Self-sustained circadian rhythm in cultured human mononuclear cells isolated from peripheral blood.

abstract：:Acupuncture of the sacral vertebrae has therapeutic effects in patients with overactive bladders. The mechanism of these effects, however, remains unclear. The present study, using urethane-anesthetized rats, investigated the effects of acupuncture stimulation of the sacral vertebrae on bladder activity and bladder ac...

journal_title：Neuroscience research

authors： Wang H,Tanaka Y,Kawauchi A,Miki T,Kayama Y,Koyama Y

更新日期：2012-01-01 00:00:00

abstract：:Distribution of the delta- and epsilon-subspecies of protein kinase C (PKC) in rat central nervous tissues was semiquantitated by an immunoblot analysis. The epsilon-subspecies, which is expressed predominantly in the brain, was abundant in hippocampus and cerebral cortex among rat brain areas, whereas the delta-subsp...

journal_title：Neuroscience research

authors： Matsushima S,Nakamura S

更新日期：1994-05-01 00:00:00

abstract：:To elucidate the molecular mechanisms that regulate the maturation of action potential, we began by examining voltage-dependent K+ currents, known to contribute to the maturation of action potential, of developing granule cells in mouse cerebellar microexplant cultures. The migration of developing granule cells in thi...

journal_title：Neuroscience research

authors： Wakazono Y,Kurahashi T,Nakahira K,Nagata I,Takayama C,Inoue Y,Kaneko A,Ikenaka K

更新日期：1997-12-01 00:00:00

abstract：:Using immunohistochemistry and retrograde transport techniques, this study demonstrates that serotonin (5-HT) cells in the dorsal tegmental gray of the pons at rostrocaudal from P1 to P6 levels are sources of bilateral serotonergic projections to the gigantocellular tegmental field of the medial pontine and medullary ...

journal_title：Neuroscience research

authors： Kobayashi Y,Matsuyama K,Mori S

更新日期：1994-07-01 00:00:00

abstract：:Effects of 1-naphthyl acetyl spermine (NASPM), a synthetic analogue of Joro spider toxin (JSTX), on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors were studied in cultured rat hippocampal neurons using the whole-cell patch clamp technique. A population of cultured neurons had ...

journal_title：Neuroscience research

authors： Koike M,Iino M,Ozawa S

更新日期：1997-09-01 00:00:00

abstract：:The A5 is an unique membrane protein that is expressed in the neurons of the visual system and general somatic sensory system of Xenopus laevis. We cultured retinal explants or trigeminal ganglion neurons on the monolayers of A5-expressing line cells obtained by transfection with the cDNA, and found that the A5-expres...

journal_title：Neuroscience research

authors： Hirata T,Takagi S,Fujisawa H

更新日期：1993-07-01 00:00:00

abstract：:A disynaptic projection from the spinal cord to the striatum was observed in the rat light and electron microscopically. An anterograde tracer, wheat germ agglutinin conjugated to horseradish peroxidase was injected into the ventral gray matter of the upper cervical spinal cord, and a retrograde tracer, biotinylated d...

journal_title：Neuroscience research

authors： Nakamura Y,Otake K,Tokuno H

更新日期：2006-09-01 00:00:00

abstract：:Basigin (Bsg) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. Chicken Bsg (HT7/neurothelin/ 5A11) is expressed in neuroblasts, but disappears from neurons after a specific stage of cytodifferentiation, and becomes restrictedly expressed in the capillary endothelium in the adult brain. We s...

journal_title：Neuroscience research

authors： Fan QW,Yuasa S,Kuno N,Senda T,Kobayashi M,Muramatsu T,Kadomatsu K

更新日期：1998-01-01 00:00:00

abstract：:Confocal laser scanning microscopy (CLSM) was used to record spatial and dynamic changes in the intracellular Ca2+ [(Ca2+]i) of bullfrog sympathetic ganglion cells in excised tissue or in culture. A CLSM utilizing Ar ion laser (488 nm) and recording fluo-3 fluorescence yielded the sliced image of ganglion cells, while...

journal_title：Neuroscience research

authors： Kuba K,Hua SY,Nohmi M

更新日期：1991-05-01 00:00:00

abstract：:The Approach-Avoidance Task (AAT) measures automatic approach-avoidance tendencies and their regulation: compatible reactions (approach positive, avoid negative) are faster than incompatible ones (approach negative, avoid positive). The present study assessed event-related potentials (ERPs) in 15 healthy persons for d...

