Functional properties of strychnine-sensitive glycine receptors expressed in Xenopus oocytes injected with a single mRNA.

abstract：:Some evidence suggests that sleep deprivation might impair synaptic plasticity and produce oxidative stress in the hippocampus. However it is not clear whether impairment of long-term potentiation depends on the oxidative stress evoked by sleep deprivation protocol. In this study we aimed to investigate the effects of...

journal_title：Neuroscience research

authors： Süer C,Dolu N,Artis AS,Sahin L,Yilmaz A,Cetin A

更新日期：2011-05-01 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS), which could improve learning and memory, is widely used in psychiatry and neurology as a therapeutic approach. There are few studies reporting effective countermeasures to cognition decline in astronauts during space flight. Accordingly, we examined whether rTMS was...

journal_title：Neuroscience research

authors： Zhai B,Fu J,Xiang S,Shang Y,Yan Y,Yin T,Zhang T

更新日期：2020-04-01 00:00:00

abstract：:The aim of this study was to investigate the differences between children and adults in recognizing facial expressions of simple line drawings of "Chernoff's face". First, the angles of the eyebrows and mouth of Chernoff's face were changed in a stepwise way with a personal computer, and the emotional response of the ...

journal_title：Neuroscience research

authors： Tsurusawa R,Goto Y,Mitsudome A,Nakashima T,Tobimatsu S

更新日期：2008-02-01 00:00:00

abstract：:This study evaluates the efficacy of mifepristone on weight restoration in rats subjected to dietary restriction and methylphenidate administration. 25 female rats aged between 9 and 12 months were divided into 2 groups: 5 controls (exposed only to dietary restriction) and 20 rats that were administered 5 mg/kg/d of m...

journal_title：Neuroscience research

authors： Bou Khalil R,Smayra V,Saliba Y,Hajal J,Bakhos JJ,Souaiby L,Richa S,Tamraz J,Farès N

更新日期：2018-10-01 00:00:00

abstract：:Efferent neurons to the cochlea in the guinea pig were observed in the superior olivary complex and ventral lateral lemniscal nuclei after injection of WGA-HRP into the cochlea via the round window. Of HRP-labeled nerve cells found in the brainstem, about 60% and 10% were located in the ipsilateral lateral superior ol...

journal_title：Neuroscience research

authors： Tokunaga A

更新日期：1988-10-01 00:00:00

abstract：:The purpose of this study was to determine the relationship between the increase in local cerebral blood flow during neuronal activation (evoked LCBF) and the baseline flow level. We measured the hemodynamics in alpha-chloralose-anesthetized rats using laser-Doppler flowmetry during somatosensory stimulation under the...

journal_title：Neuroscience research

authors： Matsuura T,Fujita H,Kashikura K,Kanno I

更新日期：2000-12-01 00:00:00

abstract：:Rhotekin, an effector of Rho, is highly expressed in the brain but its function(s) in neurons is almost unknown. In an attempt to define the properties of Rhotekin in neuronal cells, we focused on its interaction with polarity-related molecules. In the present study, we identified a PDZ protein, Lin-7B, as a binding p...

journal_title：Neuroscience research

authors： Sudo K,Ito H,Iwamoto I,Morishita R,Asano T,Nagata K

更新日期：2006-12-01 00:00:00

abstract：:POZ/BTB proteins influence cellular development and in some examples act as oncoproteins. However, several POZ/BTB transcription factors have been found in terminally differentiated neurons, where their functions remain unknown. One example is NAC1, a constitutively-expressed protein that can regulate behaviors associ...

journal_title：Neuroscience research

authors： Korutla L,Neustadter JH,Fournier KM,Mackler SA

更新日期：2003-05-01 00:00:00

abstract：:A multibarreled glass-coated tungsten microelectrode suitable for single-unit recording and iontophoresis in chronically behaving animals is described. The microelectrode was stiff enough to pass through the dura matter of behaving monkeys, and can be applied as a microiontophoretic electrode. The electrode is easy to...

journal_title：Neuroscience research

authors： Li BM,Mei ZT,Kubota K

更新日期：1990-07-01 00:00:00

abstract：:The change in [Ca2+]i, in a retinal rod outer segment to flash and step stimuli was simulated. The present model included inward and outward calcium fluxes through cation channels and an Na-Ca-K exchanger, respectively, calcium buffers, and diffusion through the interdiskal space of cytoplasm and incisures. Under cont...

