Unmasking of silent "task-related" neuronal activity in the monkey prefrontal cortex by a GABA(A) antagonist.

abstract：:The subgranular zone (SGZ) in the dentate gyrus contains radial astrocytes, known as Type-1 or Type-B cells, which generate neuroblasts (Type-2 cells or Type-D cells) that give rise to granular neurons. Stress increases glucocorticoid levels that target SGZ and modify the proliferation and apoptosis of hippocampal cel...

journal_title：Neuroscience research

authors： Gonzalez-Perez O,Chavez-Casillas O,Jauregui-Huerta F,Lopez-Virgen V,Guzman-Muniz J,Moy-Lopez N,Gonzalez-Castaneda RE,Luquin S

更新日期：2011-07-01 00:00:00

abstract：:Event-related potentials (ERPs) during an auditory discrimination task were recorded both on the surface and at a depth of the auditory cortex in rats. Ten-kilohertz rare and 5-kHz frequent tones were used with the probabilities of 0.2 and 0.8. Lever pressing within 2 s, following the onset of the rare tone, was rewar...

journal_title：Neuroscience research

authors： Iwanami A,Shinba T,Sumi M,Ozawa N,Yamamoto K

更新日期：1994-11-01 00:00:00

abstract：:Considerable evidence suggests that an N-methyl-D-aspartate (NMDA) receptor plays a crucial role in memory and cognitive function. To identify the role of this receptor in higher functions of the brain, we delivered antisense oligonucleotides against an NMDA-NR1 subunit (NR1) to the hippocampus in rats using the HVJ-l...

journal_title：Neuroscience research

authors： Inada K,Ishigooka J,Anzai T,Suzuki E,Miyaoka H,Saji M

更新日期：2003-04-01 00:00:00

abstract：:Long-term depression at parallel fiber-Purkinje cell synapses plays a principal role in learning in the cerebellum, which acts as a supervised learning machine. Recent experiments demonstrate various forms of synaptic plasticity at different sites within the cerebellum. In this article, we take into consideration syna...

journal_title：Neuroscience research

authors： Yamazaki T,Lennon W

更新日期：2019-11-01 00:00:00

abstract：:This study was designed to evaluate the anticonvulsant effects of imperatorin (a furanocoumarin isolated from fruits of Angelica archangelica) in the mouse maximal electroshock seizure threshold model. The threshold for electroconvulsions in mice was determined at several times: 15, 30, 60 and 120 min after i.p. admin...

journal_title：Neuroscience research

authors： Luszczki JJ,Glowniak K,Czuczwar SJ

更新日期：2007-09-01 00:00:00

abstract：:To identify the roles of VGCC subtypes in damages/impairs of inhibitory transmission during epileptogenesis, we investigated temporal- and spatial-specific alterations in voltage-gated Ca(2+) channel (VGCC) immunoreactivities within parvalbumin (PV, a Ca(2+) binding protein) positive neurons in the rat hippocampus fol...

journal_title：Neuroscience research

authors： Kim JE,Kwak SE,Kim DS,Won MH,Choi HC,Song HK,Kim YI,Kang TC

更新日期：2007-03-01 00:00:00

abstract：:Zinc is one of trace elements that play essential roles in several cell functions, and is unquestionably important to the normal health and function of the central nervous system. Growing evidence suggests that Zn(2+) can become a pathogenic agent in certain neurological disease states, such as ischemia, seizures, and...

journal_title：Neuroscience research

authors： Tian Y,Yang Z,Zhang T

更新日期：2010-11-01 00:00:00

abstract：:The purpose of this study was to investigate electrophysiological correlates related to the recognition of repeated faces in the intact human by means of event-related brain potentials (ERPs). A group of young healthy adults performed a continuous face recognition task, in which 240 unfamiliar faces were flashed upon ...

journal_title：Neuroscience research

authors： Münte TF,Brack M,Grootheer O,Wieringa BM,Matzke M,Johannes S

更新日期：1997-07-01 00:00:00

abstract：:A group of brain acid-soluble proteins (BASPs) is preliminarily characterized. In some respects BASPs are similar to high mobility group (HMG) proteins, but in contrast to HMG, all BASPs are very acidic (pI 4.4-4.6) and show abnormal mobility during SDS-PAGE electrophoresis. BASP2-1 and BASP2-2 are identified as the t...

journal_title：Neuroscience research

authors： Mosevitsky MI,Novitskaya VA,Plekhanov AYu,Skladchikova GYu

更新日期：1994-03-01 00:00:00

abstract：:Prenatal exposure to nicotine (PNE) has been associated with a myriad of physiological, cognitive, and behavioral effects in the developing offspring. In this study, CD-1 dams were given injections of nicotine or control vehicle throughout gestation and their offspring were raised to 6 months of age. Adult mice were a...