journal_title：Neuroscience research

authors： Ernst LH,Ehlis AC,Dresler T,Tupak SV,Weidner A,Fallgatter AJ

更新日期：2013-03-01 00:00:00

abstract：:The structure of dendritic spines determines synaptic efficacy, a plastic process that mediates information processing in the vertebrate nervous system. Aberrant spine morphology, including alterations in shape, size, and number, are common in different brain diseases. Because of this, accurate and unbiased characteri...

journal_title：Neuroscience research

authors： Maiti P,Manna J,McDonald MP

更新日期：2015-07-01 00:00:00

abstract：:Glutamate receptor subtypes mediating excitatory synaptic neurotransmission in the cerebellar cortex are briefly reviewed from molecular biological, electrophysiological and pharmacological points of view. In particular, molecular biological findings of a novel family of AMPA-selective glutamate receptors are introduc...

journal_title：Neuroscience research

authors： Okamoto K,Sekiguchi M

更新日期：1991-01-01 00:00:00

abstract：:Education involves learning new information and acquiring cognitive skills. These require various cognitive processes including learning, memory, and language. Since cognitive processes activate associated brain areas, we proposed that the brains of elderly people with longer education periods would show traces of rep...

journal_title：Neuroscience research

authors： Kim J,Chey J,Kim SE,Kim H

更新日期：2015-05-01 00:00:00

abstract：:Mature rat spinal cord cDNA libraries constructed in lambda gt10 and lambda ZAPII were screened with an oligonucleotide probe (39 mer), and 4 clones that possess DNA-inserts encoding a glycine receptor subunit were obtained. The cloned cDNAs were used to reconstruct the nucleotide sequence of the full-length open read...

journal_title：Neuroscience research

authors： Akagi H,Hirai K,Hishinuma F

更新日期：1991-06-01 00:00:00

abstract：:Since the first analysis of the Drosophila courtship song more than 50 years ago, the molecular and neural mechanisms underlying the acoustic communication between fruit flies has been studied extensively. The results of recent studies utilizing a wide array of genetic tools provide novel insights into the anatomic an...

journal_title：Neuroscience research

authors： Kamikouchi A

更新日期：2013-07-01 00:00:00

abstract：:The actin cytoskeleton plays a critical role in the cellular morphological changes. Its organization is essential for neurite extension and synaptogenesis under the processes of neuronal development. Recently, neural Wiskott-Aldrich syndrome protein (N-WASP) and WASP family verprolin-homologous protein (WAVE) have bee...

journal_title：Neuroscience research

authors： Tsuchiya D,Kitamura Y,Takata K,Sugisaki T,Taniguchi T,Uemura K,Miki H,Takenawa T,Shimohama S

更新日期：2006-12-01 00:00:00

abstract：:To evaluate recovery function of and effects of hyperventilation (HV) on high-frequency oscillations (HFOs) of median nerve somatosensory evoked potential (SEP), we recorded SEPs in 8 Parkinson's disease (PD) patients with enlarged HFOs, 4 myoclonus epilepsy (ME) patients and 10 healthy volunteers (N). SEP was recorde...

journal_title：Neuroscience research

authors： Mochizuki H,Machii K,Terao Y,Furubayashi T,Hanajima R,Enomoto H,Uesugi H,Shiio Y,Kamakura K,Kanazawa I,Ugawa Y

更新日期：2003-08-01 00:00:00

abstract：:We developed a new method to visualize the myeloarchitecture in fresh slices, and investigated the properties of the functional neural connections around the boundary between the primary auditory cortex (area 41) and area 18a in rat cerebral slices. A fresh slice illuminated by near-vertical light was observed with a ...

journal_title：Neuroscience research

authors： Hishida R,Hoshino K,Kudoh M,Norita M,Shibuki K

更新日期：2003-06-01 00:00:00

abstract：:Fifteen rabbits were classically conditioned using stimulation of the right pontine nuclei as a conditioned stimulus and a corneal airpuff as an unconditioned stimulus. After conditioning criterion was reached, the stimulation conditioned stimulus was transferred to the left pontine nuclei and the rate of conditioned ...

journal_title：Neuroscience research

authors： Steinmetz JE,Rosen DJ,Woodruff-Pak DS,Lavond DG,Thompson RF

更新日期：1986-09-01 00:00:00

abstract：:Electromyograms were recorded from the intralaryngeal muscles (the posterior cricoarytenoid (PCA) and thyroarytenoid (TA) muscles) and the ventilatory muscles (the diaphragm (DA) and abdominal (RA) muscle) during electrically induced vocalization in precollicular postmammillary decerebrate cats. Electrical stimulation...