journal_title：Neuroscience research

authors： Ichikawa K

更新日期：1996-06-01 00:00:00

abstract：:Adult mammals could spontaneously achieve a partial sensory-motor recovery after spinal cord injury, by mechanisms including synaptic plasticity. We previously showed that this recovery is associated to the expression of synapsin-I, and that sonic hedgehog and Notch-1 could be also involved in plasticity. The role of ...

journal_title：Neuroscience research

authors： Gulino R,Gulisano M

更新日期：2012-07-01 00:00:00

abstract：:Prepulse inhibition (PPI) and habituation of the acoustic startle reflex (ASR) are considered to be candidate endophenotypes of schizophrenia. However, to our knowledge, only one group has investigated these startle measures in Asian patients with schizophrenia. In the present study, we evaluated these startle measure...

journal_title：Neuroscience research

authors： Takahashi H,Iwase M,Ishii R,Ohi K,Fukumoto M,Azechi M,Ikezawa K,Kurimoto R,Canuet L,Nakahachi T,Iike N,Tagami S,Morihara T,Okochi M,Tanaka T,Kazui H,Yoshida T,Tanimukai H,Yasuda Y,Kudo T,Hashimoto R,Takeda M

更新日期：2008-11-01 00:00:00

abstract：:Changes in voltage-dependent Na+ (INa) and Ca2+ currents (ICa) were investigated in PC12 cells cultured without or with either nerve growth factor (NGF) or 8-Br-cAMP for 10 days. Current recordings were made in the whole-cell mode by using the conventional patch-clamp technique under voltage-clamp conditions. Membrane...

journal_title：Neuroscience research

authors： Furukawa K,Onodera H,Kogure K,Akaike N

更新日期：1993-02-01 00:00:00

abstract：:γ-Aminobutyric acid (GABA) generally induces hyperpolarization and inhibition in the adult brain, but causes depolarization (and can be excitatory) in the immature brain. Depolarizing GABA actions are necessary for neurogenesis, differentiation, migration, and synaptogenesis. Additionally, the conversion of GABA respo...

journal_title：Neuroscience research

authors： Fukuda A

更新日期：2020-07-01 00:00:00

abstract：:The distribution of a live attenuated herpes simplex virus (betaH1)-mediated gene delivery into the central nervous system (CNS) was regulated by growth inhibition with ganciclovir (GCV) and the effect of this transgene expression system on the physiologic response was characterized by the acoustic startle response an...

journal_title：Neuroscience research

authors： Fukuda Y,Yamamura J,Uwano T,Nishijo H,Kurokawa M,Fukuda M,Ono T,Shiraki K

更新日期：2003-02-01 00:00:00

abstract：:We previously showed that our neural stem sphere (NSS) method promotes the neuronal differentiation of mouse, monkey and human embryonic stem (ES) cells. Here we analyzed changes in expression of marker genes and proteins during neuronal differentiation. When cultured in astrocyte-conditioned medium (ACM) under free-f...

journal_title：Neuroscience research

authors： Otsu M,Sai T,Nakayama T,Murakami K,Inoue N

更新日期：2011-04-01 00:00:00

abstract：:Neuronal circuits are intensively shaped depending on experiences received during developmental critical periods. How neuronal circuits are sculpted can even affect the later development of higher cognitive functions, such as vocal communication skills. Here, we propose songbirds that learn to sing from early auditory...

journal_title：Neuroscience research

authors： Yazaki-Sugiyama Y

更新日期：2019-03-01 00:00:00

abstract：:Glial cell line-derived neurotrophic factor (GDNF) is a member of the transforming growth factor-beta superfamily and acts as a neurotrophic factor for the nigrostriatal dopamine (DA) system. Although previous studies have shown that pretreatment with GDNF could prevent degenerative changes of nigrostriatal DA system ...

journal_title：Neuroscience research

authors： Aoi M,Date I,Tomita S,Ohmoto T

更新日期：2000-04-01 00:00:00

abstract：:Our purpose was to elucidate the functional roles of the laryngeal afferents in controlling vocalization. We investigated the effects of laryngeal deafferentation (sectioning the internal branch of the superior laryngeal nerve (ISLN)) on respiration and voice quality during electrically-induced vocalization in twelve ...

journal_title：Neuroscience research

authors： Shiba K,Yoshida K,Miura T

更新日期：1995-03-01 00:00:00

abstract：:The human cerebral neocortex is divided into six layers consisting of specific neuronal cell types and connections. To determine the distribution of cortical neurons during early development, we examined the expressions of layer-specific markers in human midterm fetal brains. Layer V marker ZNF312 is expressed in most...

