Abstract:
:In rats with a unilateral 6-hydroxydopamine (6-OHDA)-induced lesion in the nigrostriatal fibers, methamphetamine (3 mg/kg, i.p.) induced Fos-like immunoreactivity (FLI), which was inhibited by pretreatment with N-methyl-D-aspartate antagonist MK-801 (1 mg/kg, i.p.), not only in the medial striatum contralateral to the lesion but also in the substantia nigra pars reticulata (SNr) ipsilateral to the lesion. Thus, hemispheric asymmetries in FLI were induced by methamphetamine in the medial striatum and the SNr in the 6-OHDA model of turning which may be related to the altered function of glutamatergic transmission.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Ishida Y,Todaka K,Kuwahara I,Nakane H,Ishizuka Y,Nishimori T,Mitsuyama Ydoi
10.1016/s0168-0102(98)00015-7subject
Has Abstractpub_date
1998-04-01 00:00:00pages
355-60issue
4eissn
0168-0102issn
1872-8111pii
S0168010298000157journal_volume
30pub_type
杂志文章abstract::The periaqueductal gray (PAG)-nucleus retroambiguus (NRA) pathway has been known to be involved in the control of vocalization and sexual behavior. To know how the amygdaloid complex influences the PAG-NRA pathway, here we first examined the synaptic organization between the central amygdaloid nucleus (CeA) fibers and...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2008.10.004
更新日期:2008-12-01 00:00:00
abstract::Recently the authors showed that a computational model of visual saliency could account for changes in gaze behavior of monkeys with damage in the primary visual cortex. Here we propose a neural prosthesis to restore eye gaze behavior by electrically stimulating the superior colliculus to drive visual attention. The s...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2013.07.007
更新日期:2014-01-01 00:00:00
abstract::The subthalamic nucleus occupies a position in the indirect pathway of basal ganglia circuit, which plays an important role in the movement regulation. Zolpidem is an imidazopyridine agonist with a high affinity on the benzodiazepine site of GABA(A) receptors containing alpha 1 subunit. Recently, zolpidem has been rep...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2007.02.002
更新日期:2007-05-01 00:00:00
abstract::Increased levels of proinflammatory cytokines have been implicated in schizophrenia; however, their pathophysiological roles in abnormal brain dysfunctions remain unclear. We evaluated the effect of proinflammatory cytokines on a high-fat diet (HFD)-induced prepulse inhibition (PPI) deficits in the acoustic startle re...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2018.10.004
更新日期:2019-10-01 00:00:00
abstract::The purposes of the present study were to determine which upper airway movements cause a difference in the expiratory airflow pathway between sneezing and coughing, and to develop a new animal model for studying the neural mechanism of sneezing in paralyzed animals, i.e. fictive sneezing. We compared the upper airway ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(98)00075-3
更新日期:1998-10-01 00:00:00
abstract::The effects of substance P (SP) on cholinergic transmission were studied at the neuromuscular junction of frogs by intracellular and voltage-clamp recording methods. Bath application of SP increased the amplitude of end-plate potential (e.p.p.) evoked in either low-Ca2+ -high Mg2+ or curare-containing solution. SP at ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(86)90020-9
更新日期:1986-05-01 00:00:00
abstract::The disposition of the facial vibrissae of the mouse is represented as a matrix-like array of cell aggregates in rows and columns at every station of the whisker-to-barrel pathway. In order to evaluate the role of each station in this pathway, lesions were made in the facial vibrissae of the mystacial group on P0-P3, ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(95)00969-Z
更新日期:1995-11-01 00:00:00
abstract::Changes in levels of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and neurotrophin-3 (NT-3) in various regions of the rat brain following kainic acid-induced seizure activity were investigated. BDNF protein, as measured by a two-site enzyme immunoassay, increased transiently 12-24 h after the in...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(99)00059-0
更新日期:1999-10-01 00:00:00
abstract::The present study focused on the early stages of acute glutamate (L-Glu)-induced neurotoxic mechanisms, both biochemical, e.g. intracellular reactive oxygen species (ROS) and associated parameters as well as gene expression of cell survival/death pathways, i.e. Bcl-2 and caspases. Stereotactic intracortical injections...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2009.11.009
更新日期:2010-03-01 00:00:00
abstract::Sleep disturbances are common in psychiatric disorders, but the causal relationship between the two and the underlying genetic factors is unclear. The DISC1 gene is strongly linked to mood disorders and schizophrenia in a Scottish pedigree. In an earlier study we found a sleep homeostasis disturbance in a Drosophila m...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2016.06.006