journal_title：Neuroscience research

authors： Yamanaka Y,Sakamoto T,Wada K,Nakajima Y

更新日期：1993-06-01 00:00:00

abstract：:In many studies on functional neuroimaging, change in local cerebral blood flow induced by sensory stimulation (evoked LCBF) is used as a marker for change in cortical neuronal activity, although a full description of the relationship between the evoked LCBF and neuronal activity has not been given. The purpose of thi...

journal_title：Neuroscience research

authors： Matsuura T,Kanno I

更新日期：2001-07-01 00:00:00

abstract：:Intracellular pH (pH(i)) plays an important role in the regulation of central nervous system function. In the present study, we examined whether hydrogen sulfide (H(2)S), a recently recognized neuromodulator, regulates pH(i) in rat primary cultured glia cells. pH(i) was measured with a fluorescent sensitive dye, BCECF...

journal_title：Neuroscience research

authors： Lu M,Choo CH,Hu LF,Tan BH,Hu G,Bian JS

更新日期：2010-01-01 00:00:00

abstract：:Almost all organisms on Earth have an internal biological clock, known as the circadian clock. This clock system drives robust oscillations in metabolism, physiology, and behavior, such as hormone secretions, blood pressure, and sleep/wake cycles, with a period of approximately 24h. In mammals, circadian rhythms are g...

journal_title：Neuroscience research

authors： Yamaguchi Y

更新日期：2018-04-01 00:00:00

abstract：:L-glutamate is the primary excitatory neurotransmitter in the mammalian central nervous system and has also been implicated as a potent neurotoxin. To ensure a high signal-to-noise ratio during synaptic transmission and to prevent neuronal damage that might occur as a result of excessive activation of glutamate recept...

journal_title：Neuroscience research

authors： Tanaka K

更新日期：2000-05-01 00:00:00

abstract：:Maternal stress, viral infection, and obstetric complications, which trigger cytokine signaling, are hypothesized to be involved in schizophrenia and its related disorders. The etiologic contribution of individual cytokines to such psychiatric disorders, however, remains to be evaluated. To estimate the impact of peri...

journal_title：Neuroscience research

authors： Tohmi M,Tsuda N,Watanabe Y,Kakita A,Nawa H

更新日期：2004-09-01 00:00:00

abstract：:TDP-43 pathology in motor neurons is a hallmark of ALS. In addition, the reduced expression of an RNA editing enzyme, adenosine deaminase acting on RNA 2 (ADAR2), increases the expression of GluA2 with an unedited Q/R site in the motor neurons of patients with sporadic ALS. As the occurrence of these two disease-speci...

journal_title：Neuroscience research

authors： Yamashita T,Hideyama T,Teramoto S,Kwak S

更新日期：2012-06-01 00:00:00

abstract：:The cranial nerves and the brain fiber systems of the medaka (Oryzias latipes) fry are revealed by a whole-mount staining method. Newly hatched fry of an albino strain of the medaka were fixed, partially digested with trypsin, treated in 1% Triton X-100, and finally immunohistochemically stained using anti-neurofilame...

journal_title：Neuroscience research

authors： Ishikawa Y,Hyodo-Taguchi Y

更新日期：1994-06-01 00:00:00

abstract：:The cyclic nucleotides perform a variety of roles in the formation and remodeling of the neuronal interaction. The membrane microdomain called "raft" has been paid much attention, for this domain contains many signal-transducing molecules including trimeric G proteins and cytoskeletal proteins. The raft domain is reco...

journal_title：Neuroscience research

authors： Noyama K,Maekawa S

更新日期：2003-02-01 00:00:00

abstract：UNLABELLED:Angiotensin II receptors (Ang II), classified into AT1 and AT2 subtypes, are located in different regions of the central nervous system, including the cardiovascular control centers in the medulla oblongata. We previously reported the role of Ang II AT1 receptors within the medulla on cardiovascular response...

journal_title：Neuroscience research

authors： Tedesco A,Ally A

更新日期：2009-08-01 00:00:00

abstract：:Following neonatal hypoxia-ischemia (HI) serotonin (5-hydroxytryptamine, 5-HT) levels are decreased in the brain. The regulation of brain 5-HT is dependent on the serotonin transporter (SERT) localised at the neuronal pre-synaptic cell membrane. However SERT can also traffic away from the cell membrane into the cytoso...

journal_title：Neuroscience research

authors： Wixey JA,Reinebrant HE,Buller KM

更新日期：2012-07-01 00:00:00