Abstract：
:To investigate the functional organization in the monkey inferotemporal cortex, which is the last exclusively visual area along the ventral visual cortical pathway, optical imaging based on intrinsic signals was carried out. We first conducted single-cell recordings with microelectrodes and determined the features critical for the activation of single cells. For the subsequent optical imaging, each critical feature was presented, which evoked multiple dark spots. Individual spots were approximately 0.5 mm in diameter and one of them covered the site of the electrode penetration at which the particular critical feature had been determined. The degree of stimulus selectivity varied from spot to spot, and from region to region even within a spot. Some regions were activated only by one of 12- 16 stimuli, while others by more than three stimuli. There were spots specifically activated by faces, and the position of activation spot changed gradually along the cortical surface as the stimulus face was rotated in depth. The length of the overall region along the direction of shift of these spots was approximately 1 mm. These results confirm the regional clustering of cells with similar stimulus selectivity and suggest larger units in which some parameters of object features are continuously mapped.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Wang G,Tanifuji M,Tanaka Kdoi
10.1016/s0168-0102(98)00062-5subject
Has Abstractpub_date
1998-09-01 00:00:00pages
33-46issue
1eissn
0168-0102issn
1872-8111pii
S0168-0102(98)00062-5journal_volume
32pub_type
杂志文章abstract：:Subcortical vascular dementia (SVD) is a small vessel disease with dementia that exhibits relatively uniform clinical and pathological features and constitutes approximately half of vascular dementia (VaD) cases. This subtype is further classified into Binswanger's disease and multiple lacunar infarctions. The former ...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2011.07.1820
更新日期：2011-11-01 00:00:00
abstract：:Neuronal circuits are intensively shaped depending on experiences received during developmental critical periods. How neuronal circuits are sculpted can even affect the later development of higher cognitive functions, such as vocal communication skills. Here, we propose songbirds that learn to sing from early auditory...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2018.11.002
更新日期：2019-03-01 00:00:00
abstract：:This study was designed to evaluate the anticonvulsant effects of imperatorin (a furanocoumarin isolated from fruits of Angelica archangelica) in the mouse maximal electroshock seizure threshold model. The threshold for electroconvulsions in mice was determined at several times: 15, 30, 60 and 120 min after i.p. admin...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2007.05.004
更新日期：2007-09-01 00:00:00
abstract：:DJ-1 is a multifunctional protein linked to recessively inherited Parkinson's disease (PD) due to loss of function mutations. Among its activities is anti-oxidant property leading to cytoprotection under oxidative stress conditions. A key effector of oxidant-induced cell death is the MAP3 kinase apoptosis signal-regul...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2010.04.002
更新日期：2010-07-01 00:00:00
abstract：:Recent technological progress has yielded great amounts of information about the molecular constituents of postsynaptic scaffolds in the dendritic spine. Actin filaments are major cytoskeletal elements in the dendritic spine, and they functionally interact with neurotransmitter receptors via regulatory actin-binding p...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/s0168-0102(01)00209-7
更新日期：2001-05-01 00:00:00
abstract：:A time production test was performed in seven normal females and seven females with premenstrual syndrome (PMS). We used a time production test for six time intervals (6, 12, 24, 36, 48, 60 s). Time production tests were performed at 08:00, 14:00 and 20:00 h in the follicular, early luteal and late luteal phases (LLP)...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(01)00290-5
更新日期：2001-12-01 00:00:00
abstract：:We suggest a time-varying partial correlation as a statistical measure of dynamic functional connectivity (dFC) in the human brain. Traditional statistical models often assume specific distributions on the measured data such as the Gaussian distribution, which prohibits their application to neuroimaging data analysis....