journal_title：Neuroscience research

authors： Santiago SE,Huffman KJ

更新日期：2014-02-01 00:00:00

abstract：:We investigated brain activity in 3-5-year-old preschoolers as they listened to connected speech stimuli in Japanese (first language), English (second language), and Chinese (a rarely exposed, foreign language) using near-infrared spectroscopy. Unlike the younger preschoolers who had been exposed to English for almost...

journal_title：Neuroscience research

authors： Hidaka S,Shibata H,Kurihara M,Tanaka A,Konno A,Maruyama S,Gyoba J,Hagiwara H,Koizumi M

更新日期：2012-05-01 00:00:00

abstract：:Changes in synaptic efficacy at the parallel fiber (PF)-Purkinje cell (PC) synapse are postulated to be a cellular basis for motor learning. Although long-term efficacy changes lasting more than an hour at this synapse, i.e., long-term potentiation and depression, have been extensively studied, relatively short lastin...

journal_title：Neuroscience research

authors： Goto J,Inoue T,Kuruma A,Mikoshiba K

更新日期：2006-05-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by progressive degeneration of motoneurons. We have demonstrated that hepatocyte growth factor (HGF) attenuates loss of both spinal and brainstem motoneurons of ALS model mice expressing mutated human SOD1(G93A) (G93A). This study was designed to ass...

journal_title：Neuroscience research

authors： Kadoyama K,Funakoshi H,Ohya-Shimada W,Nakamura T,Matsumoto K,Matsuyama S,Nakamura T

更新日期：2009-10-01 00:00:00

abstract：:Using a confocal laser scanning microscope (CLSM) and an electron microscope, we investigated the organization of the main olfactory bulb (MOB) of tenrecs, which were previously included into insectivores but now considered to be in a new order "Afrosoricida" in the superclade 'Afrotheria'. We confirmed that the overa...

journal_title：Neuroscience research

authors： Kosaka K,Künzle H,Kosaka T

更新日期：2005-12-01 00:00:00

abstract：:The facilitatory masseteric muscle response (FMR) elicited by polyurethane foam strip application between the opposing molars during cortically-induced rhythmic jaw movements (CRJMs) was induced earlier than masticatory force onset. The occurrence of this early response of the FMR (e-FMR) could not be explained by a s...

journal_title：Neuroscience research

authors： Komuro A,Masuda Y,Iwata K,Kobayashi M,Kato T,Hidaka O,Morimoto T

更新日期：2001-01-01 00:00:00

abstract：:The synthesis of glial-fibrillary acidic protein (GFAP) or the re-expression of progenitor markers such as Nestin increases in reactive astrocytes after brain ischemia. We investigated the dynamics of reactive astrocytes after transient focal brain ischemia by examining the expression of Musashi1 (Msi1), an RNA-bindin...

journal_title：Neuroscience research

authors： Oki K,Kaneko N,Kanki H,Imai T,Suzuki N,Sawamoto K,Okano H

更新日期：2010-04-01 00:00:00

abstract：:To identify corticotropin releasing factor (CRF)- and galanin (GAL)-containing neurons projecting to the median eminence, a retrograde tracing method with True blue was combined with a double-staining method. It was demonstrated that some True blue-labeled CRF neurons in the paraventricular nucleus were also immunorea...

journal_title：Neuroscience research

authors： Niimi M,Takahara J,Kawanishi K

更新日期：1992-09-01 00:00:00

abstract：:Light-induced changes in the input resistance (Rin) of external, luminosity (i.e. H1) type horizontal cell (HC) perikarya were studied by the bridge-balance method in light-adapted and dark-adapted retinae of carp. Changes in input resistance (delta Rin) induced by short-(460 nm) and long-wavelength (674 nm) flashes, ...

journal_title：Neuroscience research

authors： Furukawa T,Yamada M,Petruv R,Djamgoz MB,Yasui S

更新日期：1997-01-01 00:00:00

abstract：:Whole-cell recordings were performed to examine the morphological properties of electrophysiologically classified area postrema (AP) neurons in rat brain slices. Using electrophysiological criteria, AP neurons were subdivided into three groups: (1) cells displaying both the hyperpolarization-activated cation current (...

journal_title：Neuroscience research

authors： Funahashi M,Mitoh Y,Akaike T,Matsuo R

更新日期：2006-01-01 00:00:00

abstract：:According to the amyloid hypothesis for the pathogenesis of Alzheimer's disease (AD), amyloid beta peptide (Abeta) directly affects neurons, leading to neurodegeneration and tau phosphorylation, followed by the production of paired helical filaments (PHF) in neurofibrillary tangles (NFT). To analyze the relationship b...

journal_title：Neuroscience research

authors： Takashima A,Honda T,Yasutake K,Michel G,Murayama O,Murayama M,Ishiguro K,Yamaguchi H

