Abstract:
:A multibarreled glass-coated tungsten microelectrode suitable for single-unit recording and iontophoresis in chronically behaving animals is described. The microelectrode was stiff enough to pass through the dura matter of behaving monkeys, and can be applied as a microiontophoretic electrode. The electrode is easy to build and usable in stabilized conditions after repeated penetrations.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Li BM,Mei ZT,Kubota Kdoi
10.1016/0168-0102(90)90023-8subject
Has Abstractpub_date
1990-07-01 00:00:00pages
214-9issue
3eissn
0168-0102issn
1872-8111pii
0168-0102(90)90023-8journal_volume
8pub_type
杂志文章abstract::In previous studies we provided evidence for changes in prolactin (PRL) receptor levels in the male rat brain after continuously infusing morphine using subcutaneously implanted miniosmotic pumps. In this work we have studied the binding of PRL in the male rat brain following morphine administration by both subcutaneo...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00953-1
更新日期:1995-10-01 00:00:00
abstract::Injury to the central nervous system causes glial reactions, which eventually lead to the formation of a glial scar and inhibit axonal regeneration. The present study aimed to reduce the extent of glial scar formation in injured cerebral cortex using heparin hexasaccharide (6-mer) and octasaccharide (8-mer). A single ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2004.01.007
更新日期:2004-05-01 00:00:00
abstract::Sizes of neuronal somata in the cat cervical dorsal root ganglia were determined at different levels (C1-C8). The average value and class distribution of mean cell diameter were analyzed. The ganglia from C1 to C5 could be clearly distinguished from those at levels of brachial plexus afferents (C6-C8) with respect to ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(90)90009-4
更新日期:1990-02-01 00:00:00
abstract::Recent advances in our understanding of brain function have come from using light to either control or image neuronal activity. Here we describe an approach that combines both techniques: a micromirror array is used to photostimulate populations of presynaptic neurons expressing channelrhodopsin-2, while a red-shifted...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2012.11.006
更新日期:2013-01-01 00:00:00
abstract::How the nervous system controls the sensation and memory of information from the environment is an essential question. The nematode Caenorhabditis elegans is a useful model for elucidating neural information processing that mediates sensation and memory. The entire nervous system of C. elegans consists of only 302 neu...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/j.neures.2013.03.008
更新日期:2013-07-01 00:00:00
abstract::NMDA receptors play an important functional role in the neuron excitability and plasticity. The conditions and consequences of their activation are of interest for many neuroscientists. This investigation was designed to explore an activation of the NMDA receptors of frog tectal neurons in vivo by a burst of spikes of...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2005.12.014
更新日期:2006-04-01 00:00:00
abstract::The subiculum is one of output structures of the hippocampal formation and plays a pivotal role in learning and memory. Because its morphological features are less investigated than those of the hippocampus proper, we explored the internal structure of the rat subiculum using immunohistochemistry. The septal subiculum...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2019.02.001
更新日期:2020-01-01 00:00:00
abstract::In an attempt to test the possibility that sino-aortic baroreceptors may mediate the previously reported stress response in hypothalamic magnocellular neurosecretory cell activity in rats, effects of deafferentation of sino-aortic baroreceptors on plasma levels of vasopressin and oxytocin after fear-related emotional ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(92)90059-l
更新日期:1992-04-01 00:00:00
abstract::Chronic muscular limb pain requires the adoption of motor patterns distinct from the classic ipsilateral flexion, crossed extension and corresponding reciprocal inhibitions to acute exteroceptive stimulation. Using selective chemical activation of group III/IV afferents in gastrocnemius-soleus (GS) muscles we investig...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2015.01.003
更新日期:2015-06-01 00:00:00
abstract::The present study was performed to determine whether the voltage gated Cl- channel (CLC) expression is altered in the hippocampus of seizure sensitive (SS) gerbils, and to identify the strong fast paired-pulse inhibition in the dentate gyrus of SS gerbils is associated with altered CLC expression. In the hippocampal p...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2004.09.010
更新日期:2005-01-01 00:00:00
abstract::Using standard intracellular recording techniques 38 nonpyramidal cells or interneurons have been sampled in hippocampal slices of the rat. Among 38 physiologically identified interneurons, all 27 cells labeled with biocytin were morphologically demonstrated to be nonpyramidal and nongranule cells. The vast majority o...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90013-2
更新日期:1994-02-01 00:00:00
abstract::Repetitive transcranial magnetic stimulation (rTMS), which could improve learning and memory, is widely used in psychiatry and neurology as a therapeutic approach. There are few studies reporting effective countermeasures to cognition decline in astronauts during space flight. Accordingly, we examined whether rTMS was...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2019.04.002
更新日期:2020-04-01 00:00:00
abstract::The disposition of the facial vibrissae of the mouse is represented as a matrix-like array of cell aggregates in rows and columns at every station of the whisker-to-barrel pathway. In order to evaluate the role of each station in this pathway, lesions were made in the facial vibrissae of the mystacial group on P0-P3, ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00969-Z
更新日期:1995-11-01 00:00:00
abstract::Almost all organisms on Earth have an internal biological clock, known as the circadian clock. This clock system drives robust oscillations in metabolism, physiology, and behavior, such as hormone secretions, blood pressure, and sleep/wake cycles, with a period of approximately 24h. In mammals, circadian rhythms are g...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2017.10.007
更新日期:2018-04-01 00:00:00