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2020.06.006
更新日期：2020-07-03 00:00:00
abstract：:While the role of creatine in preventing muscle (peripheral) fatigue for high performance athletes is well understood, its biochemical role in prevention of mental (central) fatigue is not. Creatine is abundant in muscles and the brain and after phosphorylation used as an energy source for adenosine triphosphate synth...
journal_title：Neuroscience research
pub_type： 临床试验,杂志文章
doi：10.1016/s0168-0102(02)00007-x
更新日期：2002-04-01 00:00:00
abstract：:Withdrawal may be a natural model to study craving and compulsive drug seeking, since craving can be viewed as a conditioned dysphoric state. It has been suggested that functional connectivity between brain areas may be of major value in explaining excessive craving and compulsive drug seeking by providing essential l...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2007.01.011
更新日期：2007-05-01 00:00:00
abstract：:The change in [Ca2+]i, in a retinal rod outer segment to flash and step stimuli was simulated. The present model included inward and outward calcium fluxes through cation channels and an Na-Ca-K exchanger, respectively, calcium buffers, and diffusion through the interdiskal space of cytoplasm and incisures. Under cont...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(96)01035-8
更新日期：1996-06-01 00:00:00
abstract：:The radioprotective effect of herb epimedium (or yin yang huo) extract (5 g/kg, oral administration daily for 4 weeks) on neurogenesis and cognition after acute radiation exposure with 5.5 Gy was evaluated in Balb/c mice by behavioral tests and immunohistochemical study. The results indicated that epimedium extract co...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2018.08.011
更新日期：2019-08-01 00:00:00
abstract：:To clarify a role of neuronal nitric oxide in neurovascular coupling, we performed cerebral blood flow (CBF) and cerebral metabolic rate of glucose (CMR(glc)) measurements with positron emission tomography in somatosensory-stimulated cats using a specific neuronal nitric oxide synthase inhibitor, 7-nitroindazole (7-NI...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(02)00122-0
更新日期：2002-10-01 00:00:00
abstract：:The hippocampus communicates with the neocortex via the entorhinal cortex and is thought to be critically involved in the consolidation of memories. This paper contains in vivo evidence of a projection from the hippocampal area CA1 to the entorhinal cortex. Current theories of memory formation suggest that the backpro...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2005.06.009
更新日期：2005-10-01 00:00:00
abstract：:Acute exposure to kainic acid (KA) induces neurochemical changes in dopaminergic systems in the brain and the aim of the present study was to investigate the acute toxicity of KA upon dopamine D2 receptors. Adult rats were injected intraperitoneally with either saline or 16 mg/kg KA. Brains were removed after 4 h. Mem...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(97)00130-2
更新日期：1998-03-01 00:00:00
abstract：:We previously found that ginsenoside Rd (GSRd), one of the main active ingredients in Panax Ginseng, attenuates H(2)O(2)-induced oxidative injury in PC12 cells. Mounting evidence suggests that the oxidative stress is crucially involved in the pathophysiologic process of ischemia. In the present study, we examined the ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2009.03.016
更新日期：2009-07-01 00:00:00
abstract：:Cytokines have been implicated in the etiology or pathology of various psychiatric diseases of developmental origin such as autism and schizophrenia. Leukemia inhibitory factor (LIF) is induced by a variety of brain insults and known to have many influences on mature and immature nervous system. Here, we assessed the ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2003.12.001
更新日期：2004-03-01 00:00:00
abstract：:Our purpose was to elucidate the functional roles of the laryngeal afferents in controlling vocalization. We investigated the effects of laryngeal deafferentation (sectioning the internal branch of the superior laryngeal nerve (ISLN)) on respiration and voice quality during electrically-induced vocalization in twelve ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(95)00877-v
更新日期：1995-03-01 00:00:00
abstract：:We examined the number and size of motoneurons and myelinated nerve fibers innervating the medial gastrocnemius (MG) muscle in the hindlimb of rats that were subjected to swimming for 10 months (30 min, 3 days/week) from 17 to 27 months of age. The number of MG motoneurons in exercised aged rats was slightly, but not ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(98)00026-1
更新日期：1998-05-01 00:00:00
