Interaction between paired-pulse facilitation and long-term potentiation in the projection from hippocampal area CA1 to the entorhinal cortex.

abstract：:Both amyloid-β peptide (Aβ) deposition and neuroinflammation are considered to be early events that play pivotal roles in Alzheimer's disease (AD) pathogenesis and its associated cognitive impairment. Prophylactic anti-Aβ active immunotherapy is a promising therapeutic strategy for AD, if the Aβ-specific autoimmune re...

journal_title：Neuroscience research

authors： Ding L,Meng Y,Zhang HY,Yin WC,Yan Y,Cao YP

更新日期：2017-06-01 00:00:00

abstract：:Our purpose was to elucidate the functional roles of the laryngeal afferents in controlling vocalization. We investigated the effects of laryngeal deafferentation (sectioning the internal branch of the superior laryngeal nerve (ISLN)) on respiration and voice quality during electrically-induced vocalization in twelve ...

journal_title：Neuroscience research

authors： Shiba K,Yoshida K,Miura T

更新日期：1995-03-01 00:00:00

abstract：:During brain development, neural stem cells change their competency to give sequential rise to neurons and glial cells. Expression of the basic helix-loop-helix (bHLH)-type cell-fate determination factors Ascl1, Olig2, and Hes1 is oscillatory in neural stem cells. Conversely, sustained expression of these factors medi...

journal_title：Neuroscience research

authors： Kageyama R,Shimojo H,Ohtsuka T

更新日期：2019-01-01 00:00:00

abstract：:Spinal reflex arcs mediated by low threshold afferents between the brachioradialis (BR) and flexor carpi radialis (FCR) were studied in eleven healthy human subjects using a post-stimulus time-histogram method. Electrical conditioning stimuli (ES) to the radial nerve branch innervating BR with the intensity below the ...

journal_title：Neuroscience research

authors： Kobayashi S,Hayashi M,Shinozaki K,Nito M,Hashizume W,Miyasaka T,Shindo M,Naito A

更新日期：2016-09-01 00:00:00

abstract：:Action potentials, when arriving at presynaptic terminals, elicit Ca(2+) influx through voltage-gated Ca(2+) channels. Intracellular [Ca(2+)] elevation around the channels subsequently triggers synaptic vesicle exocytosis and also induces various protein reactions that regulate vesicle endocytosis and recycling to pro...

journal_title：Neuroscience research

authors： Yamashita T

更新日期：2012-05-01 00:00:00

abstract：:Neonatal Brachial Plexus Palsy (NBPP) may lead to permanent impairment of arm function. As NBPP occurs when central motor programs develop, these may be ill-formed. We studied elbow flexion and motor imagery with fMRI to search for abnormal motor programming. We compared the cortical activity of adults with conservati...

journal_title：Neuroscience research

authors： Anguelova GV,Rombouts SARB,van Dijk JG,Buur PF,Malessy MJA

更新日期：2017-10-01 00:00:00

abstract：:Properties of the Ca2+ -activated K+ current (I[K(Ca)]) were investigated in bipolar cells isolated from the goldfish retina. Pharmacological experiments and single channel current recordings demonstrated that I[K(Ca)] represented currents through BK channels, which were confined mostly to the presynaptic terminal. Th...

journal_title：Neuroscience research

authors： Sakaba T,Ishikane H,Tachibana M

更新日期：1997-03-01 00:00:00

abstract：:Trans-2,4-dimethoxystibene (S(3)) is a synthetic stilbene. In this study, S(3) was investigated in terms of its neuroprotective effect against the toxicity induced by beta-amyloid(25-35) (Abeta(25-35)) both in vitro and in vivo. Protection by S(3) was studied at the in vivo level using a model of intracerebroventricul...

journal_title：Neuroscience research

authors： Ruan CJ,Zhang L,Chen DH,Li Z,Du GH,Sun L

更新日期：2010-07-01 00:00:00

abstract：:The organization of the sagittal Zone C of the cerebellar cortex of the rat was studied with respect to its efferent projections and to its inferior olive (IO) afferent connections. Wheat-germ agglutinin conjugated to horseradish peroxidase was used as a tracer. Zone C has been defined as the cortical region projectin...

journal_title：Neuroscience research

authors： Buisseret-Delmas C

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Global field synchronization (GFS) has recently been introduced to measure functional synchronization in frequency-domain EEG data. This study explored GFS values and its clinical significance in patients with Alzheimer's disease (AD). METHOD:EEGs were recorded from 22 AD patients and 23 age-matched healthy...

journal_title：Neuroscience research

authors： Park YM,Che HJ,Im CH,Jung HT,Bae SM,Lee SH

更新日期：2008-10-01 00:00:00

abstract：:Resveratrol shows ability to eliminate prion replication, but the exact mechanism for prion eradication was not clear yet. Our previous studies demonstrate a downregulation of brain-derived nerve growth factor (BDNF) during prion infection, meanwhile recovery of cerebral nerve growth factor (NGF) level by resveratrol ...