abstract::Many studies on long-term potentiation (LTP) in hippocampal region CA1 focus on receptor-mediated events that are often presumed to be linked to postsynaptic processes. Whereas it is now well-known that LTP consists of multiple components involving increases in postsynaptic responsiveness as well as enhanced presynapt...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00986-8
更新日期:1996-01-01 00:00:00
abstract::The Madagascan lesser hedgehog tenrec was investigated to get insight into the areal evolution of the hippocampal formation in mammals with poorly differentiated brains. The hippocampal subdivisions were analyzed using cyto- and chemoarchitectural criteria; long associational and commissural connections were demonstra...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(01)00288-7
更新日期:2001-11-01 00:00:00
abstract::Slow disjunctive eye movement similar to ocular convergence was evoked by microstimulation in parts of the lateral suprasylvian area (LSA) in alert cats. A tungsten-in-glass microelectrode was used for stimulation, and eye movement was monitored using the magnetic search coil method. The velocity-versus-amplitude rela...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(91)90120-n
更新日期:1991-10-01 00:00:00
abstract::Close relationships between the nervous system and immune systems at molecular levels have now become evident. Receptors for CDF/LIF and CNTF, i.e., factors which play important roles in the nervous system, share a close structural similarity to those for IL-6, which is a molecule acting in the immune system. Receptor...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/0168-0102(92)90001-s
更新日期:1992-11-01 00:00:00
abstract::We previously demonstrated that metabotropic glutamate receptor-subtype 1 knockout [mGluR1 (-/-)] mice showed ataxic gait, deficient long-term depression and impaired synapse elimination and these phenotypes were rescued by introduction of an mGluR1 transgene with Purkinje cell-specific promoter (mGluR1-rescue mice). ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2006.12.014
更新日期:2007-04-01 00:00:00
abstract::Basigin (Bsg) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. Chicken Bsg (HT7/neurothelin/ 5A11) is expressed in neuroblasts, but disappears from neurons after a specific stage of cytodifferentiation, and becomes restrictedly expressed in the capillary endothelium in the adult brain. We s...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(97)00119-3
更新日期:1998-01-01 00:00:00
abstract::Rhotekin, an effector of Rho, is highly expressed in the brain but its function(s) in neurons is almost unknown. In an attempt to define the properties of Rhotekin in neuronal cells, we focused on its interaction with polarity-related molecules. In the present study, we identified a PDZ protein, Lin-7B, as a binding p...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2006.08.003
更新日期:2006-12-01 00:00:00
abstract::Visual-spatial navigation in familiar and unfamiliar environments is an essential requirement of daily life. Animal studies indicated the importance of the hippocampus for navigation. Neuroimaging studies demonstrated gender difference or strategies dependent difference of neural substrates for navigation. Using funct...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2006.04.009
更新日期:2006-08-01 00:00:00
abstract::Growth hormone (GH) is a pleiotropic hormone that exerts important functions in the control of brain development as well as in the regulation neuronal differentiation and function, together with several behavioral and psychological effects that have been linked to its modulatory actions on brain neurotransmitters. In ...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/j.neures.2013.03.014
更新日期:2013-08-01 00:00:00
abstract::We generated a transgenic rat strain with a missense mutation in V286L (V286L-TG), in the gene encoding the neuronal nicotinic acetylcholine receptor β2 subunit (CHRNB2) found in patients with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). To confirm that V286L-TG rats exhibit seizures similar to those o...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2015.06.003
更新日期:2015-11-01 00:00:00
abstract::Neuronal degeneration appears to be associated with changes in anti-ubiquitin immunoreactivity (UIR). To elucidate the relationship between the two events, we examined the time course of changes in UIR in pyramidal neurons of hippocampal organotypic cultures following exposure to an excitotoxin, N-methyl-D-aspartate (...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00911-c
更新日期:1995-07-01 00:00:00
abstract::Action potentials, when arriving at presynaptic terminals, elicit Ca(2+) influx through voltage-gated Ca(2+) channels. Intracellular [Ca(2+)] elevation around the channels subsequently triggers synaptic vesicle exocytosis and also induces various protein reactions that regulate vesicle endocytosis and recycling to pro...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/j.neures.2012.02.012
更新日期:2012-05-01 00:00:00
abstract::Eye movements were induced by stimulating the ventral bank of the anterior ectosylvian sulcus (AES) of chloralose-anesthetized cats. Intracortical microstimulation of this cortex evoked centering movements of both eyes. The latency of eye movement was 45 ms (range 40-60 ms) and the intensity of stimulation was 33 micr...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(89)90056-4
更新日期:1989-11-01 00:00:00
abstract::Dopamine is a major neurotransmitter in the carotid body of several animal species and its functional role at the level of peripheral arterial chemoreflex pathway is attributed to the presence of the dopamine D2-receptors. We present evidence that the dopamine D1-receptor mRNA is also expressed in the carotid body of ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(98)00033-9
更新日期:1998-06-01 00:00:00
abstract::We previously reported that the gamma gamma-isozyme of enolase, NSE), one of the glycolytic enzymes, promoted the survival of embryonic rat neocortical neurons in culture, but alpha alpha-isozyme (non-neuronal enolase) had no effect. In the present study, the neurotrophic effects of NSE on cultured mesencephalic and s...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)00849-b
更新日期:1995-01-01 00:00:00
abstract::To investigate how motor programs can be modified by sensory inputs we recorded kinematic and EMG patterns from normal human subjects performing well-practised wrist flexion movements in response to an auditory tone. On random trials unexpected wrist perturbations were introduced at varying times after the signal to m...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(90)90062-j
更新日期:1990-06-01 00:00:00