (interstimulus interval=2ms) in samples of young and healthy older subjects and correlated with manual dexterity measured with the Purdue Pegboard test and two isometr...

journal_title：Neuroscience research

authors： Marneweck M,Loftus A,Hammond G

更新日期：2011-08-01 00:00:00

abstract：:To study the differences between peripheral nerve (PN) and embryonic homologous CNS structures as a conduit for CNS axons, spinal cord segments in neonatal rats were removed at the mid-thoracic level and PN or embryonic spinal cord (ESC) segments were grafted into the vacancy. Neural connections across the graft were ...

journal_title：Neuroscience research

authors： Asada Y,Kawaguchi S,Hayashi H,Nakamura T

更新日期：1998-07-01 00:00:00

abstract：:In previous studies we provided evidence for changes in prolactin (PRL) receptor levels in the male rat brain after continuously infusing morphine using subcutaneously implanted miniosmotic pumps. In this work we have studied the binding of PRL in the male rat brain following morphine administration by both subcutaneo...

journal_title：Neuroscience research

authors： Lai Z,Zhai Q,Liu Z,Roos P,Nyberg F

更新日期：1995-10-01 00:00:00

abstract：:Xenopus oocytes injected with messenger RNA extracted from rat brain are induced to acquire a variety of neurotransmitter receptors and voltage-operated membrane channels. Activation of the receptors to serotonin, acetylcholine (muscarinic) and glutamate elicits oscillatory membrane currents carried by chloride ions. ...

journal_title：Neuroscience research

authors： Parker I,Gundersen CB,Miledi R

更新日期：1985-08-01 00:00:00

abstract：:We excised the dorsal part of the optic vesicle of chick embryos at stages 13-14 (embryonic day 2). The remainder of the optic vesicle reoganized and developed a small eye. This study was undertaken to determine how locus specificity is kept within the reorganized retina. The projection pattern from the reorganized ey...

journal_title：Neuroscience research

authors： Matsuno T,Itasaki N,Ichijo H,Nakamura H

更新日期：1992-10-01 00:00:00

abstract：:To evaluate recovery function of and effects of hyperventilation (HV) on high-frequency oscillations (HFOs) of median nerve somatosensory evoked potential (SEP), we recorded SEPs in 8 Parkinson's disease (PD) patients with enlarged HFOs, 4 myoclonus epilepsy (ME) patients and 10 healthy volunteers (N). SEP was recorde...

journal_title：Neuroscience research

authors： Mochizuki H,Machii K,Terao Y,Furubayashi T,Hanajima R,Enomoto H,Uesugi H,Shiio Y,Kamakura K,Kanazawa I,Ugawa Y

更新日期：2003-08-01 00:00:00

abstract：:In acute decerebrate cats, medial pontine reticular formation (mPRF) and the mesencephalic locomotor region (MLR) were stimulated and their stimulus effects upon 250 medullary reticulospinal neurons (RSNs) were studied. One hundred and twenty-six RSNs were mono- and disynaptically activated. From the response patterns...

journal_title：Neuroscience research

authors： Iwakiri H,Oka T,Takakusaki K,Mori S

更新日期：1995-08-01 00:00:00

abstract：:We previously showed that our neural stem sphere (NSS) method promotes the neuronal differentiation of mouse, monkey and human embryonic stem (ES) cells. Here we analyzed changes in expression of marker genes and proteins during neuronal differentiation. When cultured in astrocyte-conditioned medium (ACM) under free-f...

journal_title：Neuroscience research

authors： Otsu M,Sai T,Nakayama T,Murakami K,Inoue N

更新日期：2011-04-01 00:00:00

abstract：:During brain development, neural stem cells change their competency to give sequential rise to neurons and glial cells. Expression of the basic helix-loop-helix (bHLH)-type cell-fate determination factors Ascl1, Olig2, and Hes1 is oscillatory in neural stem cells. Conversely, sustained expression of these factors medi...

journal_title：Neuroscience research

authors： Kageyama R,Shimojo H,Ohtsuka T

更新日期：2019-01-01 00:00:00

abstract：:It has previously been shown that when a target is moved, cats can change the direction of ongoing target-reaching with brief latency suggesting a tectal relay. Switching of target-reaching has now been investigated after spinal lesions: (1) dorsally in C5 interrupting cortico- (CS) and rubrospinal (RS) fibres to fore...

journal_title：Neuroscience research

authors： Alstermark B,Górska T,Lundberg A,Pettersson LG,Walkowska M

更新日期：1987-10-01 00:00:00

abstract：:Pseudorabies virus (PrV) as a neuronal tracer was microinjected into the concave surface of the puppy's left pinna to establish the morphological basis of somato-visceral linkage. The virus infected neurons were detected by FITC conjugated with polyclonal swine anti-PrV serum. Labelled neurons were localized in: (1) t...

journal_title：Neuroscience research

authors： Chien CH,Shieh JY,Liao MH,Ling EA,Wen CY

更新日期：1998-02-01 00:00:00

abstract：:In the past few years, the plasticity of the regional specification of the CNS has been widely debated on the results from in utero transplantation. Two different results are reported with this transplantation method. One is that the distribution of transplanted cells is dependent on the donor origin, and the other is...

journal_title：Neuroscience research

authors： Honda S,Toda K,Tozuka Y,Yasuzawa S,Iwabuchi K,Tomooka Y

更新日期：2007-10-01 00:00:00

abstract：:We previously found that ginsenoside Rd (GSRd), one of the main active ingredients in Panax Ginseng, attenuates H(2)O(2)-induced oxidative injury in PC12 cells. Mounting evidence suggests that the oxidative stress is crucially involved in the pathophysiologic process of ischemia. In the present study, we examined the ...

journal_title：Neuroscience research

authors： Ye R,Li N,Han J,Kong X,Cao R,Rao Z,Zhao G

更新日期：2009-07-01 00:00:00

abstract：:GABAergic characteristics of transcallosal activity of cat pyramidal tract neurons (PTNs) and non-PTNs (nPTNs) were studied with stressing on GABAB receptors. PTNs and nPTNs were further classified into group 1 (< 10 ms) and group 2 (> 10 ms) based on the latency upon transcallosal stimulation. However, mainly the res...

journal_title：Neuroscience research

authors： Chowdhury SA,Kawashima T,Konishi T,Matsunami K

更新日期：1996-12-01 00:00:00