Abstract:
:In the rat striatum numerous secretagogin (SCGN) positive neurons were scattered. They were heterogeneous in their morphological and chemical properties. We examined the colocalization of SCGN with known four interneuron markers, parvalbumin (PV), calretinin (CR), nitric oxide synthase (NOS) and choline acetyl transferase (ChAT). 60-70% of SCGN positive striatal neurons contained either PV or CR or ChAT, but none contained NOS. On the other hand the remaining 30-40% expressed none of these markers, most of which were GAD positive. The present study indicates that there are hitherto unknown groups of striatal interneurons in the rat striatum.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Kosaka T,Yasuda S,Kosaka Kdoi
10.1016/j.neures.2017.01.004subject
Has Abstractpub_date
2017-06-01 00:00:00pages
53-60eissn
0168-0102issn
1872-8111pii
S0168-0102(16)30195-Xjournal_volume
119pub_type
杂志文章abstract::Vestibular nuclear neurons that mediate horizontal canal signals to the ipsilateral medial rectus motoneurons were explored in anesthetized and decerebrate rabbits. These neurons were identified by four criteria: (1) they were activated monosynaptically by ipsilateral vestibular nerve stimulation and (2) antidromicall...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(85)90016-1
更新日期:1985-08-01 00:00:00
abstract::The actin cytoskeleton plays a critical role in the cellular morphological changes. Its organization is essential for neurite extension and synaptogenesis under the processes of neuronal development. Recently, neural Wiskott-Aldrich syndrome protein (N-WASP) and WASP family verprolin-homologous protein (WAVE) have bee...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2006.09.007
更新日期:2006-12-01 00:00:00
abstract::To examine the role of GABA on prefrontal neuronal activity in the control of behavior, a GABA(A) receptor antagonist, bicuculline methiodite (BMI), was iontophoretically applied to prefrontal neurons while monkeys performed a visual reaction time task. Iontophoretic application of BMI uncovered "task-related" activit...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(00)00204-2
更新日期:2001-01-01 00:00:00
abstract::Carbon monoxide (CO) is a gas that can permeate biological membranes and it has been suggested that the gas plays a signaling role in the brain by activating soluble guanylyl cyclase (sGC). CO is generated by heme oxygenase during the conversion of heme to biliverdin. In this study, we raised an antiserum against the ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(96)01018-8
更新日期:1996-03-01 00:00:00
abstract::The hypothalamic paraventricular nuclei (PVN) inhibits spinal nociception. Furthermore, projections from the PVN to other structures related to pain modulation exist, but a functional interaction has not yet been fully demonstrated. As an initial approach, we show here that PVN electric stimulation with the same param...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2015.04.004
更新日期:2015-09-01 00:00:00
abstract::Post-traumatic stress disorder (PTSD) is an anxiety disorder that occurs following an unexpected exposure to a severe psychological event. A history of a brief trauma is reported to affect a risk for future PTSD development; however, little is known about the mechanisms by which a previous trauma exposure drives the s...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2015.02.001
更新日期:2015-06-01 00:00:00
abstract::Neurons in the inferior temporal (IT) cortex respond not only to the shape, color or texture of objects, but to the horizontal positional disparity of visual features in the right and left retinal images. IT neurons with similar shape selectivity cluster in columns. In this study, we examined how IT neurons are spatia...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2003.10.008
更新日期:2004-02-01 00:00:00
abstract::The distribution of a live attenuated herpes simplex virus (betaH1)-mediated gene delivery into the central nervous system (CNS) was regulated by growth inhibition with ganciclovir (GCV) and the effect of this transgene expression system on the physiologic response was characterized by the acoustic startle response an...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(02)00235-3
更新日期:2003-02-01 00:00:00
abstract::Recent studies have compared default-mode network (DMN) connectivity in different arousal levels to investigate the relationship between consciousness and DMN. The comparison between the DMN in rapid eye movement (REM) sleep with that in non-REM (NREM) sleep is useful for revealing the relationship between arousal lev...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2010.12.018
更新日期:2011-04-01 00:00:00
abstract::We newly developed an infrared video-oculographic system for on-line tracking of the eye position in awake and head-fixed mice, with high temporal resolution (240 Hz). The system consists of a commercially available high-speed CCD camera and an image processing software written in LabVIEW run on IBM-PC with a plug-in ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2004.02.002
更新日期:2004-05-01 00:00:00
abstract::Axonal transport is the specialized and well-developed intracellular transport system for regulated and/or long-distance transport based on generalized cellular machineries. Among them, slow axonal transport conveys cytoplasmic proteins. The motor molecule, the nature of transporting complex and the transport regulati...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/j.neures.2003.08.005
更新日期:2003-12-01 00:00:00
abstract::In the present study, the ability of 5-hydroxytryptamine(2C) (5-HT(2C)) receptors in the hippocampus to enhance locomotor activity in rats was investigated by local infusion. Intraperitoneal injection of the selective 5-HT(2C) antagonist SB 242084 (1 mg/kg) significantly increased rats motor activity, while the effect...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(01)00215-2
更新日期:2001-05-01 00:00:00
abstract::Both amyloid-β peptide (Aβ) deposition and neuroinflammation are considered to be early events that play pivotal roles in Alzheimer's disease (AD) pathogenesis and its associated cognitive impairment. Prophylactic anti-Aβ active immunotherapy is a promising therapeutic strategy for AD, if the Aβ-specific autoimmune re...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2017.01.003
更新日期:2017-06-01 00:00:00
abstract::The neurodegenerative process in Parkinson's disease (PD) is accompanied by the presence of a neuroinflammatory response, which has been suggested as one of the principal components involved in PD progression. In this report we assessed the inflammatory potential of alpha-synuclein, a protein central to PD pathogenesi...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2010.12.020