journal_title：Neuroscience research

authors： Hu C,Chen C,Chen J,Xiao K,Wang J,Shi Q,Ma Y,Gao LP,Wu YZ,Liu L,Xia Y,Yan P,Maimaitiming A,Zhou DH,Zhang LN,Chen ZB,Dong XP

更新日期：2021-01-01 00:00:00

abstract：:Neuronal degeneration appears to be associated with changes in anti-ubiquitin immunoreactivity (UIR). To elucidate the relationship between the two events, we examined the time course of changes in UIR in pyramidal neurons of hippocampal organotypic cultures following exposure to an excitotoxin, N-methyl-D-aspartate (...

journal_title：Neuroscience research

authors： Okada M,Sakaguchi T,Kawasaki K

更新日期：1995-07-01 00:00:00

abstract：:The interaction of neurotransmitter receptors with the underlying cytoskeleton via subsynaptic proteins is an important mechanism for the targeting of the receptors to synapses in the central nervous system. We show that delta glutamate receptors (delta receptors), expressed predominantly in the dendritic spines of ce...

journal_title：Neuroscience research

authors： Hirai H,Matsuda S

更新日期：1999-09-01 00:00:00

abstract：:Damage to the central nervous system (CNS) leads to disruption of the vascular network, causing vascular dysfunction. Vascular dysfunction is the major event in the pathogenesis of CNS diseases and is closely associated with the severity of neuronal dysfunction. The suppression of vascular dysfunction has been conside...

journal_title：Neuroscience research

authors： Muramatsu R,Yamashita T

更新日期：2014-04-01 00:00:00

abstract：:A disynaptic projection from the spinal cord to the striatum was observed in the rat light and electron microscopically. An anterograde tracer, wheat germ agglutinin conjugated to horseradish peroxidase was injected into the ventral gray matter of the upper cervical spinal cord, and a retrograde tracer, biotinylated d...

journal_title：Neuroscience research

authors： Nakamura Y,Otake K,Tokuno H

更新日期：2006-09-01 00:00:00

abstract：:A time production test was performed in seven normal females and seven females with premenstrual syndrome (PMS). We used a time production test for six time intervals (6, 12, 24, 36, 48, 60 s). Time production tests were performed at 08:00, 14:00 and 20:00 h in the follicular, early luteal and late luteal phases (LLP)...

journal_title：Neuroscience research

authors： Morofushi M,Shinohara K,Kimura F

更新日期：2001-12-01 00:00:00

abstract：:Neuropsin is a serine protease cloned from the mouse hippocampus. Since neuropsin is a secreted protein which effectively cleaves fibronectin, it may affect cell adhesion or cell migration by modulating the content and/or chemical characteriscs of fibronectin in extracellular matrix (ECM). In adhesion assays, alpha5B2...

journal_title：Neuroscience research

authors： Tani N,Matsumoto K,Ota I,Yoshida S,Takada Y,Shiosaka S,Matsuura N

更新日期：2001-02-01 00:00:00

abstract：:In rats with a unilateral 6-hydroxydopamine (6-OHDA)-induced lesion in the nigrostriatal fibers, methamphetamine (3 mg/kg, i.p.) induced Fos-like immunoreactivity (FLI), which was inhibited by pretreatment with N-methyl-D-aspartate antagonist MK-801 (1 mg/kg, i.p.), not only in the medial striatum contralateral to the...

journal_title：Neuroscience research

authors： Ishida Y,Todaka K,Kuwahara I,Nakane H,Ishizuka Y,Nishimori T,Mitsuyama Y

更新日期：1998-04-01 00:00:00

abstract：:We studied the ascending and descending axonal trajectories of excitatory vestibular neurons related to the anterior semicircular canal, by means of local stimulation and spike-triggered signal averaging techniques in anesthetized cats. More than 200 vestibular neurons related to the ampullary nerve of the anterior se...

journal_title：Neuroscience research

authors： Uchino Y,Hirai N

更新日期：1984-10-01 00:00:00

abstract：:Adaptive changes in initial eye velocity of pursuit eye movement were examined in nine normal subjects using a target that moved in a multiple ramp fashion. Significant changes in initial eye velocity occurred rapidly after training in six of the subjects. The magnitude and direction of the induced changes were a func...

journal_title：Neuroscience research

authors： Fukushima K,Tanaka M,Suzuki Y,Fukushima J,Yoshida T

更新日期：1996-08-01 00:00:00

abstract：:We previously showed that our neural stem sphere (NSS) method promotes the neuronal differentiation of mouse, monkey and human embryonic stem (ES) cells. Here we analyzed changes in expression of marker genes and proteins during neuronal differentiation. When cultured in astrocyte-conditioned medium (ACM) under free-f...