更新日期:2016-11-01 00:00:00
abstract::This work was aimed to assess whether voluntary exercise rescued behavioral and hippocampal alterations in mice lacking the lysophosphatidic acid LPA1 receptor (LPA1-null mice), studying the potential relationship between the amount of exercise performed and its effects. Normal and LPA1-null mice underwent 23 days of ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2013.09.004
更新日期:2013-11-01 00:00:00
abstract::To investigate the functional organization in the monkey inferotemporal cortex, which is the last exclusively visual area along the ventral visual cortical pathway, optical imaging based on intrinsic signals was carried out. We first conducted single-cell recordings with microelectrodes and determined the features cri...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(98)00062-5
更新日期:1998-09-01 00:00:00
abstract::The hippocampus communicates with the neocortex via the entorhinal cortex and is thought to be critically involved in the consolidation of memories. This paper contains in vivo evidence of a projection from the hippocampal area CA1 to the entorhinal cortex. Current theories of memory formation suggest that the backpro...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2005.06.009
更新日期:2005-10-01 00:00:00
abstract::This study was conducted to ascertain the possible expression of Fos-like immunoreactivity (Fos-LI) in the postsynaptic dorsal column (PSDC) neurons in response to noxious mechanical stimulation of the forepaw glabrous area of normal rats. For this purpose, Fos immunohistochemistry along with Fluoro-Gold (FG) retrogra...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(01)00245-0
更新日期:2001-08-01 00:00:00
abstract::Mature rat spinal cord cDNA libraries constructed in lambda gt10 and lambda ZAPII were screened with an oligonucleotide probe (39 mer), and 4 clones that possess DNA-inserts encoding a glycine receptor subunit were obtained. The cloned cDNAs were used to reconstruct the nucleotide sequence of the full-length open read...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(91)90064-6
更新日期:1991-06-01 00:00:00
abstract::Pathological gambling (PG) is a non-substance based addiction that shares many behavioral and neural features with substance based addictions. However, in PG behavioral and neural changes are unlikely to be confounded by effects of acute or chronic drug exposure. Changes in reward based decision-making in particular i...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/j.neures.2014.09.008
更新日期:2015-01-01 00:00:00
abstract::Rhotekin, an effector of Rho, is highly expressed in the brain but its function(s) in neurons is almost unknown. In an attempt to define the properties of Rhotekin in neuronal cells, we focused on its interaction with polarity-related molecules. In the present study, we identified a PDZ protein, Lin-7B, as a binding p...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2006.08.003
更新日期:2006-12-01 00:00:00
abstract::There is an endocrinological concern that environmental endocrine disrupters (EEDs) may influence sexual differentiation. Bisphenol A (BPA), one of EEDs, is released from polycarbonate plastics, and has been detected in the human umbilical cord. In this study, we examined the effect of BPA on the sexual differentiatio...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(02)00251-1
更新日期:2003-03-01 00:00:00
abstract::Executive Functions (EFs) involve a set of high cognitive abilities impairment which have been successfully related to a redox omeostasis imbalance in several psychiatric disorders. Firstly, we aimed to investigate the relationship between executive functioning and some oxidative metabolism parameters in Peripheral Bl...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2015.11.007
更新日期:2016-05-01 00:00:00
abstract::We examined effects of carbachol (CCh), muscarinic receptor agonist, on long-term potentiation (LTP) of field excitatory postsynaptic potential (fEPSP) at Schaffer collateral-CA1 synapse of guinea pig hippocampal slices using extracellular recording technique. Application of 0.1 microM CCh to the slices significantly ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(96)01147-9
更新日期:1997-02-01 00:00:00
abstract::Short-interval intracortical inhibition (SICI) acting on the first dorsal interosseus was measured using paired-pulse transcranial magnetic stimulation (interstimulus interval=2ms) in samples of young and healthy older subjects and correlated with manual dexterity measured with the Purdue Pegboard test and two isometr...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2011.04.004
更新日期:2011-08-01 00:00:00
abstract::While the role of creatine in preventing muscle (peripheral) fatigue for high performance athletes is well understood, its biochemical role in prevention of mental (central) fatigue is not. Creatine is abundant in muscles and the brain and after phosphorylation used as an energy source for adenosine triphosphate synth...
