Abstract:
:Almost all organisms on Earth have an internal biological clock, known as the circadian clock. This clock system drives robust oscillations in metabolism, physiology, and behavior, such as hormone secretions, blood pressure, and sleep/wake cycles, with a period of approximately 24h. In mammals, circadian rhythms are generated by a timing system comprised of a master pacemaker located in the suprachiasmatic nucleus (SCN) of the anterior hypothalamus, which orchestrates the clocks in the peripheral tissues. Jet lag, caused by an abrupt change of environmental light-dark cycles, induces a temporal misalignment of the output signal from SCN. We revealed that arginine vasopressin/V1 receptor signaling in the SCN plays a critical role in the resilience of the circadian clock to jet lag. I here discuss a model of SCN neuronal system under a jet lag condition.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Yamaguchi Ydoi
10.1016/j.neures.2017.10.007subject
Has Abstractpub_date
2018-04-01 00:00:00pages
57-61eissn
0168-0102issn
1872-8111pii
S0168-0102(17)30408-Xjournal_volume
129pub_type
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journal_title:Neuroscience research
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pub_type: 杂志文章,评审
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journal_title:Neuroscience research
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Neuroscience research
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2010.10.003
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2015.02.001
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2020.05.010
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(96)01060-7
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2008.03.009
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journal_title:Neuroscience research
pub_type: 杂志文章
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journal_title:Neuroscience research
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Neuroscience research
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2013.09.004
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journal_title:Neuroscience research
pub_type: 杂志文章
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journal_title:Neuroscience research
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journal_title:Neuroscience research
pub_type: 杂志文章
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2012.01.008
更新日期:2012-04-01 00:00:00
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2014.12.003
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