journal_title：Neuroscience research

authors： Otsu M,Sai T,Nakayama T,Murakami K,Inoue N

更新日期：2011-04-01 00:00:00

abstract：:The present study was performed to determine whether the voltage gated Cl- channel (CLC) expression is altered in the hippocampus of seizure sensitive (SS) gerbils, and to identify the strong fast paired-pulse inhibition in the dentate gyrus of SS gerbils is associated with altered CLC expression. In the hippocampal p...

journal_title：Neuroscience research

authors： Kim DS,Yoo KY,Hwang IK,Jung JY,Won MH,Choi SY,Kwon OS,Seo JH,Kang TC

更新日期：2005-01-01 00:00:00

abstract：:l-Serine is required for the synthesis of glycine and d-serine, both of which are NMDA receptor co-agonists. Although roles for d-serine and glycine have been suggested in schizophrenia, little is known about the role of the l-serine synthesizing cascade in schizophrenia or related psychiatric conditions. Here we repo...

journal_title：Neuroscience research

authors： Ozeki Y,Pickard BS,Kano S,Malloy MP,Zeledon M,Sun DQ,Fujii K,Wakui K,Shirayama Y,Fukushima Y,Kunugi H,Hashimoto K,Muir WJ,Blackwood DH,Sawa A

更新日期：2011-02-01 00:00:00

abstract：:Electromyograms were recorded from the intralaryngeal muscles (the posterior cricoarytenoid (PCA) and thyroarytenoid (TA) muscles) and the ventilatory muscles (the diaphragm (DA) and abdominal (RA) muscle) during electrically induced vocalization in precollicular postmammillary decerebrate cats. Electrical stimulation...

journal_title：Neuroscience research

authors： Yamanaka Y,Sakamoto T,Wada K,Nakajima Y

更新日期：1993-06-01 00:00:00

abstract：:TDP-43 pathology in motor neurons is a hallmark of ALS. In addition, the reduced expression of an RNA editing enzyme, adenosine deaminase acting on RNA 2 (ADAR2), increases the expression of GluA2 with an unedited Q/R site in the motor neurons of patients with sporadic ALS. As the occurrence of these two disease-speci...

journal_title：Neuroscience research

authors： Yamashita T,Hideyama T,Teramoto S,Kwak S

更新日期：2012-06-01 00:00:00

abstract：:We examined the effects of the odors from mother's milk, other mother's milk and formula milk on pain responses in newborns undergoing routine heelsticks. Forty-eight healthy infants were assigned to four groups, an own mother's breast milk odor group (Own MM), another mother's breast milk odor group (Other MM), a for...

journal_title：Neuroscience research

authors： Nishitani S,Miyamura T,Tagawa M,Sumi M,Takase R,Doi H,Moriuchi H,Shinohara K

更新日期：2009-01-01 00:00:00

abstract：:We suggest a time-varying partial correlation as a statistical measure of dynamic functional connectivity (dFC) in the human brain. Traditional statistical models often assume specific distributions on the measured data such as the Gaussian distribution, which prohibits their application to neuroimaging data analysis....

journal_title：Neuroscience research

authors： Lee N,Kim JM

更新日期：2020-07-03 00:00:00

abstract：:ATP-sensitive K(+) (K(ATP)) channel subunits SUR2A and SUR2B in the rat brain were investigated by RT-PCR assay, western blot analysis, in situ hybridization histochemistry, and immunohistochemical staining. The results show that the mRNA and protein of SUR2A and SUR2B are expressed in whole rat brain extracts and sel...

journal_title：Neuroscience research

authors： Zhou M,He HJ,Tanaka O,Sekiguchi M,Kawahara K,Abe H

更新日期：2012-10-01 00:00:00

abstract：:To elucidate the molecular mechanisms that regulate the maturation of action potential, we began by examining voltage-dependent K+ currents, known to contribute to the maturation of action potential, of developing granule cells in mouse cerebellar microexplant cultures. The migration of developing granule cells in thi...

journal_title：Neuroscience research

authors： Wakazono Y,Kurahashi T,Nakahira K,Nagata I,Takayama C,Inoue Y,Kaneko A,Ikenaka K

更新日期：1997-12-01 00:00:00

abstract：:In the present study we measured cardiovascular and respiratory reflexes evoked by administration of bradykinin and capsaicin into the hindlimb vasculature of anaesthetised rats, whilst simultaneously recording activity of sensory afferents on the adventitial surface of femoral arteries and veins. Bradykinin (0.9 nmol...

journal_title：Neuroscience research

authors： Smith PJ,McQueen DS

更新日期：2004-11-01 00:00:00