Abstract：
:We examined the number and size of motoneurons and myelinated nerve fibers innervating the medial gastrocnemius (MG) muscle in the hindlimb of rats that were subjected to swimming for 10 months (30 min, 3 days/week) from 17 to 27 months of age. The number of MG motoneurons in exercised aged rats was slightly, but not significantly, greater than that in sedentary aged rats, and the number for both aged groups was significantly less compared to that in middle-aged (17-month-old) rats. The size of motoneuronal somata in the exercised aged rats was significantly larger than that in sedentary aged rats. Morphological parameters (fascicular area, fiber density, and axonal diameter) for the MG nerve in the exercised rats showed intermediate values between those for middle-aged and sedentary aged rats, although all of the differences in the means between groups were not significant. Thus, the overall changes seen in the exercised rats seem less compared to the changes in the sedentary rats, suggesting that long-term moderate exercise retards the progressive changes in motoneurons and peripheral nerves that develop in old age.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Kanda K,Hashizume Kdoi
10.1016/s0168-0102(98)00026-1subject
Has Abstractpub_date
1998-05-01 00:00:00pages
69-75issue
1eissn
0168-0102issn
1872-8111pii
S0168-0102(98)00026-1journal_volume
31pub_type
杂志文章abstract：:Hypnosis often leads people to obey a suggestion of movement and to lose perceived voluntariness. This inexplicable phenomenon suggests that the state of the motor system may be altered by hypnosis; however, objective evidence for this is still lacking. Thus, we used transcranial magnetic stimulation of the primary mo...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2014.05.009
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abstract：:Opiates have been used extensively in the treatment of pain but with the severe side effect of addiction, which is believed to be related to opiates' direct (primary) or indirect (secondary) neurotoxicity. In this study, the effects of opioids on cell growth and apoptosis have been examined in human neuroblastoma cell...
journal_title：Neuroscience research
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doi：10.1016/s0168-0102(97)00080-1
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abstract：:The current study evidenced hypothesis that mitochondrial dysfunction-oxidative stress-dependent apoptotic pathways play a critical role in degeneration of dopaminergic neurons in Parkinson's disease. Model of rotenone-induced parkinsonism in rats produced decrease in striatal complex I activity and reduced glutathion...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2011.08.008
更新日期：2011-12-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2008.03.007
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journal_title：Neuroscience research
pub_type： 杂志文章,评审
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journal_title：Neuroscience research
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journal_title：Neuroscience research
pub_type： 杂志文章,评审
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更新日期：1992-11-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.09.007
更新日期：2006-12-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.01.001
更新日期：2006-05-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(99)00061-9
更新日期：1999-09-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2017.10.002
更新日期：2018-08-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(87)90011-3
更新日期：1987-02-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(01)00245-0
更新日期：2001-08-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(00)00097-3
更新日期：2000-04-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2011.03.008
更新日期：2011-07-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2004.11.008
更新日期：2005-03-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2008.01.008
更新日期：2008-05-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(86)90004-0
更新日期：1986-02-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(98)00033-9
更新日期：1998-06-01 00:00:00
abstract：:Transforming growth factor beta (TGF-beta) is an extracellular signaling molecule known to mediate programmed cell death (PCD) in the developing retina. In the present study, we investigated the expression profiles and activity levels of TGF-beta ligand and TGF-beta receptors (TbetaR) during the successive physiologic...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.07.002
更新日期：2006-10-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2007.04.003
更新日期：2007-07-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
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更新日期：2001-12-01 00:00:00
abstract：:Prepulse inhibition (PPI) and habituation of the acoustic startle reflex (ASR) are considered to be candidate endophenotypes of schizophrenia. However, to our knowledge, only one group has investigated these startle measures in Asian patients with schizophrenia. In the present study, we evaluated these startle measure...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2008.08.006
更新日期：2008-11-01 00:00:00
abstract：:Recent studies have shown that certain aromatic aldehydes are ligands for olfactory receptors expressed in mammalian sperm cells and induce sperm chemotaxis. Using a conditioning paradigm, the olfactory sensitivity of five CD-1 mice for seven aromatic aldehydes was investigated. With all seven stimuli, the mice discri...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2011.08.009
更新日期：2011-12-01 00:00:00
abstract：:The structure of dendritic spines determines synaptic efficacy, a plastic process that mediates information processing in the vertebrate nervous system. Aberrant spine morphology, including alterations in shape, size, and number, are common in different brain diseases. Because of this, accurate and unbiased characteri...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2015.02.007
更新日期：2015-07-01 00:00:00
abstract：:To elucidate the molecular mechanisms that regulate the maturation of action potential, we began by examining voltage-dependent K+ currents, known to contribute to the maturation of action potential, of developing granule cells in mouse cerebellar microexplant cultures. The migration of developing granule cells in thi...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(97)00099-0
更新日期：1997-12-01 00:00:00
abstract：:Dopaminergic neurons of the substantia nigra pars compacta play a major role in goal-directed behavior and reinforcement learning. The study of their local interactions has revealed that they are connected by electrical synapses. Connexins, the molecular substrate of electrical synapses, constitute a multigenic family...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.08.013
更新日期：2006-12-01 00:00:00
abstract：:Amyloid beta (Aβ) peptides are key molecules in the pathogenesis of Alzheimer's disease (AD). The sequential cleavage of amyloid precursor protein (APP) by the β- and γ-secretases generates Aβ peptides; however, the alternate cleavage of APP by the α- and γ-secretases decreases Aβ production. We previously reported th...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2013.11.004
更新日期：2014-02-01 00:00:00
abstract：:Knowledge remains limited about how chronic cathinone exposure impacts dopamine systems in brain reward circuits. In the present study, a binge-like MDPV exposure that impaired novel object recognition (NOR) dysregulated dopamine markers in mesocorticolimbic substrates of rats, with especially profound effects on D1 a...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2019.07.003
更新日期：2020-06-01 00:00:00
abstract：:Effective connectivity analysis has been widely applied to noninvasive recordings such as functional magnetic resonance imaging and electroencephalograms (EEGs). Previous studies have aimed to extract the causal relations between brain regions, but the validity of the derived connectivity has not yet been fully determ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2019.09.003
更新日期：2020-07-01 00:00:00