journal_title:Neuroscience research
pub_type: 临床试验,杂志文章
doi:10.1016/s0168-0102(02)00007-x
更新日期:2002-04-01 00:00:00
abstract::The structure of dendritic spines determines synaptic efficacy, a plastic process that mediates information processing in the vertebrate nervous system. Aberrant spine morphology, including alterations in shape, size, and number, are common in different brain diseases. Because of this, accurate and unbiased characteri...
journal_title:Neuroscience research
pub_type: 杂志文章,评审
doi:10.1016/j.neures.2015.02.007
更新日期:2015-07-01 00:00:00
abstract::Chronic muscular limb pain requires the adoption of motor patterns distinct from the classic ipsilateral flexion, crossed extension and corresponding reciprocal inhibitions to acute exteroceptive stimulation. Using selective chemical activation of group III/IV afferents in gastrocnemius-soleus (GS) muscles we investig...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2015.01.003
更新日期:2015-06-01 00:00:00
abstract::The interaction of neurotransmitter receptors with the underlying cytoskeleton via subsynaptic proteins is an important mechanism for the targeting of the receptors to synapses in the central nervous system. We show that delta glutamate receptors (delta receptors), expressed predominantly in the dendritic spines of ce...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/s0168-0102(99)00061-9
更新日期:1999-09-01 00:00:00
abstract::Social categorization plays an important role in provoking the victim's responses to aggressive interactions. Pioneering studies suggested that uncertainty in the perpetrator's hostile intention influences whether ingroup favoritism or the black sheep effect (ingroup strictness) will be manifested to a greater extent....
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2016.01.011
更新日期:2016-07-01 00:00:00
abstract::It has been indicated that Pyk2/Src signaling pathway is involved in modulation of N-methyl-D-aspartate-type (NMDA) glutamate receptor activity. Lithium protects against glutamate-induced excitotoxicity in cultured neurons and in animal models of diseases. The neuroprotection against excitotoxicity afforded by lithium...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2004.04.004
更新日期:2004-08-01 00:00:00
abstract::We investigated the distribution and colocalization pattern of the two corticosteroid receptors, mineralocorticoid receptor (MR) and glucocorticoid receptor (GR), in the hippocampus and hypothalamus, the main target regions of corticosterone in the rat brain, using double immunofluorescence histochemistry in conjuncti...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2004.12.013
更新日期:2005-04-01 00:00:00
abstract::Sizes of neuronal somata in the cat cervical dorsal root ganglia were determined at different levels (C1-C8). The average value and class distribution of mean cell diameter were analyzed. The ganglia from C1 to C5 could be clearly distinguished from those at levels of brachial plexus afferents (C6-C8) with respect to ...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(90)90009-4
更新日期:1990-02-01 00:00:00
abstract::Using standard intracellular recording techniques 38 nonpyramidal cells or interneurons have been sampled in hippocampal slices of the rat. Among 38 physiologically identified interneurons, all 27 cells labeled with biocytin were morphologically demonstrated to be nonpyramidal and nongranule cells. The vast majority o...
journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/0168-0102(94)90013-2
更新日期:1994-02-01 00:00:00