journal_title：Neuroscience research

authors： Zhu H,Yang Y,Gao J,Tao H,Qu C,Qu J,Chen J

更新日期：2010-09-01 00:00:00

abstract：:Properties of the Ca2+ -activated K+ current (I[K(Ca)]) were investigated in bipolar cells isolated from the goldfish retina. Pharmacological experiments and single channel current recordings demonstrated that I[K(Ca)] represented currents through BK channels, which were confined mostly to the presynaptic terminal. Th...

journal_title：Neuroscience research

authors： Sakaba T,Ishikane H,Tachibana M

更新日期：1997-03-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) is a recently identified member of the secretin/vasoactive intestinal polypeptide (VIP) family. There are at least two types of receptor for PACAP: type I (PACAPR), which specifically binds PACAP; and type II (VIP/PACAPR), which binds both PACAP and VIP. The l...

journal_title：Neuroscience research

authors： Shioda S,Shuto Y,Somogyvari-Vigh A,Legradi G,Onda H,Coy DH,Nakajo S,Arimura A

更新日期：1997-08-01 00:00:00

abstract：:Withdrawal may be a natural model to study craving and compulsive drug seeking, since craving can be viewed as a conditioned dysphoric state. It has been suggested that functional connectivity between brain areas may be of major value in explaining excessive craving and compulsive drug seeking by providing essential l...

journal_title：Neuroscience research

authors： Fingelkurts AA,Fingelkurts AA,Kivisaari R,Autti T,Borisov S,Puuskari V,Jokela O,Kähkönen S

更新日期：2007-05-01 00:00:00

abstract：:According to the amyloid hypothesis for the pathogenesis of Alzheimer's disease (AD), amyloid beta peptide (Abeta) directly affects neurons, leading to neurodegeneration and tau phosphorylation, followed by the production of paired helical filaments (PHF) in neurofibrillary tangles (NFT). To analyze the relationship b...

journal_title：Neuroscience research

authors： Takashima A,Honda T,Yasutake K,Michel G,Murayama O,Murayama M,Ishiguro K,Yamaguchi H

更新日期：1998-08-01 00:00:00

abstract：:Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic injury. In the present study, we examined the possibility that the n...

journal_title：Neuroscience research

authors： Candelario-Jalil E,Alvarez D,Merino N,León OS

更新日期：2003-10-01 00:00:00

abstract：:The periaqueductal gray (PAG)-nucleus retroambiguus (NRA) pathway has been known to be involved in the control of vocalization and sexual behavior. To know how the amygdaloid complex influences the PAG-NRA pathway, here we first examined the synaptic organization between the central amygdaloid nucleus (CeA) fibers and...

journal_title：Neuroscience research

authors： Oka T,Tsumori T,Yokota S,Yasui Y

更新日期：2008-12-01 00:00:00

abstract：:Recent studies have shown that certain aromatic aldehydes are ligands for olfactory receptors expressed in mammalian sperm cells and induce sperm chemotaxis. Using a conditioning paradigm, the olfactory sensitivity of five CD-1 mice for seven aromatic aldehydes was investigated. With all seven stimuli, the mice discri...

journal_title：Neuroscience research

authors： Larsson L,Laska M

更新日期：2011-12-01 00:00:00

abstract：:The effects of morphine on the reflex discharges in sympathetic efferents recorded from branches of the inferior cardiac nerve (ICN) were studied in rats anesthetized with alpha-chloralose and urethane. Somatocardiac sympathetic A- and C-reflexes were elicited by single shock electrical stimulation of myelinated (A) a...

journal_title：Neuroscience research

authors： Adachi T,Sato A,Sato Y,Schmidt RF

更新日期：1992-12-01 00:00:00

abstract：:ATP-sensitive K(+) (K(ATP)) channel subunits SUR2A and SUR2B in the rat brain were investigated by RT-PCR assay, western blot analysis, in situ hybridization histochemistry, and immunohistochemical staining. The results show that the mRNA and protein of SUR2A and SUR2B are expressed in whole rat brain extracts and sel...

journal_title：Neuroscience research

authors： Zhou M,He HJ,Tanaka O,Sekiguchi M,Kawahara K,Abe H

更新日期：2012-10-01 00:00:00

abstract：:We previously found that ginsenoside Rd (GSRd), one of the main active ingredients in Panax Ginseng, attenuates H(2)O(2)-induced oxidative injury in PC12 cells. Mounting evidence suggests that the oxidative stress is crucially involved in the pathophysiologic process of ischemia. In the present study, we examined the ...

journal_title：Neuroscience research

authors： Ye R,Li N,Han J,Kong X,Cao R,Rao Z,Zhao G

更新日期：2009-07-01 00:00:00