abstract：:In rat hippocampal CA1 neurons recorded intracellularly from tissue slices, a rapid depolarization occurred approximately 5 min after application of ischemia-simulating medium. In extracellular recordings obtained from CA1 region, a rapid negative-going DC potential (rapid DC potential) was recorded, corresponding to ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(99)00119-4
更新日期：2000-02-01 00:00:00
abstract：:We examined the effects of the odors from mother's milk, other mother's milk and formula milk on pain responses in newborns undergoing routine heelsticks. Forty-eight healthy infants were assigned to four groups, an own mother's breast milk odor group (Own MM), another mother's breast milk odor group (Other MM), a for...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2008.10.007
更新日期：2009-01-01 00:00:00
abstract：:Excitatory synaptic transmission from two input systems to hippocampal CA3 pyramidal neurons was investigated by the whole-cell patch-clamp technique for thin slice preparation, with special reference to long-term potentiation (LTP) in these systems. Excitatory postsynaptic currents (EPSCs) evoked by fimbrial stimulat...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(91)90070-f
更新日期：1991-11-01 00:00:00
abstract：:Considerable evidence suggests that an N-methyl-D-aspartate (NMDA) receptor plays a crucial role in memory and cognitive function. To identify the role of this receptor in higher functions of the brain, we delivered antisense oligonucleotides against an NMDA-NR1 subunit (NR1) to the hippocampus in rats using the HVJ-l...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(03)00012-9
更新日期：2003-04-01 00:00:00
abstract：:The cerebellar Purkinje cell has highly branched dendrites extending in a transverse plane to the cerebellar folium. Branching patterns of the dendrites were subjected to fractal analysis to obtain a quantitative measure of their intricacy. Using a square-covering method, we found that dendrites have a statistical sel...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(92)90031-7
更新日期：1992-02-01 00:00:00
abstract：:Maternal stress, viral infection, and obstetric complications, which trigger cytokine signaling, are hypothesized to be involved in schizophrenia and its related disorders. The etiologic contribution of individual cytokines to such psychiatric disorders, however, remains to be evaluated. To estimate the impact of peri...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2004.05.010
更新日期：2004-09-01 00:00:00
abstract：:The influence of tooth loss on the viability of cholinergic neurons was examined in rats. At 25th postnatal week, rats were divided into the three groups; a control group fed a solid diet, a soft diet group fed a powder diet and a molar crown-less group in which all molar crowns were removed and the powder diet was gi...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(02)00063-9
更新日期：2002-08-01 00:00:00
abstract：:Neonatal Brachial Plexus Palsy (NBPP) may lead to permanent impairment of arm function. As NBPP occurs when central motor programs develop, these may be ill-formed. We studied elbow flexion and motor imagery with fMRI to search for abnormal motor programming. We compared the cortical activity of adults with conservati...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2017.05.001
更新日期：2017-10-01 00:00:00
abstract：:Chemokines are a family of peptides originally identified as the factors regulating the migration of leukocytes in inflammatory and immune responses. Recently, they have been shown to be produced in the central and peripheral nervous systems under various pathological conditions and act on neuronal and glial cells. In...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2004.01.004
更新日期：2004-04-01 00:00:00
abstract：:The purpose of this study was to investigate electrophysiological correlates related to the recognition of repeated faces in the intact human by means of event-related brain potentials (ERPs). A group of young healthy adults performed a continuous face recognition task, in which 240 unfamiliar faces were flashed upon ...
journal_title：Neuroscience research
pub_type： 临床试验,杂志文章
doi：10.1016/s0168-0102(97)00047-3
更新日期：1997-07-01 00:00:00
abstract：:Medial preoptic area (MPA), supraoptic nucleus (SON), magnocellular (MaPVN) and parvocellular (PaPVN) paraventricular hypothalamic nuclei, and mesencephalic lateral tegmentum (MLT) are involved in maternal behavior, parturition and lactation. This study investigated the FosB and Fos immunoreactivity in these regions o...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(98)00100-x
更新日期：1998-12-01 00:00:00
abstract：:The disposition of the facial vibrissae of the mouse is represented as a matrix-like array of cell aggregates in rows and columns at every station of the whisker-to-barrel pathway. In order to evaluate the role of each station in this pathway, lesions were made in the facial vibrissae of the mystacial group on P0-P3, ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(95)00969-Z
更新日期：1995-11-01 00:00:00