更新日期：1998-08-01 00:00:00

abstract：:Environmental factors during perinatal period have various effects on behavior. The present study examined the effects of prenatal stress and neonatal handling on anxiety and spatial learning of offspring. Prenatal stress increased anxiety-related behavior of adult offspring, whereas neonatal handling had no effect. I...

journal_title：Neuroscience research

authors： Akatsu S,Ishikawa C,Takemura K,Ohtani A,Shiga T

更新日期：2015-12-01 00:00:00

abstract：:This study was to aim at investigating the potential interaction for the serotonin receptor gene (5-HTR) 2A and serotonin transporter gene (5-HTTLPR) polymorphisms in the development of schizophrenia, as well as the interaction of the two polymorphisms in relation with symptomatology, family history, age of onset and ...

journal_title：Neuroscience research

authors： Pae CU,Artioli P,Serretti A,Kim TS,Kim JJ,Lee CU,Lee SJ,Lee C,Paik IH

更新日期：2005-06-01 00:00:00

abstract：:A time production test was performed in seven normal females and seven females with premenstrual syndrome (PMS). We used a time production test for six time intervals (6, 12, 24, 36, 48, 60 s). Time production tests were performed at 08:00, 14:00 and 20:00 h in the follicular, early luteal and late luteal phases (LLP)...

journal_title：Neuroscience research

authors： Morofushi M,Shinohara K,Kimura F

更新日期：2001-12-01 00:00:00

abstract：:Bacterial lipopolysaccharide (LPS) is a major component of the cell wall of gram negative bacteria contributing to the pathogenesis of bacterial infection, in particular in those diseases affecting central nervous system and reproductive tissues. The present work is an attempt to study the regulation of steroidogenic ...

journal_title：Neuroscience research

authors： Sadasivam M,Ramatchandirin B,Ayyanar A,Prahalathan C

更新日期：2014-06-01 00:00:00

abstract：:The present study was performed to determine whether the voltage gated Cl- channel (CLC) expression is altered in the hippocampus of seizure sensitive (SS) gerbils, and to identify the strong fast paired-pulse inhibition in the dentate gyrus of SS gerbils is associated with altered CLC expression. In the hippocampal p...

journal_title：Neuroscience research

authors： Kim DS,Yoo KY,Hwang IK,Jung JY,Won MH,Choi SY,Kwon OS,Seo JH,Kang TC

更新日期：2005-01-01 00:00:00

abstract：:Resveratrol shows ability to eliminate prion replication, but the exact mechanism for prion eradication was not clear yet. Our previous studies demonstrate a downregulation of brain-derived nerve growth factor (BDNF) during prion infection, meanwhile recovery of cerebral nerve growth factor (NGF) level by resveratrol ...

journal_title：Neuroscience research

authors： Hu C,Chen C,Chen J,Xiao K,Wang J,Shi Q,Ma Y,Gao LP,Wu YZ,Liu L,Xia Y,Yan P,Maimaitiming A,Zhou DH,Zhang LN,Chen ZB,Dong XP

更新日期：2021-01-01 00:00:00

abstract：:The distribution of neurofilament proteins and peripherin in the pituitary gland of the rat was studied with a panel of monoclonal and polyclonal antibodies recognizing different neurofilament subunits. In the posterior lobe, a dense plexus of neurofilament- and peripherin-immunoreactive fibers was seen. In the interm...

journal_title：Neuroscience research

authors： Bäck N,Tyynelä M,Portier MM,Virtanen I,Soinila S

更新日期：1995-06-01 00:00:00

abstract：:The recent advent of neuroimaging techniques provides an opportunity to examine brain regions related to a specific memory process such as episodic memory encoding. There is, however, a possibility that areas active during an assumed episodic memory encoding task, compared with a control task, involve not only areas d...

journal_title：Neuroscience research

authors： Fujii T,Okuda J,Tsukiura T,Ohtake H,Suzuki M,Kawashima R,Itoh M,Fukuda H,Yamadori A

更新日期：2002-12-01 00:00:00

abstract：:Disrupted-in-Schizophrenia 1 (DISC1) is a susceptibility gene for major mental illnesses, including bipolar disorder and schizophrenia. Although the roles of DISC1 in nervous system development and functions are increasingly recognized, pathophysiological mechanisms underlying a range of neuropsychiatric symptoms caus...

journal_title：Neuroscience research

authors： Flores R 3rd,Hirota Y,Armstrong B,Sawa A,Tomoda T

更新日期：2011-09-01 00:00:00

abstract：:In acute decerebrate cats, medial pontine reticular formation (mPRF) and the mesencephalic locomotor region (MLR) were stimulated and their stimulus effects upon 250 medullary reticulospinal neurons (RSNs) were studied. One hundred and twenty-six RSNs were mono- and disynaptically activated. From the response patterns...

journal_title：Neuroscience research

authors： Iwakiri H,Oka T,Takakusaki K,Mori S

更新日期：1995-08-01 00:00:00