Abstract：
:The cranial nerves and the brain fiber systems of the medaka (Oryzias latipes) fry are revealed by a whole-mount staining method. Newly hatched fry of an albino strain of the medaka were fixed, partially digested with trypsin, treated in 1% Triton X-100, and finally immunohistochemically stained using anti-neurofilament protein (70K+160K+210K) antibodies. Since both head skin and eyes were colorless in the albino fish, the three-dimensional distribution of of nerve fibers in the brain could be readily observed in whole specimens without interference of pigment cells. All cranial nerves and main fiber systems in the adult fish were differentiated in the fry brain. Using this method, the distribution of nerves to the ocular muscles and the periorbital pit organs was shown.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Ishikawa Y,Hyodo-Taguchi Ydoi
10.1016/0168-0102(94)90079-5subject
Has Abstractpub_date
1994-06-01 00:00:00pages
379-86issue
4eissn
0168-0102issn
1872-8111pii
0168-0102(94)90079-5journal_volume
19pub_type
杂志文章abstract：:Glutamate is the principal excitatory neurotransmitter in the mammalian central nervous system (CNS). Glutamate is first synthesized in the cytoplasm of presynaptic terminals before being loaded into synaptic vesicles, which fuse with the plasma membrane, releasing their contents, in response to neuronal activity. The...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2006.04.016
更新日期：2006-08-01 00:00:00
abstract：:The chemical properties of probes that improve amyloid detection by non-invasive (19)F magnetic resonance imaging (MRI) are of interest. We synthesized benzoxazole compounds with trifluoromethoxy groups, and found that these compounds displayed sharp (19)F nuclear magnetic resonance (NMR) signals in an assay buffer. H...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2008.10.006
更新日期：2009-01-01 00:00:00
abstract：:Axonal transport is the specialized and well-developed intracellular transport system for regulated and/or long-distance transport based on generalized cellular machineries. Among them, slow axonal transport conveys cytoplasmic proteins. The motor molecule, the nature of transporting complex and the transport regulati...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2003.08.005
更新日期：2003-12-01 00:00:00
abstract：:In the vertebrate nervous system, glutamate (Glu) receptors are generally known to cause depolarizing responses. We report here a novel type of Glu response in Purkinje neurons of mouse cerebellar slices, namely glutamate-induced hyperpolarization (GH). This response is not due to activation of inhibitory interneurons...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(92)90047-g
更新日期：1992-12-01 00:00:00
abstract：:Eugenol modulates neuronal activity through actions on voltage-gated ionic channels and/or transient receptor potential channels. We previously suggested that eugenol inhibited cellular (and/or network) mechanisms essential for the maintenance of the respiratory burst activity in a brainstem-spinal cord preparation fr...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2019.06.001
更新日期：2020-06-01 00:00:00
abstract：:Most imaging studies of the enteric nervous system (ENS) that regulates the function of the gastrointestinal tract are so far performed using preparations isolated from animals, thus hindering the understanding of the ENS function in vivo. Here we report a method for imaging the ENS cellular network activity in living...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2019.02.004
更新日期：2020-02-01 00:00:00
abstract：:The effects of morphine on the reflex discharges in sympathetic efferents recorded from branches of the inferior cardiac nerve (ICN) were studied in rats anesthetized with alpha-chloralose and urethane. Somatocardiac sympathetic A- and C-reflexes were elicited by single shock electrical stimulation of myelinated (A) a...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(92)90049-i
更新日期：1992-12-01 00:00:00
abstract：:Ethanol's actions in brain have been suggested to be partially mediated by a mechanism involving the ethanol-induced activation of the endogenous opioid system. Opioid systems, which are closely linked with dopamine transmission, are thought to be affected by ethanol through alterations in the processing, release, and...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(03)00188-3
更新日期：2003-10-01 00:00:00
abstract：:Close relationships between the nervous system and immune systems at molecular levels have now become evident. Receptors for CDF/LIF and CNTF, i.e., factors which play important roles in the nervous system, share a close structural similarity to those for IL-6, which is a molecule acting in the immune system. Receptor...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/0168-0102(92)90001-s
更新日期：1992-11-01 00:00:00
abstract：:Neurons in the inferior temporal (IT) cortex respond not only to the shape, color or texture of objects, but to the horizontal positional disparity of visual features in the right and left retinal images. IT neurons with similar shape selectivity cluster in columns. In this study, we examined how IT neurons are spatia...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2003.10.008
更新日期：2004-02-01 00:00:00
abstract：:Excitatory inputs to layer V neurons of the parasubiculum and medial entorhinal cortex were examined in rat brain slices with intracellular and field potential recordings. Single extracellular stimuli to layer V evoked subthreshold excitatory postsynaptic potentials (EPSPs) or a long duration (>100 ms) depolarization ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(01)00306-6
更新日期：2002-01-01 00:00:00
abstract：:In this review, we describe recent experimental observations and model simulations in the research subject of brain-machine interface (BMI). Studies of BMIs have applied decoding models to extract functional characteristics of the recorded neurons, and some of these have more focused on adaptation based on neural oper...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2020.03.008
更新日期：2020-07-01 00:00:00
abstract：:It has been indicated that Pyk2/Src signaling pathway is involved in modulation of N-methyl-D-aspartate-type (NMDA) glutamate receptor activity. Lithium protects against glutamate-induced excitotoxicity in cultured neurons and in animal models of diseases. The neuroprotection against excitotoxicity afforded by lithium...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2004.04.004
更新日期：2004-08-01 00:00:00
abstract：:The facilitatory masseteric muscle response (FMR) elicited by polyurethane foam strip application between the opposing molars during cortically-induced rhythmic jaw movements (CRJMs) was induced earlier than masticatory force onset. The occurrence of this early response of the FMR (e-FMR) could not be explained by a s...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(00)00192-9