更新日期:2011-04-01 00:00:00
abstract::Residues 61-95 of the non-amyloid component (NAC(61-95)) domain of alpha-synuclein are responsible for the aggregation and neurotoxicity of this protein. This study evaluated the effect of N((omega))-nitro-l-arginine methyl ester (l-NAME), a nitric oxide synthase inhibitor, on the behavior of rats bilaterally injected...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2009.11.002
更新日期:2010-02-01 00:00:00
abstract::This study was to aim at investigating the potential interaction for the serotonin receptor gene (5-HTR) 2A and serotonin transporter gene (5-HTTLPR) polymorphisms in the development of schizophrenia, as well as the interaction of the two polymorphisms in relation with symptomatology, family history, age of onset and ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2005.03.006
更新日期:2005-06-01 00:00:00
abstract::This experiment tested the effect of haloperidol on the sympathetic and thermogenic effects induced by orexin A. The firing rates of the sympathetic nerves to interscapular brown adipose tissue (IBAT), along with IBAT and colonic temperatures and heart rate were monitored in urethane-anesthetized male Sprague-Dawley r...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(02)00191-8
更新日期:2003-01-01 00:00:00
abstract::We examined the number and size of motoneurons and myelinated nerve fibers innervating the medial gastrocnemius (MG) muscle in the hindlimb of rats that were subjected to swimming for 10 months (30 min, 3 days/week) from 17 to 27 months of age. The number of MG motoneurons in exercised aged rats was slightly, but not ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(98)00026-1
更新日期:1998-05-01 00:00:00
abstract::To study the contribution of retinal and cortical afferents to the patterns of glutamate- and homocysteate-like immunoreactivities in dorsal lateral geniculate, combined retinal and cortical ablations were performed in rats. In controls, glutamate immunoreactivity was in terminal-like dots and neurons. Homocysteate im...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(97)01162-0
更新日期:1997-04-01 00:00:00
abstract::A single-pulse TMS to the human motor cortex (M1) influences reaction time (RT). We may summarize from previous studies where different groups of subjects participated in various types of RT tasks that TMS above motor threshold (MT) delays RT, whereas TMS below MT shortens RT and that these RT changes depends on TMS t...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2004.08.002
更新日期:2004-12-01 00:00:00
abstract::The human cerebral neocortex is divided into six layers consisting of specific neuronal cell types and connections. To determine the distribution of cortical neurons during early development, we examined the expressions of layer-specific markers in human midterm fetal brains. Layer V marker ZNF312 is expressed in most...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2010.05.007
更新日期:2010-09-01 00:00:00
abstract::Single units of the adrenal sympathetic nerve (n = 46) were dissected and characterized with respect to tonic discharge and response to cutaneous and baroreceptor stimulation. The frequency of tonic discharge averaged 1.6 Hz and cardiovascular rhythmic modulation was observed in 53% of the units. The stimuli employed ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(84)80008-5
更新日期:1984-04-01 00:00:00
abstract::Many forms of psychopathology and/or psychiatric illness can occur through the pathways of altered environmental sensitivity, impulsivity, social functioning, and anxious responding. While these traits are also heritable, environmental conditions are known to play a critical role. The genetic factors that contribute t...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/j.neures.2015.08.001
更新日期:2016-01-01 00:00:00
abstract::We generated a transgenic rat strain with a missense mutation in V286L (V286L-TG), in the gene encoding the neuronal nicotinic acetylcholine receptor β2 subunit (CHRNB2) found in patients with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). To confirm that V286L-TG rats exhibit seizures similar to those o...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2015.06.003
更新日期:2015-11-01 00:00:00
abstract::Effects of 1-naphthyl acetyl spermine (NASPM), a synthetic analogue of Joro spider toxin (JSTX), on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors were studied in cultured rat hippocampal neurons using the whole-cell patch clamp technique. A population of cultured neurons had ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(97)00067-9
更新日期:1997-09-01 00:00:00
abstract::Neonatal Brachial Plexus Palsy (NBPP) may lead to permanent impairment of arm function. As NBPP occurs when central motor programs develop, these may be ill-formed. We studied elbow flexion and motor imagery with fMRI to search for abnormal motor programming. We compared the cortical activity of adults with conservati...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2017.05.001
更新日期:2017-10-01 00:00:00
abstract::Almost all organisms on Earth have an internal biological clock, known as the circadian clock. This clock system drives robust oscillations in metabolism, physiology, and behavior, such as hormone secretions, blood pressure, and sleep/wake cycles, with a period of approximately 24h. In mammals, circadian rhythms are g...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2017.10.007
更新日期:2018-04-01 00:00:00
abstract::To elucidate the interaction between nitric oxide (NO) and substance P (SP) in neurogenic inflammatory responses, we measured the change in the degree of Evans blue leakage and NO levels in perfusate from the subcutaneous space in the rat instep following noxious heat stimulation (47 degrees C for 30 min). Furthermore...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(99)00107-8
更新日期:2000-01-01 00:00:00
abstract::In many studies on functional neuroimaging, change in local cerebral blood flow induced by sensory stimulation (evoked LCBF) is used as a marker for change in cortical neuronal activity, although a full description of the relationship between the evoked LCBF and neuronal activity has not been given. The purpose of thi...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(01)00236-x
更新日期:2001-07-01 00:00:00
abstract::Afferent neurons entering the central nervous systems of vertebrates and invertebrates receive presynaptic inhibition on their axon terminals. This usually involves an increase in membrane conductance (shunting) and depolarization (primary afferent depolarization, PAD). In arachnids and crustaceans the peripherally lo...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2006.03.002
更新日期:2006-06-01 00:00:00