更新日期：2001-01-01 00:00:00
abstract：:The Approach-Avoidance Task (AAT) measures automatic approach-avoidance tendencies and their regulation: compatible reactions (approach positive, avoid negative) are faster than incompatible ones (approach negative, avoid positive). The present study assessed event-related potentials (ERPs) in 15 healthy persons for d...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2012.12.005
更新日期：2013-03-01 00:00:00
abstract：:The subiculum is one of output structures of the hippocampal formation and plays a pivotal role in learning and memory. Because its morphological features are less investigated than those of the hippocampus proper, we explored the internal structure of the rat subiculum using immunohistochemistry. The septal subiculum...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2019.02.001
更新日期：2020-01-01 00:00:00
abstract：:Rhotekin, an effector of Rho, is highly expressed in the brain but its function(s) in neurons is almost unknown. In an attempt to define the properties of Rhotekin in neuronal cells, we focused on its interaction with polarity-related molecules. In the present study, we identified a PDZ protein, Lin-7B, as a binding p...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.08.003
更新日期：2006-12-01 00:00:00
abstract：:Acetylcholinesterase (AChE) activity is increased within and around amyloid plaques, which are present in Alzheimer's disease (AD) patient's brain. In this study, using cultured retinal cells as a neuronal model, we analyzed the effect of the synthetic peptide Abeta(25-35) on the activity of AChE, the degradation enzy...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(02)00201-8
更新日期：2003-01-01 00:00:00
abstract：:Glial cell line-derived neurotrophic factor (GDNF) is a member of the transforming growth factor-beta superfamily and acts as a neurotrophic factor for the nigrostriatal dopamine (DA) system. Although previous studies have shown that pretreatment with GDNF could prevent degenerative changes of nigrostriatal DA system ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(00)00097-3
更新日期：2000-04-01 00:00:00
abstract：:Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic injury. In the present study, we examined the possibility that the n...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/s0168-0102(03)00184-6
更新日期：2003-10-01 00:00:00
abstract：:Excitatory synaptic transmission from two input systems to hippocampal CA3 pyramidal neurons was investigated by the whole-cell patch-clamp technique for thin slice preparation, with special reference to long-term potentiation (LTP) in these systems. Excitatory postsynaptic currents (EPSCs) evoked by fimbrial stimulat...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(91)90070-f
更新日期：1991-11-01 00:00:00
abstract：:Since the first analysis of the Drosophila courtship song more than 50 years ago, the molecular and neural mechanisms underlying the acoustic communication between fruit flies has been studied extensively. The results of recent studies utilizing a wide array of genetic tools provide novel insights into the anatomic an...
journal_title：Neuroscience research
pub_type： 杂志文章,评审
doi：10.1016/j.neures.2013.04.003
更新日期：2013-07-01 00:00:00
abstract：:Various heterotrimeric G protein betagamma subunits (Gbetagamma) are region-specifically expressed in brain where associated with "stress-axis", however, the role of Gbetagamma-mediated signaling in regulating stress is unknown. This study was designed to examine the changes of Gbetagamma expression and Gbetagamma-med...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2006.07.001
更新日期：2006-10-01 00:00:00
abstract：:We carried out voltage-sensitive dye imaging of the guinea pig auditory cortex to determine whether the ongoing and spontaneous activities of the cortex exhibit spatial coherence reflecting the tonotopic organization of the cortex. We used independent component analysis and a signal-plus-noise model to extract ongoing...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2008.01.007
更新日期：2008-05-01 00:00:00
abstract：:Vestibular nuclear neurons that mediate horizontal canal signals to the ipsilateral medial rectus motoneurons were explored in anesthetized and decerebrate rabbits. These neurons were identified by four criteria: (1) they were activated monosynaptically by ipsilateral vestibular nerve stimulation and (2) antidromicall...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(85)90016-1
更新日期：1985-08-01 00:00:00
abstract：:The effects of iontophoretically applied (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD), an agonist of metabotropic glutamate receptors, were examined in rat cerebellar Purkinje cells in vivo. Multibarrel electrodes were used for extracellular recordings of spontaneous single unit discharges and iontop...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(93)90057-w
更新日期：1993-12-01 00:00:00
abstract：:We investigated the neural mechanisms underlying the ability to cope in atypical or novel situations using tools. We hypothesized that two cognitive components support this ability: adaptive coordination (for adapting to situational demands) and cognitive inhibition (for inhibiting the incongruent actions afforded by ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2014.03.008
更新日期：2015-01-01 00:00:00
abstract：:The hypothalamic paraventricular nuclei (PVN) inhibits spinal nociception. Furthermore, projections from the PVN to other structures related to pain modulation exist, but a functional interaction has not yet been fully demonstrated. As an initial approach, we show here that PVN electric stimulation with the same param...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2015.04.004
更新日期：2015-09-01 00:00:00
abstract：:This study was to aim at investigating the potential interaction for the serotonin receptor gene (5-HTR) 2A and serotonin transporter gene (5-HTTLPR) polymorphisms in the development of schizophrenia, as well as the interaction of the two polymorphisms in relation with symptomatology, family history, age of onset and ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/j.neures.2005.03.006
更新日期：2005-06-01 00:00:00
abstract：:In an attempt to test the possibility that sino-aortic baroreceptors may mediate the previously reported stress response in hypothalamic magnocellular neurosecretory cell activity in rats, effects of deafferentation of sino-aortic baroreceptors on plasma levels of vasopressin and oxytocin after fear-related emotional ...
journal_title：Neuroscience research
pub_type： 杂志文章
doi：10.1016/0168-0102(92)90059-l
更新日期：1992-04-01 00:00:00
